• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.18 no.2
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• pp.138-144
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• 2007

Objectives: The aim of this study was to evaluate the reliability and validity of the Korean Version of the Diagnostic Interview Schedule for Children Version IV(DISC-IV), a highly structured diagnostic interview used to assess more than 30 psychiatric disorders in children and adolescents. Methods: A total of 91 study subjects, including 67 subjects who visited the child and adolescent psychiatry outpatient clinic at our institution and 24 community-based subjects, were assessed using the Korean Version of the DISC-IV. Clinical diagnosis was used as a gold standard for the examination of the validity of the DISC-IV. Forty-four of the study subjects were randomly selected for test-retest reliability measurement. Results: The validity of the Korean Version of the DISC-IV showed kappa values ranging from 0.25 to 0.40 in the clinical sample and 0.65 to 1.00 in the community sample. The sensitivities varied according to the diagnostic categories, but the specificities were excellent for all diagnostic entities. Conclusion: The Korean Version of the DISC-IV showed good reliability and validity in Korean children and adolescents. The Korean Version of the DISC-IV might be a useful tool for assessing psychiatric disorders in children and adolescents.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.1
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• pp.236-246
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• 2012

Hospital out-shopping by local patients has become more popular. In particular, many cancer patients have visited hospitals in the capital area to get better medical services regardless of how far the hospitals are from their home. However this kind of hospital out-shopping may discontinue medical treatment and cause a waste of medical resources including manpower. In addition, it creates additional economic and social expenses such as caretakers' transportation and lodging expenses. It is necessary to study patients who would take the medical treatment in Busan go to Seoul for better medical services are more satisfied based on objective data. For this, a questionnaire survey has been performed against 223 cancer patients who had a surgery in Busan and 187 patents who had an operation in Seoul. According to the survey, the patients who had an operation in the capital area(Group A) were more satisfied than the patients who had a surgery in Busan(Group B) in terms of convenience facilities, doctors' competence. However the Group A was very dissatisfied in terms of accessibility and satisfaction on overall medical services.

• Health Policy and Management
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• v.18 no.3
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• pp.58-89
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• 2008

The purpose of this study was to evaluate comparatively the content of the Expanded National Immunization Program according to the provision method between 2005 and 2006 in Korea. We assessed the impact of the mutually exclusive vaccination policy using the result reports of the 2005 and 2006 Demonstration Project and the related references by the content analysis. The public health centers paid vaccination fees to the private clinic and hospital in the 2005 Demonstration Project in Daegu metropolitan city and Gunpo city. But, the public health centers directly supplied free vaccination services to the children in the 2006 Demonstration Project in Gangneung city, Yangsan city, and Yeongi-gun. The total budgets of 2005 and 2006 Demonstration Project were 6.57 billion won and 0.65 billion won, respectively. The computerized registration rates and timeliness rates of administration of each vaccination had improved all in the 5 Demonstration Project regions. However, the computerized registration rates of most vaccination in Gunpo city were higher than those in the 2006 Demonstration Project regions except hepatitis B. Especially, the computerized registration rate of BCG was 48.3%, but the BCG coverage rate by the follow-up telephone survey was 99.8% in Daegu metropolitan city. The community parents in all the regions were satisfied because of expanding financial and geographical access to immunization coverage. In conclusions, from the aspect of the main outcomes, the implementation of two different financial immunization aids appears to be widely accepted among these parents and to have had an impact on vaccination coverage. In the future, the government must try to enact that the national immunization policy including under-immunised or incompletely immunised groups would be achieved by the affordable method of the public-private dynamics.

• Journal of Korean Society for Atmospheric Environment
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• v.34 no.4
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• pp.534-541
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• 2018

Concentrations of total particulate matter (TPM), $PM_{10}$ and $PM_{2.5}$ were measured at three different sites based on each different fuel type (solid, liquid and gas) used in thermal power plants operating in Yeosu and Gwangyang National Industrial Complexes during 2017. The highest concentrations of TPM, $PM_{10}$, and $PM_{2.5}$ were observed at the solid fuel facility, and these values were $3.356mg/Sm^3$, $2.342mg/Sm^3$ and $1.834mg/Sm^3$, respectively. The ratio of $PM_{2.5}$ to TPM was the highest value of 54.6% in solid fuel case, and the lowest was 35.7% found in liquid fuel case. As a result of analyzing 9 kinds of metal compound with respect to each particle size, the metal concentration of TPM is higher than those of $PM_{10}$ and $PM_{2.5}$ in all fuel types. Total concentrations of metal elements in TPM by fuel difference are $1.2702mg/Sm^3$ in solid fuel, 0.0603 mg/Sm3 in liquid fuel, and $0.0733mg/Sm^3$ in gas fuel, respectively. Relatively higher total metal concentration in gas fuel than in liquid fuel was found; and this could be higher Cr and Al concentrations in use of gas fuel. As a result of estimating the emission factors of each facility, in case of solid fuel, TPM emissions per electricity production were found to be 0.7080 kt/PJ, followed by liquid fuel and gas fuel. $PM_{10}$ and $PM_{2.5}$ emissions per hour of electricity production were similar to those of TPM.

