• Reproductive and Developmental Biology
• /
• 제35권1호
• /
• pp.105-113
• /
• 2011

The present study investigated the nuclear remodeling, development potential with telomerase activity and transcription level of X-linked genes (ANT3, HPRT, MeCP2, RPS4X, XIAP, XIST and ZFX) in the bovine somatic cell nuclear transfer (SCNT) embryos using two different fusion and activation methods. Female adult fibroblasts were injected into perivitelline space of in vitro matured oocytes. The oocyte-nucleus complexes were fused and followed by immediately either activated (Group 1), or activated at 1 h post-fusion (hpf) (Group 2), respectively. The incidence of normal premature chromosome condensation (PCC) at 1 hpf was slightly increased in the Group 2, compared to those of Group 1, but there was no significant (p<0.05) difference. The incidence of normal pronucleus (PN) and chromosome spread at 5 and 18 hpf were significantly (p<0.05) higher in the Group 2 than those of Group 1. The cleavage rate to 2-cell stage, developmental rate to blastocyst stage, and the mean number of total and ICM cell numbers were significantly (p<0.05) higher in the Group 2, compared to those of Group 1. Level of telomerase activity was significantly (p<0.05) higher in the SCNT blastocysts of Group 2, compared to those of Group 1. Transcript levels of HPRT, MeCP2 and XIST were not significantly (p<0.05) different between blastocysts of Group 1 and 2. However, transcript level of ANT3, RPS4X, XIAP and ZFX were significantly (p<0.05) up-regulated in the SCNT blastocysts of Group 2, compared to those of Group 1. Taken together, it is concluded that oocyte activation at 1 hpf induces the enhanced developmental potential by efficient nuclear remodeling and subsequent facilitation of the nuclear reprogramming of bovine SCNT embryos.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권8호
• /
• pp.3961-3965
• /
• 2012

Objective: To compare the clinical effects of concurrent radiochemotherapy with those of radiotherapy in treating locally advanced nasopharyngeal carcinoma (Stage III~IVa). Methods: A total of 95 patients suffering from nasopharyngeal carcinoma (Stage III~IVa) were divided into two groups: concurrent radiochemotherapy (Group CCRT, n=49) and radiotherapy (Group RT, n=46). The two groups were both delivered conventional fractionated radiotherapy, while Group CCRT also received three cycles of PF (DDP+5-Fu) or PLF (DDP+5-Fu+CF) chemotherapy. Results: The complete remission rate and total remission rate of Group CCRT were higher than those of Group RT ($X^2$=4.72~7.19, P<0.05). The one-year overall survival (OS) rate calculated by the life table method, was also higher than that of Group RT ($X^2$=4.24, P<0.05) as well as the 3-year OS rate, nasopharyngeal control rate and cervical lymph nodes' control rate ($X^2$=4.28~4.40, P<0.05). In addition, the 5-year OS and metastasis-free rates of Group CCRT were higher than those of Group RT and the differences were of statistical importance ($X^2$=3.96~8.26, P<0.05). However, acute toxicity was also obviously higher, the difference in gastrointestinal reactions being statistically significant ($X^2$=11.70, P<0.05). Conclusion: This study demonstrated that concurrent radiochemotherapy could improve the remission rate, overall survival rate and locally control rate. The toxicity of concurrent radiochemotherapy could be tolerated by the patients.

• Journal of applied mathematics & informatics
• /
• 제38권3_4호
• /
• pp.221-238
• /
• 2020

Let G = (V (G), E(G)) be a graph and let g : V (G) → S₃ be a function. For each edge xy assign the label r where r is the remainder when o(g(x)) is divided by o(g(y)) or o(g(y)) is divided by o(g(x)) according as o(g(x)) ≥ o(g(y)) or o(g(y)) ≥ o(g(x)). The function g is called a group S₃ cordial remainder labeling of G if |v_g(i)-v_g(j)| ≤ 1 and |e_g(1)-e_g(0)| ≤ 1, where v_g(j) denotes the number of vertices labeled with j and e_g(i) denotes the number of edges labeled with i (i = 0, 1). A graph G which admits a group S₃ cordial remainder labeling is called a group S₃ cordial remainder graph. In this paper, we prove that subdivision of graphs admit a group S₃ cordial remainder labeling.

