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Clozapine Administration Potentiate Platelet Activation in Patients with Schizophrenia : Retrospective Study (클로자핀을 투여한 조현병 환자에서 혈소판 활성 증가에 관한 후향적 연구)

  • Kim, Hyun-Ah;Lee, Jong Wook;Kim, Seung-Jun;Oh, Hong-Seok;Im, Woo Young;Kim, Ji-Woong
    • Korean Journal of Psychosomatic Medicine
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    • v.26 no.2
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    • pp.188-193
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    • 2018
  • Objectives : Clozapine is a widely prescribed antipsychotic drug for schizophrenia and is known to increase the risk of cardiovascular disease due to its metabolic side effects. However, little is known about the effect of clozapine on the platelet activation, another important factor in the development of cardiovascular disease. In this study, we tried to investigate the effect of clozapine on platelet activity in patients with schizophrenia by comparing the mean platelet component (MPC) values before and after the clozapine administration. Methods : A retrospective review of medical records of patients with schizophrenia, who newly started clozapine treatment from September 1st, 2003 to April 30th, 2007 at the Department of Psychiatry, Konyang University Hospital in Republic of Korea was performed. The final statistical analysis included 14 participants. Bayer ADVIA $120^{(R)}$ system was used to measure MPC. Results : Among the 14 participants, five subjects were males (28.60%), and ten subjects were females (71.40%). The mean age of participants was $37.50{\pm}11.64years$. Average of duration of illness was $91.00{\pm}93.96months$, with the mean dosage of clozapine taken by participants at the time of the last blood test was $337.50{\pm}109.52mg$. The mean MPC measurement before and after receiving clozapine was $26.12{\pm}2.22g/dL$ and $25.14{\pm}2.08g/dL$ respectively. Wilcoxon signed rank test showed that there was a statistically significant decrease in MPC levels after clozapine administration (V=16, p=0.024). Conclusions : Decreased MPC levels after clozapine administration implies that clozapine may increase platelet activation which could have an adverse effect on the occurrence of thromboembolic disease. Our findings also suggest that careful monitoring of the risk factors of cardiovascular diseases, such as platelets activity, is necessary when administering clozapine.

Evaluation of Standing Tree Characteristics by Development of the Criteria on Grading Hardwood Quality for Oaks Forests in Central Region of Korea (활엽수 입목형질등급 기준 개발을 통한 중부지역 참나무림의 입목특성 평가)

  • Lee, Young Geun;Lee, Sang Tae;Chung, Sang Hoon
    • Journal of Korean Society of Forest Science
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    • v.107 no.4
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    • pp.344-350
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    • 2018
  • This study was carried out to improve the forest management method considering the use of high value added timber in the natural broadleaf forests. For this purpose, the criteria for evaluating the quality grade of standing trees were established and applied to the oak stand in the central region of Korea. The evaluation factors of the grade were bending of stem, branch, stem damage, and other defects. If the logs are divided into 2.1 m units and three logs up to 6.3 m are available, they are classified as Grade I (G-I). If two logs are available, they are classified as Grade II (G-II), If only one log is available, it is classified as Grade III (G-III). When any log is not available as timber, it is classified as Grade IV (G-IV). As a result of applying the grade to the oak stand, G-I was 6.7 %, G-II was 28.0 %, G-III was 38.3 %, and G-IV was 27.0 %. The ratio of standing trees by oak species of higher than G-III was 88.2 % for Quercus acutissima, 88.1 % for Q. variabilis, 83.5 % for Q. serrata, 56.3 % for Q. aliena, and 50.3 % for Q. mongolica, respectively. The G-IV ratio for Q. variabilis and Q. mongolica tended to decrease with increasing diameter at breast height. The order of major defect affecting the grading level was bending of stem > branch > stem damage > other defects. Considering the grade level and oak species distribution, it was concluded possible to produce high quality hardwood timber when we concentrate forest tending techniques on Q. acutissima and Q. variabilis stand. In order to improve the accuracy of grading, it is necessary to continuous complement through the monitoring research for evaluation factors.

