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Case Report of Hypohidrotic Ectodermal Dysplasia with Anotondia (무치증과 저한성 외배엽 이형성증 보고)

  • Park, Kye-Ra;Lee, Kyung-Eun;Suh, Bong-Jik
    • Journal of Oral Medicine and Pain
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    • v.31 no.2
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    • pp.121-126
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    • 2006
  • Hypohidrotic ectodermal dysplasia refers to a group of disorders with the following common features : thin, sparse or absent hair, missing or peg-shaped teeth and inability to sweat adequately. Both the primary and secondary dentition are affected. Teeth may be absent (anodontia) or reduced in number (oligodontia) and abnormally shaped. In case, A 5-year-old man presented with hypohidrosis and dry skin. He had no teeth in mouth. We report a case of hypohidrotic ectodermal dysplasia with anodontia.

Establishment of Short-Term Teratogenicity Study for Detecting Developmental Toxicity Induced by Gamma Radiation (방사선의 발생독성 검색을 위한 단기 최기형성 시험법의 확립)

  • 김종춘;김성호;신동호;신진영;김세라;이해준;박승춘;조성기;이윤실
    • Toxicological Research
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    • v.20 no.2
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    • pp.117-122
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    • 2004
  • The present study was carried out to establish a short-term teratogenicity study for detecting developmental toxic potential induced by gamma radiation in ICR mice. Pregnant mice were exposed at dose levels of 0, 0.5, 1, 2, or 4 Gy on gestational day 8.5. All dams were subjected to caesarean section on gestational day 10.5 and their embryos were examined for growth, differentiation, and morphological abnormalities. An increase in the number of resorption was found at 4 Gy in a dose-dependent manner. Dose-dependent decreases in the developmental score of yolk sac circulation and olfactory system at above 1 Gy, in the number of somite pairs and developmental score of allantois, optic system, and maxillary process at above 2 Gy, and in the all growth and developmental parameters examined at 4 Gy were found. Various types of morphological abnormalities were seen at dose levels of 0.5 Gy or greater. Characteristic malformations induced by gamma radiation were abnormal axial rotation, hematoma, craniofacial hypoplasia, open neuropore, shortened prosencephalon, kinked somites, irregular somites, swelling, hydropericardium, absent branchial bar, and absent limb bud. Morphological alterations such as hematoma, craniofacial hypoplasia, open neuropore, and kinked somites were noted even in the lowest dose (0.5 Gy). These results indicated that the short-term teratogenicity study established in this study can be a useful tool for not only detecting the developmental toxic potential induced by gamma radiation, but also screening radio-protective agents in ICR mice.

The role of visual and verbal information on the functionality of shapewear in female consumers' online purchase decisions

  • Shin, Eonyou;Zhang, Ling;Hwang, Chanmi;Baytar, Fatma
    • The Research Journal of the Costume Culture
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    • v.27 no.6
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    • pp.539-552
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    • 2019
  • The purpose of the current study was to examine the role of information on shapewear's functionality in consumers' purchase decisions in an online shopping context. Through two steps of stimulus development process, four mock websites were developed to conduct a main study. In the main study, a 2 (visual information: absent vs. present images of the shapewear's functionality) x 2 (verbal information: absent vs. present descriptions of the shapewear's functionality) between-subject factorial design was employed to examine the impact of visual and verbal information regarding the functionality of shapewear on the consumer decision-making process (i.e., attitudes and purchase intentions). The results showed that verbal information about how shapewear reduces the size of specific body parts (i.e., waist, abdomen, hips, and thighs) were effective in increasing perceived attractiveness in an online context, which increased attitudes and purchase intentions. In addition, attitudes toward the shapewear mediated the effects of expected physical attractiveness on purchase intentions. The results of this study provided empirical support for the importance of expected physical attractiveness in consumers' online purchase decision on shapewear and useful managerial implications for enhancing the effectiveness of online shapewear presentations by including descriptions of the functionality of shapewear in decreasing the size of body parts.

