• 대한의용생체공학회:의공학회지
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• 제28권3호
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• pp.317-324
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• 2007

The application of diffusion tensor imaging (DTI) and fiber tractography to Wallerian degeneration (WD) is important because this technique is a very potent tools for quantitatively evaluating fiber tracts in vivo brain. We analyzed a case and control using tracts of interest (TOI) analysis to quantify WD. We scanned a case of old infarction and an age-matched healthy volunteer. T1 magnetization prepared rapid acquisition gradient echo (MPRAGE), fluid attenuated inversion recovery (FLAIR) and 12-direction diffusion tensor imaging (DTI) were obtained and analyzed using TOI analysis. The value of mean diffusity ($D_{av}$) and fracional anisotrophy (FA) were analyzed statistically by MWU test. A p-value of less than 0.05 was considered to indicate statistical significance. A comparison of the global fiber diffusion characteristics shows WD of both the corpus callosum and the ipsilateral superior longitudinal fasciculus. The corpus callosum in particular showed trans-hemispherical degeneration. Local fiber characteristics along the geodesic paths show WD in the corpus callosum, ipsilateral superior longitudinal fasciculus, ipsilateral corticospinal tract, and ipsilateral corticothalamic tract. We have demonstrated changes in $D_{av}$ and FA values and a clear correspondence with the WD in various tracts. TOI analysis successfully revealed radial WD in white matter tracts from a region of encephalomalacia and primary gliosis, although they were only slightly affected.

• 가정과삶의질연구
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• 제30권4호
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• pp.119-132
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• 2012

The purpose of this study was to investigate the differences in time use between Korean and American high school students. The data sources were the '2009 Time Use Survey' conducted by Korea National Statistical Office and the '2009 ATUS (American Time Use Survey)' conducted by Labor Statistics Division in the U.S.. 1,734 Korean diaries (1,311 on weekdays and 423 on Sundays) and 321 American diaries (208 on weekdays and 113 on Sundays) from high school students of 15 to 18 years of age were analyzed. Descriptive statistics and t-test were used for the statistical analysis. The time use patterns of Korean students on weekdays and Sundays were different than those of their American counterparts. On weekdays and Sundays, the sleeping time of Korean students was 2 hours less than the time of their American counterparts. Koreans studied more, nearly double the time of their American counterparts on weekdays and five times more on Sundays. The study-oriented time allocation of Korean students resulted in less leisure time than the American students. Korean students spent their leisure time of more than 30 minutes participating in social activities, media, and hobbies, and their time allocation to volunteer work and religious activities were nil. On Sundays, the time for studying by Korean students was more than five times longer than that spending by their American counterparts. Koreans used their leisure time of 6 hours and 47 minutes mainly for media, hobbies and social activities. The participation rate of volunteering by Korean students was only 0.5%, though it was 31.0% for the Americans. For a study-life balance for Korean students, it was recommended that trends toward time management and social policy should increase the time allocation to sleeping, housework, work, sports, and volunteering and decrease the time use in studying and hobbies.

• 한국임상약학회지
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• 제5권2호
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• pp.51-60
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• 1995

Obesity is defined as excessive storage of energy in the form of fat resulting in adverse effect on healthy and longevity. Some data have shown increased incidence of hypertension, diabetes, hypercholesterolemia in overweight individuals and other disorders such as joint disease, cancer have been also associated with obesity. Recently, various commercial diet programs have been introduced for weight reduction without scientific evaluation for clinical effect and safety. The diet program must be based on a sound and scientific rationale and also be safe and nutritionally adequate. Pulmuone $diet^{(R)}$ is a calorie-restricted commercial diet-food, which contains adequate nutritients. The efficacy and safety of Pulmuone diet were evaluated in 28 normal healthy obese females in a prospective study. Each volunteer was placed in 3-week diet program. To observe weight reduction effect, body weight, TSF and AMC were measured every week. To account for safety of this program, blood chemistry test, blood pressure and side effects were monitored every week. Mean body weight was reduced by 3.24kg following diet program, which is statistically significant(P < 0.05) and this weight reduction was related to reduction in fat weight and not muscle weight as shown by the results of TSF and AMC Blood chemistry was not influenced by this program, but blood pressure was significantly reduced following this program. Thought diet program was generally well tolerated in most volunteers, the most frequent side effects are constipation, dizzness and headache. In conclusion, Pulmuone $diet^{(R)}$ program seems to be safe and effective for weight reduction in normal healthy obese females.

