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Recent Studies of Breast Cancer in Traditional Chinese Medicine Journals (중의학 논문에 나타난 유방암의 연구 동향에 대한 고찰 - 중의학 논문을 중심으로 -)

  • Jerng, Ui-Min;Jeong, Jong-Soo;Park, Jae-Woo;Jung, Hyun-Sik;Yoon, Seong-Woo
    • The Journal of Korean Obstetrics and Gynecology
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    • v.22 no.1
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    • pp.263-278
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    • 2009
  • Purpose: The purpose of this study is to research trends in the study of breast cancer in Traditional Chinese Medicine (TCM) and to establish the further direction for its study. Methods: We reviewed TCM papers published in the last 29 years (1979-2008). Results: 1. We researched 49 papers and the patterns of study were as follows: in vitro studies were 27 papers (55.1%), in vivo studies were 9 papers (18.4%) and clinical studies were 19 papers (38.8%). 2. In vitro studies on breast cancer research in TCM were focused on cytotoxicity (17 papers) and apoptosis (8 papers). Most of in vivo studies (6 papers) were done for the purpose of inducing growth suppression of tumor cell after administration of the test drug. Each drug acted on this effect through various types of mechanism. 3. Unlike in vitro and in vivo studies, clinical studies on growth suppression of tumor cell were rare (4 papers). Most of the studies were focused on reduction of side effect of chemotherapy or synergistic effect with chemotherapy (7 papers), immune regulation (7 papers), and improvement of quality of life (6 papers). 4. Among the treatment method we reviewed, 'Runing Ⅱ(Ⅱ號方)' was the only medication that further studied as clinical trial after experimental study. 5. Since almost all studies have defects like poorly designed model or insufficient data description, it was difficult to make any definite conclusion about these studies. Conclusion: More subsequent clinical studies based on experimental study will be needed afterwards. Strict and high-level study design with detailed description will be needed in further study.

Occupancy Probability Estimation of Endangered Species Clithon retropictus (멸종위기종인 기수갈고둥의 잠재적 서식지 예측을 위한 점유 확률 추정)

  • Park, Woong-Bae;Lim, Sung-Ho;Won, Doo-Hee;Lee, Kyung-Lak;Hong, Cheol;Do, Yuno
    • Korean Journal of Ecology and Environment
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    • v.55 no.1
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    • pp.76-83
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    • 2022
  • We attempted to estimate potential habitats of Clithon retropictus and to determine the community structure of benthic macroinvertebrates by presence of C. retropictus. 2016 to 2018 database of "Survey and Assessment of Estuary Ecosystem Health" by the Ministry of Environment were used to identify the distribution site of C. retropictus. The occupancy model was applied to estimate the potential habitat of C. retropictus. Four diversity indices were used to confirm the community structure of benthic macroinvertebrates. C. retropictus was found in the southern coast area and part of the east coast, and this pattern was consistent with previous studies. Additionally, the occupancy model predicted that a potential habitat of C. retropictus could appear in the west coast area. The community structure of benthic macroinvertebrates was relatively high at the site with C. retropictus than the site without C. retropictus. Therefore, the occupancy model can be considered when conserving C. retropictus inhabiting a limited area. Additionally, C. retropictus can be used to the indicator species that can represent the brackish water environment.

The Characteristics of Traditional Irrigation Farming System of Uiseong-gun (의성 전통수리 농업시스템의 특징)

  • Lee, Yoo-Jick;Lee, Seung-Hye;Lee, Da-Young;Jeong, Jae-Hyeon;Park, Jin-Wook;Gu, Jin Hyuk
    • Journal of Korean Society of Rural Planning
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    • v.29 no.1
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    • pp.69-79
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    • 2023
  • Uiseong-gun, Gyeongsangbuk-do, one of the representative small rain regions, has developed a traditional irrigation farming system while overcoming and adapting to unfavorable agricultural environments from the days of the ancient nation of Jomunguk to the present. In 2018, its value was recognized and designated as Nationally Important Agricultural Heritage System No. 10. This study was conducted with the purpose of examining the characteristics of the traditional irrigation farming system in Uiseong from the viewpoints of irrigation facilities, irrigation communities, and agricultural activities. The research results are as follows. Uiseong-gun has been expanding irrigation facilities for agriculture since long ago, and it has been investigated that a total of 6,227 irrigation facilities are currently distributed along the Wicheon water system that crosses Uiseong-gun from east to west. Irrigation facilities appear differently depending on the topography. The irrigation facility has a 'su-tong' as an irrigation passage and a corkscrew structure 'mot-tchong' as a water quantity control device, so the amount of water was adjusted as needed. Through this facility, surface water with warmer temperature is supplied to the farmland to prevent cold damage to crops. Uiseong has developed activities to organize irrigation communities in one village or several villages to secure agricultural water from an early age. Currently, this tradition continues, and a total of 213 irrigation communities manage 375 irrigation facilities (6.0% of all irrigation facilities). Through this organization, called Mong-ri-gye, water for agriculture is obtained, managed, and distributed equitably. In order to increase agricultural production, Uiseong implemented double cropping by converting rice fields and fields. In the case of Mt. Geumseong, double cropping of rice and barley was mainly carried out until the 1970s, but since the 1980s, double cropping of rice and garlic has been implemented with higher income. One of the unique features of the agricultural system of this region is the spectacular landscape that changes simultaneously from field to rice field in spring and from rice field to field in autumn.

