• Title/Summary/Keyword: a meta analysis

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Full-Endoscopic versus Minimally Invasive Lumbar Interbody Fusion for Lumbar Degenerative Diseases : A Systematic Review and Meta-Analysis

  • Son, Seong;Yoo, Byung Rhae;Lee, Sang Gu;Kim, Woo Kyung;Jung, Jong Myung
    • Journal of Korean Neurosurgical Society
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    • v.65 no.4
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    • pp.539-548
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    • 2022
  • Objective : Although full-endoscopic lumbar interbody fusion (Endo-LIF) has been tried as the latest alternative technique to minimally invasive transforaminal lumbar interobody fusion (MIS-TLIF) since mid-2010, the evidence is still lacking. We compared the clinical outcome and safety of Endo-LIF to MIS-TLIF for lumbar degenerative disease. Methods : We systematically searched electronic databases, including PubMed, EMBASE, and Cochrane Library to find literature comparing Endo-LIF to MIS-TLIF. The results retrieved were last updated on December 11, 2020. The perioperative outcome included the operation time, blood loss, complication, and hospital stay. The clinical outcomes included Visual analog scale (VAS) of low back pain and leg pain and Oswestry disability index (ODI), and the radiological outcome included pseudoarthosis rate with 12-month minimum follow-up. Results : Four retrospective observational studies and one prospective observational study comprising 423 patients (183 Endo-LIF and 241 MIS-TLIF) were included, and the pooled data analysis revealed low heterogeneity between studies in our review. Baseline characteristics including age and sex were not different between the two groups. Operation time was significantly longer in Endo-LIF (mean difference [MD], 23.220 minutes; 95% confidence interval [CI], 10.669-35.771; p=0.001). However, Endo-LIF resulted in less perioperative blood loss (MD, -144.710 mL; 95% CI, 247.941-41.478; p=0.023). Although VAS back pain at final (MD, -0.120; p=0.586), leg pain within 2 weeks (MD, 0.005; p=0.293), VAS leg pain at final (MD, 0.099; p=0.099), ODI at final (MD, 0.141; p=0.093) were not different, VAS back pain within 2 weeks was more favorable in the Endo-LIF (MD, -1.538; 95% CI, -2.044 to -1.032; p<0.001). On the other hand, no statistically significant group difference in complication rate (relative risk [RR], 0.709; p=0.774), hospital stay (MD, -2.399; p=0.151), and pseudoarthrosis rate (RR, 1.284; p=0.736) were found. Conclusion : Relative to MIS-TLIF, immediate outcomes were favorable in Endo-LIF in terms of blood loss and immediate VAS back pain, although complication rate, mid-term clinical outcomes, and fusion rate were not different. However, the challenges for Endo-LIF include longer operation time which means a difficult learning curve and limited surgical indication which means patient selection bias. Larger-scale, well-designed study with long-term follow-up and randomized controlled trials are needed to confirm and update the results of this systematic review.

Assessment of Soil Contamination and Hydrogeochemistry for Drinking Water Sites in Korea (국내 먹는샘물 개발지역의 토양 오염 평가 및 수리지구화학적 특성)

