• The Korean Journal of Vision Science
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• v.20 no.4
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• pp.483-495
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• 2018

Purpose : The purpose of this study is to analyze the factors affecting the mental health of students in the department of optometry by the gender and to provide differentiated help to student life and career guidance. Methods : Questionnaire for 132 students in the department of optometry in Chungcheong region was analyzed and mental health was compared and analyzed by the gender. In this study, a questionnaire by SCL-90-R was used, and all statistical information was statistically processed with a significance level of p<0.05 using SPSS 18.0 (SPSS 18.0 was used for processing statistical information with a significance level of p<0.05). Results : Students of the department of optometry presented mental health problems; somatization was 22.7%, psychasthenia was 28.3% and hostility was 12.8%. Depression and paranoia were 27.7% and 10.2% respectively, followed by interpersonal sensitivity, psychosis, phobia, and anxiety disorder with 14.7%, 10.4%, 5.9% and 17.4% respectively. Conclusion : About 28.7% of the students of the department of optometry students experienced somatization, psychasthenia or hostility due to negative mental health and female students ranked relatively higher in all variables than males. Therefore, it is judged that differentiated counseling and guidance in life will be needed for students based on their gender differences.

• Journal of Korean Academy of Oral Health
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• v.41 no.4
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• pp.243-249
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• 2017

Objectives: Stress is a psychological reaction to stimuli such as anxiety or threat felt by a person either physically or mentally when placed in a difficult situation. Although a relationship between stress and dry mouth has been reported, it remains understudied. The purpose of this study was to investigate the association between stress and subjective dry mouth among the elderly living in a rural region. Methods: A total of 214 people aged ${\geq}60years$ living in a rural area were recruited with an informed consent for a cross-sectional analysis. Information about stress and subjective dry mouth was obtained by an interview survey with a constructed questionnaire. Data on other potential confounding factors (including oral factors) such as socio-demographic data, health-related behaviors, the number of remaining teeth, and subjective chewing ability were also gathered at the same time. Logistic regression models were used to analyze the relationship of stress and dry mouth using SPSS. Results: The Crude odds ratio (OR) of stress awareness affecting subjective dry mouth was 2.59 (95% confidence interval: 1.43-4.68). After adjusting for sex, education, income, smoking, and alcohol intake, the adjusted OR was 2.52 (95% confidence interval: 1.30-4.87) which was statistically significant. Conclusions: Elderly people who were stressed had an approximately 2-fold increase in experiencing subjective dry mouth when compared to their stress-free counterparts.

• Journal of Life Science
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• v.33 no.6
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• pp.455-462
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• 2023

During pregnancy, maternal immune activation (MIA) from infection increases the risk of neurodevelopmental diseases, including schizophrenia and autism spectrum disorders. MIA induced by polyinosinic-polycytidylic acid (poly (I:C)) and lipopolysaccharide (LPS) in animal experiments has led to offspring with abnormal behaviors and brain development. In addition, it has recently been reported that microglia, which reside in the brain and function as immune cells, play an important role in behavioral abnormalities and brain development in MIA-induced offspring. However, the underlying mechanism remains unclear. In this study, we investigated whether microglia-specific inhibition of GPR56, a member of the G protein-coupled receptor (GPCR) family, causes behavioral abnormalities in brain development. First, MIA induction did not affect the microglia population, but when examining the expression of microglial GRP56 in MIA-induced fetuses, GPR56 expression was inhibited between embryonic days 14.5 (E14.5) and E18.5 regardless of sex. Furthermore, microglial GPR56-suppressed mice showed abnormal behaviors in the MIA-induced offspring, including sociability deficits, repetitive behavioral patterns, and increased anxiety levels. Although abnormal cortical development such as that in the MIA-induced offspring were not observed in the microglial GPR56-suppressed mice, their brain activity was observed through c-fos staining. These results suggest that microglia-specific GPR56 deficiency may cause abnormal behaviors and could be used as a biomarker for the diagnosis and/or as a therapeutic target of behavioral deficits in MIA offspring.