• The Korean Journal of Pain
• /
• 제10권2호
• /
• pp.231-234
• /
• 1997

Background: The aim of this study was to examine the precise spreading pattern of contrast media in small increments in rabbits. Following pentobarbital anesthesia, the epidural puncture was done surgically with a blunt hook. Methods: The tip of epidural catheter was located at the mid-portion of T7 and T12, in the T7 group (n=7) and T12 group (n=8), respectively. Injection of the contrast media was started at 0.1 mL/kg and increased by 0.1 mL/kg up to a maximum of 0.6, mL/kg, under fluoroscopy. Results: In both groups, the extent of spread increased continuously as a Starling resistor with increasing injected volume(T7 group: $y=4.0+41.8x-28.1x^2$, T12 group: $y=0.2+57.7x-43.5x^2$) the total spread of contrast media was similar. The contrast media spread equally, both rostral and caudal, from catheter tip in T7 group; media spread approximately twice as far rostral as compared to caudal in T12 group (P<0.05). Conclusions: In rabbits, the position of epidural catheter tip should be positioned 2~3 segments below the aimed segment in lower thoracic or lumbar region, whereas in mid-thoracic region it should be positioned close to the level of aimed segment. Rabbits have relatively small epidural space therefore, the volume of injectant should be carefully determined with the suggested equations of this study.

• Journal of applied mathematics & informatics
• /
• 제39권1_2호
• /
• pp.223-237
• /
• 2021

Let G = (V (G), E(G)) be a graph and let g : V (G) → S3 be a function. For each edge xy assign the label r where r is the remainder when o(g(x)) is divided by o(g(y)) or o(g(y)) is divided by o(g(x)) according as o(g(x)) ≥ o(g(y)) or o(g(y)) ≥ o(g(x)). The function g is called a group S3 cordial remainder labeling of G if |vg(i)-vg(j)| ≤ 1 and |eg(1)-eg(0)| ≤ 1, where vg(j) denotes the number of vertices labeled with j and eg(i) denotes the number of edges labeled with i (i = 0, 1). A graph G which admits a group S3 cordial remainder labeling is called a group S3 cordial remainder graph. In this paper, we prove that square of the path, duplication of a vertex by a new edge in path and cycle graphs, duplication of an edge by a new vertex in path and cycle graphs and total graph of cycle and path graphs admit a group S3 cordial remainder labeling.

• 한국운동역학회지
• /
• 제12권2호
• /
• pp.381-392
• /
• 2002

본 연구는 볼링의 운동학적 변인들을 규명하고 변인들간의 관계를 분석하여 볼링의 운동학적 변인들에 대한 주요인 구조를 파악할 뿐 아니라 나아가 본 연구를 통하여 볼링 지도자와 볼러들에게 경기력 향상에 관한 유익한 자료를 제공하고자 한다. 볼링의 운동학적 변인을 분석하고 변인들간의 관계 및 중요 요인을 분석함으로써 볼러들과 지도자들에게 유익한 자료를 제공하기 위해 시도되었으며 프로 1명, 국가대표 2명, 일반 볼러 6명으로 선정하였으며 분석시 방향의 일치성을 위해 모두 오른손잡이로 선정하였다. 스트라이크 포켓 존(1-3번핀 사이)에 볼이 진입된 시기만을 선택하였으며 선택된 시기 가운데 스트라이크가 발생된 3회의 시기와 스트라이크가 발생되지 않는 3회의 시기로 총 54회의 시기 가운데 2회의 시기를 제외하고 52회의 시기를 선택하여 분석하였다. 볼링의 운동학적 변인들의 집단간 차이를 보기위한 t-test결과 x1(오른쪽 어깨 위치), x2(볼중심 위치), x8(볼의 회전수), x9(손끝 위치), x10(손등위치), x11(손끝 속도), x12(손등 속도), x13(손등 각도)는 집단간 유의한 차이가 나타났지만, x3(오른쪽 어깨 속도), x5(오른쪽 손목 각도), x6(오른쪽 어깨 각도), x7(소요시간)은 집단간 유의한 차이가 나타나지 않았다. x8(볼의 회전수)의 경우 우수집단이 $12.25{\pm}0.90$, 비우수집단이 $8.39{\pm}1.88$로 집단간 평균차는 3.86이며 p<.001수준에서 t = 7.48로 유의한 차이가 나타났다. 요인점수는 관측대상이 각 변수에 대해 회답한 결과를 요인별 가중치를 이용하여 요인 공간상의 점수로 변환시켜 연구자가 각 관측대상의 요인 공간상의 위치를 파악할 수 있게 해준다.

