• The Korean journal of internal medicine
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• v.33 no.6
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• pp.1194-1202
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• 2018

Background/Aims: This study evaluated the role of hypomethylating agents (HMA) compared to best supportive care (BSC) for patients with high or very-high (H/VH) risk myelodysplastic syndrome (MDS) according to the Revised International Prognostic Scoring System. Methods: A total of 279 H/VH risk MDS patients registered in the Korean MDS Working Party database were retrospectively analyzed. Results: HMA therapy was administered to 205 patients (73.5%), including 31 patients (11.1%) who then received allogeneic hematopoietic cell transplantation (allo-HCT), while 74 patients (26.5%) received BSC or allo-HCT without HMA. The 3-year overall survival (OS) rates were $53.1%{\pm}10.7%$ for allo-HCT with HMA, $75%{\pm}21.7%$ for allo-HCT without HMA, $17.3%{\pm}3.6%$ for HMA, and $20.8%{\pm}6.9%$ for BSC groups (p < 0.001). In the multivariate analysis, only allo-HCT was related with favorable OS (hazard ratio [HR], 0.356; p = 0.002), while very poor cytogenetic risk (HR, 5.696; p = 0.042), age ${\geq}65years$ (HR, 1.578; p = 0.022), Eastern Cooperative Oncology Group performance status (ECOG PS) 2 to 4 (HR, 2.837; p < 0.001), and transformation to acute myeloid leukemia (AML) (HR, 1.901; p = 0.001) all had an adverse effect on OS. Conclusions: For the H/VH risk group, very poor cytogenetic risk, age ${\geq}65years$, ECOG PS 2 to 4, and AML transformation were poor prognostic factors. HMA showed no benefit in terms of OS when compared to BSC. Allo-HCT was the only factor predicting a favorable long-term outcome. The use of HMA therapy did not seem to have an adverse effect on the transplantation outcomes. However, the conclusion of this study should be carefully interpreted and proven by large scale research in the future.

• The Korean journal of internal medicine
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• v.33 no.6
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• pp.1111-1118
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• 2018

Background/Aims: Chest pain is an essential symptom in the diagnosis of acute coronary syndrome (ACS). One-third of patients with ACS present atypically, which can influence their receiving timely lifesaving therapy. Methods: A total of 617 NSTEMI patients from the Korea Acute MI Registry (KAMIR) and the Korea Working Group on MI (KorMI) databases were analyzed. The study population was divided into two groups by symptoms at presentation (typical symptoms group, 128; atypical symptoms groups, 128). Results: In this study population, 23% of patients presented without chest pain. After propensity score matching, the contact-to-device time ($2,618{\pm}381minutes$ vs. $1,739{\pm}241minutes$, p = 0.050), the symptoms-to-balloon time ($3,426{\pm}389minutes$ vs. $2,366{\pm}255minutes$, p = 0.024), and the door-to-balloon time ($2,339{\pm}380minutes$ vs. $1,544{\pm}244minutes$, p = 0.002) were significantly higher in the patients with atypical symptoms than in those with typical symptoms, respectively. Atypical symptoms were an independent predictor for 1-year mortality (hazard ratio, 2.820; 95% confidence interval, 1.058 to 7.515; p = 0.038). The Kaplan-Meier estimates showed higher risk for 12-month mortality in patients with atypical symptoms (p = 0.048) and no significant difference for 12-month major adverse cardiac events (p = 0.487). Conclusions: Acute myocardial infarction patients with atypical symptoms were not rare in clinical practice and showed a high risk of delayed reperfusion therapy. After imbalance between the groups was minimized by use of propensity score matching, patients who presented atypically had a high mortality rate.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.441-453
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• 2018

