• Science of Emotion and Sensibility
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• v.25 no.2
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• pp.101-110
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• 2022

Alcohol abuse negatively affects the individual alcoholics and their families, including children. This paper investigates interventions that help children of alcoholics psychosocially and psychopathologically. We investigated domestic and international literature by searching the related databases and reviewing articles. Inclusion criteria were studies on psychological interventions for children of alcoholics (CoAs) or both CoAs and parents. Results suggest that the interventions help CoAs reduce their emotional and behavioral problems. After the review, the research results were discussed, and suggested further effective interventions. The study is valuable because it reviewed the studies that improved CoAs' psychological problems and suggested future directions

• Journal of Home Health Care Nursing
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• v.19 no.2
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• pp.162-172
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• 2012

Purpose: The purpose of this study is to explore the subjective experiences of relapse and treatment among the alcoholics. Methods: Phenomenological methodology was used for the study. Participants were seven people with inpatient alcoholics at the alcohol treatment center at K hospital in K province. Data were collected via in-depth interviews from March to September, 2012 and analyzed using Colazzi's framework. Results: Six themes and seventeen meanings were formulated for the relapse and treatment experiences of participants with alcoholism. Six themes were 'Lack of true insight', 'Lack of strength to live a life', 'Unable to overcome an urge to drink', 'Being drawn away from others', 'Falling into the powerlessness and despair', and 'Being foothold of self-growth'. Conclusion: The results from this study revealed the relapse experiences among alcoholic patients. Therefore, the findings can provide the framework and direction for developing the relapse prevention program for alcoholic patients. In addition, practitioners in the treatment center or hospital need to consider their relapse and treatment experience.

• Journal of Korean Academy of Nursing
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• v.38 no.5
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• pp.758-767
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• 2008

Purpose: The purpose of this study was to explore and describe life-stories and meanings of life in wives of alcoholics by analyzing their autobiographies. Methods: Autobiographies were collected from 20 participants who produced their own autobiographies in the logotherapeutic autobiography program at community alcohol counseling centers in Korea. The data were coded to identify themes of agency and communion using the manual coding system developed by McAdams, and analyzed by the existential approach. Results: There were 214 coded episodes in twenty autobiographies. There were 128 agency themes and 86 communion themes. The most common themes were Love/Friendship. Five themes emerged from the autobiographical episodes on the existential perspective: 1) overcoming the suffering, 2) meaningful people and relationships, 3) spiritual maturation, 4) caring and helping, and 5) finding a meaning of life. Conclusion: These results showed that the wives of alcoholics who participated in the logotherapeutic autobiography program found the meaning of life through their suffering. Furthermore, a study on existential nursing interventions for people who have meaninglessness in life needs to be done.

• YAKHAK HOEJI
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• v.29 no.1
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• pp.18-26
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• 1985

The present study was undertaken to investigate the possible effect of ginseng butanol fraction on the hepatic acetaldehyde metabolism. Experimental animals were used for the subject of the study. When, in case of mitochondrial aldehyde dehydrogenase (Ald DH), ginseng butanol fraction was added, enzyme activity was increased in a small dose, while, in a large dose, it showed inhibitory effect. In terms of kinetic aspect, ginseng butanol fraction has the effect to decrease the Km values of Ald DH. In vivo studies, the activity of Aid DH increased by induction of acute intoxication of ethanol was further increased through pretreatment with ginseng butanol fraction. When ginseng butanol fraction was given to mice fed with 5% ethanol instead of water for 60 days, the activity of Ald DH in mitochondrial fraction decreased to about 35% in chronic alcoholism, but after pretreatment of ginseng butanol fraction the activity was restored to the control level. By the pretreatment with disulfiram, the Ald DH activity was inhibited in normal and alcohol-treated groups, but after the treatment with ginseng butanol fraction the activity was restored to the control level. The results suggest that ginseng butanol fraction enhance the Ald DH activity inhibited by the treatment of disulfiram with no relation to NAD. It was observed that ginseng butanol fraction markedly decrease the acetaldehyde levels in plasma and liver. All these observations suggested that reduction of acetaldehyde in blood and liver should be dependent upon increased activity of mitochonclrial Ald DH. It is concluded that the recovery from alcohol intoxication should be prompted by treatment with ginseng.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.569-572
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• 2004

