• 한국토양비료학회지
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• 제45권4호
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• pp.593-601
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• 2012

Heavy metals and metalloids removal can be considered as one of the most important world challenges because of their toxicity and direct impact on human health. Many processes have been introduced but biological processes of remediation seem to offer the most suitable solution in terms of efficiency and low cost. Actinobacteria constitute one of the major microbial populations in soil, and this can be attributed to their adaptive morphological structure as well as their exceptional metabolic power. Among microbes, actinobacteria are morphologic intermediate between fungi and bacteria. Studies on microbial diversities in metal contaminated lands have shown that actinobacteria may constitute a dominantly active microbiota in addition to ${\alpha}$ Proteobacteria. Furthermore, isolation studies have shown metal removal mechanisms which are reminiscent of notable multiresistant strains, such as Cupriavidus metallidurans. Apart from members of genus Streptomyces, which produce more than 90% of commercialized antibiotics, and the nitrogen fixing Frankia, little attention has been given to other members of this phylum. This is because of difficult culture condition requirements and maintenance. In this review, we focused on specific isolation of actinobacteria and their potential applications in metal bioremediation and plant growth promotion.

• Advances in aircraft and spacecraft science
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• 제1권1호
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• pp.69-91
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• 2014

Numerical investigations are presented, which show that a back-flow flap can improve the dynamic stall characteristics of oscillating airfoils. The flap was able to weaken the stall vortex and therefore to reduce the peak in the pitching moment. This paper gives a brief insight into the method of function of a back-flow flap. Initial wind tunnel experiments were performed to define the structural requirements for a detailed experimental wind tunnel characterization. A structural integration concept and two different actuation mechanisms of a back-flow flap for a helicopter rotor blade are presented. First a piezoelectric actuation system was investigated, but the analytical model to estimate the performance showed that the displacement generated is too low to enable reliable operation. The seond actuation mechanism is based on magnetic forces to generate an impulse that initiates the opening of the flap. A concept based on two permanent magnets is further detailed and characterized, and this mechanism is shown to generate sufficient impulse for reliable operation in the wind tunnel.

• 한국시뮬레이션학회논문지
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• 제27권2호
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• pp.101-114
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• 2018

무인 비행체의 실시간 경로계획 생성 시 최적의 경로를 찾기 위한 다양한 연구가 진행되어 왔다. 본 논문에서는 진화알고리즘을 통한 무인비행체의 경로계획 생성을 수행하고, 이를 에이전트 기반 시뮬레이션 환경에서 구현 및 테스트가 가능함을 검증하였다. 이를 위해, Repast toolkit에 JGAP 패키지를 탑재하여 Java 기반의 유전 알고리즘 프로그래밍을 통한 무인 비행체의 경로 계획을 생성하였고, 해당 결과를 에이전트 기반으로 시뮬레이션을 수행하였다. 본 논문에서는 에이전트 기반 시뮬레이션 소프트웨어를 소프트웨어 공학 개발 생명주기에 맞춰 문서화하여 설계 및 구현되었으며, 에이전트 모델링 설계는 자동화, 적응성 및 에이전트 간의 상호 작용에 초점을 맞추었다. 또한, 시뮬레이션을 통해 에이전트 기반 환경에서 설계한 모델 및 시나리오를 검증하여 다수의 비행 에이전트에 내재된 동적 경로계획 알고리즘이 실시간으로 자율적인 경로 생성이 가능함을 증명하였다.

• Journal of Communications and Networks
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• 제7권3호
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• pp.337-352
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• 2005

In this paper, a fuzzy logic implementation of the random early detection (RED) mechanism [1] is presented. The main objective of the proposed fuzzy controller is to reduce the loss probability of the RED mechanism without any change in channel utilization. Based on previous studies, it is clear that the performance of RED algorithm is extremely related to the traffic load as well as to its parameters setting. Using fuzzy logic capabilities, we try to dynamically tune the loss probability of the RED gateway. To achieve this goal, a two-input-single-output fuzzy controller is used. To achieve a low packet loss probability, the proposed fuzzy controller is responsible to control the $max_{p}$ parameter of the RED gateway. The inputs of the proposed fuzzy controller are 1) the difference between average queue size and a target point, and 2) the difference between the estimated value of incoming data rate and the target link capacity. To evaluate the performance of the proposed fuzzy mechanism, several trials with file transfer protocol (FTP) and burst traffic were performed. In this study, the ns-2 simulator [2] has been used to generate the experimental data. All simulation results indicate that the proposed fuzzy mechanism out performs remarkably both the traditional RED and Adaptive RED (ARED) mechanisms [3]-[5].

• 아시안잔디학회지
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• 제25권2호
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• pp.125-132
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• 2011

잔디가 건조 스트레스를 받은 상태에서 잔디의 생리학적 메커니즘과 건조 상태에서 식물이 회복하는 생리학적 메커니즘을 보다 깊이 이해하고자 한다. 증산작용과 Stomatal Conductance의 상호 관계로 인한 광합성량의 변화, 식물 세포 내부의 변화, 삼투압 조절능력의 변화, 호르몬의 변화, 단백질 변성 등의 생리학적 반응들을 이해하고 건조 스트레스 상태에서 회복하는데 세포내부의 적응 과정, 뿌리의 반응과 같은 생리학적인 측면에 대해 이해하고 건조 스트레스 상태에서 엽록소가 흡수하고 반사하는 Spectral Reflectance의 변화를 이해하고자 한다. 하지만 건조스트레스로 인한 식물의 생리학적 메커니즘에는 아직 많은 의문점을 가지고 있으며 향 후 외부환경 스트레스에 의한 식물의 Self-defense 메커니즘을 더욱 깊게 이해하여 보다 수준 높은 관리기법들을 연구하는데 초점을 맞추어야 할 것이다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권12호
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• pp.4776-4798
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• 2015

