• 제목/요약/키워드: agglutinin titer

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대구지역 개의 Brucella canis 감염에 대한 세균학적 및 혈청학적 조사 (Bacteriological and serological investigation of Brucella canis infection of dogs in Taegu city, Korea)

  • 박청규;오지연
    • 대한수의학회지
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    • 제41권1호
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    • pp.67-71
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    • 2001
  • A bacteriological and serological investigation was conducted in a commercial breeding kennel in Taegu city in which canine abortion caused by Brucella canis occurred, and the family dogs in this area were also surveyed for Br canis infection during a period from March 1999 to May 2000. Of 195 dogs in the breeding kennel, 50(25.6%) were found to be bacteremic and 82(42.1%) were shown to be positive for canine brucellosis by both bacteriological and serological test. Of 357 family dogs examined, 17(4.8%) had an agglutinin titer of 1 : 160 or higher. Of these 17 dogs, 5(2.8%) were from indoor dogs and 12(6.7%) were from outdoor dogs. Only 2 mongrel dogs(1 female and 1 male) of 17 serologically positive dogs showed an agglutinin titer of 1 : 2560 or higher and Br canis was isolated from their blood.

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소아에서 Mycoplasma pneumoniae pneumonia에 합병된 한냉응집소 용혈성 빈혈 1례 (A Case of Cold Agglutinin Hemolytic Anemia Complicating Mycoplasma pneumoniae pneumonia in Children)

  • 조성옥;박현진
    • Pediatric Infection and Vaccine
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    • 제5권2호
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    • pp.302-307
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    • 1998
  • Hemolytic anemia due to cold agglutinin disease is a known complication of Mycoplasma pneumoniae infection but is rarely observed, particularly in children. A case of Mycoplasma pneumonia complicated with hemolytic anemia is presented. A 7 year-old girl was adimitted because of fever, cough, sputum and pale appearance. Chest X-ray showed pneumonic consolidation of Rt. upper lobe, lingular division. Laboratory studies disclosed the following values : Hb 5.3g/dL, Hct 11.1%, reticulocyte 2.9%, indirect Coombs test negative, direct Coombs test(monovalent) Anti-C3d positive, Anti-IgG negative, Anti-IgM negative, cold agglutinin titer 1 : 256, mycoplasma antibody titer 1 : 640, total bilirubin 1.0mg/dL. Initial PBS before wanning showed agglutination of red blood cells. The diagnosis of cold agglutinin hemolytic anemia complicating mycoplasma pneumonia was made. And treatment with roxithromycin, prednisolone and avoiding cold exposure was initiated, and complete recovery ensued. We report a case of cold agglutinin hemolytic anemia complicating mycoplasma pneumonia in children.

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한냉응집소를 가진 환자에서의 개심술 1례 보고 (Open heart surgery in a patient with a cold agglutinin)

  • 박영식
    • Journal of Chest Surgery
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    • 제22권2호
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    • pp.305-307
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    • 1989
  • Cold agglutinins are a potential danger to patients who must be subjected to hypothermia. A patient with a cold agglutinin of moderate titer but broad thermal amplitude was to undergo hypothermia during double valve replacement. She was managed preoperatively with plasmapheresis 5 times. There was no complication during and after operation.

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타액 면역글로부린과 치아우식의 상관관계에 관한연구 (A STUDY OF SALIVARY IMMUNOGLOBULIN AND DENTAL CARIES)

