• Journal of Microbiology and Biotechnology
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• v.30 no.8
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• pp.1116-1123
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• 2020

Velvet antler (VA) is a historically traditional medicinal supplement and is well known in Asian countries for its pharmaceutical and health benefits. The objectives for this study were to optimize the hot water extraction (HWE) of VA for the Korean VA industry, and to determine the most effective pretreatment method among microwave (MW), ultrasonication (US), and enzymatic (EZ) techniques. Using response surface methodology, optimum extraction temperatures and times were determined by central composite design configuration based on extraction yield and sialic acid content. Various quality parameters of VA extract including yield, soluble solid, protein, and sialic acid contents were also compared with the conjunction of HWE and pretreatment. The yield and sialic acid content of VA extract were determined to be 40% and 0.73 mg/g, respectively, under an optimum temperature of 100℃ at 24 h of extraction time. The yields from VA extracts pretreated with MW, US, and EZ were 17.42%, 19.73%, and 29.15%, respectively. Among the tested commercial enzymes, pepsin was the most effective proteolytic enzyme and led to the highest yield (47.65%), soluble solids (4.03 °brix), protein (1.12 mg/ml), and sialic acid (3.04 mg/ml) contents from VA extract.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.2
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• pp.409-416
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• 1999

Microwave extraction system equipped with closed vessels was applied to confirm its capability of extracting ginseng solubles including saponin, which was monitored to optimize extraction con ditions by response surface methodology. Total yield increased with the decrease in particles size and more extraction steps. Soluble components were completely extracted by operating the system within 6 min per one step, which should be repeated by 3 or 4 times. Optimized conditions for maxi mum extraction of response variables(total yield, crude saponin) were 40~50% of ethanol concentration, about 140oC of extraction temperature, and within 6 min of the extraction time. The extraction effi ciency of total yield was dependent on the decrease of ethanol concentration, while crude saponin content was favored on the higher degree of ethanol concentration. According to the temperature guideline, below 90oC of extraction temperature, the optimal ranges of extraction conditions were predicted as 30~50% of ethanol concentration and 2.5~6.5 min of extraction time. Estimated values of total yield and crude saponin were in good agreement with experimental values.

• Food Science and Biotechnology
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• v.16 no.4
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• pp.565-571
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• 2007

This study was carried out to investigate an optimum condition for the high angiotensin-l converting enzyme (ACE) inhibitory activity and the yield on enzyme concentration, casein concentration, and hydrolysis time. The optimum condition was performed by response surface methodology for acquirement of casein hydrolysate of milk which shows high ACE inhibitory activity, Among 8 tested enzymes, Protamex showed the highest activation degree with 77.03 unit/g from casein. Their hydrolysis degrees of flovourzyme 500MG, protamex, mixture from 1% casein were 85.5, 88.5, and 93.5%, respectively. The ranges of enzyme concentration (0.25-1.25%), casein concentration (2.5-12.5%), and hydrolysis time (20-100 min) as 3 independent variables through preliminary experiments of the yield of casein hydrolysate and ACE inhibitory activity, and it shows optimum response surface at a saddle point. It shows enzyme concentration (0.64%), casein concentration (8.38%), and hydrolysis time (55.81 min) in the yield aspect and showed the highest activity at enzyme concentration (0.86%), casein concentration (5.97%), and hydrolysis time (63.86 min) in ACE inhibitory aspect. The $R^2$ value of a fitted optimum formula on the hydrolysis yield was 0.9751 as the significant level of 1%. The $R^2$ value of a fitted optimum formula on ACE inhibitory activity is 0.8398, and the significance is recognized in the range of 5%.

