• Journal of Animal Science and Technology
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• v.45 no.1
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• pp.101-112
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• 2003

This study was conducted to investigate the effect of the level of concentrates and pasture grazing in 60 head of spring born Hanwoo heifers(initial body weight; 125.3kg) for 450days from six to 21 months in age. Feeding trial was conducted with 5 treatment(twelve heads/ treatment) which were T1(1.5% of apparent body weight in concentrates and indoor feeding for over-all period), T2(0.5% of apparent body weight in concentrates for pre-pasture grazing and pasture grazing), T3(1.0% of apparent body weight in concentrates for pre-pasture grazing and pasture grazing), T4(1.5% of apparent body weight in concentrates for pre-pasture grazing and pasture grazing), T5(2.0% of apparent body weight in concentrates for pre-pasture grazing and pasture grazing). During the total experimental period, average daily gains by treatments ranged from 0.322 to 0.465kg(average 0.405kg) and higher in the order of T5, T4, T1, T3 and T2, and increased with the level of concentrates feeding for pre-pasture grazing. TDN intakes required per unit of kilogram gain were 9.13 to 9.79kg(average 9.49kg) higher in the order of T1, T3, T5, T4 and T2, For the grazing period, they were ranged from 12.39 to 12.98kg(average 12.68kg), and were not significantly different. But TDN requirements of grazing groups was higher about 15.6% than the indoor feeding group’s. The rate of roughage to concentrates by treatments were 57.8 to 73.6%(average 63.7%). The body weight of 15 and 21 month in ages, that is, the ages at puberty and first conception by treatments were 201.2 to 230.7kg(average 223.8kg) and 270.2 to 331.4kg (average 307.6kg), respectively, and the latter were high per unit of 20.4kg by increasing the level of concentrates feeding for pre-pasture grazing every 0.5% addition of apparent body weight. The age of 225 and 275kg in body weight, that is, the body weight at puberty and first conception by treatments were 14.0 to 17.6 month (average 15.3 month) and 17.9 to 21.7 month(average 19.4), respectively, and the latter were shorter about 1.3 month by increasing the level of concentrates feeding every 0.5% addition of apparent body weight. According to the above results, it may be concluded that spring born Hanwoo heifers are raised at indoor have to feed with 1.8% of body weight in concentrates under full feeding of rice straws for all period from six to 21 months in age, but with 1.5% of apparent body weight in concentrates for grazing period.

• Journal of the Korean Applied Science and Technology
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• v.9 no.1
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• pp.41-46
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• 1992

The transesterification of dimethylphthalate by 1,4-butanediol was kinetically investigated In the presence of various metal acetate catalysts at 180$^{\circ}C$. The quantity of dimethylphthalate reacted in the reaction flask was measured by gas chromatography. The transesterification was assumed to obey first-order kinetics with respect to dimethylphthalate and 1,4-butanediol, and a rate equation was derived. The linear relationship was shown between apparent rate constant and reciprocal absolute temperature, the activation energy has been calculated as 7.4kcal with lead acetate. The maximum reaction rate was appeared at the range of 1.5${\sim}$1.6 of electronegativity of metal ions.

• BMB Reports
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• v.30 no.2
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• pp.113-118
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• 1997

Aspartase from Hafnia alvei was inactivated by N-ethylmaleimide (NEM) and 5,5' -Dithiobis-(2-znitrobenzoic acid) (DTNB) following pseudo-first order kinetics. Their apparent reaction orders were 0.83 and 0.50 for NEM and DTNB modifications, respectively, indicating that inactivation was due to a sulfhydryl group in the active site of aspartase and participation of the sulfhydryl group in an essential step in the catalytic reaction. When aspartase was modified by DTNB, the enzyme activity was restored by dithiothreitol treatment, indicating that cysteine residuetsl islarel possibly at or near the active site. The pH-dependence of the inactivation rate by NEM suggested that an amino acid residue having pK value of 8.3 was involved in the inactivation. When aspartase was incubated with NEM and L-aspartate together, L-aspartate markedly protected the enzyme from inactivation by NEM, but the other reagents used did not.

• IE interfaces
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• v.15 no.4
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• pp.338-348
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• 2002

In this paper, we present a restricted tabu search(RTS) algorithm that schedules jobs on identical parallel machines in order to minimize the maximum lateness of jobs. Jobs have release times and due dates. Also, sequence-dependent setup times exist between jobs. The RTS algorithm consists of two main parts. The first part is the MATCS(Modified Apparent Tardiness Cost with Setups) rule that provides an efficient initial schedule for the RTS. The second part is a search heuristic that employs a restricted neighborhood generation scheme with the elimination of non-efficient job moves in finding the best neighborhood schedule. The search heuristic reduces the tabu search effort greatly while obtaining the final schedules of good quality. The experimental results show that the proposed algorithm gives better solutions quickly than the existing heuristic algorithms such as the RHP(Rolling Horizon Procedure) heuristic, the basic tabu search, and simulated annealing.

