• Journal of Pharmaceutical Investigation
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• 제35권2호
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• pp.81-87
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• 2005

We have prepared karaya gum patches containing ketoprofen and investigated the effect of short-time current pretreatment of skin on the permeability. Hairless mouse skin was treated with current before the patch was mounted on the skin. The effect of current density and current duration on the flux of ketoprofen was studied. The possibility of additive effect with penetration enhancer (PGML) was also investigated. Iontophoretic pretreatment of skin increased the passive flux up to 3 folds at 0.4 $mA/cm^2$ current density, when the matrix contained no PGML. As the duration of current-pretreatment and current density increased, flux increased. PGML increased the average passive flux markedly, about 6 to 12 folds, depending on the concentration in the patch. Current pretreatment further increased the flux from this PGML containing patch, exhibiting additive effect. These results indicate that short-duration current pretreatment of skin can be an useful method for the enhancement of ketoprofen permeability through skin.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2004년도 Proceedings of ISRS 2004
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• pp.574-576
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• 2004

Since variance of noise is important parameter for a noise filter to reduce noise in image and the performance of noise filter is dependent on estimated variance. In this paper, we apply additive noise variance estimation method to estimate variance of speckle noise of synthetic aperture radar (SAR) imagery. Generally, speckle noise is in multiplicative model, logarithmic transformation is then used to transform multiplicative model into additive model. Here, speckle noise is generally modeled as Gamma distribution function with different looks. The additive noise variance estimation is processed in log domain. The synthesis image and real image of SAR are implemented to test and confirm results and show that more accurate estimation can be achieved.

• 응용통계연구
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• 제25권3호
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• pp.403-413
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• 2012

The modifications suggested in Uhm et al. (2011) are studied using a partly parametric version of Aalen's additive risk model. A follow-up time period is partitioned into intervals, and hazard functions are estimated as a piecewise constant in each interval. A maximum likelihood estimator by iteratively reweighted least squares and variance estimates are suggested based on the model as well as evaluated by simulations using mean square error and a coverage probability, respectively. In conclusion the modifications are needed when there are a small number of uncensored deaths in an interval to estimate the piecewise constant hazard function.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 추계 학술발표회 제20권2호
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• pp.585-588
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• 2008

This study investigated fundamental properties of the colored concrete Corresponding to the various temperatures for plasticity and additive volume of the redmud. the results were summarized as following. There was no difference on the air contents and slumpflow at each temperatures for plasticity. The color tone was high in accordance with increase of temperatures for plasticity, but the drying shrinkage length change was shown in the opposite tendency. The slumpflow was gradually declined, but the air content, compressive strength, color ton and drying shrinkage length change were overall increased when the additive volume of the redmud was increased.

• 한국세라믹학회지
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• 제31권7호
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• pp.777-783
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• 1994

Oxidation behavior of hot-pressed silicon nitride ceramics with various sintering additives has been investigated. The weight gain of each specimens has shown in the range of 0.11 mg/$\textrm{cm}^2$ ~3.4 mg/$\textrm{cm}^2$ at 140$0^{\circ}C$ for 192 h and eleven compositions have shown good oxidation resistance with the weight gain below 0.5 mg/$\textrm{cm}^2$. The oxidation rate has been shown to obey the parabolic rate law and the oxidized surface has consisted of $\alpha$-cristobalite and M2Si2O7 or MSiO3 (M=rare earth or transition metals) phase. The oxidation rate of each specimens has related to the eutectic temperature between additive oxide and SiO2, and ionic radius of additive oxides, respectively. From the above results, it could be concluded that the oxidation behavior of hot pressed silicon nitride is dominated by the high temperature properties of grain boundary glassy phase and the high temperature properties of grain boundary glassy phase are affected by the ionic radius of additive oxides.

• 한국세라믹학회지
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• 제29권9호
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• pp.675-680
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• 1992

The purpose of this investigation was to study the stability of perovskite structure, the variation of electrical properties and a microstructure with varing amount of PbTiO3 additive in PZN-PT-BT system. The results are as follows: 1. The pyrochlore phase was reduced as the amount of PbTiO3 additive was increased and completely eliminated at 0.15PT in PZN-PT-BT system. 2. The aging rate was increased in proportion to tetragonality because the internal stress was increased in proportion to tetragonality. 3. On increasing the amount of PbTiO3 additive, the Curie temperature was increased in proportion to tetragonality. 4. As the amount of PT in the composition increase, the variation of dielectric constant was sharpened and the diffuseness of the transition decreased.

• 한국결정성장학회지
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• 제22권5호
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• pp.213-217
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• 2012

Carbon coils could be synthesized on nickel catalyst layer-deposited silicon oxide substrate using $C_2H_2$ and $H_2$ as source gases under thermal chemical vapor deposition system. By the incorporation of $SF_6$ additive in cyclic modulation manner, the dominant formation of the nanosized carbon coils could be achieved with maintaining the minimized sulfur additive amount. The geometry variation of the as-grown carbon coils, such as linear type, microsized coil type, wavelike nanosized coil type, and nanosized coil type, were investigated according to the different cyclic modulation manner of $SF_6$ flow. $SF_6$ gas incorporation develops the coil-type geometry. Furthermore, the higher flow rate of $SF_6$ gas increased the amount of the nanosized carbon coils. The slightly increased etching ability by $SF_6$ addition seems to be the cause for these results.

• 응용통계연구
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• 제9권1호
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• pp.75-89
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• 1996

본 논문에서는 하나의 이진공변량(binary covariate)을 갖는 가산위험모형(additive risk model)의 적합도를 검정하기 위한 검정법을 제안하였다. 제안된 검정법은 마팅게일잔차(martingale residual)에 기초한 Wei(1984)의 비례위험모형(proportional hazards model)의 적합도검정법을 가산위험모형으로 확장한 형태이다. 제안된 검정통계량의 점근성질을 유도하였고 실제자료에 적용하여 보았다.

• 한국경영과학회지
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• 제16권1호
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• pp.76-88
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• 1991

Stochastic convexity (concavity) of a stochastic process is a very useful concept for various stochastic optimization problems. In this study we first establish stochastic convexity of a certain class of Markov additive processes through probabilistic construction based on the sample path approach. A Markov additive process is abtained by integrating a functional of the underlying Markov process with respect to time, and its stochastic convexity can be utilized to provide efficient methods for optimal design or optimal operation schedule wide range of stochastic systems. We also clarify the conditions for stochastic monotonicity of the Markov process. From the result it is shown that stachstic convexity can be used for the analysis of probabilitic models based on birth and death processes, which have very wide applications area. Finally we demonstrate the validity and usefulness of the theoretical results by developing efficient methods for the optimal replacement scheduling based on the stochastic convexity property.

• 전기학회논문지P
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• 제57권2호
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• pp.198-201
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• 2008

We investigated the operating characteristics of the flux-lock type superconducting fault current limiter(SFCL) with the parallel connection between the primary and secondary windings which are connected with two superconducting units in series. The parallel connection for current level increase of the flux-lock type SFCL is necessary to apply the SFCL into the power system. The resistance generated in superconducting units was dependent upon the winding direction of the primary and the secondary coils, which can reduce the power burden. The resistance of the superconducting elements in the subtractive polarity winding is higher than that of the additive polarity winding. The fault current limiting effect of the subtractive polarity winding is better than that of the additive polarity winding. From this results, we confirmed that the power capacity of the flux-lock type SFCL could be increased by the parallel connection of the superconducting units.