• 제목/요약/키워드: YoungChu

검색결과 773건 처리시간 0.03초

Preparation of Gold Nanoisland Arrays from Layer-by-Layer Assembled Nanoparticle Multilayer Films

  • Choi, Hyung-Y.;Guerrero, Michael S.;Aquino, Michael;Kwon, Chu-Hee;Shon, Young-Seok
    • Bulletin of the Korean Chemical Society
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    • 제31권2호
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    • pp.291-297
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    • 2010
  • This article introduces a facile nanoparticle self-assembly/annealing method for the preparation of nanoisland films. First, nanoparticle-polymer multilayer films are prepared with layer-by-layer assembly. Nanoparticle multilayer films are then annealed at $~500^{\circ}C$ in air to evaporate organic matters from the films. During the annealing process, the nanoparticles on the solid surface undergo nucleation and coalescence, resulting in the formation of nanostructured gold island arrays. By controlling the overall thickness (number of layers) of nanoparticle multilayer films, nanoisland films with various island density and different average sizes are obtained. The surface property of gold nanoisland films is further controlled by the self-assembly of alkanethiols, which results in an increased surface hydrophobicity of the films. The structure and characteristics of these nanoisland film arrays are found to be quite comparable to those of nanoisland films prepared by vacuum evaporation method. However, this self-assembly/annealing protocol is simple and requires only common laboratory supplies and equipment for the entire preparation process.

팔정산(八正散) 약침(藥鍼)이 글리세롤로 유발된 흰쥐의 급성 신부전에 미치는 영향 (The Effect of Paljeong-San Pharmacopuncture Treatment on Glycerol-Induced Acute Renal Failure in Rats)

  • 이소영;김민호;윤여충;조수인;임세현
    • 혜화의학회지
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    • 제21권1호
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    • pp.163-174
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    • 2012
  • Objective: The primary objective this study was to evaluate the effect of Paljeong-san (PJS) pharmacopuncture treatment on against the glycerol-induced acute renal failure in rats. Methods: Glycerol injection decreased GFR (glomerular filtration rate) and increased urine volume, serum creatinine, BUN level, urine albumine secretion and fractional excretion of Na+, K+. PJS was selected in the basis of invigorating kidney which can eliminate pathogens. Rats were treated with PJS pharmacopuncture on Shin-shu (BL23) and Chon-chu (ST25) point for 3 days, followed by 50% concentration of glycerol injection ($5m{\ell}/kg$ body weight). Results: After the 3 days treatment period, Paljeong-san (PJS) pharmacopuncture treatment improved renal function. In addition, Glycerol injection increased lipid peroxidation, and decreased Na-K-ATPase in renal cortex and which were prevented by PJS treatment. Conclusion: This study suggests that Paljeong-san (PJS) pharmacopuncture treatment show favorable effect on glycerol-induced acute renal failure in rats.

근위축성측삭경화증 가족 돌봄제공자의 심리사회적 안녕감에 영향을 미치는 요인 (Factors Influencing Psychosocial Well-Being in Family Caregivers of People with Amyotrophic Lateral Sclerosis)

  • 추현식;탁영란;김승현
    • 대한간호학회지
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    • 제48권4호
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    • pp.454-464
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    • 2018
  • Purpose: The purpose of this study was to identify factors influencing psychosocial well-being in family caregivers of patients with amyotrophic lateral sclerosis (ALS). Methods: A descriptive correlational design was used. The transactional model of stress and coping was used to investigate the psychosocial well-being of 137 family caregivers of patients with ALS. Data were collected through self-reported questionnaires from January to November 2016. Data were analyzed using an independent t-test, one-way ANOVA, Pearson's correlation, and hierarchical multiple regression analysis with the SPSS WIN 21.0 program. Results: The regression model had an adjusted $R^2$ of .49, which indicated that meaning-focused coping, social support, ALS patient-family caregiver relationship (especially a spousal relationship), and tracheostomy were significant predictors of caregivers' psychosocial well-being. Conclusion: Meaning-focused coping and social support significantly influenced caregivers' psychosocial well-being. Therefore, interventions to improve caregivers' psychosocial well-being must focus on increasing meaning-focused coping and social support resources.