Marchiafava-Bignami Disease(MBD) is a rate disease caused by chronic alcohol abuse and involves the degeneration of corpus callosum pathological in character. Until recently there was no method to diagnose MBD except postmortem examination, but nowadays rodiology has advanced increasingly, so MBD can be diagnosed correftly and easily. A case of MBD with stroke symptoms is reported. A 56-year-old man who has been a heavy alcoholic for several years was admitted with stroke symptoms such as stuporous mental, hemi-extremities weakness, dysphasia and dysphagia. After treatment these symptoms were improved.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.6
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• pp.2144-2151
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• 2010

Yoga meditation and music therapy are considered to be appropriate for the spiritual and mental treatment for the patients and employed in many clinics and rehabilitation centers as an alternative medicine. This study aims at the analysis of the effects of yoga and music on the treatment of alcoholism. For this, yoga and music treatments were executed for the patients hospitalized in an alcohol clinic hospital in Gimhae district. Only the patients who were judged as alcohol dependents by a psychiatrist with a diagnostic criteria of DSM-IV participated in the study. During five weeks, from November 10, 2009 to December 29, yoga program was practiced two times per week, totaling 10 times, and music therapy was practiced one time per week, totaling 5 times. Among the patients participated in the programs, 44patients were selected finally. They are 16 patients who performed all the yoga programs, and 28 patients who fulfilled all the music therapies. A survey was conducted on them to estimate the effects of yoga and music treatments for the three cases of 'angry behavior', 'anger expression', and 'psychological state at interview'. The results show that yoga and music treatments have positive effects on the patients, although the statistical significance is not so great. However, the more reliable and significant results could be obtained in further studies by prolongation of the practice period, and by introducing the clinical information such as brain mapping to compensate the emotional bias of the patients.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5709-5714
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• 2014

Background: An association between alcohol/tobacco use and risk of metastasis in breast cancer has been clearly shown. Materials and Methods: The present study explored, in 48 samples of tissue from mammary ductal carcinoma (taken from Mexican women with an average age of $58.2{\pm}10.9$ years), the association of risk of metastasis with the status of hormonal receptors and the c-erbB2 protein (by immunohistochemistry) as well as clinical, histopathological and sociodemographic factors. Results: Of 48 patients, 41.6% (20/48) presented with metastasis, 43.8% were positive for the estrogen receptor (RE+), 31.3% for the progesterone receptor (RP+) and 47.7% for c-erbB2 (c-erbB2+). The following combinations were found: RE+/RP+/c-erbB2+ 8.3%, RE+/RP+ 22.9%, RE+/RP- 20.8%, RE-/RP+ 8.3%, RE-/RP-/c-erbB2- 22.9% and RE-/RP- 47.8%. There were 12 patients who used alcohol/tobacco, of which 91.6% did not present metastasis and 81.9% were RE-/RP-. Compared to the RE-/RP-/c-erbB2+, the RE+/RP+/c-erbB2+ group had a 15-fold greater risk for metastasis (95%CI, 0.9-228.8, p=0.05). The carriers of the double negative hormonal receptors had a 4.7 fold greater probability of being (or having been) smokers or drinkers (95%CI, 1.0-20.4, p = 0.03). Conclusions: There was a clear protective effect of using alcohol and/or tobacco, in the cases included in the present study of mammary ductal carcinoma, associated with double negative hormonal receptors. However, this association could be due to a protective factor not measured (Neyman bias) or to a bias inherent in the rate of hospitalization (Berkson fallacy). This question should be explored in a broad prospective longitudinal study.