This study was conducted to understand and describe Korean nurses' perception of person-centered care for elderly patients in long-term care hospitals. Qualitative data were collected through four focus group interviews consisting of 21 nurses working in four long-term care hospitals in Jeolla and Gyeongsang provinces. Participants completed interviews from July 19 to 30, 2018. All interviews were recorded, transcribed, and analyzed by employing the thematic analysis method. Six main themes for the attributes of person-centered care for elderly patients in the long-term care hospitals were conceptualized: respecting individual needs, walking to the end, supporting hidden dreams, becoming a family partner, helping patients live like they are at home, and changing culture. Person-centered care perceived by nurses was conducted to provide individualized nursing according to elderly's preferences and help them discover the value and meaning of life through various activity programs. Nurses also recognized person-centered care to maintain cooperative relationships with their family members and share their decision-making process, as well as to form a physical environment and organizational culture that respects the rights and autonomy of the elderly. Based on the results of this study, it is necessary to identify the diverse needs of the elderly and develop nursing intervention programs based on person-centered care.

• The Journal of the Korea Contents Association
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• v.18 no.12
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• pp.595-610
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• 2018

It is becoming common that the lack of child care due to changes in social structure and family function should be serviced at society and at the national level. Interest in child care services in child care facilities also increased. The purpose of this study is to examine the effect of organizational culture on child care respect for young children's rights that is needed to improve the quality of child care services. The questionnaire was administered to 340 day care teachers working in day care facilities and statistical analysis was performed using SPSS 22.0 statistical program. An analysis of the impact of organizational culture on child care among infants and toddlers showed that development culture, rational culture, collective culture, and hierarchical culture, which are sub-factors of organizational culture, have statistically significant on day -to-day respect, and child- first interests. The degree of influence was shown in the order of development culture, hierarchical culture, and rational culture. In particular, the influence of group culture is very low, which has been proven to differ depending on the type of organizational culture. These results show that the organizational culture of child care facilities affects child care respect for young children's rights. In the end, we suggested the theoretical and practical implications of this study, presented limitations and future research directions.

• The Journal of the Korea Contents Association
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• v.19 no.3
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• pp.313-327
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• 2019

The purpose of this study was to identify the effect of new graduate nurses' empathy and their perceived preceptors' empathy on job satisfaction, job stress and turnover intention. For this purpose, a survey was conducted on new graduate nurses who were under 12 months old while working at three medical institutions that operated the preceptorship. In the preceptorship according to adult learning theory, the preceptors need to create a psychological environment for the new graduate nurses, and their empathy should be perceived by new graduate nurses. The study revealed that the new graduate nurses group with high level of empathy had high levels of job satisfaction, low job stress, and low degree of turnover intention, and the level of empathy affects job satisfaction of new graduate nurses. The new graduate nurses group with low level of perceived preceptor's empathy had low job satisfaction, high job stress, and high degree of turnover intention, and their perceived preceptor's empathy affected job stress and turnover intention. Based on these results, we suggest the introduction of a program to enhance empathy for new graduate nurses and preceptors.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.7
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• pp.363-371
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• 2019

The purpose of this research is to provide data for the relations between lifestyle, stress and hypertension in a group of construction Temporary employee. The methods taken in this study was to survey the general characteristics and stress in the group, and figure out the relations between lifestyle and hypertension. This study targeted at 301 Temporary employee. in Young-dong for six months (2014~2015). Data analysis used errors and percentages, chi-square tests, one-way ANOVA analysis, independent sample t-test, chi-square test and multivariate logistic regression. The study shows that no relations between age and hypertension, but according to job characteristics, aggravate lifestyle just like smoking(P=0.049), eating habit(P=0.012), physical(p=0.022) & psychological(p=0.011) state there is an effect on hypertension. Based on the results of this study, it is found that temporary workers in small and medium-sized construction companies with high work-related disaster rates need to improve their living habits and physical psychological conditions and manage high blood pressure, as well as research and management of chronic diseases such as obesity, diabetes and dyslipidemia.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.755-765
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• 2021