The Investigation of Photolithographic Patterning Method for Polymer Light Emitting Diodes

  • Kim, Mi-Kyung;Lee, Jeong-Ik;Kim, Duck-Il;Oh, Ji-Young;Hwang, Chi-Sun;KoPark, Sang-He;Yang, Yong-Suk;Chu, Hye-Yong;Kim, Suk-Kyung;Hwang, Do-Hoon;Lee, Hyung-Jong
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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    • pp.592-594
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    • 2004
  • We have investigated the photolithographic patterning method of light emitting polymer film for polymer light emitting diodes (PLEDs). Blue light emitting polymers based on polyfluorene, which can be cured photochemically to yield an insoluble form, have been synthesized using Ni(0) mediated Yamamoto polymerization. The relationship between patterning property and several variables such as the intensity of the exposed UV light, the concentrations of additives, has been studied by using optical microscope analysis, UV/visible spectroscopy, and photoluminescence. We have successfully fabricated PLEDs composed of the patterned emissive layer and their electroluminescence property has been also investigated. In this presentation, the detailed photolithographic patterning method and its application for polymer light emitting display will be discussed.

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디스크 전극을 이용한 미세 전해 밀링 가공에서의 테이퍼 형상 방지 (Taper Reduction in Micro Electrochemical Milling Using Disk-type Electrode)

  • 김보현;이영수;최덕기;주종남
    • 한국정밀공학회지
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    • 제22권4호
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    • pp.167-172
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    • 2005
  • In this paper. micro electrochemical machining (ECM) for micro structure fabrications is presented. By applying ultra short pulses. the chemical reaction can be restricted only to the region very close to the electrode. Micro ECM is applied to machining micro structures through electrochemical milling process becasuse it doesn't suffer from tool wear. Using this method. 3D micro structures were machined on stainless steel. It was found that micro machining is possible with good surface quality in the low concentration electrolyte,0.1 M H₂SO₄. In ECM, as the machining depth increases, better flushing of electrolyte is required for sufficient ion supply. Layer-by-layer milling is advantageous in flushing. However, layer-by-layer milling causes taper of structures. To reduce the taper, application of a disk-type electrode was introduced. By electrochemical milling, various 3D micro structures including a hemisphere with 60 ㎛ diameter were fabricated.

유방에 발생한 화생성 암종의 세침흡인 세포학적 소견 - 1증례 보고 - (Fine Needle Aspiration Cytologic Findings of Metaplastic Carcinoma of the Breast - A Case Report -)

  • 민수기;차희정;김준미;주영채
    • 대한세포병리학회지
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    • 제7권2호
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    • pp.202-206
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    • 1996
  • Metaplastic carcinoma of the breast is a morphologically heterogenous group of neoplasms characterized by ductal adenocarcinoma with extensive squamous differentiation, a spindle-cell pattern of growth, and/or heterologous mesenchymal elements. We experienced a case of metaplastic carcinoma diagnosed by fine needle aspiration(FNA) and confirmed by radical mastectomy in a 46 year-old woman. The FNA cytologic findings included atypical squamous cells with kertinization tying singly and in clusters in a necrotic background. In addition, scattered spindle cells with pleomorphic large nuclei and prominent nucleoli were present in a hemorrhagic and necrotic background. The histopathologic findings showed moderately differentiated squamous cell carcinoma and highly pleomorphic sarcoma with chondroid component. The immunohistochemical stain revealed focal positive reaction for cytokeratin as well as diffuse reactivity for vimentin in the sarcomatous area.

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흉막강액에서 진단된 류마티스성 흉막염 - 세포학적 소견 1예 보고 - (Cytologic Findings of Rheumatoid Pleuritis in Pleural Effusion - A Case Report -)

  • 차희정;민수기;김준미;주영채
    • 대한세포병리학회지
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    • 제8권1호
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    • pp.47-51
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    • 1997
  • Patients with rheumatoid arthritis of any degree of severity or duration may develop necrotizing granulomatous pleuritis, a morphologic replica of the inflammatory reaction characteristic of rheumatoid synovitis and rheumatoid nodules. The principal feature is the background composed of granular, amorphous, particulate material or debris of various hues. The material is sometimes eosinophilic sometimes more cyanophilic, or even green in the Papanicolaou stain. Within this background are elongated, fibroblast-like epithelioid cells, numerous multinucleated giant cells and degenerating leukocytes. The combination of the debris, spindle epithelioid ceils, and multinucleated giant cells in fluid is pathognomonic for rheumatoid pleuritis. We experienced a hcase of rheumatoid pleuritis showing these characteristic cytologic findings. The patient was a 63 year-old man with positive rheumatoid factor. The pleual fluid specimen revealed elongated epithelioid cells and multinucleated giant cells on a background of amorphous granular material.