• Journal of Korean Association for Spatial Structures
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• v.18 no.1
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• pp.109-116
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• 2018

As the number of high-rise buildings increases, a mid-story isolation system has been proposed for high-rise buildings. Due to structural problems, an appropriate isolation layer displacement is required for an isolation system. In this study, the mid-story isolation system was designed and the seismic response of the structure was investigated by varying the yield strength and the horizontal stiffness of the seismic isolation system. To do this, a model with an isolation layer at the bottom of $15^{th}$ floor of a 20-story building was used as an example structure. Kobe(1995) and Nihonkai-Chubu(1983) earthquake are used as earthquake excitations. The yield strength and the horizontal stiffness of the seismic isolation system were varied to determine the seismic displacement and the story drift ratio of the structure. Based on the analytical results, as the yield strength and horizontal stiffness increase, the displacement of the isolation layer decreases. The story drift ratio decreases and then increases. The displacement of the isolation layer and the story drift ratio are inversely proportional. Increasing the displacement of the isolation layer to reduce the story drift ratio can cause the structure to become unstable. Therefore, an engineer should choose the appropriate yield strength and horizontal stiffness in consideration of the safety and efficiency of the structure when a mid-story isolation system for a high-rise building is designed.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.1
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• pp.16-19
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• 2012

Increasing rice grain yield is critical for feeding rapid increasing of Asian population. However, global warming effect may be negative for sustainable rice production. Therefore it is essential to develop technologies not only for increasing grain yield but also for reducing global warming effect. Biochar, which is carbonized biomass, has a great potential of carbon sequestration and soil quality improvement, which can contribute grain yield increasing. In this study, rice yield responses to biochar application on the rice cropping system were evaluated with field experiments under different water management practices at the research farm of the University of Missouri-Columbia Delta Research Center, Portageville, MO. Biochar (i.e., $4Mg\;ha^{-1}$) was produced using field scale pyrolyzer and incorporated into the field 4 months prior to planting. Rice was grown under three different water management practices. Result showed that no significant yield difference was found in the biochar application plots compared to rice hull and control plots from the 2 years field study at the very fertile soil. However, rainfed management results in severe reduction of yield. Research concludes that the biochar application does not significantly influence on rice yield increasing especially for very fertile soils.

• Earthquakes and Structures
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• v.3 no.2
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• pp.141-168
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• 2012

The Retrofit Yield Spectrum (RYS) is a new spectrum-based device that relates seismic demand of a retrofitted structure with the fundamental design parameters of the retrofit. This is obtained from superposition of Yield Point Spectra with design charts that summarize in pertinent spectrum-compatible coordinates the attributes of a number of alternative retrofit scenarios. Therefore, once the requirements for upgrading a given structure have been determined, the RYS enable direct insight of the sensitivity of the seismic response of the upgraded structure to the preliminary design decisions made while establishing the retrofit plan. By virtue of their spectrum-based origin, RYS are derived with reference to a single mode of structural vibration; a primary objective is to control the contribution of this mode in the retrofit design so as to produce a desirable distribution of damage at the ultimate limit state by removing soft storey formations and engaging the maximum number of structural members in deformation, in response to the input motion. Calculations are performed with reference to the yield-point, where secant stiffness is proportional to the flexural strength of reinforced concrete members. Derivation and use of the Retrofit Yield Spectra (RYS) refers to the seismic demand expressed either in terms of spectral acceleration, spectral displacement or interstory drift, at yield of the first storey. A reinforced concrete building that has been tested in full scale to a sequence of simulated earthquake excitations is used in the paper as a demonstration case study to examine the effectiveness of the proposed methodology.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.7
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• pp.899-904
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• 2001

A field trial on selection for increased live weight in Black Bengal (BB) goat was conducted over two generations. Parents of both sexes were selected (mass selection) based on mature body weight criteria set against age. A parallel randomly mated line was maintained to compare the response (R) of selection at birth. 3, 6, 9 and 12 months of age in both generations. Lactation yield (LY), average per day yield (APDY) and lactation length (LL) were evaluated in the selected line in comparison to randombreds as a result of correlated response. Live weights were significantly improved at onward bir:th in first generation and only at birth in second generation. Improvements (%) in live weight at 3, 6. 9 and 12 months in first generation were 17.6, 18.4, 16.6, and 12.0 at birth in second generation. Significant correlated R were found in LY and APDY. Results suggest that there may be a positive relationship between live weight and lactational traits in BB goats of Bangladesh. It was also concluded that such a field scheme can be effectively used for genetic improvement of goats in subsistence farming, at least for short term gain.

