• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.1
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• pp.172-182
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• 2005

Objective : The purpose of this study was to know the clinical effect of Hydrotherapy based Ultasonic spa on Atopic Dermatitis and Allergic Rhinitis. Methods : Allery Test(MAST CLA Allergy system, inhalant panel), DITI, Bio Chemistry, Hematology were investigated in 20 patients(Atopic Dermatitis 10, Allergic Rhinitis 10) who visited Department of Ophthalmology & Otolaryngology & Dermatology, Semyung Oriental medicine hospital from November 2004 to January 2005. Results : 1. In atopic dermatitis patients, there was good in 7 cases(70%), excellent in 3 cases(30%). 2. In allergic rhinitis patients there was improved in 5 eases(50%), good in 2 cases(20%), unimproved in 3cases(30%). 3. In conclusion, there was good(doctor and patients ail) in 6(60%), unimproved in 3(30%) Conclusion : Hydrotherapy based Utasonic spa showed useful effect on Atopic Dermatitis and Allergic Rhinitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.3
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• pp.44-54
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• 2005

Background and Objectives: Allergic contact dermatitis is a common environmental health issue and seriously affect the patient's quality of life. The more our environment industrialized, the number of material that could cause the allergic contact dermatitis has been increased, consequently the prevalence of allergic contact dermatitis has been increased. In oriental medicine, clinically Chogam-Tang has been used fur the treatment of allergic dermatitis, eczema, atopic dermatitis etc. The objective of this study is to investigate the effects of Chogam-Tang on allergic contact dermatitis Meterial and Methods: Fifteen Sprague-Dawley rats were divided into three groups: normal, control, experimental group. Control and experimental group were induced allergic contact dermatitis, by DNCB. Experimental group was orally administered the Chogam-Tang. Each group was observed after 24, 48 and 72 hours. Contact hypersensitivity assay, melanin-erythema measurement, pH measurement skin moisture measurement and biopsy were performed. Results: 1. In contact hypersensitivity assay, experimental group showed decreased ear swelling compared with control group at 48hours. 2. ln melanin measurement there was no difference in three groups. 3. In erythema measurement experimental group showed reduction at 48. 72 hours. 4. In pH measurement, experimental group and control group showed increase in pH but there was no statistical significance. 5. In skin moisture measurement, experimental group showed higher skin moisture level than control group at 24 hours and showed lower skin moisture level at 72 hours, but there was no statistical significance. 6. In biopsy, experimental group showed decrement of Iymphocyte as time goes by, and regeneration of keratin layer was increased compared with normal group. Conclusions: Chogam-Tang shows anti-inflammatory effect in biopsy, improves hydration levels of skin, decreases erythema level on allergic contact dermatitis.

• Clinical and Experimental Pediatrics
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• v.63 no.7
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• pp.278-283
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• 2020

Background: Major questions remain regarding the agestratified trends of allergic diseases and asthma in Korea. Purpose: To identify the estimated recent prevalence and 10-year trends in asthma, allergic rhinitis, and atopic dermatitis among the Korean population from 2008 to 2017. Methods: This nationwide cross-sectional survey (Korean National Health and Nutrition Examination Survey) over 10 years (2008-2017) examined representative samples of the Korean population (n=85,006) including 2,131 infants, 4,352 preschool children, 12,919 school-age children, 44,200 adults, and 21,404 elderly adults. Results: In the 2016 to 2017 population, the estimated prevalence of asthma was 0.9% in infants, 2.3% in preschool children, 4.1% in school-age children, 2.3% in adults, and 4.1% in the elderly. The estimated prevalence of allergic rhinitis was 9.0%, 20.2%, 27.6%, 17.1%, and 6.9%, respectively. The estimated prevalence of atopic dermatitis was 5.9%, 11.3%, 14.6%, 3.9%, and 1.6%, respectively. Ten-year trends revealed a significant decrease in asthma prevalence in infants, preschool children, and the elderly. and in atopic dermatitis prevalence in infants and preschool children (P<0.05 for all trends). Furthermore, 10-year trends demonstrated a significant increase in allergic rhinitis prevalence in school-age children, adults, and the elderly, and in atopic dermatitis prevalence in school-age children and the elderly (P<0.05 for all trends). Conclusion: These results improve our understanding of the age-stratified epidemiology of allergic diseases in Korea and suggest the need for the development of tailored and precise strategies to prevent allergic diseases in different age groups.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.3
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• pp.135-144
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• 2015

Objectives : The purpose of this study is to transcribe the effect of Korean medical treatment on nummular dermatitis with allergic dermatitis.Methods : A 42-year-old man patient suffering from nummular dermatitis with allergic dermatitis was treated with herbal medicine, acupuncture, etc. We observed progress of patient with Visual Anologue Scale(VAS) and used comparative observation through camera photographing.Results : After Korean medical treatment, patient's chief complaints with erythema, edema, pruritus, and keratin were significantly declined.Conclusions : Korean medical treatments were an effectual cure for nummular dermatitis with allergic dermatitis.

• Research in Community and Public Health Nursing
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• v.26 no.3
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• pp.230-237
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• 2015

Purpose: This study aimed to assess the prevalence of asthma, allergic rhinitis, and atopic dermatitis in elementary school students according to the body mass index. Methods: This study was conducted as cross-sectional descriptive research using a structured questionnaire. Data were collected from 6,398 students at 15 elementary schools located in Y City in Korea. The cross-sectional survey used the Korean version of International Study of Asthma and Allergies in Childhood questionnaire. Logistic regression analysis was performed to estimate the odds ratios of body mass index. Results: The symptom prevalence of asthma, allergic rhinitis, and atopic dermatitis in the last 12 months was 12.4%, 49.5%, and 24.5%, respectively. The symptom prevalence of asthma was significantly higher in the obesity group. The number of those without any asthma symptom in lifetime was significantly smaller in the overweight (OR=0.70, p=.004) and obesity (OR=0.57, p=.005) groups than in the healthy weight group. Conclusion: These results suggest that asthma, allergic rhinitis, and atopic dermatitis prevention programs for elementary school students should include weight control intervention.