Roles of ginsenosides in inflammasome activation

  • Yi, Young-Su
    • Journal of Ginseng Research
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    • v.43 no.2
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    • pp.172-178
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    • 2019
  • Inflammation is an innate immune response that protects the body from pathogens, toxins, and other dangers and is initiated by recognizing pathogen-associated molecular patterns or danger-associated molecular patterns by pattern-recognition receptors expressing on or in immune cells. Intracellular pattern-recognition receptors, including nucleotide-binding oligomerization domain-like receptors (NLRs), absent in melanoma 2, and cysteine aspartate-specific protease (caspase)-4/5/11 recognize various pathogen-associated molecular patterns and danger-associated molecular patterns and assemble protein complexes called "inflammasomes." These complexes induce inflammatory responses by activating a downstream effector, caspase-1, leading to gasdermin D-mediated pyroptosis and the secretion of proinflammatory cytokines, such as interleukin $(IL)-1{\beta}$ and IL-18. Ginsenosides are natural steroid glycosides and triterpene saponins found exclusively in the plant genus Panax. Various ginsenosides have been identified, and their abilities to regulate inflammatory responses have been evaluated. These studies have suggested a link between ginsenosides and inflammasome activation in inflammatory responses. Some types of ginsenosides, including Rh1, Rg3, Rb1, compound K, chikusetsu saponin IVa, Rg5, and Rg1, have been clearly demonstrated to inhibit inflammatory responses by suppressing the activation of various inflammasomes, including the NLRP3, NLRP1, and absent in melanoma 2 inflammasomes. Ginsenosides have also been shown to inhibit caspase-1 and to decrease the expression of $IL-1{\beta}$ and IL-18. Given this body of evidence, the functional relationship between ginsenosides and inflammasome activation provides new insight into the understanding of the molecular mechanisms of ginsenoside-mediated antiinflammatory actions. This relationship also has applications regarding the development of antiinflammatory remedies by ginsenoside-mediated targeting of inflammasomes, which could be used to prevent and treat inflammatory diseases.

First reliable record of a stingray, Hemitrygon izuensis (Nishida and Nakaya, 1988) (Chondrichthyes: Dasyatidae) from Korea (한국산 색가오리과(Dasyatidae) 어류 1미기록종, Hemitrygon izuensis (Nishida and Nakaya, 1988))

  • JANG, Seo-Ha;KIM, Jin-Koo
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.57 no.3
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    • pp.205-213
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    • 2021
  • Two specimens of Hemitrygon izuensis (395.8-471.5 mm in disc width), belonging to the family Dasyatidae (Myliobatiformes), were collected from the waters off north-eastern Jeju-do Island in June 2016 and Pohang in August 2019. This species was characterized by having no spots on dorsal side of disc, white ventral tail fold and short preorbital snout length (15.6-18.3% of disc width). This species is similar to H. akajei and H. sinensis reported in Korea, but differs in small denticles on mid-line of dorsal surface of disc (absent in H. izuensis vs. present in H. akajei and H. sinensis), the length of ventral tail fold (28.1-31.0% in H. izuensis vs. 48.0-48.6% in H. akajei vs. 45.0% in H. sinensis), color of ventral tail fold (white in H. izuensis vs. black in H. akajei and H. sinensis) and small tubercles on the posterior part of tail (absent in H. izuensis vs. present in H. akajei and H. sinensis). We suggest a Korean name for H. izuensis as "I-ju-gal-saeg-ga-o-li" following Kim et al. (2019).

A Study on the Stress and the Health Status of Newspaper Employees (신문사 근로자들의 스트레스와 건강상태에 관한 연구)

