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http://dx.doi.org/10.3345/cep.2019.01291

Ten-year trends and prevalence of asthma, allergic rhinitis, and atopic dermatitis among the Korean population, 2008-2017  

Ha, Jihyun (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine)
Lee, Seung Won (Department of Data Science, Sejong University College of Software Convergence)
Yon, Dong Keon (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine)
Publication Information
Clinical and Experimental Pediatrics / v.63, no.7, 2020 , pp. 278-283 More about this Journal
Abstract
Background: Major questions remain regarding the agestratified trends of allergic diseases and asthma in Korea. Purpose: To identify the estimated recent prevalence and 10-year trends in asthma, allergic rhinitis, and atopic dermatitis among the Korean population from 2008 to 2017. Methods: This nationwide cross-sectional survey (Korean National Health and Nutrition Examination Survey) over 10 years (2008-2017) examined representative samples of the Korean population (n=85,006) including 2,131 infants, 4,352 preschool children, 12,919 school-age children, 44,200 adults, and 21,404 elderly adults. Results: In the 2016 to 2017 population, the estimated prevalence of asthma was 0.9% in infants, 2.3% in preschool children, 4.1% in school-age children, 2.3% in adults, and 4.1% in the elderly. The estimated prevalence of allergic rhinitis was 9.0%, 20.2%, 27.6%, 17.1%, and 6.9%, respectively. The estimated prevalence of atopic dermatitis was 5.9%, 11.3%, 14.6%, 3.9%, and 1.6%, respectively. Ten-year trends revealed a significant decrease in asthma prevalence in infants, preschool children, and the elderly. and in atopic dermatitis prevalence in infants and preschool children (P<0.05 for all trends). Furthermore, 10-year trends demonstrated a significant increase in allergic rhinitis prevalence in school-age children, adults, and the elderly, and in atopic dermatitis prevalence in school-age children and the elderly (P<0.05 for all trends). Conclusion: These results improve our understanding of the age-stratified epidemiology of allergic diseases in Korea and suggest the need for the development of tailored and precise strategies to prevent allergic diseases in different age groups.
Keywords
Asthma; Allergic rhinitis; Atopic dermatitis; Korea, Prevalence;
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Times Cited By KSCI : 5  (Citation Analysis)
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1 Pawankar R. Allergic diseases and asthma: a global public health concern and a call to action. World Allergy Organ J 2014;7:12.   DOI
2 Kang SY, Song WJ, Cho SH, Chang YS. Time trends of the prevalence of allergic diseases in Korea: A systematic literature review. Asia Pac Allergy 2018;8:e8.   DOI
3 Sol IS, Kim YH, Kim SY, Choi SH, Kim JD, Kim BO, et al. Prescription patterns and burden of pediatric asthma in Korea. Allergy Asthma Immunol Res 2019;11:280-90.   DOI
4 Song WJ, Wong GWK. Changing trends and challenges in the management of asthma in Asia. J Allergy Clin Immunol 2017;140:1272-4.   DOI
5 Kim BK, Kim JY, Kang MK, Yang MS, Park HW, Min KU, et al. Allergies are still on the rise? A 6-year nationwide population-based study in Korea. Allergol Int 2016;65:186-91.   DOI
6 Yoo B, Park Y, Park K, Kim H. A 9-year trend in the prevalence of allergic disease based on National Health Insurance Data. J Prev Med Public Health 2015;48:301-9.   DOI
7 Cho YM, Kim CB, Yeon KN, Lee ES, Kim K. Trends in the prevalence of childhood asthma in Seoul Metropolitan City, Korea: The Seoul Atopy . Asthma-friendly School Project. J Prev Med Public Health 2018;51:275-80.   DOI
8 Lee JY, Yang HK, Kim M, Kim J, Ahn K. Is the prevalence of atopic dermatitis in Korean children decreasing? : National Database 2009-2014. Asian Pac J Allergy Immunol 2017;35:144-9.
