• 제목/요약/키워드: adverse effect

검색결과 2,315건 처리시간 0.025초

최저임금이 고용에 미치는 영향 (The Effect of the Minimum Wage on Employment in Korea)

  • 이정민;황승진
    • 노동경제논집
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    • 제39권2호
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    • pp.1-34
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    • 2016
  • 본 논문은 2006~2014년 "고용형태별 근로실태조사" 원자료를 이용하여 최저임금 인상이 고용에 미치는 영향을 추정하였다. 본 논문은 최저임금 인상의 영향력이 인구사회학적 집단별로 다르다는 점을 이용하여 최저임금 인상이 고용에 미치는 인과적 효과를 추정하고자 시도하였다. 분석 결과, 최저임금이 1% 상승하면 고용은 주당 44시간 일자리 수 기준으로 약 0.14% 감소하는 것으로 나타났다. 최저임금 인상의 부정적 고용효과는 여성, 고졸 이하, 청년층과 고령층, 근속기간이 짧은 근로자, 5~29인 사업체에서 크게 나타나는 것을 발견하였다.

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야간 영상에서의 빛 번짐 현상을 이용한 교통신호등 인식 (Traffic Light Recognition Based on the Glow Effect at Night Image)

  • 김민기
    • 한국멀티미디어학회논문지
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    • 제20권12호
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    • pp.1901-1912
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    • 2017
  • Traffic lights at night are usually framed in the image as bright regions bigger than the real size due to glow effect. Moreover, the colors of lighting region saturate to white. So it is difficult to distinguish between different traffic lights at night. Many related studies have tried to decrease the glow effect in the process of capturing images. Some studies drastically decreased the shutter time of the camera to reduce the adverse effect by the glow. However, this makes the video too dark. This study proposes a new idea which utilizes the glow effect. It examines the outer radial region of traffic light. It presents an algorithm to discriminate the color of traffic light by the analysis of the outer radial region. The advantage of the proposed method is that it can recognize traffic lights in the image captured by an ordinary black box camera. Experimental results using seven short videos show the performance of traffic light recognition reporting the precision of 96.4% and the recall of 98.2%. These results show that the proposed method is valid and effective.

한약을 복용한 소아에게 발생한 부작용에 대한 연구 (A Study of Side Effects from Korean Herb Medicine on Children)

  • 정선경;곡수영;유선애;이승연
    • 대한한방소아과학회지
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    • 제24권3호
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    • pp.33-42
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    • 2010
  • Objectives: The purpose of this study is to investigate the frequency of side effects, and the range of the side effects from Korean herb medicine on children. Methods: The study has been carried out from 212 children who took Korean herb medicine in Department of Pediatrics, $\bigcirc\;\bigcirc$ Oriental Medical Hospital from September 2009 to February 2010. The study was completed through patients chart review and telephone survey. Results: 1. There were 6 side effect cases on male, and 3 side effect cases on female out of 212 children. The incidence of side effect was 4.2%. 2. The most common side effect was abdominal pain. The most common related organ was digestive organ. 3. The side effect occurred within one to three days after taking Korean herb medicine, and the symptoms were mostly disappeared after taking the Korean herb medicine into divided dose or less dose. Conclusions: The symptom of side effects on children was not as severe as other adverse drug reactions often seen in Western medication. The most common symptom was abdominal pain. Further studies are needed.

pH와 삼투압 변화가 정자운동성에 미치는 영향 (Effect of pH and Osmolarity on the Sperm Motility)