  • 김정식
    • Restorative Dentistry and Endodontics
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    • 제9권1호
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    • pp.37-49
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    • 1983
  • This study was undertaken to observe the relationship between salivary IgA, IgG, agglutinin titer & dental caries. The subjects divided into two groups, an active caries group (AC group) and caries-free and treated caries group (CFTC group). The AC group consisted of 36 subjects who had one or more carious lesions and the CFTC group of 12 subjects who had no evidence of caries or had filled teeth without present carious teeth for the last six months. The IgA, IgG and IgM levels in their saliva were measured by single radial immunodiffusion method using a disposable low-level immunodiffusion plate. The salivary agglutinin titers to Streptococcus mutans were measured by microtitration system. The results were as follow; 1. The mean value of IgA concentration in saliva of AC group was slightly higher than that of CFTC group, but its difference was slight. 2. The mean value of IgG concentration in saliva of AC group was slightly lower than that of CFTC group. The IgM concentration in saliva of both groups was neither below 1.1 mg/dl nor detected on LC partigen immunodiffusion plate. 3. There was no difference in the agglutinin titer to S. mutans antigen by serotypes, but low level agglutinin to type d was measured in both groups. 4. AC group showed low correlation between IgA, IgG & DMFT, but CFTC group revealed negative correlation. 5. The relationship between salivary IgA & agglutinin titers to S. mutans was low correlation in AC group, but CFTC group showed significant positive correlation. (P<0.05) 6. There were no specific correlations among the concentrations of salivary immunoglobulins, agglutinin titers to S. mutans, and the DMF teeth. They had no close concern to induce the dental caries.

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송아지 대장균 백신개발에 관한 연구 (Studies on Protective Efficacy of Escherichia coli Vaccines)

  • 안재문;곽학구;김홍기
    • 한국동물위생학회지
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    • 제15권1호
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    • pp.26-31
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    • 1992
  • The oil emulsion and alhydrogel vaccines were prepared from a strain of enterotoxigenic Escherichia coli isolated from calves with diarrhea and their protective efficacy and immunogenicity were tested in Guinea-pigs. Enterotoxigenic Escherichia coli, isolated from calves with diarrhea, has K99 and F4l antigen as 46.2% and 50.9% with 48 and 53 strains respectively out of 104 strains. The protective efficacy of the gel and oil vaccines were 60% and 80% respectively. Agglutinin titers to sera of Guinea-pigs vaccinated with experimental gel and oil vaccines peaked at 5 and 6 weeks after vaccination.

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동종면역(同種免疫)에 의한 말항혈청(抗血淸)제조에 관한 연구 (Preparation of equine blood typing reagents by isoimmunization)

  • 한방근;히로시 마츠모토;장덕지
    • 대한수의학회지
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    • 제30권2호
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    • pp.145-156
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    • 1990
  • This study was purposed to produce blood typing reagents for classifing Cheju horse's blood group factors. The blood typing reagents were prepared by immunization of sixteen pairs out of fourty eight heads of Cheju horses, and seventeen different blood typing reagents (anti-$A_1$, A', H, Z, $ZZ_2$, C, J, K, $P_1$, Q, R, S, $T_1$, $N_1$, $U_2$, X and $E_2$) were prepared from equine isoimmunization. The result for the reagent production and the variation of agglutinin and hemolysin titer are as follows: 1. Anti-K, R, S, $N_1$, $U_2$ and X acted exclusively as hemolysins whereas anti-J, $P_1$, $T_1$ and $E_2$ acted exclusively as agglutinins, however, Anti-$A_1$, A', H, Z, $ZZ_2$, C and Q reacted both as hemolysins and agglutinins. 2. Among the antibodies in most of the reagents reacted both as hemolysins and agglutinins, But anti-$A_1$, H, Z, $ZZ_2$ and Q elevated higher agglutin titers than hemolysin titers, Anti-A' and anti-C elevated higher hemolysin titers than agglutinin titers. 3. Complex antibody $A_1U_2$ was adsorbed $U_2$ and unified to $A_1$, while complex antibody X $N_1$ went through an adsorption process and produced simple antibody X and $N_1$, respectively. 4. In the hemolytic reaction, anti-K and anti-R showed the highest titer, In the agglutination reaction, anti-Z and anti-$ZZ_2$ showed the highest titer. 5. In the case of No.138~No.140 horse immunization combination and No.133~No.146 horse immunization combination, Although production of complex antibody $CE_2$ and $JP_1$ were expected, only anti-$E_2$ and anti-J were produced respectively. 6. The degree of elevation of antibody titer was varied by the blood types and by the types of donor and recipient combination. The fast elevating types, slow elevating types and types that never elevate the antibody titer were identified.

