• Structural Engineering and Mechanics
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• 제65권3호
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• pp.233-241
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• 2018

In this paper, the Colliding Bodies Optimization (CBO), Enhanced Colliding Bodies Optimization (ECBO) and Vibrating Particles System (VPS) algorithms and the force method are used for the simultaneous analysis and design of truss structures. The presented technique is applied to the design and analysis of some planer and spatial trusses. An efficient method is introduced using the CBO, ECBO and VPS to design trusses having members of prescribed stress ratios. Finally, the minimum weight design of truss structures is formulated using the CBO, ECBO and VPS algorithms and applied to some benchmark problems from literature. These problems have been designed by using displacement method as analyzer, and here these are solved for the first time using the force method. The accuracy and efficiency of the presented method is examined by comparing the resulting design parameters and structural weight with those of other existing methods.

• Earthquakes and Structures
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• 제12권4호
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• pp.389-395
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• 2017

In this paper a simple approach is presented for spectral matching of ground motions utilizing the wavelet transform and a recently developed metaheuristic optimization technique. For this purpose, wavelet transform is used to decompose the original ground motions to several levels, where each level covers a special range of frequency, and then each level is multiplied by a variable. Subsequently, the vibrating particles system (VPS) algorithm is employed to calculate the variables such that the error between the response and target spectra is minimized. The application of the proposed method is illustrated through modifying 12 sets of ground motions. The results achieved by this method demonstrate its capability in solving the problem. The outcomes of the VPS algorithm are compared to those of the standard colliding bodies optimization (CBO) to illustrate the importance of the enhancement of the algorithm.

• The Journal of Advanced Prosthodontics
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• 제1권2호
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• pp.63-67
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• 2009

STATEMENT OF PROBLEM. Use of custom tray and tray adhesive is clinically recommended for elastomeric impression material. However there is not clear mention of drying time of tray adhesive in achieving appropriate bonding strength of tray material and impression material. PURPOSE. This study is to investigate an appropriate drying time of tray adhesives by evaluating tensile bonding strength between two types of polyvinylsiloxane impression materials and resin tray, according to various drying time intervals of tray adhesives, and with different manufacturing company combination of impression material and tray adhesive. MATERIAL AND METHODS. Adhesives used in this study were Silfix (Dentsply Caulk, Milford, Del, USA) and VPS Tray Adhesive (3M ESPE, Seefeld, Germany) and impression materials were Aquasil Ultra (monophase regular set, Dentsply Caulk, Milford, Del, USA) and Imprint II Garant (regular body, 3M ESPE, Seefeld, Germany). They were used combinations from the same manufacture and exchanged combinations of the two. The drying time was designed to air dry, 5 minutes, 10 minutes, 15 minutes, 20 minutes, and 25 minutes. Total 240 of test specimens were prepared by auto-polymerizing tray material(Instant Tray Mix, Lang, Wheeling, Il, USA) with 10 specimens in each group. The specimens were placed in the Universal Testing machine (Instron, model 3366, Instron Corp, University avenue, Nowood, MA, USA) to perform the tensile test (cross head speed 5 mm/min). The statistically efficient drying time was evaluated through ANOVA and Scheffe test. All the tests were performed at 95% confidence level. RESULTS. The results revealed that at least 10 minutes is needed for Silfix-Aquasil, and 15 minutes for VPS Tray Adhesive-Imprint II, to attain an appropriate tensile bonding strength. VPS Tray Adhesive-Imprint II had a superior tensile bonding strength when compared to Silfix-Aquasil over 15 minutes. Silfix-Aquasil had a superior bonding strength to VPS Tray Adhesive-Aquasil, and VPS Tray Adhesive-Imprint II had a superior tensile bonding strength to Silfix-Imprint II at all drying periods. CONCLUSION. Significant increase in tensile bonding strength with Silfix-Aquasil and VPS Tray adhesive-Imprint II combination until 10 and 15 minutes respectively. Tray adhesive-impression material combination from the same company presented higher tensile bonding strength at all drying time intervals than when using tray adhesive-impression material of different manufactures.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제19권2호
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• pp.117-119
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• 2017

There are a number of complications associated with ventriculoperitoneal shunt (VPS) surgery. The authors present a rare case of iatrogenic common carotid artery injury during VPS surgery.

