• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.3917-3925
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• 2012

Background: The relationship between postmenopausal hormone therapy (HT) and invasive breast cancer has been extensively investigated, but that with breast carcinoma in situ (BCIS) has received relatively little attention. The aim of our present study was to review and summarize the evidence provided by longitudinal studies on the association between postmenopausal HT use and BCIS risk. Methods: A comprehensive literature search for articles published up to May 2012 was performed. Prior to performing a meta-analysis, the studies were evaluated for publication bias and heterogeneity. Relative risk (RR) or odds ratio (OR) values were calculated using 14 reports (8 case-control studies and 6 cohort studies), published between 1986 and 2012. Results: There was evidence of an association between ever postmenopausal estrogen use and BCIS based on a random-effects model (RR = 1.25, 95% confidence interval (CI) = 1.01, 1.55). However, we found no strong evidence of an association between ever postmenopausal estrogen combined with progesterone use and BCIS using a randomeffects model (RR = 1.55, 95% CI = 0.95, 2.51). Furthermore, our analysis showed a strong association between "> 5 years duration" of estrogen or estrogen combined with progesterone use and BCIS. Furthermore, current use of any HT is associated with increased risk of BCIS in cohort studies. Additional well-designed large studies are now required to validate this association in different populations.

• Journal of Hospice and Palliative Care
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• 제18권2호
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• pp.136-147
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• 2015

목적: 본 연구는 통합적 완화 돌봄 중재연구가 말기 암환자의 삶의 질에 미치는 효과 크기를 분석하기 위한 메타분석 연구이다. 방법: 말기 환자와 통합적 완화 돌봄 중재 및 연구 설계를 나타내는 용어들을 병합하여 PubMed, Cochrane Library CENTRAL, LWW (Ovid), CINAHL 및 국내 데이터 베이스에서 검색하였다. 논문의 질평가는 RCT 연구인 경우 RoB 도구를 사용하였으며, Non-RCT 연구인 경우는 RoBANS를 사용하였다. 중재의 효과크기는 Stata 10 프로그램으로 메타분석 하였다. 결과: 8편의 연구가 최종선정 되었으며, 총 대상자의 수는 356명이었다. 통합적 완화 돌봄 중재는 평균 6.5주, 5.6 세션으로 이루어졌으며, 한 세션당 평균 47.8분이 소요되었다. 효과는 동질성 및 하위그룹 분석을 실시하였다. 통합적 완화 돌봄 중재의 효과는 삶의 질(ES=1.83, P=0.018, $l^2=92%$), 영적 안녕(ES=0.78, P=0.040, $l^2=0$), 우울(ES=0.86, P<0.001, $l^2=32$) 및 불안(ES=0.69, P=0.041, $l^2=71.1$)에서 효과가 있었다. 그러나 말기암환자의 통증(ES=0.365, P=0.230, $l^2=69.8$)에는 효과가 없었다. 결론: 이상의 결과로 통합적 완화 돌봄 중재는 비록 통증은 완화시키지는 못했으나 우울과 불안을 감소시키고 영적 안녕과 삶의 질을 높이는 것으로 나타나, 통합적 완화 돌봄 중재는 말기암환자의 사회심리영적 차원의 삶의 질을 증진시킬 수 있다고 본다.

• 전자공학회논문지 IE
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• 제47권1호
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• pp.22-33
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• 2010