  • 김현우;김세철
    • Clinical and Experimental Reproductive Medicine
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    • 제20권1호
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    • pp.65-70
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    • 1993
  • To maintain a good sperm motility is one of the key factors for the successful artificial insemination in retrograde ejaculation, and the sperm motility has been shown to be affected by various environmental factors, including change in pH and osmolarity. Herein we have analyzed the effect of change in pH and osmolarity in urine and normal saline on sperm motility by Sperm Quality Analyzer and Makler counting chamber. Semen, which sampled by masturbation from a 28 year old male and showed normal finding on semen analysis, was used for this study. The results were as follows: 1. When osmolarity was fixed to 300mOsm, pH did not show a definite effect on the sperm moility. However, the motility was generally a bit better in alkaline urine and saline than in acid, particularly than in pH 5.0. 2. When pH was fixed to 7.5, sperm motility was best in urine and saline of 300mOsm. Hyperosmolarity had more adverse.effect on the motility than hypoosmolarity. 3. The sperm motility was worse in the urine than in saline under the same pH and osmolarity. In conclusion, osmolarity has a definite effect on sperm motility, where as pH has relatively little effect. And certain components of urine other than pH and osmolarity might affect the sperm motility.

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Effect of Workload on Job Stress of Ghanaian OPD Nurses: The Role of Coworker Support

  • Kokoroko, Emmanuel;Sanda, Mohammed A.
    • Safety and Health at Work
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    • 제10권3호
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    • pp.341-346
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    • 2019
  • Background: Although the concept of workload is important to nursing practice, only a few nursing researchers have focused on the issue of workload within the nursing context. Knowledge of how the dynamics of workload affects the job stress of nurses working in a specific unit or department in a hospital setting, and the influence of coworker support on this relationship, still remains limited. This study, therefore examined the effect of workload on job stress of Ghanaian outpatient department nurses and the moderating effect of coworker support on this relationship. Methods: A cross-sectional survey design was used, and questionnaire was used to collect data from a sample of 216 outpatient department nurses from four major hospitals in Ghana. The data collected measured workload, job stress, and coworker support using National Aeronautics and Space Administration (NASA) Task Load Index, job stress scale, and coworker support scale, respectively. Data were analysed using descriptive statistics, correlation, and hierarchical regression. Results: High levels of workload were associated with high levels of job stress of the nurses. Also, higher levels of workload were related to higher levels of job stress for nurses who received high levels of coworker support, but this was not the case for those who received low levels of coworker support (reserve buffering effect). Conclusion: The finding reiterates the adverse effect of workloads on employees' health, and the reverse buffering effect implies that supporting a colleague at work should be conveyed in a positive manner devoid of negative appraisal.

MDCT에 사용되는 조영제의 부작용에 대한 고찰 (Consideration of Adverse Reaction to MDCT Contrast Media)

  • 양원석;신성규
    • 대한방사선기술학회지:방사선기술과학
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    • 제35권1호
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    • pp.51-57
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    • 2012
  • 본 연구는 2007년 1월부터 12월 까지 부산 소재 일개 대학병원에서 MDCT 검사 시 조영제를 주입한 환자 21,178명중 부작용이 발생한 82명을 대상으로 부작용 발생 유형과 증상, 처치방법을 분석한 결과, 대상자 중 남성과 50대 연령층의 부작용 발생 빈도가 높았고, 조영제 양이 130ml 이상일 때, 조영제 주입속도가 2.5ml/sec 초과일 때가 가장 높았다. 월별로는 4, 5월인 봄에, 증상으로는 두드러기(Urticaria)가 많이 나타났다. 부작용의 대처방법으로는 주치의 또는 방사선과 의사의 처치로 증상완화 후 귀가가 가장 많았다. 따라서 검사전 의료진의 충분한 설명과 조영제 사용 동의서 작성의 전산화, OCS와 EMR등의 전산시스템을 이용한 위험환자의 Warning Sign 구동과 페니라민 제재 등을 통한 전처치 등으로 부작용을 예방하고 완벽한 Emergency Kit의 구비, CPR 계통의 확립 등을 통하여 부작용 발생 시 의료진의 신속하고 적절한 응급대처로 환자 처치에 만전을 기하여 환자 만족도 향상을 위해 노력해야 한다고 생각한다.