Effect of Land Use Change and Price from the Area Adjustment of National Park in Korea - A Case Study of Woraksan National Park - (국립공원 구역 조정이 토지이용 변화 및 가격에 끼친 영향 - 월악산국립공원을 중심으로 -)

  • Jeon, Kun Chul;Nam, Jin;Cho, Woo
    • Korean Journal of Environment and Ecology
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    • v.32 no.6
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    • pp.639-645
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    • 2018
  • The objective of the study is to analyze the impact of zone adjustment by comparing the changes from 2011 to 2018 of social and environmental factors such as the special-purpose area, actual construction activities including building development, land use environment, and officially assessed individual land price in the areas released from the National Park Zone during the second National Park Zone adjustment during 2010 to 2011 with the social and environmental factors in the areas that remained in the National Park Zone during the same period. We intended to investigate the problems of the second National Park Zone adjustment and explore alternative implications for the third National Park Zone adjustment. As for the special-purpose area, 80.4% of the released areas were converted to planned, production, and conservation area while 15.6% changed to the agricultural area, and 4.0% remained as the natural environmental conservation area. Regarding the change in building development scale, the average size of construction in the released area since 2011 was $106m^2$ while that in the retained areas was $91m^2$. For the land use environment, the rate of change from the natural area to developed area was 1.9% in the released area and 0.7% in the retained area. The officially assessed individual land price increased by 11,911 won in the released area and 4,413 won in the retained area. Although both areas showed an increase in the land price, the difference of officially assessed individual land prices was about 2.5 times. The problem concerning the private property rights of local residents in the national parks is still a challenge, but the second National Park Zone adjustment has resolved the problem significantly. Accordingly, it is necessary to offer the benefits for the residents in the national park area by analyzing the park zoning and park facility planning to present the rational alternative. It is also necessary to establish a support system that encourages the collaborative cooperation between the park authority and residents and assures that the residents to have pride in the national park.

An essay on appraisal method over official administration records ill-balanced. -For development of appraisal process and method over chosun government-general office records- (불균형 잔존 행정기록의 평가방법 시론 - 조선총독부 공문서의 평가절차론 수립을 위하여 -)

  • Kim, Ik-Han
    • The Korean Journal of Archival Studies
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    • no.13
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    • pp.179-203
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    • 2006
  • This study develops the process and method of official administration documents which have remained ill-balanced like the official documents of the government-general of Chosun(the pro-Japanese colonial government (1910-1945)). At first, the existing Appraisal-theories are recomposed. The Appraisal-Theories of Schellenberg is focused valuation about value of records itself, but fuction-Appraisal theory is attached importance to operational activities which take the record into action. But given that the record is a re-presentation of operational activities, the both are the same on the philosophy aspect. Therefore, in the case that the process - method is properly designed, it can be possible to use a composite type between operational activities and records. Also, a method of the Curve has its strong points in the macro and balanced aspect while the Absolute has it's strength in the micro aspect, so that chances are that both alternate methodologies are applied to the study. Hereby, the existing Appraisal theories are concluded to be the mutually-complemented things that can be easily put together into various forms according to the characteristics of an object and its situation, in the terms of the specific Appraisal methodology. Especially, in the case of this article dealing with the imbalance remains official-documents, it is necessary to compromise more properly process with a indicated useful method than establishing a method and process by choosing the only one theory. In order to appraise the official-documents of the pro-Japanese colonial government (1910-1945), a macro appraisal of value has to be appraised about them by understanding a system, functions and using the historical-cultural evolution, after analysing Disposal Authority. From this, map the record so that organization function maps are constructed regarding the value rank of functions and detailed-functions. After this, establish the appraisal strategy considering the internal environment of archival agencies and based on micro appraisal to a great quantity of records remained and supplying other meaning to a small quantity of records remained for example, the oral resources production are accomplished. The study has not yet reached the following aspects ; a function analysis, historical decoding techniques, a curve valuation of the record, the official gazette of the government general of Chosun( the pro-Japanese government for 1910-1945), an analysis method of the other historical materials and it's process, presentation of appraisal output image. As the result, that's just simply a proposal and we should fill in the above-mentioned shortages of the study through development of all the up-coming studies.

