A study of the clinical effects of various bone graft materials

다양한 골 이식재의 임상 효과에 대한 고찰

  • Lee, Seung-Bum (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Yon, Je-Young (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Chae, Gyung-Joon (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Jung, Ui-Won (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Kim, Chang-Sung (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Lee, Yong-Geun (Department of Research, Institute of Dental Biometerials and Bioengineering, Yonsei University College of Dentistry) ;
  • Cho, Kyoo-Sung (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Chai, Jung-Kiu (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Kim, Chong-Kwan (Department of Periodontology, Yonsei University College of Dentistry) ;
  • Choi, Seong-Ho (Department of Periodontology, Yonsei University College of Dentistry)
  • 이승범 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 연제영 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 채경준 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 정의원 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 김창성 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 이용근 (연세대학교 치과대학 치과생체재료학교실) ;
  • 조규성 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 채중규 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 김종관 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 최성호 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소)
  • Published : 2007.12.31

Abstract

Purpose: Various bone graft materials are being used for periodontal tissue regeneration. Th materials are being developed continuously for ideal clinical effects. Therefore, it is necessary to identify the clinical characteristics of each bone graft material through comparing the various bone graft materials statistically and in doing so, proposing a more efficient bone graft material. In this study, the following results were attained through comparing the clinical effects among the bone graft materials, using the statistical method based on the clinical studies published at the department of periodontology of Yonsei hospital. Materials and Method: 6 selected studies of department of Periodontology at Yonsei University Hospital were based on clinical study of bone grafting in intrabony defects. It was compared the clinical parameters among the 6 clinical studies, using the statistical META analysis. Result: When comparing the probing depth reduction, there was a relatively great amount of decease when using the xenograft, Anorganic Bovine Derived Hydroxapatite Bone Matrix/Cell Binding Peptide(ABM/P-15: PepGen $P-15^{(R)}$) and the autogenous bone and absorbable membrane, d, 1-alctide/glycolide copolymer(GC: $Biomesh^{(R)}$). The allogfrafts showed a relatively low decrease in the probing depth and clinical attachment change. It also showed a slight decrease in the bone probing depth. The allografts showed various results according to different bone graft materials. When comparing the ABM/P-15 and bovine bone $powder(BBP^{(R)})$, ABM/P-15 showed a relatively high clinical attachment level and the bovine bone powder showed a relatively high clinical attachment level. The probing depth change and gingival recession change showed a lower value than the mean value between the two bone graft materials. The synthetic bone showed a relatively high decrease in clinical attachment level and periodontal probing depth change. There was a relatively larger amount of gingival recession when using Bioactive Glass(BG) but a relatively low bone regeneration effect was seen. Conclusion: Good restorative results of the periodontal tissue can be attained by applying the various bone graft materials being used today after identifying the accurate clinical effects.

Keywords

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