• 정보교육학회논문지
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• 제21권2호
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• pp.219-230
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• 2017

본 연구는 초등학생의 컴퓨팅 사고력 향상을 위한 교육 방법으로 스프레드시트를 활용한 데이터 과학 교육프로그램을 개발하여 적용한 후 그 효과를 검증하였다. 교육 프로그램은 Rossett의 요구 분석 모형을 적용하여 초등학생 205명과 컴퓨터교육 전공 현직 초등교사 20명을 대상으로 실시한 사전 요구분석 결과를 바탕으로, 교수설계의 대표 모형인 ADDIE 모형의 절차에 따라 개발하였다. 개발한 교육 프로그램의 효과를 검증하기 위해 ${\bigcirc}{\bigcirc}$대학교에서 실시한 교육기부 프로그램의 지원자 표집에 의한 지원자 표본 20명의 학생을 대상으로 총 6일 동안 42차시 수업을 진행하였고 사전 사후 검사 결과를 통해 교육적 효과를 분석하였다. 분석 결과, 본 연구에서 개발한 교육 프로그램이 초등학생의 컴퓨팅 사고력 향상에 효과적임을 알 수 있었다.

• 대한족부족관절학회지
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• 제21권4호
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• pp.156-164
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• 2017

Purpose: Foot and ankle disease (FAD) is a frequent cause of morbidity among the homeless population. Various conditions, exacerbated by malnutrition, poor lifestyle habits, psychiatric disorders, physical injuries, poor hygiene, and limited access to healthcare, have been described in this population. The purpose of this study was to investigate the cognition and management status of FAD in shelter based homeless people. Materials and Methods: Fifty-two male and twenty-five female volunteer homeless individuals were recruited from two homeless shelters. Each person completed a questionnaire assessing any presence of pain, pain management, as well as foot and ankle care status. A foot and ankle surgeon examined the physical status of the individual's foot and ankle, including tenderness and instability. A radiologic evaluation was done for 18 male and 11 female homeless people who agreed to participate in this test for the existence osteophyte or joint space narrowing representing osteoarthritis and some reference angles for hallux valgus, flatfoot and cavus foot. Results: Homeless people had higher prevalence of body mass index, diabetes, and smoking than the general population. The most prevalent infectious disease was fungal infection (male 78%, female 68%), with a low compliance of management for FAD. Conclusion: Although most of shelter-based homeless people showed an acceptable foot and ankle management status, the potential risk for FAD development and exacerbation of mild FAD was high.

• 한국지역사회생활과학회지
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• 제25권3호
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• pp.349-361
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• 2014

This study was examined the general trends in social activity participation, the flow degree, and the psychological well-being of middle-aged women in Korea and explored how psychological well-being varies according to various sociodemographic variables, social activity participation, and the flow degree. This study provided practical insights into how the psychological well-being of middle-aged women can be enhanced. Data were gathered from 302 middle-aged women between the ages of 40 and 60 by using a structural questionnaire. The statistical methods included a descriptive analysis, a t-test, and a regression analysis using SPSS WIN 18.0. According to the results of the hierarchical regression analysis, the key variables influencing the psychological well-being of middle-aged women included the flow degree in terms of social activity participation and the education level. These variables explained 30% of the psychological well-being of middle-aged women. The higher the education level and the flow degree, the stronger the psychological well-being was. Social activity participation and the flow degree had greater effects on psychological well-being than sociodemographic characteristics. In particular, an increase in the flow of social activities increased psychological well-being. This suggests a need to improve the psychological well-being of middle-aged women by providing them with an environment where they can play social roles. One way to accomplish this is by linking retraining and life-long education-related activities to employment or volunteer activities. This study demonstrates the importance of the flow degree for the psychological well-being of middle-aged women. The results have important policy and theoretical implications.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1713-1716
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• 2016