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항Mycoplasma 항체와 한냉응집소에 의한 Mycoplasma pneumoniae의 진단학적 의의 (Diagnostic Significance of Cold Agglutinin and Antimycoplasma Antibody for Mycoplasma pneumoniae Infection)

  • 김정숙;이채훈;전창호;배은경;홍석일
    • Journal of Yeungnam Medical Science
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    • 제4권1호
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    • pp.97-103
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    • 1987
  • 1987년 1월에서 동년 7월까지 본 임상병리과에 M. pneumoniae의 감염을 의심하여 한냉응집소와 항Mycoplasma 항체가 소아환자 191명중 추적조사를 시행한 환자 48명을 대상으로 다음과 같은 결과를 얻었다. 1. 한냉응집소 만으로 M. pneumoniae를 진단하는 데에는 유용성이 떨어진다. 2. M. pneumoniae의 감염을 진단하는 데에는 한냉응집소치 보다 항Mycoplasma 항체가 더 감수성이 있는 것으로 나타났다. 3. 초기에 한냉응집소가 정상으로 나타나더라도, 추적조사에서 양성으로 나타날 수 있으므로, 임상적으로 M. pneumoniae의 감염이 의심되면 추적조사가 필요하다. 4. 소아 폐렴에서 M. pneumoniae에 의한 감염이 많으므로(37.5%), 소아 폐렴환자에선 반드시 한냉응집소와 항Mycoplasma 항체 측정을 동시에 할 필요가 있다.

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치석의 혈형물질에 관한 연구 (STUDIES ON BLOOD GROUP SPECIFIC SUBSTANCE IN THE DENTAL CALCULUS)

  • 김종열;엄정문;한성훈
    • 대한치과의사협회지
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    • 제14권7호
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    • pp.581-584
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    • 1976
  • Twenty Four cases of calculus, which were collected feom the patients, were tested by a serological agglutinin absorption test and the following results were obtained. 1) In all observed xases, blood group specific substances were detected, and this results were agreed with blood group of observed patients. 2) Because the α titer of O-serum is somewhat higher than B, we have come to a conclusion that O type and B type results must be reexamined with much more weighted sample than other type cases.

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성인 장염 환자에서의 Yersinia enterocolitica 분리 3예 (Yersinia enterocolitica isolation from three adult enteritis patients)

  • 정윤섭;이희주;이삼열;강진경;문영명
    • 대한미생물학회지
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    • 제15권1호
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    • pp.3-8
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    • 1980
  • Yersinia enterocolitica has been known to be an important enteric pathogen especially in Scandinavian countries and Canada. In Korea, the authors reported the first case of Y. pseudotuberculosis septicemia in 1979. In 1980, three isolates of Y enterocolitica were obtained from 3 adult patients with enteritis, besides the already reported one in a 5-month-old child, during March to June 1980. Difficulty in the isolation was experienced; ie., the organism was isolated only from the SS primary isolation plate in one case and in the other two cases only from the SS plates inoculated with overnight culture of selenite broth. The isolates showed typical cultural and biochemical characteristics except for the nonmotility even at room temperature. Two isolates were indole negative possibly belonging to Wauter's biotype 3 and the other one was indole positive belonging to biotype 2. One patient was tested for the serum agglutinin titer on the 8th hospital day and it was found to be 1:128. All of the isolates were susceptible to chloramphenicol, colistin, gentamicin, kanamycin, tetracyclne, and tobramycin by the Kirby-Bauer disc diffusion method. All of the infections were controled by ampicillin, amoxicillin, amikacin, or gentamicin treatment. It is considered urgent to broaden our knowledge on yersiniosis in Korea not only by isolating, serotyping and biotyping of the organism, but also by surveying serum agglutinin titer of enteritis patients and normal individuals.

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