  • 이두호;전효택
    • Journal of the Korean Society of Groundwater Environment
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    • v.4 no.1
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    • pp.41-53
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    • 1997
  • Geochemical data of soil and water samples were presented in order to assess the environmental impart for drinking water sites. Microscopic observation of rock samples and physical and chemical analysis of soil and water samples were undertaken. The geology of study areas are classified into three groups such as granitic rocks, meta-sedimentary rocks and sedimentary rocks. Enrichment of heavy metals derived from those rocks is not found in this study areas. Soils were analyzed for Cu, Pb, Zn, Cd and Cr using AAS extracted by HNO$_3$+HClO$_4$ and 0.1 N HCl. Heavy metal concentrations in soils are within the range of those in uncontaminated soils. In comparison of metal contents extracted by 0.1 N HCl and HNO$_3$+HC1O$_4$, less than 10% of the heavy metals are present in the exchangeable fraction. In particular, an pollution index has been proposed to assess the degree of soil contamination. Pollution index in soils are between 0.03 and 0.47 therefore, soils are not polluted with heavy metals. Deep groundwaters within granitic rocks have been evolved into Na$\^$+/-HCO$_3$$\^$-/ type, whereas other deep groundwaters evolved into Ca$\^$2+/-HCO$_3$$\^$-/ type. The predominance of Na$\^$+/ over Ca$\^$2+/ in deep groundwaters within granitic rocks is a result of dissolution of plagioclase, but for sedimentary and meta-sedimentary rocks, dissolution of calcite is a dominant factor for their hydrogeochemistry. The pH, conductivity and contents of the most dissolved ions in the water increase with depth. Shallow groundwaters, however, are highly susceptible to pollution owing to agricultural activities, considering the fact that high contents of nitrate, chloride and potassium, and high K/Na ratio are observed in some shallow groundwaters. In a thermodynamic approach, most natural water samples are plotted within the stability fields of kaolinite and smectite. Therefore, microcline and other feldspars will alter to form clay minerals, such as kaolinite and smectite. From the modelling for water-rock interactions based on mass balance equation, models accord well with behavior of the ions and results of thermodynamic studies are derived.

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A study of the clinical effects of various bone graft materials (다양한 골 이식재의 임상 효과에 대한 고찰)

  • Lee, Seung-Bum;Yon, Je-Young;Chae, Gyung-Joon;Jung, Ui-Won;Kim, Chang-Sung;Lee, Yong-Geun;Cho, Kyoo-Sung;Chai, Jung-Kiu;Kim, Chong-Kwan;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.37 no.4
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    • pp.719-732
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    • 2007
  • Purpose: Various bone graft materials are being used for periodontal tissue regeneration. Th materials are being developed continuously for ideal clinical effects. Therefore, it is necessary to identify the clinical characteristics of each bone graft material through comparing the various bone graft materials statistically and in doing so, proposing a more efficient bone graft material. In this study, the following results were attained through comparing the clinical effects among the bone graft materials, using the statistical method based on the clinical studies published at the department of periodontology of Yonsei hospital. Materials and Method: 6 selected studies of department of Periodontology at Yonsei University Hospital were based on clinical study of bone grafting in intrabony defects. It was compared the clinical parameters among the 6 clinical studies, using the statistical META analysis. Result: When comparing the probing depth reduction, there was a relatively great amount of decease when using the xenograft, Anorganic Bovine Derived Hydroxapatite Bone Matrix/Cell Binding Peptide(ABM/P-15: PepGen $P-15^{(R)}$) and the autogenous bone and absorbable membrane, d, 1-alctide/glycolide copolymer(GC: $Biomesh^{(R)}$). The allogfrafts showed a relatively low decrease in the probing depth and clinical attachment change. It also showed a slight decrease in the bone probing depth. The allografts showed various results according to different bone graft materials. When comparing the ABM/P-15 and bovine bone $powder(BBP^{(R)})$, ABM/P-15 showed a relatively high clinical attachment level and the bovine bone powder showed a relatively high clinical attachment level. The probing depth change and gingival recession change showed a lower value than the mean value between the two bone graft materials. The synthetic bone showed a relatively high decrease in clinical attachment level and periodontal probing depth change. There was a relatively larger amount of gingival recession when using Bioactive Glass(BG) but a relatively low bone regeneration effect was seen. Conclusion: Good restorative results of the periodontal tissue can be attained by applying the various bone graft materials being used today after identifying the accurate clinical effects.