The location selection of virtual machines in distributed cloud is difficult because of the physical resource distribution, allocation of multi-dimensional resources, and resource unit cost. In this study, we propose a multi-object virtual machine location selection algorithm (MOVMLSA) based on group information, doubly linked list structure and genetic algorithm. On the basis of the collaboration of multi-dimensional resources, a fitness function is designed using fuzzy logic control parameters, which can be used to optimize search space solutions. In the location selection process, an orderly information code based on group and resource information can be generated by adopting the memory mechanism of biological immune systems. This approach, along with the dominant elite strategy, enables the updating of the population. The tournament selection method is used to optimize the operator mechanisms of the single-point crossover and X-point mutation during the population selection. Such a method can be used to obtain an optimal solution for the rapid location selection of virtual machines. Experimental results show that the proposed algorithm is effective in reducing the number of used physical machines and in improving the resource utilization of physical machines. The algorithm improves the utilization degree of multi-dimensional resource synergy and reduces the comprehensive unit cost of resources.

• BMB Reports
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• 제43권9호
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• pp.629-634
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• 2010

Endotoxin including lipopolysaccharide (LPS) confers organ tolerance against subsequent challenge by ischemia and reperfusion (I/R) insult. The mechanisms underlying this powerful adaptive defense remain to be defined. Therefore, in this study we attempted to determine whether nitric oxide (NO) and its associated enzymes, inducible NOS (iNOS) and endothelial NOS (eNOS, a constitutive NOS), are associated with LPS-induced renal tolerance against I/R injury, using iNOS (iNOS knock-out) or eNOS (eNOS knock-out) gene-deleted mice. A systemic low dose of LPS pretreatment protected kidney against I/R injury. LPS treatment increased the activity and expression of iNOS, but not eNOS, in kidney tissue. LPS pretreatment in iNOS, but not eNOS, knock-out mice did not protect kidney against I/R injury. In conclusion, the kidney tolerance to I/R injury conferred by pretreatment with LPS is mediated by increased expression and activation of iNOS.

• 대한한방내과학회지
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• 제28권2호
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• pp.209-216
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• 2007

Background & Objective : The herbal medicine JGT has been used for the treatment of functional dyspepsia, generally categorized as a gastric disease. However, its effect and mechanism are not yet well known. Therefore, the effects of JGT on gastric emptying in rats was investigated to know its effectiveness and mechanism. Methods : Gastric emptying effect was measured by the number of glass beads expelled from the stomach within an hour after glass beads and test drugs were administered. In another series of experiments to evaluate the mechanisms of JGT under delayed conditions, the rats were treated with atropine sulfate Results : Intragastric administration of JGT significantly increased gastric emptying of glass beads Under the gastric emptying delayed with atropine sulfate, JGT insignificantly increased gastric emptying of glass beads. Conclusions : These suggest that JGT has a significant effect to stimulate gastric emptying. Results are indicative of JGT as an especially effective remedy for dysmotility-like functional dyspepsia with impaired reservoir function such as gastric adaptive relaxation.

• 인터넷정보학회논문지
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• 제8권4호
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• pp.137-147
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• 2007

웹 기반의 온라인 커뮤니티가 급속하게 증가함에 따라 사회적인 집단(커뮤니티)에서의 에이전트들은 안전하고 성공적인 상호거래를 위하여 서로의 신뢰도를 계산할 수 있는 형태의 믿음으로 알 수 있어야 한다. 본 논문은 온라인 커뮤니티에서 주어진 피드백으로 형성된 신뢰도의 계산적 모델을 제안한다. 신뢰도는 과거의 상호작용에 기반한 평가수치의 축적으로 정의할 수 있으며, 평균 신뢰도는 믿을 수 있는 값과 믿을 수 없는 값의 분포를 고려한 중심값으로 나타낸다. 온라인 커뮤니티에서의 명성, 신뢰도, 평균 신뢰도의 관계를 구체적인 예를 통하여 설명하며, 정의한 신뢰도 모델이 어떻게 온라인 커뮤니티에서 에이전트의 이성적인 거래를 가능하게 하는가를 보여준다.

• Genomics & Informatics
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• 제10권3호
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• pp.153-166
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• 2012

A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of pathogens and lead to primary innate immune activation against invaders, and G-protein coupled receptors (GPCRs), whose interaction with their cognate ligands activates heterotrimeric G proteins and regulates specific downstream effectors, including immuno-stimulating molecules. Once TLRs are activated, they lead to the expression of hundreds of genes together and bridge the arm of innate and adaptive immune responses. We characterized the gene expression profile of Toll-like receptor 4 (TLR4) in RAW 264.7 cells when it bound with its ligand, 2-keto-3-deoxyoctonate (KDO), the active part of lipopolysaccharide. In addition, to determine the network communications among the TLR, Janus kinase (JAK)/signal transducer and activator of transcription (STAT), and GPCR, we tested RAW 264.7 cells with KDO, interferon-${\beta}$, or cAMP analog 8-Br. The ligands were also administered as a pair of double and triple combinations.