• Journal of Sasang Constitutional Medicine
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• v.13 no.3
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• pp.89-101
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• 2001

1. The purpose of study To study the effectiveness of Yangkyuksanhawtang(YST) against Allergic Contact Dermatitis(ACD) I observed the change of cutaneous shape, histochemistry, immunohistochemistry, and the distribution of apoptotic cells. 2. The material and method of study I divided 4-month-old rats into three groups of 10, which are a contrastive group of having applied Acetone olive oil only, ACD group to have intentionally activated Allergic Contact Dermatitis by DNCB and YST group to give medication of Yangkyuksanhawtang extract. And I observed each group of mice after 24, 48 and 72 hours. 3. The result and conclusion of study The change of cutaneous shape and hypersensitive reaction of immunity was significantly decreased by YST in ACD rats. I consider that YST suppressed hypersensitive reaction of immunity and inflammation in ACD.

• Journal of the Korean Applied Science and Technology
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• v.37 no.1
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• pp.66-75
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• 2020

Atopic dermatitis (AD) usually develops in patients with an individual or family history of allergic diseases, and is characterized by chronic relapsing inflammation seen specially in childhood, association with IgE hyperproduction and precipitation by environmental factors. and wished to examine closely effect that Polygonum multiflorum isolated PM-E and PM-70M orally adminstration used to atopy dermatitis disease patient get in atopy eruption control experimentally. Atopic dermatitis is a chronically relapsing inflammatory skin disease. Animal models induced by relevant allergens play a very important role in the elucidation of the disease. This study was investigated the anti-allergic effect of PM-E and PM-70M on BMAC induced atopic dermatitis in NC/Nga mice. We summerized as the follow. PM-E and PM-70M significantly reduced the skin number of total cell number, CD4⁺ and CD11b⁺/Gr-1 cell compared with positive control and decreased the invasion of CD4⁺ cell in dorsal skin tissue compared with positive control group by using immunohistochemical staining and chemokine such as eotaxin and CCR3 compared with positive control group. PM-E and PM-70M markedly suppressed invasion and edema of leukocytes and mast cell in dorsal skin. Taken together, these findings suggested that PM-E and PM-70M has an anti-allergic activity and this might be useful for the clinical application to treat allergic diseases such as atopic dermatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.209-220
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• 2014

Objectives : The purpose of this study is to report the effect of Korean medicine treatment on occupational allergic contact dermatitis caused by mortar. Methods : The patient treated by herbal medicine, acupuncture, pharmacopuncture and external therapy. The progress is evaluated by Numerical Rating Scale(NRS) and Dermatology Life Quality Index(DLQI). Results : NRS and DLQI score were significantly decreased as a result of Korean medicine treatment. Conclusions : Korean medicine treatment should be effective for the occupational allergic contact dermatitis caused by mortar. More studies are needed to confirm stability of these treatment.

• Clinical and Experimental Pediatrics
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• v.51 no.6
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• pp.640-645
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• 2008

Purpose : It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress. Methods : Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire. Results : A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease. Conclusion : In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.

• Journal of agricultural medicine and community health
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• v.20 no.2
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• pp.187-195
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• 1995

Hwamunsok(mat with flower design) is a special product of Kanghwa, which is made up of cyperus exaltatus. According to Allergy, cyperus exaltatus is one of the inhalant allergens and provokes respiratory symptoms and signs. There have been few reports about respiratory allergic disease or contact dermatitis occurring in farmers who cultivate the cyperus exaltatus or manufacture Hwamunsok with it. We studied the relationship between allergic symptoms and exposure to cyperus exaltatus. First, we questioned 141 voluntaries living in Kangwha on the symptoms of contact dermatitis, allergic rhinitis and bronchial asthma. Secondly, open tests with cyperus exaltatus were done to permitted 73 voluntaries. Patch tests with the European standard series(23 antigens) were only done to exposure 49 subjects to cyperus exaltatus. The results were as follows : 1. As the manifestation rate of allergic symptoms by age, its of 60 years old over in male showed 333 per 1,000 persons. Its of 50 years old in female showed 412 per 1,000 persons. Those age groups in both genders exhibited the highest manifestation of allergic symptoms than all other age groups. Also, if age and sex were adjusted with the rural population of Kanghwagun('93 base population), the manifestation rate of allergic symptoms in male showed 283 per 1,000 persons. Its in female and totals of study populations showed which is each 206 and 234 per 1,000 persons. Specially, it showed that statistics significantly(p=0.002), exposured subjects by cultivation of cyperus exaltatus & manufacture of Hwamunsok have experienced symptoms of contact dermatitis more frequently than unexposured subjects. Secondly, it tested statistics significantly that the risk factor as manifestation of allergic symptoms was the exposure of cyperus exaltatus's allergen(p=0.024). The manifestation risk of allergic symptoms in exposure groups was 3.73 times higher than unexposured subjects. Thirdly, positive reactions in open tests with cyperus exaltatus were higher in exposured subjects than non-exposured subjects. After 72 and 96 hours, positive reactions in open tests were all 10 subjects(20.4%). Also, after 1 week, positive reactions were 8 subjects(16.4%). In conclusion there is a close relationship between contact dermatitis and exposure to cyperus exaltatus while cultivating it and manufacturing Hwamunsok. Therefore, various studies should be continued and a health education program undertaken on contact dermatitis with those who were be engaging in Hwamunsok's manufacture.