Analysis of Posting Preferences and Prediction of Update Probability on Blogs (블로그에서 포스팅 성향 분석과 갱신 가능성 예측)

  • Lee, Bum-Suk;Hwang, Byung-Yeon
    • Journal of KIISE:Databases
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    • v.37 no.5
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    • pp.258-266
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    • 2010
  • In this paper, we introduce a novel method to predict next update of blogs. The number of RSS feeds registered on meta-blogs is on the order of several million. Checking for updates is very time consuming and imposes a heavy burden on network resources. Since blog search engine has limited resources, there is a fix number of blogs that it can visit on a day. Nevertheless we need to maximize chances of getting new data, and the proposed method which predicts update probability on blogs could bring better chances for it. Also this work is important to avoid distributed denial-of-service attack for the owners of blogs. Furthermore, for the internet as whole this work is important, too, because our approach could minimize traffic. In this study, we assumed that there is a specific pattern to when a blogger is actively posting, in terms of days of the week and, more specifically, hours of the day. We analyzed 15,119 blogs to determine a blogger's posting preference. This paper proposes a method to predict the update probability based on a blogger's posting history and preferred days of the week. We applied proposed method to 12,115 blogs to check the precision of our predictions. The evaluation shows that the model has a precision of 0.5 for over 93.06% of the blogs examined.

Positional Accuracy Analysis According to the Exterior Orientation Parameters of a Low-Cost Drone (저가형 드론의 외부표정요소에 따른 위치결정 정확도 분석)

  • Kim, Doo Pyo;Lee, Jae One
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.2
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    • pp.291-298
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    • 2022
  • Recently developed drones are inexpensive and very convenient to operate. As a result, the production and utilization of spatial information using drones are increasing. However, most drones acquire images with a low-cost global navigation satellite system (GNSS) and an inertial measurement unit (IMU). Accordingly, the accuracy of the initial location and rotation angle elements of the image is low. In addition, because these drones are small and light, they can be greatly affected by wind, making it difficult to maintain a certain overlap, which degrades the positioning accuracy. Therefore, in this study, images are taken at different times in order to analyze the positioning accuracy according to changes in certain exterior orientation parameters. To do this, image processing was performed with Pix4D Mapper and the accuracy of the results was analyzed. In order to analyze the variation of the accuracy according to the exterior orientation parameters in detail, the exterior orientation parameters of the first processing result were used as meta-data for the second processing. Subsequently, the amount of change in the exterior orientation parameters was analyzed by in a strip-by-strip manner. As a result, it was proved that the changes of the Omega and Phi values among the rotation elements were related to a decrease in the height accuracy, while changes in Kappa were linked to the horizontal accuracy.

Systematic Review of Effects of Nasal Continuous Positive Airway Pressure on Apnea of Preterm Infants (미숙아 무호흡을 위한 비강 지속적 양압환기법 효과에 대한 체계적 고찰)

  • Kim, Eun-Joo
    • Child Health Nursing Research
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    • v.20 no.3
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    • pp.225-235
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    • 2014
  • Purpose: The purpose of this study was to analysis the effects of nasal Continuous Postive Airway Pressure (nCPAP) for preterm infants using systematic review and meta-analysis. Methods: Thirteen peer-reviewed journals including preterm infants and apnea and nCPAP published between 1973 and 2013 were included. Effect size and statistics of homogeneity were done using STATA 10.0. Results: The design for 9 studies was Randomized Control Trial. In most of studies the pressure of nCPAP was set to 4-6 cm$H_2O$. The effect size of 5 studies for the effect on apnea rate using nCPAP compared to nasal Intermittent Positive Pressure Ventilator (nIPPV) showed that the Standardized Mean Difference (SMD) was -0.11 and was not significantly different (Z=0.41, p=.680). But the difference in nCPAP for nasal Synchronizes Intermittent Positive Pressure Ventilator (nSIPPV) (subgroup) was significant (SMD=-.44). The effect size of 7 studies on effect for ventilator weaning of using nCPAP compared to nIPPV showed the Risk Ratio (RR) as 1.60 and was not significantly different (Z=1.12, p=.268). But the difference between nCPAP and nSIPPV (subgroup) was significant (RR=3.94). Conclusion: The results indicate a need for an advanced care system and suggest continuous studies of apnea in preterm infants.