• Journal of applied mathematics & informatics
• /
• 제17권1_2_3호
• /
• pp.771-778
• /
• 2005

In this paper we shall give some group properties derived from the characteristic ring-module $_X(M)$, using the fact that $_X(M)_H$ is a conjugate to $_X(M)_{Ha}$ when M is an invertible right R-module. Also we shall prove that_X(M)$ is group-isomorphic to TR and some normal subgroup properties if M is invertible and R is commutative.

• 대한수학회지
• /
• 제46권4호
• /
• pp.675-689
• /
• 2009

As a sequel to the papers [2, 3], we will complete our identification of the groups of units of the finite local rings $\mathbb{Z}_4$[X]/($X^k$ + 2t(X), $2X^{\gamma}$) which is the most general type of finite local rings with a single nilpotent generator over $\mathbb{Z}_4$.

• 한국수학교육학회지시리즈B:순수및응용수학
• /
• 제16권2호
• /
• pp.193-198
• /
• 2009

In the previous work [5] we have determined the group ${{\varepsilon}_{\sharp}}^{dim+r}^{dim+r}(X)$ for $X\;=\;M(Z_q,\;n+1){\vee}M(Z_q,\;n)$ for all integers q > 1. In this paper, we investigate the group ${{\varepsilon}_{\sharp}}^{dim+r}(X)$ for $X\;=\;M(Z{\oplus}Z_q,\;n+1){\vee}M(Z{\oplus}Z_q,\;n)$ for all odd numbers q > 1.

• 한국수소및신에너지학회논문집
• /
• 제18권2호
• /
• pp.124-131
• /
• 2007

Methane is partially oxidized to produce the syngas by the lattice oxygen of metal oxides in the absence of gaseous oxygen. The present work deals with ferrite including copper component, which does not chemisorb methane, to investigate the suppression of the carbon deposition during the reduction of metal oxides by methane. Iron-based oxides of $Cu_xFe_{3-x}O_4$(X=0.25, 0.5, 1.0) was synthesized by the co-precipitation method. Thermogravimetric Analysis(TGA) was used to observe the isothermal reduction behavior of $Cu_xFe_{3-x}O_4$ and $Fe_3O_4$ at $600-900^{\circ}C$ under methane atmosphere. The crystal structures of reduced specimens were characterized by X-rays powder diffraction(XRD) technique. From the analyses of TGA, it is concluded that the reduction kinetics of $CuFe_2O_4$ was the fastest among $Fe_3O_4$ and $Cu_xFe_{3-x}O_4$(X=0.25, 0.5, 1.0). The X-ray diffraction analyses indicated that $Cu_xFe_{3-x}O_4$ was decomposed to Cu and $Fe_3O_4$ phase at $600^{\circ}C$ and was reduced to Cu and Fe phase at $800^{\circ}C$. $Fe_3O_4$, which was reduced at $900^{\circ}C$, showed Fe, graphite and $Fe_3C$ phases. On the contrary, $Cu_xFe_{3-x}O_4$ does not show the graphite or $Fe_3C$ phases. This results infer that Cu component suppress the carbon deposition on Cu-ferrite.