The Geomorphological Characteristics of Coastal Dune in Young Gwang, Jeonnam (전남 영광 지역의 해안사구 지형 특성)

  • PARK, Cheol-Woong
    • Journal of The Geomorphological Association of Korea
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    • v.18 no.4
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    • pp.177-191
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    • 2011
  • This paper describes a dune field on shoreline of Young Gwang. To clarify geomorphic characteristics, made an analysis of grain size of the sand sediments samples and surface texture of quartz grains, and field survey. The following results were obtained : 1) Young Gwang sand dune is taking to pieces by human impact, and dose not move ahead the process of sand dune. 2) there was a turbulence of sand sediments outcrops saying to the cryoturbation that represents cold climatic environments, 3) Constituents of sand dune are mainly fine and very fine sand(2.5~4.5Φ) consisted by quartz and feldspar. Young Gwang sand grians have some analogy with different sites in west coast 4) In surface texture, roundness is thought to have been formed sub-angular, and some V cracks represented mechanical weathering environments. Especially, the dune environment has significant cultural and archaeological values arising from the occupation of human in the past. Those areas where occupation is known provide a valuable source of past records relating to human settlement.

Trust, relationship, and civil society in Scandinavia and East Asia: Psychological, social, and cultural analysis (북유럽과 동아시아에서의 신뢰, 관계와 시민 사회: 심리, 사회, 문화적 분석)

  • Uichol Kim ;Young-Shin Park
    • Korean Journal of Culture and Social Issue
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    • v.11 no.spc
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    • pp.133-161
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    • 2005
  • The present paper examines trust, interpersonal relationship, and civil society in Scandinavia and East Asia. In the first section, the concepts of trust and democracy are defined. In the second section, the cultural transformations that paved the way for the development of democracy in the West and Scandinavia are reviewed. In the third section, the basis of trust and democracy in East Asia, focusing on Confucianism, is reviewed. In the fourth section, a review of an empirical study conducted with a national sample in Denmark, Sweden, Japan, and Korea is presented. The results indicate that both the Scandinavian and East Asian respondents support the basic ideas of liberal democracy and trust close ingroup members. East Asian respondents are less likely than Scandinavian respondents to trust their colleagues and outgroup members and much less likely to trust political and government institutions. Scandinavian respondents prefer tolerant leaders who lead by ideas, while Koreans prefer strong paternalistic and moral leaders. Japanese respondents are less supportive of paternalistic leaders. Overall, results indicate that in Scandinavia and East Asia, although the basic ideas about democracy and human rights are similar, the methods of implementing these ideas are different. When compared with Scandinavia, there is much lower transparency and accountability in East Asia. In the final section, the challenges that the modern democracies face are discussed.

Analysis of the effect of improving human thermal environment by road directions and street tree planting patterns in summer (여름철 도로 방향과 가로수 식재 방식에 의한 인간 열환경 개선효과 분석)

  • Jeonghyeon Moon;Yuri Choi;Eunja Choi;Jueun Yang;Sookuk Park
    • Journal of the Korean Association of Geographic Information Studies
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    • v.27 no.2
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    • pp.1-18
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    • 2024
  • This study aimed to identify the optimal street tree planting method to improve the summer thermal environment in Seoul, Republic of Korea. The effects of road direction and street tree planting patterns on urban thermal environments using ENVI-met simulations were analyzed. The 68 scenarios were analyzed based on four road directions and 17 planting patterns. The results showed that tree planting had a reducing air temperature, mean radiant temperature, human thermal sensation (PET and UTCI). The most effective planting pattern among all scenarios was low tree height (6m), wide crown width (9m), high leaf area index (3.0), and narrow planting interval (8m). The largest improvement in the thermal environment was the northern sidewalk of the east-west road. Since this study used computer simulations, the difference from real urban spaces should be considered, and further research is needed through field measurement and consideration of more variables.

