• Title/Summary/Keyword: activity-based model

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Role of Stretch-Activated Channels in Stretch-Induced Changes of Electrical Activity in Rat Atrial Myocytes

  • Youm, Jae-Boum;Jo, Su-Hyun;Leem, Chae-Hun;Ho, Won-Kyung;Earm, Yung E.
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.1
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    • pp.33-41
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    • 2004
  • We developed a cardiac cell model to explain the phenomenon of mechano-electric feedback (MEF), based on the experimental data with rat atrial myocytes. It incorporated the activity of ion channels, pumps, exchangers, and changes of intracellular ion concentration. Changes in membrane excitability and $Ca^{2+}$ transients could then be calculated. In the model, the major ion channels responsible for the stretch-induced changes in electrical activity were the stretch-activated channels (SACs). The relationship between the extent of stretch and activation of SACs was formulated based on the experimental findings. Then, the effects of mechanical stretch on the electrical activity were reproduced. The shape of the action potential (AP) was significantly changed by stretch in the model simulation. The duration was decreased at initial fast phase of repolarization (AP duration at 20% repolarization level from 3.7 to 2.5 ms) and increased at late slow phase of repolarization (AP duration at 90% repolarization level from 62 to 178 ms). The resting potential was depolarized from -75 to -61 mV. This mathematical model of SACs may quantitatively predict changes in cardiomyocytes by mechanical stretch.

A Knowledge Based Physical Activity Evaluation Model Using Associative Classification Mining Approach (연관 분류 마이닝 기법을 활용한 지식기반 신체활동 평가 모델)

  • Son, Chang-Sik;Choi, Rock-Hyun;Kang, Won-Seok
    • IEMEK Journal of Embedded Systems and Applications
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    • v.13 no.4
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    • pp.215-223
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    • 2018
  • Recently, as interest of wearable devices has increased, commercially available smart wristbands and applications have been used as a tool for personal healthy management. However most previous studies have focused on evaluating the accuracy and reliability of the technical problems of wearable devices, especially step counts, walking distance, and energy consumption measured from the smart wristbands. In this study, we propose a physical activity evaluation model using classification rules, induced from the associative classification mining approach. These rules associated with five physical activities were generated by considering activities and walking times in target heart rate zones such as 'Out-of Zone', 'Fat Burn Zone', 'Cardio Zone', and 'Peak Zone'. In the experiment, we evaluated the prediction power of classification rules and verified its effectiveness by comparing classification accuracies between the proposed model and support vector machine.

Voice Activity Detection Based on Non-negative Matrix Factorization (비음수 행렬 인수분해 기반의 음성검출 알고리즘)

  • Kang, Sang-Ick;Chang, Joon-Hyuk
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.35 no.8C
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    • pp.661-666
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    • 2010
  • In this paper, we apply a likelihood ratio test (LRT) to a non-negative matrix factorization (NMF) based voice activity detection (VAD) to find optimal threshold. In our approach, the NMF based VAD is expressed as Euclidean distance between noise basis vector and input basis vector which are extracted through NMF. The optimal threshold each of noise environments depend on NMF results distribution in noise region which is estimated statistical model-based VAD. According to the experimental results, the proposed approach is found to be effective for statistical model-based VAD using LRT.

Introducing A Spatial-temporal Activity-Based Approach for Estimating Travel Demand at KTX Stations (KTX 정차 역의 교통수요 추정을 위한 시.공간 활동기반 분석기법 적용방안 연구)

  • Eom, Jin-Ki
    • Proceedings of the KSR Conference
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    • 2007.11a
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    • pp.734-743
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    • 2007
  • The KTX station is one of special generators that produce a lot of trips caused by special land use such as university, airport, and super shopping mall. Special generators need special attention in developing travel demand models since the standard trip generation and distribution model in the conventional four-step approach do not provide reliable estimates of their travel patterns. New modeling approach, activity-based model, considering travel behavior of person, seem to be more appropriate for those special generators. Thus, this study introduces a spatial-temporal activity-based approach and how activity-based approach can be applied to estimation of travel demand at KTX stations.

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Minimizing Project Quality Costs by Activity-Based Prevention (활동기준예방에 의한 프로젝트 품질코스트 최소화)

  • Kim, Jong-Yul;Kang, Chang-Wook;Hwang, In-Keuk
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.34 no.4
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    • pp.89-97
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    • 2011
  • Traditional quality control for manufacturing or service sector is not suitable for the quality control of a project as the project is one-time task constrained by time, cost, and quality. To meet the internal and external customers' requirements, quality costs approach to the project will be effective. Hence, we propose PONC (price of nonconformance) estimation procedure and a mathematical model, which are focused on activity-based prevention in the execution step and warranty step of EPLC (extended project life cycle). This procedure and model will help project manager develop preventive action plan for project quality costs minimization from nonconformance risk activities and PONC estimates information.

Analysis of Cost and Efficiency of a Medical Nursing Unit Using Time-Driven Activity-Based Costing (시간-동인활동기준원가계산(Time-Driven Activity-Based Costing)을 이용한 일 내과병동 간호단위 원가계산 및 효율성 분석)

  • Lim, Ji-Young;Kim, Mi-Ja;Park, Chang-Gi
    • Journal of Korean Academy of Nursing
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    • v.41 no.4
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    • pp.500-509
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    • 2011
  • Purpose: Time-driven activity-based costing was applied to analyze the nursing activity cost and efficiency of a medical unit. Methods: Data were collected at a medical unit of a general hospital. Nursing activities were measured using a nursing activities inventory and classified as 6 domains using Easley-Storfjell Instrument. Descriptive statistics were used to identify general characteristics of the unit, nursing activities and activity time, and stochastic frontier model was adopted to estimate true activity time. Results: The average efficiency of the medical unit using theoretical resource capacity was 77%, however the efficiency using practical resource capacity was 96%. According to these results, the portion of non-added value time was estimated 23% and 4% each. The sums of total nursing activity costs were estimated 109,860,977 won in traditional activity-based costing and 84,427,126 won in time-driven activity-based costing. The difference in the two cost calculating methods was 25,433,851 won. Conclusion: These results indicate that the time-driven activity-based costing provides useful and more realistic information about the efficiency of unit operation compared to traditional activity-based costing. So time-driven activity-based costing is recommended as a performance evaluation framework for nursing departments based on cost management.