• Journal of the Earthquake Engineering Society of Korea
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• v.20 no.5
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• pp.319-329
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• 2016

The Eradi Quake System (EQS) is a seismic isolation bearing system designed to minimize forces and displacements experienced by structures subjected to ground motion. The EQS dissipates seismic energy through friction of Poly Tetra Fluoro Ethylene (PTFE) disk pad. In general, a force-displacement relationship of EQS has post yield stiffness hardening during large inelastic displacement. In this study, seismic responses of seismically isolated nuclear power plant (NPP) subjected to design basis earthquake (DBE) and beyond design basis earthquakes (150% DBE and 167% DBE) are compared considering the post yield stiffness hardening effect of EQS. From the results, it can be observed that if the post-yield stiffness hardening effect of EQS is increased, the displacement response of EQS is reduced, and the acceleration and shear responses of containment structures of NPP is increased.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.4
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• pp.515-520
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• 2010

The response of broiler chicks to intubation of nutrients (starch, casein, soybean oil or their combinations) into the crop immediately after hatch was evaluated for performance, intestinal development, meat yield and immune competence up to 35 d of age. A control group with no access to feed and two test groups fed either inert material (sawdust) or starter diet for the initial 24 h after hatch were compared with nutrient intubated groups (n = 7). A total of 300 broiler chicks were equally distributed to 10 dietary groups with 6 replicates of 5 chicks each. After 24 h of hatch, all groups were fed ad libitum the starter (0-21 d) and finisher diets (22-35 d). Results indicated that post-hatch intubation of starch into the crop significantly (p${\leq}$0.05) improved body weight (at 14 and 35 d of age), readyto-cook meat yields, weights of breast muscle and small intestine segments, cell-mediated immune response, ND titers and weight of bursa compared to chicks starved or fed sawdust during the initial 24 h after hatch. However, chicks with access to feed immediately after hatch or intubation of starch, soybean oil, starch+casein, starch+soybean oil or starch+casein+soybean oil exhibited similar positive effects. Intubation of casein either alone or in combination with soybean oil was superior to the starved or sawdust fed groups, but inferior to other groups for all the parameters studied. It was concluded from the study that intubation of starch individually or in combination with casein and/or soybean oil effectively circumvented the negative effects of post-hatch starvation for 24 h. Among the nutrients intubated, carbohydrate (starch) was better utilized by the chicks than protein (casein) or fat during the initial post-hatch period.

• Structural Engineering and Mechanics
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• v.25 no.1
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• pp.53-73
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• 2007

In this study, an effective load increment method for multi modal adaptive non-linear static (pushover) analysis (NSA) for building type structures is presented. In the method, lumped plastisicity approach is adopted and geometrical non-linearties (second-order effects) are included. Non-linear yield conditions of column elements and geometrical non-linearity effects between successive plastic sections are linearized. Thus, load increment needed for formation of plastic sections can be determined directly (without applying iteration or step-by-step techniques) by using linearized yield conditions. After formation of each plastic section, the higher mode effects are considered by utilizing the essentials of traditional response spectrum analysis at linearized regions between plastic sections. Changing dynamic properties due to plastification in the system are used on the calculation of modal lateral loads. Thus, the effects of stiffness changes and local mechanism at the system on lateral load distribution are included. By using the proposed method, solution can be obtained effectively for multi-mode whereby the properties change due to plastifications in the system. In the study, a new procedure for determination of modal lateral loads is also proposed. In order to evaluate the proposed method, a 20 story RC frame building is analyzed and compared with Non-linear Dynamic Analysis (NDA) results and FEMA 356 Non-linear Static Analysis (NSA) procedures using fixed loads distributions (first mode, SRSS and uniform distribution) in terms of different parameters. Second-order effects on response quantities and periods are also investigated. When the NDA results are taken as reference, it is seen that proposed method yield generally better results than all FEMA 356 procedures for all investigated response quantities.