• Anxiety and mood
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• v.15 no.2
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• pp.61-67
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• 2019

Objective : This study aimed to investigate the general process from the symptom onset to the psychiatric treatment in Korean panic patients and the effect of improved public awareness on it. Methods : This study has a retrospective design. The subjects were the new patients with panic disorder who visited the psychiatric outpatient clinic in twelve university-affiliated hospitals all across Korea. The medical chart was reviewed retrospectively and the data were collected including chief complaints of symptoms, recent stressors, the time to visit the psychiatric outpatient clinic, and visit of other departments and diagnostic approaches for their symptoms. Results : A total of 814 participants were included in the study. The most common department other than psychiatry the panic patients visited were cardiology (28.3%), general internal medicine (16.0%) and neurology (11.4%). The most frequently used diagnostic tests were a echocardiography (17.9%), 24-hour Holter monitoring (11.2%), and brain MRI (8.2%). Only 37.3% of participants visited psychiatric clinic directly. About 80% of participants visited psychiatric department within 1 year after their first panic symptoms and it took $13.8{\pm}13.7weeks$ on average. Comparing before and after 2012, the number of participants increased who visit directly the psychiatric clinic without visiting other departments (p=0.002) and without visiting emergency room (p<0.001). Conclusions : Our results suggest that a substantial number of patients visit departments other than psychiatry when they experience first panic symptoms. However, most patients begin psychiatric treatment within 1 year after their first symptoms and the number of patient are increasing who visit psychiatric department directly without visiting other departments.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.2
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• pp.293-301
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• 2018

This study examined the effects of a multifaceted intervention program on the psychological condition, empowerment, work readiness, and functional capacity for job performance of industrially injured workers. Twelve injured workers in C hospital were included in this study. The subjects participated in a social rehabilitation program 2 hours a day, twice a week, for 8 weeks in total, as well as a work hardening program 3 to 4 hours a day, 5 times a week, for 8 weeks in total. The study was conducted from March to September, 2017. A multi-dimensional psychological examination, empowerment scale, work readiness interview and functional capacity evaluation were conducted and the test scores compared before and after the program with the Wilcoxon signed rank test. In the multi-dimensional psychological examination, there were significant differences in the levels of anxiety, depression, lack of social support, and somatization symptoms (p<.05) except anger. The participants also showed significant differences in the empowerment scale, work readiness scale, and functional capacity evaluation. This study suggests that a multifaceted intervention program can be effective in improving the psychologic condition, empowerment, work readiness, and functional capacity of industrially injured workers and, in turn, may improve their rate of returning to work.

• Journal of Life Science
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• v.24 no.3
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• pp.290-296
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• 2014

The present experiment investigated putative anxiolytic-like effects of quercetin using an elevated plus-maze (EPM) and hole-board apparatus test in mice. Quercetin is a flavonoid widely distributed in nature. Quercetin (1.25, 2.5, 5, or 10 mg/kg) was orally administered to ICR mice 1 h before a behavioral evaluation in the EPM. Control mice were treated with an equal volume of vehicle, and positive control mice were treated with buspirone (2 mg/kg, i.p.). The mice administered quercetin (5 mg/kg) spent a significantly longer percentage of time in the open arms of the EPM and their percentage of entries into the open arms was significantly increased compared to the vehicle-treated controls (p<0.05). The anxiolytic-like activities of quercetin were antagonized by trans-4-aminocrotonic acid (a $GABA_{A-{\rho}}$ agonist, 20 mg/kg) but not by flumazenil (a $GABA_A$ antagonist, 10 mg/kg) or WAY-100635 (a $5-HT_{1A}$ antagonist, 0.3 mg/kg). Moreover, there were no changes in the locomotor activity or myorelaxant effects in any group compared with the vehicle-treated controls. In the hole-board apparatus test, the number of head-dips increased significantly in the single treatment with quercetin (5 mg/kg) group compared to the vehicle-treated controls (p<0.05). These findings suggest that quercetin can promote anxiolytic-like activity, mediated by the GABAergic nervous system, in mice.