Structural Characteristics that Influence on the Insecticidal Activity of 2-(n-Octyl)pseudothiourea Analogues against the Diamondback Moth (Plutella xylostella, L.)

  • Soung, Min-Gyu;Kil, Mun-Jae;Sung, Nack-Do
    • Bulletin of the Korean Chemical Society
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    • v.30 no.11
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    • pp.2749-2753
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    • 2009
  • Structural characteristics that influence on the insecticidal activity ($pI_{50}$) of 2-(n-octyl)isothiourea analogues (1-45) against the diamondback moth (Plutella xylostella, L.) based on three dimensional quantitative structure activity relationships (3D-QSARs) were discussed quantitatively using a comparative molecular field analysis (CoMFA) and a comparative molecular similarity indeces analysis (CoMSIA) methods. The statistical values of the CoMFA 2 model were better than those of the CoMSIA 1 model. The CoMFA 2 model was the optimized model with the correlativity (the training set: Ave. = 0.104 & PRESS = 0.613) and the predictability (the test set: Ave. = 0.086 & PRESS = 0.096). Insecticidal activities with the optimized CoMFA 2 model were dependent upon steric factors (79.4%) of $R_1-R_3$ substituents. From the analytical results of CoMFA contour maps, it is predicted that the R1 substituent of 1-45 which has a steric favor in a broad space, $R_2\;and\;R_3$ groups with a steric favor in a narrow space and a H-bond donor favor would have better the insecticidal activity.

Modeling of XPDL Meta-Model for Workflow Process Definition Interchange (워크플로우 프로세스 정의 교환을 위한 XPDL 메타모델의 모델링)

  • Kim, Jin-Sung;Yoo, Chun-Sik;Kim, Yong-Sung
    • Journal of KIISE:Software and Applications
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    • v.32 no.6
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    • pp.486-501
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    • 2005
  • XPDL is a XML-based language for process definition exchange that is proposed by WfMC. This paper propose a model which model XPDL document structure (Schema) using UML in order to define and to exchange workflow process, and make business flow understanding ease for inter-business cooperation. So, we define mapping rules in which map XPDL documents into UML class diagram and UML activity diagram. By these mapping rules, elements composing XPDL process meta-model are mapped into UML class diagram, and process activities are mapped into UML activity diagram. Also, we apply proposed mapping technique to model a workflow of (')Credit card state check system.(')

The Exploratory Research on Object Activity Service Evaluation Model(OA-SEM) - The Application of Retail Industry

  • Lee, Seung-Chang;Suh, Eung-Kyo;Park, Hoon-Sung
    • Journal of Distribution Science
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    • v.14 no.8
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    • pp.45-50
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    • 2016
  • Purpose - This study aimed to develop a new practical and universally applicable service quality model by improving the service quality measurement model proposed by many previous studies. Research design, data, and methodology - An in-depth analysis on what influences such service quality model had on the improvement effect of service quality, and Service Evaluation Model("SEM"), which was revised from the existing service quality measurement model, was developed. The model is divided into the two integrative categories: First, activity, that is the group of service-related activities. Next is item, the group of service-related objects. The level of service is evaluated for each category via survey questionnaire on service level evaluation. Based on the model, SEM has visibility by structuring the whole service industry. Results - For the application of the new service quality model, this study attempted to examine the appropriateness of the newly proposed service quality model by applying it to retail service field. Conclusions - As a result, the proposed service model would be a useful and applicable service quality measurement model required by many organizations. Service company can set up self check service levels. Through these results, they can look for the ways to provide better services to customers. Service users can ensure the objectivity of business plan based upon SEM.

A Proposal for the Design of Augmented Reality Reading Activity Application and Class Model Based On Nuri Curriculum (누리과정을 기반으로 한 증강현실 독후활동 애플리케이션 및 수업 모형 설계 제안)

  • Seo-Young Kim;Tae-Woo Kim;Kyung-Up Lee;Yu-Bin Joe;Jung-Yi Kim
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.1
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    • pp.355-360
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    • 2023
  • Recently, with the development of digital, children are exposed to a lot of media media. Reading activity decreases, making it difficult to acquire information from books or organize and remember acquired information. Since education with augmented reality increases children's participation and immersion in learning, we proposed a reading activity application with augmented reality technology to increase children's reading interest and creativity. In addition, based on the five nurturing processes, we designed a play-oriented reading activity for the application. In addition to the application suggestions, we designed a play-centered lesson model so that it can be used in actual lessons. In order to analyze the conceptual thinking framework according to the lesson model design, we visited an actual daycare center and conducted a class attended by an expert. Experts who participated were asked to fill out a pre-produced questionnaire to review the suitability of the reading activity class model and operation, and the feasibility was examined. Our lesson model design was based on limited book content, and due to ethical concerns, large-scale experiments with children could not be conducted, so the results of the study are not representative of the whole. However, it is significant that the possibility of running a new reading activity class based on the Nuri course has been examined and proposed.