• Journal of Pharmaceutical Investigation
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• v.15 no.1
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• pp.40-44
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• 1985

The stability of ftorafur in artificial gastric juice and its major decomposition product were studied quantitatively by the combination of TLC technique and UV-recording spectrophotometry. The decomposition proceeded in first-order reaction. The decomposition rate was accelerated by the increase of temperature. The major decomposition products were identified as 5-fluorouracil. The apparent activation energy for the decomposition was found to he approximately 24.3kcal/mole from Arrhenius plot.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.51 no.9
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• pp.451-459
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• 2002

This paper presents a method for modelling of the impedance locus in order to test the protective relay with dynamic. This paper has the two parts, the first part is the configuration of impedance locus with voltage magnitude, total impedance magnitude and angle. And the second part is the control of the locus speed with deviation of two frequencies. The proposed method is applied to two machine equivalent system with PSCAD/EMTDC to show its effectiveness.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.14
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• pp.397-426
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• 2000

Since the internet is open to public in 1990, electronic commerce(EC) user has increase rapidly. Now EC is considered not only as communication method but also as new economical activities. EC is a kind of new commerce model which uses electronic means. And EC has global characteristics so that many country's legislation which regulates it differently makes an obstacle to vital of EC. The purpose of this study is to examine legal problems of internet electronic commerce. First, there are some legal problems whether electronic document has same legal function like traditional documents. Second, electronic signature must has authenticity, integrity, non-repudiation, writing and confidentiality in order to use looks like common signature. Finally, electronic contract is concluded on principle of mutual agreement. It is apparent that the concept of arrival is applied to the date and place in conclusion of electronic contract.

• Biomolecules & Therapeutics
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• v.8 no.4
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• pp.332-337
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• 2000

Physicochemical properties of aspalatone (acetylsalicylic acid maltol ester, AM), which has been recently found to have an antithrombotic effect, were studied in terms of solubility, dissolution, partition coefficient (Pc) and stability. The solubility of AM at 37$^{\circ}C$ was about 1.2 mg/ml and the P$_{c}$ value for n-octanol/water and chloroform/water was 11.4 and 382.6, respectively. Dissolution rates of AM at pH 1.2 and 6.8 were more than 80% within 30 min. The degradation of AM followed apparent first-order kinetics, and was dependent on temperature, pH and ionic strength. From the pH-rate profile, the optimal pH was found to be at around 4.0. Half-lives at pH 1.2 and 6.8 were 33.5 and 44.4 hr, respectively. The degradation rate of AM at pH 1.2 was somewhat faster than that of aspirin, but at pH 7.0, the degradation rate of AM was slower than that of aspirin.n.

• Journal of Pharmaceutical Investigation
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• v.18 no.4
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• pp.203-208
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• 1988

The stability and solubility of piroxicam in propylene glycol (PG), polyethylene glycol (PEC), and PG-water cosolvents have been studied by using high performance liquid chromatography. The degradation rate followed an apparent first-order kinetic and the reaction rate constants at 70, 80, and $90^{circ}C$ were determined. From these rate constants, the activation energy and the rate constant of piroxicam at $25^{circ}C$ in pure PG calculated by Arrhenius equation were 23.34 kcal/mole and $7.0\;{\times}\;10^{-4}\;day^{-1}$, respectively. Both of PG and PEG increased the solubility of the drug, but PEG was more effective.

• Communications for Statistical Applications and Methods
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• v.31 no.1
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• pp.105-127
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• 2024

We propose recurrent neural network (RNN) methods for forecasting realized volatility (RV). The data are RVs of ten major stock price indices, four from the US, and six from the EU. Forecasts are made for relative ratio of adjacent RVs instead of the RV itself in order to avoid the out-of-scale issue. Forecasts of RV ratios distribution are first constructed from which those of RVs are computed which are shown to be better than forecasts constructed directly from RV. The apparent asymmetry of RV ratio is addressed by the Piecewise Min-max (PM) normalization. The serial dependence of the ratio data renders us to consider two architectures, long short-term memory (LSTM) and gated recurrent unit (GRU). The hyperparameters of LSTM and GRU are tuned by the nested cross validation. The RNN forecast with the PM normalization and ratio transformation is shown to outperform other forecasts by other RNN models and by benchmarking models of the AR model, the support vector machine (SVM), the deep neural network (DNN), and the convolutional neural network (CNN).