산조인탕치료가 여성갱년기 수면장애에 미치는 효과 : 체계적 문헌고찰 및 메타분석 (Sanjoin-tang (Suanzaoren decoction) for Insomnia in Menopausal Syndromes: A Systematic Review and Meta-analysis)

  • 전지희;최태영;이명수;송은혜;;박선주
    • 대한예방한의학회지
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    • 제24권1호
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    • pp.1-14
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    • 2020
  • Objectives : The purpose of this systematic review was to investigate the efficacy and safety of Sanjoin-tang (Suanzaoren decoction, SZRD) for insomnia in menopausal syndromes. Method : We searched the following databases: PubMed, Cochrane Library, EMBASE, China National Knowledge Infrastructure (CNKI), Chinese Science and Technique Journals Database (VIP), Wanfang, Research Information Service System (RISS), OASIS, Korean studies Information Service System (KISS), and National Digital Science Library (NDSL) databases. Randomized controlled trials (RCTs) or quasi-RCTs that used SZRD for women in menopause were included. The methodological quality of each RCT was assessed using the risk of bias tool. Results : In total, nine RCTs were finally included. The included RCTs had a high risk of bias across their domains. Three RCTs examined the effects of SZRD compared with western medicine (WM) in insomnia. Three RCTs showed favorable effects of SZRD with insomnia. Infrastructure also showed that SZRD resulted in better clinical WM (RR 1.19, 95% CI 1.07 to 1.32, P=0.001, I2=0%). Four RCTs showed favorable effects of Modified SZRD with insomnia. Infrastructure also showed that Modified SZRD resulted in better clinical WM (RR 1.13, 95% CI 1.04 to 1.23, P=0.004, I2=0%). Among the 4 RCTs, three RCTs showed an equivalent effect on the total Pittsburh Sleep Quality Index (PSQI). The meta-analysis also showed that Modified SZRD had a superior effect on the total of PSQI (total of PSQI : MD -2.55, 95% CI -3.72 to -1.37, P<0.0001, I2=85%). Only 2 trials reported adverse events and none reported severe adverse events. Conclusion : SZRD appears to be safe, but there is insufficient evidence to make a definitive conclusion because only a few studies reported adverse events. Due to the poor methodological quality of the included studies and the small number of trials included, the evidence cannot be reproduced and assessed. Well-designed RCTs with a larger sample size are needed in the future.

LMK02의 Sprague-Dawley 랫드를 이용한 13 주간 반복 경구투여 독성시험 (13 weeks repeated oral dose toxicity studies with LMK02-Jangwonhwan in SD rats)

  • 강형원;장현호;박장호;김태헌;류영수
    • 동의신경정신과학회지
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    • 제23권2호
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    • pp.99-120
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    • 2012
  • Objectives : The oriental medicine Jangwonhwan, a boiled extract of 12 medicinal herbs/mushrooms, has been prescribed to patients with cognitive dysfunction, as originally described in the Korean medical text, DonguiBogam(amnesia chapter). Recently, a modified formula of Jangwonhwan (LMK02-Jangwonhwan) consisting of seven medicinal plants/mushrooms, was shown to reduce the ${\beta}$-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model for Alzheimer's disease. The toxicity of LMK02-Jangwonhwan was investigated in SD rats, by a daily oral administration for 13 weeks and NOAEL(No observed adverse effect dose), a definite toxic dose and target organ, as well. Methods : Quality control of the tablet form of LMK02-Jangwonhwan was established by estimating the indicative components, Ginsenoside Rg3 of Red Ginseng and Decursin of Angelicagigas Nakai. The toxicity of LMK02-Jangwonhwan was investigated in 6 week old, specific pathogen free (SPF), Sprageu-Dawley rats by oral administration. Each test group consisted of 10 male and 10 female rats. The groups received doses of 500, 1,000 or 2,000 mg/kg/day of test substance for 13 weeks. The clinical signs, death rate, body weight, food consumption, ophthalmic examination, urinalysis, hematological and serum biochemistry, organ weight and pathological changes were examined and compared with those of the control group. Results : The 13-week repeated oral treatment doses didn't result in any specific symptoms or death. There were no significant changes in the rat's weight and food consumption. Further, ophthalmic examination, urinalysis, hematological, serum biochemistry test and organ weight revealed no significant differences. Conclusions : The no-observed-adverse-effect level(NOAEL) of LMK02 for male and female Sprague-Dawley rats was determined as 2,000mg/kg/day and the target organ wasn't confirmed. Because no significant adverse effects were observed, the target organ could not be determined.