• Journal of Korean Physical Therapy Science
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• v.19 no.3
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• pp.49-56
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• 2012

Background : The purpose of this study is to understand the effects of ankle joint taping on balancing abilities of the elderly and to provide preliminary data on preventing falls among the elderly. Methods : In this study, 20 students(8 male, 12 female) in their 20s from D University as well as 14 elderly(4 male, 10 female) in their 70s from S community center have participated. The participants were well informed about the experiment and voluntarily participated. We measured the difference in balancing ability before and after taping between the two groups using methods such as standing on single-leg stance, TUG, and plantar pressure. Kinesio taping, a stop-watch, and the EMED-system were used as equipment along with the SPSS 12.0 program, with a significance level of 0.05, to test the difference before and after taping between the two groups. Result : First, the 70s group showed a significant increase in the dorsal flexion angle after taping. Second, the 70s group showed a significant increase in duration time of standing on one foot after taping. Third, the 70s group's TUG time was significantly shorter. Fourth, the maximum peak value for static and dynamic plantar pressure showed a significant decrease after taping; and dynamic plantar pressure area value decreased as well within significant range. Conclusion : The study has shown that taping is effective on static dynamic balancing ability of the elderly.

• Journal of Korean Physical Therapy Science
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• v.18 no.1
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• pp.11-19
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• 2011

Purpose: The purpose of this study is to understand the effect of balance and gait when simultaneous application of Kinesio Taping on the lower extremities is done to improve the pattern of hemiplegic patients asymmetric lower extremity. Methods: This study was performed with 7 patients who have hemiplegia symptoms due to stoke. The taping on the paralyzed side was done on tibialis anterior, gluteus medius, gluteus maximus and psoas major and the taping on the unparalyzed side was done on the calf muscle and quadriceps. Berg Balance Scale(BBS) and Time Up and Go Test(TUG) was used to assessment the balance and gait of the patient after the kinesio taping was done on the lower extremities. The results of the test was analyzed by Wilcoxon Signed Rank Test on SPSS(Ver. 10.1). Results: When the taping was done on the paralyzed side, there was a significant improvement of balance and gait in BBS and TUG. When the taping was done on the lower extremities, it showed significant improvement of balance and gait, compared to when the taping was only done on the paralyzed side, according to BBS and TUG. Conclusion: The result of this study shows that the simultaneous taping of the lower extremities of the hemiplegic patients improves balance and gait by improving the pattern of patients lower extremities.

• Journal of Preventive Medicine and Public Health
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• v.35 no.4
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• pp.295-304
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• 2002

Objectives : This study was carried out to investigate the cause, magnitude and transmission route of the cholera outbreak in 2001 Methods : The study population were those persons who ingested foods at the restaurant, were confirmed as cholera patients, had symptoms of diarrhea and sewed as workers at the restaurant. A questionnaire survey and microbiological examinations on the microbes isolated from rectal swabs were conducted. Of the cases, 316 food histories were surveyed by an analysis of the restaurant menu. Results : There were 139 confirmed cases of cholera reported in Korea in 2001. Of these, 104 were related to the restaurant. By region, Gyeongsangbuk-do had the highest incidence with 91 cases. Of these 91 cases, 74 had ingested foods at the restaurant, 2 were employees and 3 were secondary infection cases within the families. The results of the odds ratio analysis of the 316 persons having ingested foods at the restaurant were as follows: sandwiches 5.07 (95% CI, 1.85-14.59), soybean curd 2.45 (95% CI, 1.09-5.56), noodles 2.34 (95% CI, 1.24-4.42), steamed squid 2.01 (95% CI, 1.17-3.47) and vinegared rice 1.82 (95%, CI, 1.08-3.09). It was certain the restaurant in question was the cause of the 2001 outbreak. Conclusions : We suspected that more than one restaurant employee contaminated foods served at the restaurant. In addition, eating raw fishes purchased at the Pohang Fisheries infected the employees of the restaurant. There is a possibility that these raw fishes were themselves contaminated by cholera bacilli in the sea.

