Acknowledgement
Supported by : 충북대학교병원
Pediatric Infection and Vaccine
- Volume 5 Issue 2
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- Pages.302-307
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- 1998
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- 2384-1079(pISSN)
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- 2384-1087(eISSN)
A Case of Cold Agglutinin Hemolytic Anemia Complicating Mycoplasma pneumoniae pneumonia in Children
소아에서 Mycoplasma pneumoniae pneumonia에 합병된 한냉응집소 용혈성 빈혈 1례
- Jo, Sung Ok (Department of Pediatrics, College of Medicine, Chungbuk National University) ;
- Park, Hyeon Jin (Department of Pediatrics, College of Medicine, Chungbuk National University)
- Published : 1998.11.20
Abstract
Hemolytic anemia due to cold agglutinin disease is a known complication of Mycoplasma pneumoniae infection but is rarely observed, particularly in children. A case of Mycoplasma pneumonia complicated with hemolytic anemia is presented. A 7 year-old girl was adimitted because of fever, cough, sputum and pale appearance. Chest X-ray showed pneumonic consolidation of Rt. upper lobe, lingular division. Laboratory studies disclosed the following values : Hb 5.3g/dL, Hct 11.1%, reticulocyte 2.9%, indirect Coombs test negative, direct Coombs test(monovalent) Anti-C3d positive, Anti-IgG negative, Anti-IgM negative, cold agglutinin titer 1 : 256, mycoplasma antibody titer 1 : 640, total bilirubin 1.0mg/dL. Initial PBS before wanning showed agglutination of red blood cells. The diagnosis of cold agglutinin hemolytic anemia complicating mycoplasma pneumonia was made. And treatment with roxithromycin, prednisolone and avoiding cold exposure was initiated, and complete recovery ensued. We report a case of cold agglutinin hemolytic anemia complicating mycoplasma pneumonia in children.