• 디지털산업정보학회논문지
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• 제6권3호
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• pp.191-201
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• 2010

The Korean central government has been investing a lot of efforts to promote performance of local governments. For example, the Ministry of Public Administration and Security (MOPAS) supported the local governments to develop and provide with a 'balanced score card' and a 'customer satisfaction innovation. ' Many other central ministries also conducted individual evaluations for local governments in their substantive policy areas. These evaluation systems of 78 appraisals for local governments conducted by the MOPAS and other ministries had made the local governments to work harder. However, most local governments have appealed their 'reform fatigue' caused by the overlapping evaluation systems. In this context, the MOPAS initiated merging the evaluations into a co-evaluation system under the new Government Performance Evaluation Act of 2006. In this process of introduction of new evaluation system, there are two significant movements. Firstly, as Korean Government has strong information technology, MOPAS has developed 'Virtual Policy Studio (VPS)' which evaluates the performance of each local government with on line. In other words, in the co-evaluation system for local government performance most evaluation steps are implemented by computer and Internet. So most stakeholder can access and work on the VPS in real time when they want to. And the other thing is that cooperation among stakeholders has been occurred in the co-evaluation system. Furthurmore the cooperative governance is systemized and sustain for a long time because MOPAS made IT based co-evaluation system. Therefore this paper intends to illustrate the process of introduction of VPS, main process of co-evaluation system based on VPS and analyze collaborative governance of the co-evaluation system.

• Genomics & Informatics
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• 제19권4호
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• pp.39.1-39.8
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• 2021

Tamoxifen (TAM) is an anticancer drug used to treat estrogen receptor (ER)-positive breast cancer. However, its ER-independent cytotoxic and antifungal activities have prompted debates on its mechanism of action. To achieve a better understanding of the ER-independent antifungal action mechanisms of TAM, we systematically identified TAM-sensitive genes through microarray screening of the heterozygous gene deletion library in fission yeast (Schizosaccharomyces pombe). Secondary confirmation was followed by a spotting assay, finally yielding 13 TAM-sensitive genes under the drug-induced haploinsufficient condition. For these 13 TAM-sensitive genes, we conducted a comparative analysis of their Gene Ontology (GO) 'biological process' terms identified from other genome-wide screenings of the budding yeast deletion library and the MCF7 breast cancer cell line. Several TAM-sensitive genes overlapped between the yeast strains and MCF7 in GO terms including 'cell cycle' (cdc2, rik1, pas1, and leo1), 'signaling' (sck2, oga1, and cki3), and 'vesicle-mediated transport' (SPCC126.08c, vps54, sec72, and tvp15), suggesting their roles in the ER-independent cytotoxic effects of TAM. We recently reported that the cki3 gene with the 'signaling' GO term was related to the ER-independent antifungal action mechanisms of TAM in yeast. In this study, we report that haploinsufficiency of the essential vps54 gene, which encodes the GARP complex subunit, significantly aggravated TAM sensitivity and led to an enlarged vesicle structure in comparison with the SP286 control strain. These results strongly suggest that the vesicle-mediated transport process might be another action mechanism of the ER-independent antifungal or cytotoxic effects of TAM.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.237.2-237.2
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• 2016

A pure hafnium-carbide (HfC) coating layer was deposited onto carbon/carbon (C.C) composites using a vacuum plasma spray system. By adopting a SiC buffer layer, we successfully integrated C.C composites with a $100-{\mu}m-thick$ protective coating layer of HfC. Compared to the conventional chemical vapor deposition process, the HfC coating process by VPS showed increased growth rate, thickness, and hardness. The growth behavior and morphology of HfC coatings were investigated by FE-SEM, EDX, and XRD. From these results, it was shown that the addition of a SiC intermediate layer provided optimal surface conditions during the VPS procedure to enhance adhesion between C.C and HfC (without delamination). The thermal ablation test results shows that the HfC coating layer perfectly protected inner C.C layer from thermal ablation and oxidation. Consequently, we expect that this ultra-high temperature ceramic coating method, and the subsequent microstructure that it creates, can be widely applied to improve the thermal shock and oxidation resistance of materials under ultra-high temperature environments.

• 대한화장품학회지
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• 제45권4호
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• pp.373-380
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• 2019

얼굴과 하박내측의 피부는 경피수분손실량(TEWL), 피부 수분량, 탄력 등에서 많은 차이를 보이고 있다. 특히, 이전 연구 결과에서 얼굴피부와 하박내측 피부는 수화(hydrating) 과정에 따른 탄력특성의 차이를 보여 주었다. 이에 본 연구에서는 신체부위에 따른 피부특성 차이는 각 신체부위를 구성하고 있는 각질세포 특성과 연관성이 있을 것이라는 가정하에 atomic force microscopy (AFM)을 이용하여 각질세포 표면 특성을 비교 연구하였다. 각질세포 표면의 거칠기(roughness)와 villus-like projections (VPs)을 이용하여 비교 평가 하였다. 더 나아가 얼굴피부, 하박내측, 입술 피부의 각질세포 표면을 정성적으로 비교해 보았다. 각질세포는 8명의 피험자의 얼굴과 하박내측 피부에서 tape-stripping을 이용하여 채취하여, AFM을 이용하여 40 ㎛ × 40 ㎛ 크기로 각질세포의 아랫면 표면 특성(bottom surface of corneocyte)을 측정하였다. 그 결과, 얼굴 각질세포 아랫면 표면 거칠기는 388.34 ± 86.189 nm이었고, 하박내측 각질세포 아랫면 표면 거칠기는 662.27 ± 224.257 nm로 하박내측 각질세포가 얼굴 각질세포보다 더 거친 표면 특성임을 확인하였다(p < 0.001). 관찰된 VPs의 양을 비교해보면, 입술 각질세포가 가장 많았고, 그 다음이 얼굴 각질세포이며, 하박내측 각질세포는 낮은 수준이었다. 이러한 결과를 통해 볼때, 각질세포 표면 특성이 얼굴과 하박내측 피부 사이에 보이는 특성 차이에 어느 정도 관여하고 있음을 확인할 수 있었으며, VPs는 부위별 피부 특성 연구에 유용한 parameter가 될 수 있는 가능성도 확인할 수 있었다. 그리고, AFM은 각질세포 표면의 미세한 구조적 차이를 비교 연구하는데 매우 유용한 기기임을 알 수 있었다. 향후 조금 더 많은 연구가 진행된다면 각질세포에 대한 새로운 화장품 효능 평가법이 개발될 것으로 사료된다.