9 Anandan C, Nurmatov U, van Schayck OC, Sheikh A. Is the prevalence of asthma declining? Systematic review of epidemiological studies. Allergy 2010;65:152-67.   DOI
10 Hong S, Son DK, Lim WR, Kim SH, Kim H, Yum HY, et al. The prevalence of atopic dermatitis, asthma, and allergic rhinitis and the comorbidity of allergic diseases in children. Environ Health Toxicol 2012;27:e2012006.   DOI
11 Kim Y. The Korea National Health and Nutrition Examination Survey (KNHANES): current status and challenges. Epidemiol Health 2014;36:e2014002.   DOI
12 Koh HY, Kim TH, Sheen YH, Lee SW, An J, Kim MA, et al. Serum heavy metal levels are associated with asthma, allergic rhinitis, atopic dermatitis, allergic multimorbidity, and airflow obstruction. J Allergy Clin Immunol Pract 2019;7:2912-5.   DOI
13 Lee SW, Yon DK, James CC, Lee S, Koh HY, Sheen YH, et al. Short-term effects of multiple outdoor environmental factors on risk of asthma exacerbations: Age-stratified time-series analysis. J Allergy Clin Immunol 2019;144:1542-50.   DOI
14 Noh H, An J, Kim MJ, Sheen YH, Yoon J, Welsh B, et al. Sleep problems increase school accidents related to allergic diseases. Pediatr Allergy Immunol 2020;31:98-103.   DOI
15 Yon DK, Lee SW, Ha EK, Lee KS, Jung YH, Jee HM, et al. Serum lipid levels are associated with allergic rhinitis, nasal symptoms, peripheral olfactory function, and nasal airway patency in children. Allergy 2018;73:1905-8.   DOI
16 Yang HJ, Song DJ, Shim JY. Mechanism of resistance acquisition and treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children. Korean J Pediatr 2017;60:167-74.   DOI
17 Moon JS, Lee SY, Nam CM, Choi JM, Choe BK, Seo JW et al. 2007 Korean National Growth Charts: review of developmental process and an outlook. Korean J Pediatr 2008;51:1-25.   DOI
18 Yon DK, Hwang S, Lee SW, Jee HM, Sheen YH, Kim JH, et al. Indoor exposure and sensitization to formaldehyde among inner-city children with increased risk for asthma and rhinitis. Am J Respir Crit Care Med 2019;200:388-93.   DOI
19 Boulet LP. Asthma education: an essential component in asthma management. Eur Respir J 2015;46:1262-4.   DOI
20 Park M, Wu P, Goldstein E, Joo Kim W, Cowling BJ. Influenza-associated excess mortality in South Korea. Am J Prev Med 2016;50:e111-e119.   DOI
21 Yoon J, Cho HJ, Lee E, Choi YJ, Kim YH, Lee JL, et al. Rate of humidifier and humidifier disinfectant usage in Korean children: a nationwide epidemiologic study. Environ Res 2017;155:60-3.   DOI
22 Yoon J, Lee SY, Lee SH, Kim EM, Jung S, Cho HJ, et al. Exposure to humidifier disinfectants increases the risk of asthma in children. Am J Respir Crit Care Med 2018;10.
23 Asher MI, Montefort S, Bjorksten B, Lai CK, Strachan DP, Weiland SK, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006;368:733-43.   DOI
24 Zhang Y, Zhang L. Increasing prevalence of allergic rhinitis in China. Allergy Asthma Immunol Res 2019;11:156-69.   DOI
25 Williams H, Stewart A, von Mutius E, Cookson W, Anderson HR; International Study of Asthma and Allergies in Childhood (ISAAC) Phase One and Three Study Groups. Is eczema really on the increase worldwide? J Allergy Clin Immunol 2008;121:947-54.   DOI
26 Yon DK, Cho YS, Ha EK, Jee HM, Song JY, Jung YH, Lee KS, et al. Exposure to phthalates is associated with acute urticaria in children. Pediatr Allergy Immunol 2018;29:657-60.   DOI
27 D'Amato G, Vitale C, Rosario N, Neto HJC, Chong-Silva DC, Mendonca F, et al. Climate change, allergy and asthma, and the role of tropical forests. World Allergy Organ J 2017;10:11.   DOI