• Journal of Korean Medical Science
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• v.33 no.52
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• pp.336.1-336.12
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• 2018

Background: We aimed to investigate mucosal immunity related to forkhead box P3 ($FOXP3^+$) regulatory T (Treg) cells, T helper 17 (Th17) cells and cytokines in pediatric inflammatory bowel disease (IBD). Methods: Mucosal tissues from terminal ileum and colon and serum samples were collected from twelve children with IBD and seven control children. Immunohistochemical staining was done using anti-human FOXP3 and anti-$ROR{\gamma}t$ antibodies. Serum levels of cytokines were analyzed using a multiplex assay covering interleukin $(IL)-1{\beta}$, IL-4, IL-6, IL-10, IL-17A/F, IL-21, IL-22, IL-23, IL-25, IL-31, IL-33, interferon $(IFN)-{\gamma}$, soluble CD40L, and tumor necrosis factor-${\alpha}$. Results: $FOXP3^+$ Treg cells in the lamina propria (LP) of terminal ileum of patients with Crohn's disease were significantly (P < 0.05) higher than those in the healthy controls. $ROR{\gamma}t^+$ T cells of terminal ileum tended to be higher in Crohn's disease than those in the control. In the multiplex assay, serum concentrations (pg/mL) of IL-4 ($9.6{\pm}1.5$ vs. $12.7{\pm}3.0$), IL-21 ($14.9{\pm}1.5$ vs. $26.4{\pm}9.1$), IL-33 ($14.3{\pm}0.9$ vs. $19.1{\pm}5.3$), and $IFN-{\gamma}$ ($15.2{\pm}5.9$ vs. $50.2{\pm}42.4$) were significantly lower in Crohn's disease than those in the control group. However, serum concentration of IL-6 ($119.1{\pm}79.6$ vs. $52.9{\pm}39.1$) was higher in Crohn's disease than that in the control. Serum concentrations of IL-17A ($64.2{\pm}17.2$ vs. $28.3{\pm}10.0$) and IL-22 ($37.5{\pm}8.8$ vs. $27.2{\pm}3.7$) were significantly higher in ulcerative colitis than those in Crohn's disease. Conclusion: Mucosal immunity analysis showed increased $FOXP3^+$ T reg cells in the LP with Crohn's disease while Th17 cell polarizing and signature cytokines were decreased in the serum samples of Crohn's disease but increased in ulcerative colitis.

• Proceedings of KOSOMES biannual meeting
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• 2008.05a
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• pp.185-189
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• 2008

This study was conducted to find out the effects of relationship between ocean conditions and snowfall when cold and dry continental air mass passes through the West Sea of Korea. Route of continental high atmospheric pressure can cause effect on snowfall at the west regions (Inchoen, Gunsan, Mokpo) of the Korean Peninsula. The continental high atmospheric pressure extend from the southern China to western coastal region of the Korean Peninsula during the December, and it extend from the north side of China through Bohai Sea and Yodong Peninsula to central area of the Korean Peninsula during the February. Therefore, more snowfall recorded in Incheon is higher during Feb. than Dec.. whereas Gunsan and Mokpo is the opposite. The heavy snowfall at the western coastal region of Korea was caused by loss of the heat from the ocean to air when it's higher than $100W/m^2$. the heavy snowfall was also observed when the arrangement of continental high atmospheric pressure and low pressure was high at the West and low at the East, which formed a front in West and when the wind blow from the North or North West at the speed of $4\sim8m/sec$. There were not much relation between salinity in the western sea and snowfall in the western coastal region of Korea.

• Korean Journal of Medicinal Crop Science
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• v.28 no.6
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• pp.395-411
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• 2020

Background: This study investigated the anti-obesity effect of the flavonoid rich fraction (FRF) and its constituent, rutin obtained from the leaf of Morus alba L., on the lipid accumulation mechanism in 3T3-L1 adipocyte and C57BL/6 mouse models. Methods and Results: In Oil Red O staining, FRF (1,000 ㎍/㎖) treatments showed inhibition rate of 35.39% in lipid accumulation compared to that in the control. AdipoRedTM assay indicated that the triglyceride content in 3T3-L1 adipocytes treated with FRF (1,000 ㎍/㎖) was reduced to 23.22%, and free glycerol content was increased to 106.04% that of the control. FRF and its major constituent, rutin affected mRNA gene expression. Rutin contributed to the inhibition of Sterol regulatory element binding protein-1c (SREBP-1c) gene expression, and inhibited the transcription factors SREBP-1c, peroxisome proliferator-activated receptor gamma (PPAR-γ), CCAAT/enhancer binding protein α (C/EBPα), fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC). In addition, the effect of FRF administration on obesity development in C57BL/6 mice fed high-fat diet (HFD) was investigated. FRF suppressed weight gain, and reduced liver triglyceride and leptin secretion. FRF exerted potential anti-inflammatory effects by improving insulin resistance and adiponectin levels, and could thus be used to help counteract obesity. The mRNA expressions of PPAR-γ, FAS, ACC, and CPT-1 were determined in liver tissue. Quantitative real-time PCR analysis was also performed to evaluate the expression of IL-1β, IL-6, and TNF-α in epididymal adipose tissue. Compared to the control group, mice fed the HFD showed the up-regulation in PPAR-γ, FAS, IL-6, and TNF-α genes, and down-regulation in CPT1 gene expression. FRF treatement markedly reduced the expression of PPAR-γ, FAS, IL-6, and TNF-α compared to those in HFD control, whereas increased the expression level of CPT1. Conclusions: These results suggest that the FRF and its major active constituent, rutin, can be used as effective anti-obesity agents.