본 연구의 목적은 전문대학 공학계열 학생들의 학업성취와 자기조절학습전략의 향상을 위하여 성찰저널을 수업에 적용하고 그 효과성을 검증하는 데 있다. 본 연구에서 사용한 성찰저널은 학생들의 학업성취와 자기조절학습전략, 특히 메타인지와 비판적 사고 등을 향상시키기 위한 인지도구로서 (1) 5점 Likert 척도로 된 자기평가, (2) 수업에세이, (3) 동료와의 대화, (4) 교수님과의 대화 등으로 구성되어 있는 '구조화된 성찰저널'이다. 이러한 성찰저널의 효과를 검증하기 위하여 2009년 8월 24일부터 10월 16일까지 총 8주 동안 공학계열 1학년 94명(이론반 42명, 실험실습반 52명)을 연구반(성찰저널 적용 수업)과 비교반(성찰저널을 적용하지 않는 반)으로 구분하여 수업을 진행하고, 이러한 수업 유형에 따라 사전과 사후의 학업성취도와 자기조절학습전략의 차이가 있는지를 검증하기 위해 공분산 분석(analysis of covariance)을 실시하였다. 연구 결과, 성찰저널이 공학계열 신입생들의 학업성취도와 자기조절학습전략을 향상시키는 데 긍정적인 효과가 있음이 증명되었다.

• 대순사상논총
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• 제24_1권
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• pp.315-349
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• 2014

This paper was carried out to bring the researches on Cultivation Practice of Daesoonjinrihoe which have been at a standstill after analyzing the directions of studies on Cultivation Practice and diagnosing its problems, in addition to that, the paper was also conducted in a way of discussing the research directions in the future. This work enables scholars who have interests in Daesoon Thoughts to easily comprehend over the length and breadth of Cultivation Practice of Daesoonjinrihoe as well as help them understand what level of researches regarding Cultivation Practice has been demanded. Furthermore, this paper will be a step-stone for scholars to ponder how and on what perspective they approach a wide variety of studies on Daesoon Thoughts. The problems reflected on the previous researches on Cultivation Practice are summarized as follows: first, except a few researches in general, problem recognition, research target, style, method, and content are not diverged from the frame defined by Jang Byeong-Gil, who set it up in Daesoon Religion and Thought (Daesoon Jonggyo Sasang) in 1989. Proliferating overlapped researches without developing problem awareness is of great concern. And such researching climate has gradually set in. Secondly, there are numerous researches intending to reveal the researcher's forceful attitude implying faith. Thirdly, most of the previous researches neglect to focus on defining the range of researches. Fourthly, when defining concepts, more thorough insight is needed. Lastly, the researches on analysing symbols and attempting signification analysis are relatively few, only to find many errors. To solve these problems, this paper suggests to develop theories which back up Cultivation Practice by researching on the fields of theory of mind-nature(心性), theory of mind-qi(心氣), theory of pain, Religious Ethics, viewpoint of God/gods, and psychology. Secondly, all the symbols and meanings of elements shown in Cultivation Practice need analyzing more elaborately sophisticatedly and more in-depth. In order to fulfil this goal, by adapting the recent trends of historical studies, it is essential to attempt to engraft Cultivation Practice of Daesoonjinrihoe on cultural phenomena, to analyze thick layers of meanings beneath its surface, to interpret differently, utilizing various perspectives such as focusing on the gender problems, and to extract true meanings out of Cultivation Practice by analyzing everyday events which can occur in real cultivation practices. Thirdly, the terms and concepts regarding Cultivation Practice base the principle themselves. Fourthly, by utilizing methodology of comparative studies on religions, the comparative researches on cultivation practice of different religious traditions are also needed. Lastly, the history of aspects on Cultivation Practice such as transition of mantras, processes which have been conducted through proprieties of prayer and training should be collected and classified. In this context, this work is very important since it helps understand the aspects of transition of originality and characteristics in Cultivation Practice of Daesoonjinrihoe according to passage of time.

• Asian-Australasian Journal of Animal Sciences
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• 제30권12호
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• pp.1684-1688
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• 2017

