• The Journal of Internal Korean Medicine
• /
• v.42 no.5
• /
• pp.1118-1130
• /
• 2021

The purpose of this study was to report the clinical effect of Korean medicine in a patient with anemia of chronic disease (ACD). The patient was treated with herbal medicine, acupuncture, and moxibustion in combination with Western medicine for around 4 weeks. Although the patient's hemoglobin concentration was maintained at a similar level, the other clinical symptoms of ACD (anorexia, xerostomia, dizziness, and general weakness) were improved after the treatment with Korean medicine. Therefore, Korean medicine treatment may be effective for improving the clinical symptoms of ACD.

• The Korea Journal of Herbology
• /
• v.33 no.3
• /
• pp.55-61
• /
• 2018

Objectives : Artemisia capillaris Thunberg (AC) and Artemisia iwayomogi Kitamura (AI) have been used without distinguishment since ancient times due to similar appearance. In this study, we compared the inhibitory effects of AC and AI on the expression of inflammatory cytokines induced by lipopolysaccharide (LPS) in murine macrophages. Methods : AC and AI were extracted by reflux with distilled water (DW) and 70% ethanol (EtOH). We investigated the inhibitory effects of AC and AI on the expression of nitric oxide (NO), inducible NO synthase (iNOS) and tumor necrosis $factor-{\alpha}$($TNF-{\alpha}$) induced by LPS in macrophages. Results : Firstly, yield of the samples was higher in order of Artemisia iwayomogi DW Extract (AID), Artemisia iwayomogi 70% EtOH Extract (AIE), Artemisia capillaris DW Extract (ACD) and Artemisia capillaris 70% EtOH Extract (ACE). All of the samples were not toxic in macrophages. The inhibitory effect of the samples on LPS-induced NO expression was stronger in the order of AIE, ACE, AID and ACD. The inhibitory effect of the samples on LPS-induced inducible iNOS expression was stronger in the order of AIE, ACE and AID. Effect of ACD was same with that of AID. In addition, inhibitory effect of the samples on LPS induced $TNF-{\alpha}$expression wes stronger in the order of AIE, ACE, AID and ACD. Conclusion: These results showed that AI would be more effective than AC and 70% EtOH would be more effective than DW as an extraction solvent in inflammatory diseases.

• Journal of the Korean Dietetic Association
• /
• v.29 no.4
• /
• pp.230-247
• /
• 2023

This study aimed to investigate the association between awareness of having a chronic disease with food habits and dietary quality among 320 male manufacturing workers in their 40s. Participants were categorized into groups. The first group comprised workers who were aware of having chronic diseases (ACD, n=160) and had been diagnosed with any one or more of the following major chronic diseases: Metabolic syndrome, hyperlipidemia, hypertension, obesity, and cardiovascular disease. The second group comprised those who had experienced none of the above diseases were classified as a group of people who were a ware of not having chronic diseases (ANCD, n=160). The mean age of the subjects was 44.2 years. The mean weight (P<0.001) and body mass index (BMI; P<0.01) were significantly higher in the ACD than in the ANCD group. The frequency of alcohol consumption and the number of current smokers were not significantly different between the two groups. Dietary attitudes were not significantly different between the two groups. The frequency of egg consumption was significantly higher in the ACD group (P<0.05). Picky eating, vegetable intake, checking nutrition labels, and healthy eating behavior were not significantly different between the two groups. The frequency of exercise was significantly lower in the ACD group compared to the ANCD group (P<0.05). The mean nutrition quotient (NQ) score was 51.9, with no significant difference between the two groups. Based on these results, the awareness of suffering from chronic diseases was not significantly related to dietary attitudes, food habits, and overall dietary quality among production workers. Therefore, there is a need to develop and implement nutrition education programs to inculcate an awareness of health status that can lead to dietary changes.

• Journal of Sasang Constitutional Medicine
• /
• v.27 no.2
• /
• pp.240-253
• /
• 2015

Objectives The aim of this study was to investigate the effects of GalGunSeungGi-Tang (GST) on allergic contact dermatitis (ACD) induced by 2,4-dintrochlorobenzone (DNCB) Methods In this study, The changes of body weight, ear weight, ear thickness, spleen weight, dorsum skin thickness, symptom score by eyesight, histological finding, proliferation rates of splenocyte in vitro and in vivo are investigated to check effects of GST. The mice are divided into four group; Normal (naive mice), Control (DW administered), GST-L (GST 500mg/Kg/day administered), GST-H (GST 1,000mg/Kg/day administered). Results GST inhibited weight of ear significantly (P < 0.05) and also thickness (P < 0.01). In addition, There are significant decrease in thickness of dorsum skin and proliferation rates of splenocyte in vivo in GST administered group. Finally, GST reduced symptom score and hyperkeratosis, hyperpigmentation, increase of granulocyte and parakeratosis in histological finding. Conclusions These results suggest that GST can decrease symptoms of ACD.

• Journal of Ocean Engineering and Technology
• /
• v.27 no.6
• /
• pp.73-80
• /
• 2013

The dynamic characteristics of west coast sand were investigated in order to evaluate the design properties of the offshore wind turbine foundations to be constructed in the West Sea. Torsional shear tests were performed at different confining pressures and densities on specimens constituted by the dry fluviation method. The strain-dependent shear modulus and damping curves were obtained, together with modulus degradation curves. The results show that the confining pressure is more influential on the dynamic characteristics of the sand than the density. It was also found that the dynamic curves from this study were similar to those proposed by others. The modulus degradation ratio $G/G_{1st}$ varies slightly at a small strain level, but increases significantly once beyond the intermediate strain level.