Establishment of Standard Methods for Marine Ecotoxicological Test (해양생태독성평가를 위한 표준시험방법 개발에 관한 연구)

  • Park, Gyung-Soo;Lee, Seung-Min;Han, Tae-Jun;Lee, Jung-Suk
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.13 no.2
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    • pp.106-111
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    • 2008
  • Six standard methods for marine ecotoxicological tests were established(or applicated) using marine decomposer, primary producers and consumers. Development processes referred to the standard methods established by USEPA(United States Environmental Protection Agency), international organizations and European methods. However, the standard test species were selected among the domestic species generally found in the Korean waters and sediments. The test methods provide the culture/maintenance of test species, test methods, reproducibility and quality acceptance criteria etc. A total of nine test species were designated including bioluminescent bacteria(Vibrio fischeri), diatom(Skeletonema costatum), seaweed(Ulva pertusa), rotifer(Brachionus plicatilis), benthic copepod(Tigriopus japonicus), benthic amphipods(Mandibulophoxus mai, Monocorophium acherusicum), and fishes(Oryzias latipes, Paralichthys olivaceus). These test species represent the decomposer, primary producer and consumers in marine trophic system in Korean coastal ecosystems, and we recommend the "battery test" including at least one species from the each trophic level for marine ecotoxicological test.

Development of Sediment Toxicity Test Protocols using Korean Indigenous Marine Benthic Amphipods (국내산 저서 단각류를 이용한 퇴적물 독성시험법 개발에 관한 연구)

  • Lee, Jung-Suk;Lee, Seung-Min;Park, Gyung-Soo
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.13 no.2
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    • pp.147-155
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    • 2008
  • A series of experiments were conducted to find standard test organisms and to develop test protocols for sediment toxicity tests using indigenous amphipods inhabited in Korean coastal environments. The indigenous amphipods Mandibulophoxus mai and Monocorophium acherusicum were well associated with various sediment substrates from sand to mud. The tolerance limits to various physico-chemical factors affecting bioassay results such as temperature, salinity and total ammonium as well as the sensitivities to contaminants in water and sediments were investigated using M. mai and M. acherusicum in the present study. These amphipods were tolerable to the adequate ranges of salinity ($10{\sim}30\;psu$), temperature ($10{\sim}25^{\circ}C$) and ammonia (<50 ppm). They have relevant sensitivities to the reference toxicants, dissolved cadmium as well as other metals and organic pollutants, when compared to the standard test species used in other countries. Field-sediment toxicity tests revealed that M. mai would be more sensitive to sediment-associated pollutants than M. acherusicum, while the sensitivity of M. acherusicum was comparable to those of other sediment test species in other countries. Overall results of this first attempt to develop an amphipod sediment toxicity test protocol in Korea indicated that M. mai and M. acherusicum should be applicable in the toxicity assessment of contaminated sediments, following the further evaluation encompassing various ecological and toxicological evaluation and the standardization of test method.

Development of Marine Toxicity Standard Method for Marine Luminescent Bacteria: Introduction of N-Tox test (해양성 발광박테리아를 이용한 해양환경 독성평가 시험법 개발: N-Tox test)

  • Lee, Kyu-Tae;Park, Gyung-Soo;Kim, Pyoung-Joong
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.13 no.2
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    • pp.156-163
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    • 2008
  • Luminescent bacterial toxicity test was first introduced in the early 1980s, registered as international standard method in 1998 and now widely used as a common toxicity test method. This toxicity test uses luminescent bacterium, Vibrio fischeri, originated from marine environment as a test organism. The degree of toxicity can be evaluated from the comparison of luminescent emission intensity between control and treatment groups to toxicants and materials from various environmental matrix for 30 min. This test can be carried out by using commercial products and its results are sensitive and precise. This research is on the feasibility of adopting luminescent bacterial test as a domestic standard test protocol. Using commercial products, a series of experiments were conducted to identify the precision and accuracy of injection volume and light emission, and to evaluate concentration-response relationship between chemical concentrations and light emissions. Also, the feasibility of the application to environmental media and quality assurance/quality control were checked. The results of serial toxicity tests revealed that the preliminary luminescent bacterial toxicity test was robust and suitable as a standard method.

Smartwork Application & Effects: Empirical Test for the Extended Work Design Theory (스마트워크 적용과 효과: 업무 설계 이론을 중심으로)

  • Hyejung Lee;Jun-Gi Park
    • Information Systems Review
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    • v.20 no.2
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    • pp.21-37
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    • 2018
  • Under ubiquitous work environment, innovative changes occur in work process with ICT. The work process for collaboration through mobile devices and network should be investigated. The research model consists of two major antecedents: autonomy and interdependence as a task characteristic and job satisfaction as ultimate consequence followed by work design theory. To elaborate work design theory, smartwork application (app) use, communication extent, and work-life balance were reviewed from the literature. Data were collected from three ICT firms, which adopted certain smartwork app, and a partial least squares analysis was made on 175 data points. The analysis results show that task interdependence exerts a statistically significant effect on the level of smartwork app usage. Communication extent directly affects job satisfaction and work-life balance. The remarkable point is that smartwork app usage does not affect employees' work-life balance; the former can only affect the latter indirectly by increasing communication extent. This study attempts to explain the organizational impact by considering smartwork app and the effects simultaneously. We proposed and empirically tested the extended work design theory including information technology and its environment. Based on the results, other theoretical and practical contributions are discussed at the end with limitations and further studies.