Objective: From a review of published information on genetic association studies, a meta-analysis was conducted to determine the influence of the genes ${\kappa}-casein$ (CSN3) and ${\beta}-lactoglobulin$ (LGB) on milk yield traits in Holstein, Jersey, Brown Swiss, and Fleckvieh. Methods: The GLIMMIX procedure was used to analyze milk production and percentage of protein and fat in milk. Models included the main effects and all their possible two-way interactions; not estimable effects and non-significant (p>0.05) two-way interactions were dropped from the models. The three traits analyzed used Poisson distribution and a log link function and were determined with the Interactive Data Analysis of SAS software. Least square means and multiple mean comparisons were obtained and performed for significant main effects and their interactions (p<0.0255). Results: Interaction of breed by gene showed that Holstein and Fleckvieh were the breeds on which CSN3 ($6.01%{\pm}0.19%$ and $5.98%{\pm}0.22%$), and LGB ($6.02%{\pm}0.19%$ and $5.70%{\pm}0.22%$) have the greatest influence. Interaction of breed by genotype nested in the analyzed gene indicated that Holstein and Jersey showed greater influence of the CSN3 AA genotype, $6.04%{\pm}0.22%$ and $5.59%{\pm}0.31%$ than the other genotypes, while LGB AA genotype had the largest influence on the traits analyzed, $6.05%{\pm}0.20%$ and $5.60%{\pm}0.19%$, respectively. Furthermore, interaction of type of statistical model by genotype nested in the analyzed gene indicated that CSN3 and LGB genes had similar behavior, maintaining a difference of more than 7% across analyzed genotypes. These results could indicate that both Holstein and Jersey have had lower substitution allele effect in selection programs that include CSN3 and LGB genes than Brown Swiss and Fleckvieh. Conclusion: Breed determined which genotypes had the greatest association with analyzed traits. The mixed model based in Bayesian or Ridge Regression was the best alternative to analyze CSN3 and LGB gene effects on milk yield and protein and fat percentages.

• 한방안이비인후피부과학회지
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• 제34권3호
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• pp.27-54
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• 2021

Objectives : This review was conducted to validate the effectiveness and safety of herbal medicine combined with conventional therapy for rosacea. Methods : Randomized controlled trials(RCTs) reporting the effects of herbal medicine treatment on rosacea were searched through eight electronic databases from 2016 to March 17, 2020. This study collection and data extraction were performed by two independent reviews. The Cochrane risk-of-bias tool was used for the evaluation of the risk of bias in all included RCTs. Mean differences(MD) and Risk ratio(RR) of 95% Confidence intervals(Cls) were calculated and data synthesis was conducted using Review Manager(RevMan, ver.5.4) Results : Eighteen RCTs were included and all trials compared the combined therapy of herbal medicine with conventional western therapy to conventional therapy alone. The effective rate of the combination of herbal medicine with western medicine(RR 1.20, 95% CI : 1.13-1.28, p<0.00001, I²=0%), the effective rate of the combination of herbal medicine with laser-based therapy(RR 1.12, 95% CI : 1.04-1.21, p=0.004, I²=18%) and the effective rate of the combination treatment group using herbal medicine, western medicine and external drugs were all statistically higher that of the control group(RR 1.19, 95% CI : 1.11-1.28, p<0.00001, I²=0%). The score of non transient erythema(MD -0.36, 95% CI : -1.01 0.29, p=0.27, I²=93%), flushing(MD -0.69, 95% CI : -0.97, 0.41, p<0.00001, I²=32%), papules or pustules(MD 0.10, 95% CI : -0.15, 0.35 p=0.44, I²=0%) were also seen in the herbal medicine and western medicine combination group. The overall risk of bias of the included studies was some concerns. No serious adverse effects were observed. Conclusions : This review found the safety and effectiveness of the combined therapy of herbal medicine with conventional western therapy for rosacea.

• 감성과학
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• 제14권4호
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• pp.627-636
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• 2011