Do Women's Attitude to Domestic Works and Self-perception of Social Norms Enforce the Gender Division of Housework? - Analysis of Mediation Effects Using the Theory of Reasoned Action - (여성의 가사노동에 대한 태도 및 사회적 규범에 대한 여성의 인식이 가사노동시간의 성불평등에 영향을 미치는가?: 합리적 행위이론을 통한 매개효과 분석)

  • Lee, Seungju;Lee, Somin
    • Korean Journal of Family Social Work
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    • no.58
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    • pp.5-36
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    • 2017
  • This study aims to empirically analyze whether the women's cognitive attitude toward gender role, which is formed through social norms, enforces the gender division of housework. In this study, 4,435 married women aged 18-59 years from the 5th wave dataset of Korean Longutudinal Survey of Women and Family Data were selected for analysis. Using the Structural Equation Model(SEM), we examine the direct effect of "attitude toward behavior" and "subjective norm" on the domestic working hours and whether those two independent variables, such as "attitude toward behavior" and "subjective norm," influence the mediator variable "Behavior Intention" which in turn affect the dependent variable. The study reveals that "attitude toward the gender division of housework" has a statistically significant direct effect on the domestic working hours as well as an indirect effect operating through "behavior intention." And"subjective norm "has only a statistically significant indirect effect on the domestic working hours, operating through "behavior intention." Despite the fact that many women are now aware that various work-life balance policies are avaliable to mitigate the gender inequality of domestic works, it is proven that the gender division of housework becomes worse. The reason behind this is not only because there exist some problems in implementing the institutions themselves, but also because women's deeply internalized self-perception of gender role based on the traditional patriarchal culture somehow exacerbates the gender division of housework. Hence, in order to instill a progressive change in gender division of housework, it is important for women to try to change the way they perceive the stereotypical gender roles as well as for men to treat women equally.

Comparison of Educators and Students' Perception of Evaluation Criteria for Admission to Career and Technical High Schools: A Case Study (특성화고등학교 미래인재전형의 평가기준에 대한 교사와 학생의 인식비교 : 서울시교육청 특성화고 사례를 중심으로)

  • Cho, Sung Ran;Lee, Hwa-Yeong;Han, jiyoon;Ye, Cheol-Hae;Shin, Changho
    • (The)Korea Educational Review
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    • v.24 no.1
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    • pp.227-254
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    • 2018
  • This study examines differences in perception between applicants and admissions committee members regarding evaluation criteria for admission to career and technical high schools in Seoul. This investigation, based on "The survey on policy for career and technical high school admissions," seeks to explore and consider the various criteria for selecting and evaluating students. The target populations of the survey were the educators in charge of admission and freshmen in Seoul career and technical high schools. We report three major findings, with the first pertaining to the existing criteria and policies for admission to career and technical high schools. While educators agreed with the intent and reasoning behind the school's competitive spots, they were overall dissatisfied with the selection method and the lack of a requirement for academic transcripts. Matriculated students, in comparison, expressed greater satisfaction with the existing criteria for admission. Secondly, when assessing the importance of various evaluation components in an application, educators viewed the interview and attendance record as the most valuable components of the application, followed by future plans, personal statement, volunteer work, and portfolio, in order of decreasing importance. Students ranked attendance record, interview, personal statement, portfolio, future plans, and volunteer work as most to least important components of their application. Thus, students regarded the personal statement and portfolios as being of higher priority than did the educators. The last major finding pertained to students' rationale for applying and educators' selection criteria. At the time of application, students focused on aptitude and job prospects after graduation, while educators valued personality and competence. In summary, the applicants' viewpoints and actions aligned much more closely with the mission of the Seoul Metropolitan Office of Education than did those of the educators in charge of admission. Thus, in order to establish a consensus between the policy and mission of career and technical high schools, each career and technical high school should clarify the exact criteria for their ideal candidate. There is also a need to bridge the gap in perception between the applicants and educators regarding selection strategy, to establish a harmonized evaluation criteria. These goals are necessary to attract and recruit talented, bright individuals who will meet the demands of today's society.

