Journal of Pharmaceutical Investigation
- Volume 18 Issue 4
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- Pages.203-208
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- 1988
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
The Stability of Piroxicam in Propylene Glycol
프로필렌글리콜에서의 피록시캄의 안정성
- Shin, Young-Shin (College of Pharmacy, Pusan National University) ;
- Shin, Young-Hee (College of Pharmacy, Pusan National University) ;
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Lee, Chi-Ho
(College of Pharmacy, Pusan National University)
- Published : 1988.12.20
Abstract
The stability and solubility of piroxicam in propylene glycol (PG), polyethylene glycol (PEC), and PG-water cosolvents have been studied by using high performance liquid chromatography. The degradation rate followed an apparent first-order kinetic and the reaction rate constants at 70, 80, and
Keywords
- piroxicam;
- stability;
- solubility;
- propylene glycol;
- propylene glycol-water cosolvents;
- polyethylene glycol;
- Arrhenius plots