본 연구는 단순 입력 기반 유니모달 인터랙션의 한계를 극복하고 단순 입력 방식이 아닌 멀티모달 기반 사용자의 행위, 의도, 및 집중도를 활용하여 실감적이고 몰입도를 향상시키는 인터랙션 시스템을 제안하는데 그 목적이 있다. 본 연구의 선행연구에서 기존 문헌연구를 토대로 메타분석방법을 활용하여 인터랙션을 위한 3차원 동작 인식 기술의 정확도를 분석하여 최종적인 센서 기반 인터랙션 방법이 선정되었고, 직관적 제스쳐 인터랙션 요소를 추출하여 본 시스템에 반영하였다. 또한 생리반응을 이용한 집중력 판단 기술을 개발하여 사용자 의도를 판단하는 연구를 진행하였다. 본 연구에서 제안하는 시스템은 3부분으로 나눌 수 있다. 선행연구에서 선정된 인터랙션 요소들을 적용하여 가속도(Accelator) 센서와 연성(Flexible) 센서를 활용하여 손 동작을 인식하는 시스템을 구현하였고, 동공 인터랙션을 통한 안경형 시선 추적기를 구현하여 인터랙션이 가능하게 하였으며, 심혈관 반응과 피부 온열 반응을 측정하여 사용자의 의도를 반영한 시스템을 최종 구현하였다. 실감형 디지털 엔터테인먼트 플랫폼 기술 개발을 위한 기초 연구로서 활용이 가능할 것으로 판단된다.

• 대한간호학회지
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• 제30권2호
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• pp.319-330
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• 2000

This study is aimed at analyzing the trend of research on the use of exercise in nursing research, through suggesting directions for future research and implementation of the various exercise therapies. Research studies were taken from dissertations and theses selected from the Academic Society Journals of nursing science, Journals from universities, medical and nursing schools, research institutes in various universities, the Central Journal of Medicine, and the New Medical Journal. The research published between 1970 and 1997 in Korea were analyzed, 51 research were selected. The research are analyzed according to: published time, source of the research, research design, subjects, sample size, dependant variables, exercise therapy, and effect of exercise therapy. The results were as follows: 1. Research on exercise therapy increased rapidly in the 1990's. At this time, 88.2% of research was published. 2. Research areas included: 54.9% non- degree research, 27.5% Doctoral theses, and 17.6% Master's theses. 3. The experimental design included: 66.7% non- equivalent control group pre-test/ post-test design and 29.4% one group pre-test/post- test design. 4. Out of the Subjects: 52.9% were patients with various health problems, and 47.1% were healthy individuals. 5. Sample size included: 52.9% with above 31 subjects, 11.8% with 11~15 and 26~30. 6. Exercise therapy was analyzed by type, intensity, frequency, duration, and period. 1) The Types: Aerobic exercise at 60.8% was the most common, active exercise for muscle strengthening and building made up 21.6%. 2) Exercise with 40~65% intensity comprised 25.5%, 70~85% with 7.8%, and no description of the intensity was 66.7%. 3) Frequency of 3~5 per week was the most common at 78.4%. 4) Duration: 15~60 minutes was the most common length of time at 76.5%. 5) Periods: More than 5 weeks at 82.3% were the most common in their categories. 7. Dependant variables: Psychological response was measured as a dependant variable in 92.2%, Cardio-pulmonary function 88.2%, Body Composition was 86.3%, Physical Response was 60.8%, Lipid Metabolism was 58.8%, Physical Strength was 49.0%, Glucose Metabolism was 25.5%, Activities of Daily Living was 17.6% and others added to be 3.9%. 8. The effect of Exercise Therapy was categorized into 'positive', 'partially positive', and 'no effect' according to dependant variables: Having a positive effect - Glucose Metabolism (93.3%), Physical Response (85.0%), Activities of Daily Living (81.8%), Psychological Response (71.6%), Lipid Metabolism (67.6%), Cardio- pulmonary Function (63.6%), Physical Strength (68.1%), and Body Composition (56.4%). The following suggestions can be made on the above findings: 1. Research findings on Exercise Therapy as a Nursing Intervention need to be described by their elements of type, intensity, frequency, duration and period. 2. Toproperly study the positive effects of Exercise Therapy, there needs to be ⑴ appropriate research design, ⑵ selection criteria for the subjects ⑶ contents of exercise prescription to individuals or groups ⑷ measurement criterion for the dependent variables. 3. Meta-analysis on exercise therapy also needs to be done to analyze and integrate the various results.