Development and Characterization of Rice Lines with Clustered Spikelets and Dense Panicles (군집소수를 가진 고착립밀도 이삭형 벼 개발 및 특성 분석)

  • Park, Hyun-Su;Baek, Man-Kee;Kim, Choon-Song;Lee, Gun-Mi;Park, Seul-Gi;Lee, Chang-Min;Suh, Jung-Pil;Cho, Young-Chan
    • Korean Journal of Breeding Science
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    • v.50 no.4
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    • pp.415-423
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    • 2018
  • Rice panicle architecture is an important factor affecting yield potential. Korean rice cultivars have a narrow genetic background for panicle architecture. To enhance the yield potential of Korean rice cultivars, we developed and characterized rice lines with new panicle architecture. Rice with improved panicle architecture has clustered spikelets and dense panicles (CD type). CD rice was derived from a cross between "Binhae Col.#1" carrying dense panicles, and "ARC10319" that has the clustered spikelets gene (Cl). CD rice lines had short and semi-erect panicles with two to five high density spikelets clustered at the tips of primary and secondary rachis branches. CD rice lines had dramatically increased numbers of spikelets; almost twice as many as those of Korean rice cultivars. The increase in spikelet number was mainly caused by the increased spikelets and branches on secondary rachises compared to those on primary rachises. The increase in spikelet number was expected to enhance the yield of CD rice by expanding sink capacity. However, the yield of selected lines; CD9, CD27, CD34, and CD39, did not reach the level of the Korean high-yielding cultivars "Boramchan" and "Hanareum2," due to the reduction in panicle number and grain weight, and poor ripening. Although no substantial yield increase was observed in CD rice, the panicle architecture of CD rice, clustered spikelets, and dense panicles could be new genetic resources as breeding material for diversifying panicle architecture and enhancing yield potential.

A Review on Monitoring Mt. Baekdu Volcano Using Space-based Remote Sensing Observations (인공위성 원격탐사를 이용한 백두산 화산 감시 연구 리뷰)

  • Hong, Sang-Hoon;Jang, Min-Jung;Jung, Seong-Woo;Park, Seo-Woo
    • Korean Journal of Remote Sensing
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    • v.34 no.6_4
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    • pp.1503-1517
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    • 2018
  • Mt. Baekdu is a stratovolcano located at the border between China and North Korea and is known to have formed through its differentiation stage after the Oligocene epoch in the Cenozoic era. There has been a growing interest in the magma re-activity of Mt. Baekdu volcano since 2010. Several research projects have been conducted by government such as Korea Meteorological Administration and Korea Institute of Geoscience and Mineral Resources. Because, however, the Mt. Baekdu volcano is located far from South Korea, it is quite difficult to collect in-situ observations by terrestrial equipment. Remote sensing is a science to analyze and interpret information without direct physical contact with a target object. Various types of platform such as automobile, unmanned aerial vehicle, aircraft and satellite can be used for carrying a payload. In the past several decades, numerous volcanic studies have been conducted by remotely sensed observations using wide spectrum of wavelength channels in electromagnetic waves. In particular, radar remote sensing has been widely used for volcano monitoring in that microwave channel can gather surface's information without less limitation like day and night or weather condition. Radar interferometric technique which utilized phase information of radar signal enables to estimate surface displacement such as volcano, earthquake, ground subsidence or glacial movement, etc. In 2018, long-term research project for collaborative observation for Mt. Baekdu volcano between Korea and China were selected by Korea government. A volcanic specialized research center has been established by the selected project. The purpose of this paper is to introduce about remote sensing techniques for volcano monitoring and to review selected studies with remote sensing techniques to monitor Mt. Baekdu volcano. The acquisition status of the archived observations of six synthetic aperture radar satellites which are in orbit now was investigated for application of radar interferometry to monitor Mt. Baekdu volcano. We will conduct a time-series analysis using collected synthetic aperture radar images.