제왕절개 수술후 통증조절을 위해 PCA를 이용한 정맥과 경막외 Meperidine 투여효과의 비교 (A Comparative Effect of Meperidine between Intravenous and Epidural Patient-Controlled Analgesia for the Postoperative Pain Relief after Cesarean Section)

  • 이병호;채준석;정미영;변형진
    • The Korean Journal of Pain
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    • 제8권2호
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    • pp.257-265
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    • 1995
  • Patient-Controlled Analgesia (PCA) has been widely used for postoperative pain relief. Meperidine is useful for PCA and has efficient analgesia, rapid onset, and low incidence of adverse effect. To compare the analgesic effect, total dose and hourly dose, side effect and neonatal status of breast feeding with meperidine via intravenous or epidural PCA for 48 hours after Cesarean Section, 40 parturient women undergoing elective Cesarean Section were randomly divided into two groups. Each respective group of 20 parturient women received meperidine via one of the intravenous PCA after general anesthesia with enflurane (IVPCA group) and the epidural PCA after general anesthesia with enflurane (IVPCA group) and the epidural PCA after epidural block with 2% lidocaine 20ml combined with general anesthesia with only $N_2O$ and $O_2$ (EpiPCA group) when they first complained of pain in recovery room. Following the administration of analgesic initial dose, parturient women of IVPCA group were allowed intravenous meperidine 10 mg every 8 minutes when they felt pain. The EpiPCA group received additional bolus dose of meperidine 2 mg and bupivacaine 0.7 mg were administered every 8 minutes as requested the patients with hourly continuous infusion of meperidine 4 mg and bupivacaine 1.4 mg. Data was collected during the 48 hours observation period including visual analog scale (VAS) pain scores, total meperidine dose, hourly dose during 48 hours and each time interval, incidence of adverse effect, satisfaction, and neonatal status with breast feeding. VAS pain scores of analgesic effect in EpiPCA group was significantly lower than in IVPCA group at 2 hours after the initial pain after Cesarean Section. Total dose and hourly dose of meperidine significantly reduced in EpiPCA group. Hourly dose of meperidine at each time interval significantly reduced during first 6 hours and from 12 hours to 24 hours in EpiPCA group. The side effects in IVPCA group were mainly sedation, nausea, and local irritation of skin. And EpiPCA group experienced numbness and itching. The degree of satisfaction of parturient women was 88.2 % in IVPCA group and 85.7 % in EpiPCA group. We did not observe any sedation, abnormal behavior, or seizure like activity in any neonates of breast feeding. From the above results we conclude that epidural PCA was more efficiently analgesic, less sedative, and consumptional, and safer for neonate than intravenous PCA, and could be an alternative method to intravenous PCA.

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증속 기어 전동 로터-베어링 시스템의 횡-비틀림 연성 유한요소 로터다이나믹 해석 (A Coupled Lateral and Torsional FE Rotordynamic Analysis of Speed Increasing Geared Rotor-Bearing System)

  • 이안성;하진웅;최동훈
    • 소음진동
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    • 제11권1호
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    • pp.82-88
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    • 2001
  • In a transmission or geared rotor system a coupled phenomenon of lateral and torsional vibrations may occur due to the gear meshing effect. Particularly, in high speed or low vibration and low noise applications of geared rotor systems a coupled rotordynamic analysis is required to precisely predict their dynamic characteristics. In this paper a generalized finite element model of a gear pair element is developed, which actively couples the lateral and torsional vibrations due to the gear meshing effect. In the modeling the generalized forces due to the transmission error. geometrical eccentricities. and unbalances in the gear system are also considered. Then. using the developed gear pair element model a coupled unforced rotordynamic analysis is performed with a prototype 800 RT turbo-chiller rotor-bearing system having a hull-pinion speed increasing gear. Results show that the torsional vibration characteristics experience some changes due to the gear meshing and lateral dynamic coupling effect, but that they have no adverse effect and the lateral ones have no practical changes in an operating speed range.

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