• Journal of Korean Neurosurgical Society
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• 제60권1호
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• pp.1-7
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• 2017

Objective : The diagnosis of shunt malfunction can be challenging since neuroimaging results are not always correlated with clinical outcomes. The purpose of this study was to evaluate the efficacy of a simple, minimally invasive cerebrospinal fluid (CSF) lumbar tapping test that predicts shunt under-drainage in hydrocephalus patients. Methods : We retrospectively reviewed the clinical and radiological features of 48 patients who underwent routine CSF lumbar tapping after ventriculoperitoneal shunt (VPS) operation using a programmable shunting device. We compared shunt valve opening pressure and CSF lumbar tapping pressure to check under-drainage. Results : The mean pressure difference between valve opening pressure and CSF lumbar tapping pressure of all patients were $2.21{\pm}24.57mmH_2O$. The frequency of CSF lumbar tapping was $2.06{\pm}1.26times$. Eighty five times lumbar tapping of 41 patients showed that their VPS function was normal which was consistent with clinical improvement and decreased ventricle size on computed tomography scan. The mean pressure difference in these patients was $-3.69{\pm}19.20mmH_2O$. The mean frequency of CSF lumbar tapping was $2.07{\pm}1.25times$. Fourteen cases of 10 patients revealed suspected VPS malfunction which were consistent with radiological results and clinical symptoms, defined as changes in ventricle size and no clinical improvement. The mean pressure difference was $38.07{\pm}23.58mmH_2O$. The mean frequency of CSF lumbar tapping was $1.44{\pm}1.01times$. Pressure difference greater than $35mmH_2O$ was shown in 2.35% of the normal VPS function group (2 of 85) whereas it was shown in 64.29% of the suspected VPS malfunction group (9 of 14). The difference was statistically significant (p=0.000001). Among 10 patients with under-drainage, 5 patients underwent shunt revision. The causes of the shunt malfunction included 3 cases of proximal occlusion and 2 cases of distal obstruction and valve malfunction. Conclusion : Under-drainage of CSF should be suspected if CSF lumbar tapping pressure is $35mmH_2O$ higher than the valve opening pressure and shunt malfunction evaluation or adjustment of the valve opening pressure should be made.

• 한국구조물진단유지관리공학회 논문집
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• 제25권1호
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• pp.7-15
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• 2021

이 연구에서는 기존 중공재의 형상을 개선한 거푸집용 중공슬래브를 개발하였고, 개발된 VPS를 활용하여 휨 및 전단 실험을 수행하여 그 성능을 평가하였다. VPS의 휨 성능 실험 결과, FPS 계열 실험체의 경우 항복 하중 값은 FPS-00 실험체 대비 약 97.5%를 나타내고 있어 항복하중 값에는 큰 차이가 없는 것으로 나타났다. 또한, FNS계열 실험체도 FPS-00 실험체 대비 약 97%를 나타내어 휨 성능에는 중공재에 의한 영향이 거의 없는 것으로 나타났다. 따라서 슬래브 시스템을 VPS로 슬래브 설계에 적용할 때 건축구조기준의 설계식으로 적용하는데 문제가 없을 것으로 판단된다. VPS의 전단 성능 실험 결과, SS-00 실험체 대비 약 92%로 나타나 SS-00 실험체에 비하여 다소 부족한 것으로 나타났다. 이는 전단강도 식이 콘크리트에 의한 전단력과 철근에 의한 전단력의 합으로 표현되는 설계 식에 따라 중공재에 의하여 콘크리트 단면이 삭제되었기 때문인 것으로 판단된다. 하지만, 휨설계와 동일하게 전단설계에 적용되는 구조체의 내력도 최대하중 값을 기준으로 하는 것이 아니라 항복 하중 값을 기준으로 설계에 적용하게 된다.