An Exploratory Study of Key Success Factors in Public R&D Institutions' Business Supporting Service -Focused on Ceramic Hidden Champion Project- (국가연구개발기관 기술사업화 종합지원사업 성공요인에 관한 탐색적 연구 -세라믹히든챔피언사업을 중심으로-)

  • Kwon, Kyung-Sup;Kim, Byeong-Jin;Ha, Kyu-Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.7 no.1
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    • pp.225-232
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    • 2012
  • The purpose of this study is to explore the necessity of technology commercialization aiding service from government-supported R&D institutions and find key success factors for market performance improvement of business ventures and SMEs. For this aim, we researched relevant theories and KICET(Korea Institute of Ceramic Engineering and Technology)'s "Ceramic Hidden Champion Supporting Project. As government-supported R&D institutions, KICET is not only providing its original main service which is technology advising and development, but also providing a full range of technology commercialization aiding service for business ventures including diagnosis, strategy planning, capital procurement, overseas marketing activity. Qualitative analysis based on relevant theories and meta-analysis framework suggest that such expansion of services is desirable for government-supported R&D institutions to increase market performance of business ventures and SMEs. To lead this business to success, we should develop effective management system and incentive system for external supporting companies and client companies. Also, coordination between team member's activities and budget procurement issue should be solved for further performance creation.

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Understanding the Current Status of Research on Traditional Korean Medicine Treatment for the People with Disability and Suggestions for Further Research: Scoping Review (장애인 한의치료 연구의 현황 파악과 후속 연구에 대한 제언을 위한 Scoping Review)

  • Kwon, Miri;Lee, Jungmin;Kang, Doyoung;Jeon, Hyonjun;Kim, Suna;Kim, Mihyun;Lee, Shinhee;Jun, Hyungsun;Kang, Heeseol;Cheong, Moonjoo;Leem, Jungtae
    • Journal of Korean Medicine Rehabilitation
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    • v.32 no.1
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    • pp.89-106
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    • 2022
  • Objectives In this study, a scoping review was conducted to inform decision-making related to traditional Korean medicine for people with disabilities in the future. Methods Seven databases were searched to find previous studies on traditional Korean medicine for people with disabilities. Studies published until August 2021 were considered. Using the methodology of scoping review, research on traditional Korean medicine for people with disabilities was reviewed with the following steps: 1) drawing research questions, 2) searching for related studies, 3) selecting studies, 4) extracting data, and 5) analyzing and reporting results. Results Out of 2,072 studies, 7 research papers and 10 reports were finally selected. The research papers included 5 cases studies, 1 survey study, and 1 chart review. Most studies used herbal medicine and acupuncture treatment, but the reports on the interventions were not detailed. The reports included policy studies, project performance guidelines, and project results reports, and most of the evaluation indicators tended to be standardized. Conclusions This study reviewed the literature on traditional Korean medicine for people with disabilities. It presents future directions for clinical research on traditional Korean medicine for people with disabilities and can be used to inform healthcare policies and clinical practice. In the future, quantitative research such as clinical trials, meta-analysis, and health insurance big data analysis is needed to understand the current status and effects of traditional Korean medicine for people with disabilities. In addition, qualitative research is necessary to identify unmet demands of traditional Korean medicine for people with disabilities.