  • Kim, Jin-Hee
    • Korean Journal of Occupational Health Nursing
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    • v.10 no.1
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    • pp.41-54
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    • 2001
  • This study was designed to assess the relationship between occupational stress and health status in a study group of 197 workers employed in four newspaper publishing companies, using a self-adminstrative questionnaire. The types of occupation of them were reporters(79), clerical workers(54), and engineers (64). The studies on workers' health have been focused mainly on the physical, chemical, and biological diseases in our country. Therefore, the study of mental health, especially of occupational stress, is to be carried out. I consider stress as a factor having an effect on the health status of the newspaper employees, who have been well known to have high stress due to time pressures. I expect that this research will be helpful not only for understanding of health status by occupation, but also for making clear the issues that have been raised continuously from the previous researches. The results of this study are as follows; 1. The mean values of stress by occupation were statistically significant; the reporters had the highest stress symptom scores, and the engineers had the lowest levels of stress. The mean values of stress symptoms were higher in the workers who had long working hours. 2. The health status by occupation showed significant differences in gastrointestinal systems and in depression. The clerical workers were healthier than the engineers in gastrointestinal systems, and the reporters were more depressed than the engineers in depression. 3. The health status by the general characteristics, there was a statistical significance as for a gender, marital status, and absenteeism in the gastrointestinal systems. The men, the married, and the workers who had not been absent were more healthy. Only absenteeism had an effect on the problems in optical-dermal systems and in oro-fecal systems. Gender, marital status, absenteeism, and working hours were related with health status : the men. the married, the workers who had not been absent, and the workers who had longer working hours were more healthy. In mental stability, gender had a significant effect : the men were more healthy than the women. In general condition, the men, the older, the married, and the workers who had not been absent were more healthy. 4. Stress level had an effect on the health status in the respiratory systems, optical-dermal systems, oro-fecal system, depression, mental stability, general condition, and health condition. The workers who perceived more stress had more problems in their health status. 5. In the results of the multiple regression analyses, age in the respiratory systems, absenteeism in the optical-dermal systems, occupation and absenteeism in the gastrointestinal systems and in the oro-fecal systems, gender in depression and in mental stability, gender, age, absenteeism, and working hours in the general condition, absenteeism in the health condition had an effect on the health status of the workers.

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A comparative study of borehole size and tool effect on dispersion curves (시추공경과 공내검층기가 분산곡선에 미치는 영향에 대한 비교 연구)

  • Zhao, Weijun;Kim, Jong-Man;Kim, Yeong-Hwa
    • Geophysics and Geophysical Exploration
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    • v.12 no.1
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    • pp.154-162
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    • 2009
  • Sonic wave dispersion characteristics are one of the most important targets of study, particularly in estimating shear wave velocity from borehole sonic logging. We have tested dispersion characteristics using monopole and dipole sources. Theoretical dispersion curves were computed for tool-absent and tool-included models having the same physical properties but different diameters (including ${\Phi}520mm$, ${\Phi}150mm$, and ${\Phi}76mm$). Comparisons were made between boreholes of different sizes and between tool-absent and tool-included models. Between the tool-included and the tool-absent boreholes, a close similarity in dispersion curve shape was revealed for the monopole source, and a significant difference was shown for the dipole source. However, for the cut-off frequency, particularly in the engineering boreholes (${\Phi}76mm$ and ${\Phi}50mm$), a significant difference was observed for signals from the monopole source, but approximately the same cut-off frequencies were found with the dipole source. This indicates the need of careful choice of source frequency in monopole-source sonic logging, particularly in an engineering borehole. The results of numerical experiments show that cut-off frequency is exponentially proportional to the inverse of borehole radius, irrespective of the mode type and the presence of a tool, and that the cut-off frequencies for each borehole environment could be expressed as an exponential function, rather than the inversely proportional relationship between the cut-off frequency and the borehole radius that was previously generally recognised. From the direct comparison of dispersion curves, the effects on the dispersion characteristics of borehole size and the presence of the tool can be revealed more clearly than in previous studies, which presented the dispersion curve and/or characteristics for each borehole environment separately.

The Role of Interstitial Cells of Cajal in Congenital Megacolons and Idiopathic Megacolons (선천성 거대결장 및 특발성 거대결장에서 카할 세포의 역할)