The objectives of this study are to subdivide the group of elderly population into the liberation generation as a poor generation that experienced the barley hump, and the baby boom generation to verify differences in the mean of social capital and well-being between those groups of two generations, to verify the effects of social capital on the well-being, and then to review differences between those groups of two generations regarding the effects of subfactors of social capital on the well-being. This study collected and analyzed data from 200 people excluding missing values from the baby boom generation and liberation generation born in 1945-1963, in the D region from July 1st to July 31st, 2018. The main results of this study are as follows. in the results of comparatively reviewing the social capital having effects on the well-being of each group of liberation generation and baby boom generation, when relieving the statistical significance level to 90%, the network was working as a variable having effects on both groups. In this case, when mutually comparing the influence of regression coefficient as �� value, the network had a relatively larger effect on the well-being of the liberation generation.

• 한국사회정책
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• v.24 no.1
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• pp.117-151
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• 2017

This study explored the relationship between quitting time and subsequent time allocation of full-time workers with young children. First, as a result of sub-group difference analysis of subsequent time allocation by quitting time, the group who finished their work early used their additional time mostly for housework and care work. And if the workers finish their work late, they decreased their housework and active leisure time first, and then supplementally reduced their care work and passive leisure time. In addition, SUR analysis showed that as the workers finish their work earlier, the proportion of housework, care work and active leisure among five activities was getting higher. Last but not least, it was verified that the relationship between the quitting time and the subsequent time allocation was moderated by gender in housework, care work, and regenerative activity. This research can contribute to the development of debate on work-life balance of workers' by providing the concrete and detailed results.

• Korean Journal of Psychosomatic Medicine
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• v.28 no.2
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• pp.135-142
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• 2020

Objectives : To identify the relationship between somatization, stress, depression, anxiety, and psychological symptoms risk for nurses working in the intensive care unit. Create clinical evidence of psychosomatic medicine research and complement the meaning of somatization. Methods : Seventy of the mental health checkups conducted by the National Mental Health Center among the nurses using tools including Perceived Stress scale, Fatigue Severity Scale, Patient Health questionnaire-15, Korean Beck Depression Inventory, Korean Beck Anxiety Inventory, and Symptom Checklist-90-Revision. Results : 12.9% of the patients experienced more than moderate somatization. There was no statistical relationship between somatization and psychological stress perception, but feeling of anxiety and decreased self-confidence were related to the level of somatization. The group with severe somatization experienced more depression and anxiety. The group with high physical fatigue also had no statistical relationship with psychological stress perception, but had an effect on the feeling of tension, stress, or decreased control. Physical fatigue level was increased by experience of depression, not by anxiety. For psychological symptoms the higher the level of somatization, the higher the obsession and hostility was explored. In the linear regression model, stress, depression, and anxiety accounted for 39.3% of somatization and 16.1% of physical fatigue symptoms. Conclusions : We can estimate the decrease in stress cognitive symptoms, accompanying depression and anxiety, compulsion and hostility as characteristics of somatization. The causal relationship between somatization and psychological symptoms cannot be confirmed in this study, but the interrelationships are observed, can be referred to mediation strategies.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.5
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• pp.729-740
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• 2022

This study analyzed the effects of job stress and sleep disorders on sleepiness during the daytime for a night-shift urban railway crew. As a result of the analysis, measurements on a daytime sleepiness index were higher for the crew than those during other working hours, indicating that the degrees of sleepiness and drowsiness were severe. Afterwards, aromatic essential oils, which are generally known to help relieve sleep disorders and stress, were utilized to verify the effect on stress on night-shift workers. The experimental group treated with aromatherapy was found to show improved stress reduction and overall activity levels in the autonomic nervous system compared to an untreated control group. This study proves that night work by an urban railway crew negatively affects stress levels by increasing stress and negatively affects the autonomous nervous system, also showing that an aromatherapy treatment can be a good alternative to alleviate these conditions. The results of this study are expected to help prevent safety accidents by relieving the stress of nighttime workers.