• Journal of Sasang Constitutional Medicine
• /
• v.26 no.2
• /
• pp.180-193
• /
• 2014

Objectives The present study was carried out to investigate effects of HBPDS on allergic contact dermatitis (ACD) induced by 2,4-Dinitro-1-fluorobenzene (DNFB) in mice. Methods In this experiment, effects of HBPDS on body weights, skin thicknesses, skin weights, histopathological changes, clinical aspects, erythema index, melanin index, production levels of cytokines in ACD mice were investigated. In addition, effects on proliferation rates, release of ${\beta}$-hexosaminidase and histamine were also investigated in vitro. Results & Conclusions 1) HBPDS inhibited enlargement of skin thickness and weight significantly (P < 0.05). 2) HBPDS treatment prevented spongiosis, edema and immune cell infiltrations. 3) Erythema, desquamation and keratosis were diminished by oral administration of HBPDS. 4) Production levels of TNF-alpha and IFN-gamma in serum were decreased by HBPDS treatment in vivo. 5) More than 200 ${\mu}g/ml$ of HBPDS treatment decreased ${\beta}$-hexosaminidase release and more than 400 ${\mu}g/ml$ of HBPDS treatment also decreased histamine release in vitro.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.27 no.4
• /
• pp.243-250
• /
• 2014

Objective : The purpose of this report is to know the effect of oriental medical treatments on acute allergic contact dermatitis with multiple nummular eczema. Methods : We treated a 34-years-old woman patient with acute allergic contact dermatitis on face and multiple nummular eczema on both arm, right ankle and left inguinal region by Korean medicine. After Korean medical treatment for 42 days in hospital, we measured the decrease of exudation and pruritis as well as recovery of skin damages. We recorded pictures of changes on symptoms. Results & Conclusion : The symptoms of ACD and nummular eczema were significantly improved except scars. Exudation and pruritis were disappeared and skin damages were almost recovered until discharge from hospital. After 20 days we could confirm the symptoms were clearly disappeared. Thus Korean medical treatments are effective on ACD and nummular eczema.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.35 no.5
• /
• pp.543-548
• /
• 2006

After allergic contact dermatitis (ACD) elicited by application of 1 mL of 2.5% 1-chloro-2,4-dinitrochloro-benzene (DNCB) onto dorsal skin, Sprague Dawley male rats fed Scutellaria baicalensis water extract were observed to investigate the mitigative effect of Scutellaria baicalensis water extract on ACD. The Scutellaria baicalensis water extract (100 mg/kg/day) was daily administered to rats suffered from ACD. Concentrations of TBARS in plasma and liver were increased in rats with ACD. The concentrations of TBARS in liver were significantly decreased in Scutellaria baicalensis-fed group (SBFG) compared to control group (CG), but not in plasma. Liver SOD activity was significantly increased in SBFG compared to that of normal group and CG. Serum Ig E level was significantly increased in CG compared to normal group, while that of SBFG was significantly decreased. The epidermal thickness of CG was significantly increased compared to that of normal group, while that of SBFG was significantly decreased compared to that of CG. These results indicated that the Scutellaria baicalensis water extract administration was effective for antioxidative activity in liver, serum Ig E level and epidermal thickness of rats with ACD.

• Korean Journal of Food Science and Technology
• /
• v.44 no.2
• /
• pp.240-246
• /
• 2012

This study evaluated the efficacy of strong acidic electrolyzed water (SAcEW), low alkaline electrolyzed water (LAlEW) and aqueous chlorine dioxide (ACD) for reducing pathogenic bacteria($Escherichia$ $coli$, $Bacillus$ $cereus$, $Salmonella$ Typhimurium, $Stapylococcus$ $aureus$) on Chinese cabbage. Artificially inoculated Chinese cabbage was immersed for 1, 5 and 10 min with TW, NaClO, EW and ACD. Generally, leaves showed more effective reduction than stems. Regarding the inhibitory effect, ACD treatment showed the highest effects rather than other treatments. When Chinese cabbage was immersed for 3 min in sterilized water, it was reduced to a minimum of 1.33 log CFU/g at LAlEW and a maximum of 4.70 log CFU/g at ACD. Compared to NaClO, ACD and LAlEW which showed a reduction of 3.2 log CFU/g ($Sal.$ Typhimurium) and 2.7 log CFU/g($B.$ $cereus$), respectively. Furthermore, the others had similar inhibitory effects compared to NaClO.

• Clinical and Experimental Pediatrics
• /
• v.46 no.11
• /
• pp.1095-1100
• /
• 2003

Purpose : Children with acute colonic diverticulitis(ACD), can be misdiagnosed with acute appendicitis. Methods : We reviewed 15 cases of ACD during five years, from January 1998 to June 2002 retrospectively. Results : Most patients(80%) with ACD in children presented with right lower quadrant pain. The primary diagnosis on admission was mostly acute appendicitis(87%), and all ACD in children occurred in the right colon. Fourteen patients were managed by conservative treatment including antibiotics. A follow-up study was performed in 15 patients. There were symptomatic recurrences in two patients, but no significant complication was noted. The frequency of ACD was 11.7 per 1000 acute appendicitis. Conclusion : ACD in children can mostly be cured by conservative treatment. It is prudent to choose the management through the diagnostic work up, including abdominal sonography and computed tomography, because there was no significant difference of clinical findings between ACD and acute appendicitis.