• 비교교육연구
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• 제18권4호
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• pp.141-162
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• 2008

우리 주변에서 접할 수 있는 대부분의 이러닝 프로그램들은 강의법을 주된 교수방법으로 활용하고 있다. 이러닝 환경에서 강의법은 가장 효과적이지 못한 교수방법이라는 메타분석 연구결과 및 학습자의 능동적 참여만이 이러닝 프로그램의 성공을 보장할 수 있다는 학자들의 주장은 강의법 위주의 이러닝 프로그램의 학습효과에 의문을 제기하게 한다. 결국, 이러닝 프로그램의 질적 수준과 그 효과는 어떠한 페다고지를 적용하느냐에 따라 결정된다고 할 수 있다. 이 연구는 설계 연구(design research)를 통해 질적 개선을 추구하고 있는 미국의 이러닝 프로그램들이 어떠한 심리적 특성들을 공통적으로 반영하고 있는 지에 대한 분석을 통해 국내 이러닝 프로그램들의 개선을 위한 시사점을 제시하고자 하였다. 분석된 미국의 이러닝 프로그램들은 공통적으로 구성주의 교육철학의 배경을 가지고 반성적 사고, 협력적 상호작용 공간, 지식 구성, 맥락적 행위, 외적 표상의 활용 등의 심리적 특성들을 강조하고 있었다. 즉, 경험주의 학습, 상황학습, 협력학습, 복합표상 학습 등은 국내 이러닝 프로그램의 개선을 위해서 고려해야 할 학습원칙들일 것이다.

• 지능정보연구
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• 제22권1호
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• pp.1-18
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• 2016

최근 가용한 텍스트 데이터 자원이 증가함에 따라 방대한 텍스트 분석을 통해 새로운 가치를 창출하고자 하는 수요가 증가하고 있다. 특히 뉴스, 민원, 블로그, SNS 등을 통해 유통되는 글로부터 다양한 이슈를 발굴해내고 이들 이슈의 추이를 분석하는 이슈 트래킹에 대한 연구가 활발하게 이루어지고 있다. 전통적인 이슈 트래킹은 토픽 모델링을 통해 오랜 기간에 걸쳐 지속된 주요 이슈를 발굴한 후, 각 이슈를 구성하는 문서 수의 세부 기간별 분포를 분석하는 방식으로 이루어진다. 하지만 전통적 이슈 트래킹은 각 이슈를 구성하는 내용이 전체 기간에 걸쳐 변화 없이 유지된다는 가정 하에 수행되기 때문에, 다양한 세부 이슈가 서로 영향을 주며 생성, 병합, 분화, 소멸하는 이슈의 동적 변이과정을 나타내지 못한다. 또한 전체 기간에 걸쳐 지속적으로 출현한 키워드만이 이슈 키워드로 도출되기 때문에, 핵실험, 이산가족 등 세부 기간의 분석에서는 매우 상이한 맥락으로 파악되는 구체적인 이슈가 오랜 기간의 분석에서는 북한이라는 큰 이슈에 함몰되어 가려지는 현상이 발생할 수 있다. 본 연구에서는 이러한 한계를 극복하기 위해 각 세부 기간의 문서에 대한 독립적인 분석을 통해 세부 기간별 주요 이슈를 도출한 후, 각 이슈의 유사도에 기반하여 이슈 흐름도를 도출하고자 한다. 또한 각 문서의 카테고리 정보를 활용하여 카테고리간의 이슈 전이 패턴을 분석하고자 한다. 본 논문에서는 총 53,739건의 신문 기사에 제안 방법론을 적용한 실험을 수행하였으며, 이를 통해 전통적인 이슈 트래킹을 통해 발굴한 주요 이슈의 세부 기간별 구성 내용을 살펴볼 수 있을 뿐 아니라, 특정 이슈의 선행 이슈와 후행 이슈를 파악할 수 있음을 확인하였다. 또한 카테고리간 분석을 통해 단방향 전이와 양방향 전이의 흥미로운 패턴을 발견하였다.