• Journal of Music and Human Behavior
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• v.11 no.2
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• pp.19-39
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• 2014

This study investigated whether a song psychotherapy based on the change stages of alcohol addiction impacted the change readiness of alcoholics. The song psychotherapy intervention consists of six activities (listening to a song, singing, songwriting, song sharing, lyrics analysis, and discussion and analysis of a song), which considers the change stages of alcohol addiction. A total of 64 inpatients diagnosed with alcoholism were randomly assigned to either the control (n = 33) or experimental group (n = 31). The experimental group took part in the intervention program for 45 minutes twice a week for 6 weeks (total of 12 sessions). The intervention effect was evaluated with SOCRATES-K. The results showed that the SOCRATES-K score significantly increased by 14.6% (p < .001) for the experimental group, whereas it remained almost unchanged (0.8% increase, p = .141) in the control group. For subcategory scales, the experimental group showed the highest increase in the ambivalence factor, followed by the recognition and taking-steps factors. Meanwhile, no significant changes in all three scales were found in the control group. Therefore, the song psychotherapy intervention based on the change stages of alcohol addiction was found to significantly increase the change readiness of alcoholics.

• Journal of Life Science
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• v.30 no.3
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• pp.260-266
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• 2020

Alcohol impacts many central nervous systems, such as dopamine, serotonin, opioids, and gamma-aminobutyric acid (GABA), leading to addiction. Many studies have investigated the relationship between GABA and alcoholism. The purpose of this study was to investigate the effects of GABA high and low rice intake on the alcohol intake behavior of mice. Black sticky rice with giant embryo (BSRGE), black sticky rice (BSR), giant embryo rice (GER), and rice (Rice) were germinated for 48 hr in brown rice. The embryos were then collected and used in the study. The diets were fed to respective C57BL/6 mouse groups ad libitum for 16 days and investigated for 2 hr alcohol intake, 22 hr water intake, 24 hr feed intake, and body weight. As a result of the repeated measure of ANOVA for the daily change of alcohol intake for 2 hr daily between the BSRGE and BSR groups, there was a significant difference in the number of days of intake (DF = 7, F = 4.812, p = 0.026). A significant daily decrease in alcohol intake was observed in the BSRGE group compared to the BSR group. This reduction was consistent from Day 10 to Day 16. Alcohol consumption also significantly decreased in the GER group compared to the Rice group. This decrease was observed from Day 12 to Day 16. In conclusion, BSRGE and GER resulted in decreased alcohol intake in C57BL/6 mice compared to BSR and rice. This suggests that BSRGE may prevent relapse in patients with alcohol use disorder.

• Journal of Korean Clinical Nursing Research
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• v.19 no.3
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• pp.432-442
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• 2013

Purpose: The purpose of this study was to describe restraint use in care of patients with psychiatric disorders in an attempt to avoid unnecessary restraint use and provide information for developing standards regarding restraint use as a therapeutic maneuver. Methods: For this descriptive study, discharge records from N National Mental Hospital in the year 2009 were reviewed by trained nurses during Dec. 24, 2010 and Mar. 31, 2011. There were 596 restrains applied on 232 of 1,322 discharges. Data collected include general characteristic of patients, the frequency of restraint use, time since admission when restraint was applied, time of the day when restraint was applied, duration of restraint application, place of occurrence, reasons for restraint use, and degree of damage to the patent. Work experience of nurses who applied restraints, number of workforce at the time of restraint, and season of the year was also identified. Descriptive statistics, Chi-square test, t-test, ANOVA, $Scheff{\grave{e}}$ and Jonckheere-Terpstra were applied using SPSS 14.0 to analyze the data. Results: There were 596 restraint uses among 232 patients. Restraints were applied most frequently on males in their 40s, patients diagnosed with schizophrenia, and patients repeating admissions more than 6 times. Restraints were frequently applied within first week following admission, between 16:00 and 20:00, and the average duration of restraint was 5 hours. There were significant differences according to diagnoses of patients in the season restraint occured, time, place of occurrence, reason for restraint, and duration of restraint. Patients with alcoholism received longer restraint application. Conclusion: In order to avoid unnecessary restraint use in patients with psychiatric disorders, nurses and other health care team members need to acknowledge a group of patients such as patients with schizophrenia and alcoholism who relatively frequently restrained or receiving longer restraint. Reasonable and careful decision need to be made when applying restraint in the care of patients with alcohol problem.