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Event Trigger Generator for Gravitational-Wave Data based on Hilbert-Huang Transform

  • Son, Edwin J.;Chu, Hyoungseok;Kim, Young-Min;Kim, Hwansun;Oh, John J.;Oh, Sang Hoon;Blackburn, Lindy;Hayama, Kazuhiro;Robinet, Florent
    • 천문학회보
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    • 제40권2호
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    • pp.55.4-56
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    • 2015
  • The Hilbert-Huang Transform (HHT) is composed of the Empirical Mode Decomposition (EMD) and the Hilbert Spectral Analysis (HSA). The EMD decomposes any time series data into a small number of components called the Intrinsic Mode Functions (IMFs), compared to the Discrete Fourier Transform which decomposes a data into a large number of harmonic functions. Each IMF has varying amplitude and frequency with respect to time, which can be obtained by HSA. The time resolution of the modes in HHT is the same as that of the given time series, while in the Wavelet Transform, Constant Q Transform and Short-Time Fourier Transform, there is a tradeoff between the resolutions in frequency and time. Based on the time-dependent amplitudes of IMFs, we develop an Event Trigger Generator and demonstrate its efficiency by applying it to gravitational-wave data.

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Identification of an antimicrobial peptide from human methionine sulfoxide reductase B3

  • Kim, Yong-Joon;Kwak, Geun-Hee;Lee, Chu-Hee;Kim, Hwa-Young
    • BMB Reports
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    • 제44권10호
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    • pp.669-673
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    • 2011
  • Human methionine sulfoxide reductase B3A (hMsrB3A) is an endoplasmic reticulum (ER) reductase that catalyzes the stereospecific reduction of methionine-R-sulfoxide to methionine in proteins. In this work, we identified an antimicrobial peptide from hMsrB3A protein. The N-terminal ER-targeting signal peptide (amino acids 1-31) conferred an antimicrobial effect in Escherichia coli cells. Sequence and structural analyses showed that the overall positively charged ER signal peptide had an Argand Pro-rich region and a potential hydrophobic ${\alpha}$-helical segment that contains 4 cysteine residues. The potential ${\alpha}$-helical region was essential for the antimicrobial activity within E. coli cells. A synthetic peptide, comprised of 2-26 amino acids of the signal peptide, was effective at killing Gram-negative E. coli, Klebsiella pneumoniae, and Salmonella paratyphi, but had no bactericidal activity against Gram-positive Staphylococcus aureus.

도토리껍질 추출액의 염색성에 관한 연구 (The Study on the Dyeing Properties of Acorn Shell Extract)

  • 주영주
    • 복식
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    • 제56권1호
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    • pp.143-149
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    • 2006
  • For the purpose of standardization and practicability of natural dyeing, the mordanting and dyeing properties of Acorn Shell was studied. Appropriate extraction, dyeing and mordanting condition of Acorn Shell were determined, and the effect of mordanting method on dye uptake and color fastness of dyed fabric was investigated. The maximum absorbance of Acorn Shell solution was at 287.5nm and 294nm. The pH effect was stable in the color difference changes. The optimum temperature to extract Acorn Shell was during 1 hour in $60^{\circ}C$. The effective dyeing temperature and time of silk were $80{\sim}100^{\circ}C$, 1hour. The silk fabrics dyed with Acorn Shell appeared yellow-brown. K/S value of dyeing fabrics was increased by mordant treatment. K/S value of post-mordanting was higher than pre-mordanting. Mordanting treatment attected color change of the dyed silk. In the case of Acorn Shell light fastness of appeared more than 3-5grades by post-mordanting. Abrasion fastness of appeared more than 3-5grades. Perspiration fastness of appered more than $3{\sim}5grades$ by mordant treatment but Cu mordant treatment was $2-5{\sim}4grades$. Dry-cleaning Fastness appered more than 4 grades except Cu mordant treatment. These fastness improvement were generally effective for mordant treatment, specially Al, Sn, Cr.