The Process of Overcoming Prejudice and Discrimination Experiences of Mothers with Disabilities (장애아동 어머니가 겪는 편견 및 차별경험 극복과정)

  • Oh, Yeon Soo
    • The Journal of the Korea Contents Association
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    • v.19 no.2
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    • pp.477-490
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    • 2019
  • This study analyzes the process of overcoming prejudice and discrimination experiences of mothers with disabilities and looks for improvement points. It is interviewed 9 mothers of children with disabilities who were experiencing prejudice and discrimination while raising children with disabilities. The data collection was conducted from October to November, 2018 and one by on one in depth interview by using semi - structured questionnaires. Data analysis was done through consensual qualitative research (CQR). The result of CQR while it is a experiencing the process of prejudice and discrimination as well as coping the raising disabled children. 'Prejudice and discrimination experience of mothers with disabilities' and 'overcoming of discrimination experiences of mothers with disabilities' were derived. And the seven sub-regions, 28 categories, were finally constructed. The results of the study are as follows. Firstly, Prejudice and discrimination experiences of mothers with disabilities in raising children with disabilities are view of looking at children with disabilities comparing to those of normal children and children with disabilities. It seems that they want to treat the disabled child as the general child with an attitude of understanding and accepting the disabled child rather than looking at the disabled child with wrong perception, prejudice, stereotypes and rejection. Secondly, The process of overcoming the discrimination experiences of the mother of the disabled child is strengthening the cohesion and cohesion within the family in the process of accepting and coping with the disability family of the child with disabilities even if they raise the child with disability and have difficulties such as recognition bias and discrimination of the general public. Based on the results of this study, we suggested practical and policy implications for the mother's psychological stability of the child with disability and the disabled child's healthy life.

A Study on Smart Accuracy Control System based on Augmented Reality and Portable Measurement Device for Shipbuilding (조선소 블록 정도관리를 위한 경량화 측정 장비 및 증강현실 기반의 스마트 정도관리 시스템 개발)

  • Nam, Byeong-Wook;Lee, Kyung-Ho;Lee, Won-Hyuk;Lee, Jae-Duck;Hwang, Ho-Jin
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.32 no.1
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    • pp.65-73
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    • 2019
  • In order to increase the production efficiency of the ship and shorten the production cycle, it is important to evaluate the accuracy of the ship components efficiently during the drying cycle. The accuracy control of the block is important for shortening the ship process, reducing the cost, and improving the accuracy of the ship. Some systems have been developed and used mainly in large shipyards, but in some cases, they are measured and managed using conventional measuring instruments such as tape measure and beam, optical instruments as optical equipment, In order to perform accuracy control, these tools and equipment as well as equipment for recording measurement data and paper drawings for measuring the measurement position are inevitably combined. The measured results are managed by the accuracy control system through manual input or recording device. In this case, the measurement result is influenced by the work environment and the skill level of the worker. Also, in the measurement result management side, there are a human error about the lack of the measurement result creation, the lack of the management sheet management, And costs are lost in terms of efficiency due to consumption. The purpose of this study is to improve the working environment in the existing accuracy management process by using the augmented reality technology to visualize the measurement information on the actual block and to obtain the measurement information And a smart management system based on augmented reality that can effectively manage the accuracy management data through interworking with measurement equipment. We confirmed the applicability of the proposed system to the accuracy control through the prototype implementation.