Comparative Analysis of Body Dysmorphic Disorder and Depressive Disorder between Health and Non-Health related Majors (보건계열과 비보건계열 학생의 신체이형장애와 자가우울에 대한 비교분석)

  • Oh, Na-Rae;Jeong, Seon-A;Jeong, Mi-Ae
    • The Journal of the Korea Contents Association
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    • v.13 no.3
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    • pp.211-217
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    • 2013
  • A body dysmorphic disorder refers to a state that individuals whose external appearance is normal consider their appearance to be meta-morphosed, or think there's something wrong with it, or view a trifle deficiency as severely disfigured. The purpose of this study was to examine the body dysmorphic disorder and depression of health-related and health-unrelated majors in an effort to compare the two groups. And it's also meant to investigate the relationship between body dysmorphic disorder and depression. The subjects in this study were 400 students at K college located in Gangwon Province. Out of them, the major of the 200 students belonged to the health science track, and that of the 200 students didn't. After a self-administered survey was conducted, the answer sheets from 319 respondents were analyzed. As a result, there appeared no differences between the health-related majors and the health-unrelated majors in body dysmorphic disorder. Although there might be various factors to concern body dysmorphic disorder, both groups found themselves to suffer from more depression when they had a severer body dysmorphic disorder, and their body dysmorphic disorder exerted a statistically significant influence on their self-rated depression. Therefore the careful management of body dysmorphic disorder was required, and it's especially needed to make research in that of health-related majors. At the same time, more detailed clinical research efforts should be directed into body dysmorphic disorder and self-rated depression.

A Theory of Intermediality and its Application in Peter Greenaway's (상호매체성의 이론과 그 적용 - 피터 그리너웨이의 <프로스페로의 서재>를 중심으로)

  • PARK, Ki-Hyun
    • Cross-Cultural Studies
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    • v.19
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    • pp.39-77
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    • 2010
  • The cinema of Peter Greenaway has consistently engaged questions of the relationship between the arts and particularly the relations of image and writing to cinema. When different types of images are correlated and merged with each other on the borders of painting, photography, film, video and computer animation, the interrelationships of the distinct elements cause a shift in the notion of the whole image. This analysis proposes to articulate the complex relationship between the 'interartial' dimension and the 'intermedial' dimension in Peter Greenaway's film, (1991). If the interartiality is interested in the interaction between various arts, including the transition from one to another, the intermediality articulates the same type of relationship between two or more media. The interactional relationship is the same on both sides; on the contrary, the relationship between art and media does not show the same symmetry. All art is based on one or more media - the media is a condition existence of art - but no art can't be reduced to the status of media. This suggests that if the interartiality always involves the intermediality, this proposal may not be reversed. First, we analyse a self-conscious investigation into digital art and technology. Prosospero's Books can be read as a daring visual essay that self-consciously investigates the technical and philosophical functions of letters, books, images, animated paintings, digital arts, and the other magical illusions, which have been modern or will be post-modern media to represent the world. Greenaway uses both conventional film techniques and the resources of high-definition television to layer image upon image, superimposing a second or third frame within his frame. Greenaway uses the frame-within-frame as the cinematic equivalent of Shakespeare's paly-within-play : it offer him the possibility to analyse the work of art/artist/spectator relationship. Secondly, we analyse the relationship between the written word, oral word and the books. Like the written word, the oral word changes into a visual image: The linguistic richness and nuances of Shakeaspeare's characters turn into the powerful and authoritative, but monotone, voices of Gielgud-Prospero, who speaks the Shakespearean lines aloud, shaping the characters so powerfully through his worlds that they are conjured before us. Specially each book is placed over the frame of the play's action, only partially covering the image, so that it gives virtually every frame at least two space-time orientations. Thirdly, we try to show how Peter Greenaway uses pictorial references in order to illustrate the context of the Renaissance as well as pictorial techniques and language in order to question the nature of artistic representation. For exemple, The storm is visualised through reference to Botticelli's : the storm of papers swirling around the library is constructed to look like a facsimili copy of Michelangelo's Laurentiana Library in Florence. Greenaway's modern mannerism consists in imposing his own aesthetic vision and his questioning of art beyond the play's meta-theatricality: in other words, Shakespeare''s text has been adapted without being betrayed.