  • Yoo, Soo-Young;Koh, Yong-Taek;Han, Ai-Ri;Jung, Soon-Hee;Eom, Min-Seob;Kim, Il-Ho
    • Advances in pediatric surgery
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    • v.8 no.2
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    • pp.113-118
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    • 2002
  • The etiology of several motility disorders, including persistent megacolon after definitive surgery for Hirschsprung's disease, meconium ileus which is not associated with cystic fibrosis and idiopathic megacolon, is still unclear. Interstitial cells of Cajal (ICC) are thought to modulate gut motility as gastrointestinal pace maker cells. The aim of this study was to evaluate the role of ICC in the bowel walls of the patients (n=15) who had variable motility disorders. The ICC were identified by immunohistochemical staining using an anti-C-Kit antibody and the results were compared with control specimens (n=2). The control group (G1) showed evenly distributed ICC in their bowel walls. The second group (G2, n=5) who had normal bowel movements after Duhamel procedures and the third group (G3, n=4) who had persistent megacolon after Duhamel procedures showed absent or scarcely distributed ICC in their aganglionic bowels. The ICC were immunohistochemical staining using an anti-C-Kit antibody and the results were compared with control specimens (n=2). The control group (G1) showed evenly distributed ICC in their bowel walls. The second group (G2, n=5) who had normal bowel movements after Duhamel procedures and the third group (G3, n=4) who had persistent megacolon after Duhamel procedures showed absent or scarcely distributed ICC in their aganglionic bowels. Whereas ICC were evenly distributed in the ganglionic bowels of G2, they were not seen or scarecely distributed in the ganglionic bowels of G3. Two patients (G4) who suffered from idiopathic megacolon showed absence or decrease of ICC in spite of presence of ganglion cells in their colons. Four neonates (G5) who underwent ileostomy because of meconium obstruction showed absent or markedly decreased ICC in the the colon at the time of ileostomy and the distribution of ICC was changed to a normal pattern at the time of ileostomy closure between 39-104 days of age and their bowel motility were restored after that. The results suggest that lack of ICC caused reduce motility in the ganglionic colons and it may be responsible for the development of various motility disorders. Delayed maturity of ICC may also playa role in the meconium obstruction of neinates.

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Impact of Largemouth Bass (Micropterus salmoides) on the Population of Korean Native Fish, Crucian Carp (Carassius auratus) (배스가 국내 호소에 서식하는 붕어 개체군에 미치는 영향)

  • Lee, Jin-Woong;Kim, Jeong-Hui;Park, Sang-Hyeon;Choi, Kee-Ryong;Lee, Hae-Jin;Yoon, Ju-Duk;Jang, Min-Ho
    • Korean Journal of Environmental Biology
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    • v.31 no.4
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    • pp.370-375
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    • 2013
  • Exotic species in aquatic ecosystem generate various problems domestically as well as globally. Largemouth bass (Micropterus salmoides) which is a well-known exotic species globally, acts as a substantial disturbance factor on the native fish communities in Korea due to the high predation pressure and hence designated as a ecologically harmful species by Ministry of Environment. In this study, we investigated the impact of largemouth bass on Korean native fish population, crucian carp (Carassius auratus), to identify responses of the prey fish. Two fish species were collected at seven reservoirs distributed at the Nakdong River catchment area, and changes in length-frequency and length-weight relationship (LWR) were analysed depending on existence of large-mouth bass. At bass absent sites, ratio of under age 1 year individuals were small, and over age two years were dominant. Conversely, normal length-frequency distribution pattern was identified at bass absent sites. The LWR of crucian carp (fish smaller than total length of 160 mm were only considered as it is frequently consumed by bass predation) was different depending upon bass existence. The value of parameter b at bass absent reservoirs was 2.909, which was smaller than that of bass present reservoirs, 3.100. Our results imply that crucian carp at bass present reservoirs presented a different strategy to survive from predation by bass, through relatively rapid growth. We propose that other native species might have similar growth strategies like crucian carp.

First Record of the Antrorse Spined Gurnard Pterygotrigla multiocellata (Triglidae, Scorpaeniformes) from Korea

  • Kim, Joon Sang;Song, Choon Bok
    • Fisheries and Aquatic Sciences
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    • v.18 no.3
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    • pp.283-286
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    • 2015
  • This is the first report of Pterygotrigla multiocellata from the family Triglidae, collected in Korea. The specimen (314 mm in standard length) was caught in a gill net in the coastal waters of Jeju Island on 11 February 2010. This species is characterized by the following morphological traits: head large and triangular, bony plates absent along the base of the second dorsal fin, antrorse rostral spine long, and cleithral spine long. We suggest a new Korean name, "Gin-ppul-mit-seong-dae" for P. multiocellata.