• Journal of the Korean Data and Information Science Society
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• v.26 no.6
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• pp.1327-1334
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• 2015

Cancer pain is a very important factor in cancer patients refractory to drop the quality of life of cancer patients. The worldwide trend is an integrated effort by both the western medicine and korean traditional medicine of treatment increases to reduce cancer pain. There are many studies related to cancer pain through an integrated medicine approach. Many study was reported that acupuncture treatment is effective for fatigue, xerostomia, insomnia, anxiety and quality of life. However, despite the practical clinical effects and various case reports of acupuncture, many still disagree about the significance of an integrated treatment of pain reduction with acupuncture. Therefore, we has identified that reduce effect of comprehensive and integrative treatment using acupuncture for cancer pain through publication review. And we evaluated effect of comprehensive and integrative treatment using acupuncture through summary of values in each publication.

• Korean Journal of Soil Science and Fertilizer
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• v.43 no.1
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• pp.44-50
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• 2010

This study was carried out to analyze physico-chemical properties and to determine stability of the 19 commercially available horticultural substrates in Korea by European standard methods (EN methods). The average pH, EC, T-N, $P_2O_5$ were 5.44, 0.62$dS{\cdot}m^{-1}$, 0.98% and 10.54$mg{\cdot}L^{-1}$, respectively. Dry bulk density and particle density were in the range of 124.47~243.16$kg/m^3$ and 2073.94~2249.99$kg/m^3$, respectively. Seventeen out of 19 horticultural substrates used in this study were 'very stable'. The other2 substrates were classified as 'stable'. Korea's own criteria of stability for the organic materials such as growing substrates and compost need to be developed so that farmers can use the optimum organic materials without anxiety.

• Journal of the Korean Applied Science and Technology
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• v.38 no.2
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• pp.378-388
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• 2021

This study investigated the effect of Ego-resilience, Marital communication, and Mental health on Happiness among middle-aged women Methods: A descriptive correlation study design was used with a convenience sample consisting of 239 women. SPSS Win21.0 program was used for the descriptive analysis, t-test, ANOVA, Pearson's correlation coefficient analysis, and multiple-regression analysis. The mean score for ego-resilience was 3.46±.527(range: 1-5), marital communication was 2.44±.52(range: 1-5), mental health 1.82±.66(range: 0-4) and happiness was 3.21±56(ranse: 1-5). Happiness was found to have a significant positive correlation with ego-resilience(r=.393, p<.001) and negative correlation with somatization(r=-.134 p=.039), depression(r=-.356, p<.001), anxiety(r=-.269, p<.001). The predictive factors on the Happiness were depression(β=-.437, p<.001), ego-resilience(β=.350, p<.001), Somatization(β=.239, p=.009) and subjective health status: average (β=-.150, p=.009), unhealthy(β=-.147, p=.015). The explanatory power was 30.4% (F=14.02, p <.001). Based on the findings of this study, it is important to provide services to ego-resilience and mental health among middle aged women.

• Journal of the Korea Society of Computer and Information
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• v.26 no.1
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• pp.239-251
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• 2021

Traditional Chinese medicine has treated diseases and improved health in nature-based experience. Advanced nations began to be interested in naturopathic therapy in the late 19th century and it led China to research aromatherapy. This study searched previous researches related with aromatherapy and generally analyzed aroma oil, applied body parts, methods of use, and period of use. For research contents, scientific and society journals from 2000 to 2019 related with aromatherapy were searched in CNKI(www.cnki.com) and WANFANG DATE(www.wanfang.com). Finally, 30 papers were selected through 5-step qualitative evaluation and expert review and analyzed. Frequency and percentage(%) were calculated by means of the Excel 2013 Program and represented by a chart. The results of analyzing aromatherapy trends are as follows. All 30 papers were researched in the medical society. The most common symptom was irritation and anxiety that appeared in 13 papers. Lavender oil and bergamot oil were commonly used aroma oil. Commonly applied part and method were nose and nasal inhalation. For aroma oil associated with symptoms, lavender oil was the best in irritative, anxious, and negative emotion, depression, labor pain, sleep disorder, migraine, tension, and vomiting, pain, and fatigue after operation. Lemon, ginger, and peppermint oil was good for nausea. Based on the findings, this study derived applied body parts, methods of use, and period of use in aromatherapy. However, most aromatherapy was used for patients in the nursing and medical fields in the simple form of inhalation and local massage. This study will suggest a standard ground that aromatherapy is good for pain, colic pain, and tension in a short period but needs a long period for the efficacy of psychological and neurological symptoms.