Background: Liver fluke infection is associated with cholangiocarcinoma; the bile duct cancer found frequently in the northeast and north of Thailand. Prevention and control particularly requires health education and behavior change. Objective: This study aimed to improve health behavior among village health volunteers (VHV) regarding liver fluke exposure in an epidemic area. Materials and Methods: A quasi-experimental study was performed during July 2015 to January 2016 in Sang Kha district of Surin province, Thailand. A total of 67 VHVs underwent a health education program (HEP) and data were collected on knowledge, attitude, and practice (KAP) before and after participation for HEP 3 months with a pre-designed questionnaire. The Students paired T-test was used for comparisons of mean KAP levels before/after the intervention. Results: The results revealed that knowledge (P-value=0.004), attitude (P-value=0.004), and practice level (P-value=0.000) were significantly improved after participation in the HBP. Attitude was significantly associated with knowledge (r=0.266, p<0.05), and practice (r=0.348, p<0.01). Conclusions: The implementation of health education among VHVs is feasible and increases their KAP. This improvement should have potential in liver fluke prevention and control in local communities in rural Thailand.

• International Journal of Automotive Technology
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• 제5권1호
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• pp.33-46
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• 2004

A finite element model development of a 50th percentile male cervical spine is presented in this paper. The model consists of rigid, geometrically accurate vertebrae held together with deformable intervertibral disks, facet joints, and ligaments modeled as a series of nonlinear springs. These deformable structures were rigorously tuned, through failure, to mimic existing experimental data; first as functional unit characterizations at three cervical levels and then as a fully assembled c-spine using the experimental data from Duke University and other data in the NHTSA database. After obtaining satisfactory validation of the performance of the assembled ligamentous cervical spine against available experimental data, 22 cervical muscle pairs, representing the majority of the neck's musculature, were added to the model. Hill's muscle model was utilized to generate muscle forces within the assembled cervical model. The muscle activation level was assumed to be the same for all modeled muscles and the degree of activation was set to correctly predict available human volunteer experimental data from NBDL. The validated model is intended for use as a post processor of dummy measurement within the simulated injury monitor (SIMon) concept being developed by NHTSA where measured kinematics and kinetic data obtained from a dummy during a crash test will serve as the boundary conditions to "drive" the finite element model of the neck. The post-processor will then interrogate the model to determine whether any ligament have exceeded its known failure limit. The model will allow a direct assessment of potential injury, its degree and location thus eliminating the need for global correlates such as Nij.

• Journal of the Optical Society of Korea
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• 제18권5호
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• pp.546-550
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• 2014

To investigate the minimum near-infrared ray intensity required (quantifiable threshold value) for consistent measurements of axial length (AL) using partial coherence interferometry (PCI), we attached two polarizing lenses (PL) to two types of PCI (IOLmaster, ALscan). The near-infrared ray intensity of PCI was modified by rotating the axis of one PL at intervals of 5 degrees. The right eye of each volunteer was measured three times and the AL and signal-to-noise ratio (SNR) was recorded five times for each measurement. Reduction of light intensity was theoretically estimated using Malus' Law. AL was measured consistently with both IOLmaster and ALscan until they reached 55 degrees (1.33 % of intensity) and 60 degrees (0.77%), respectively (P = 0.343, Log-rank test). In contrast, SNR decreased as light intensity decreased. In addition, to analyze media opacities that precluded measurement of AL, we retrospectively reviewed the medical records of patients unmeasurable by PCI (ALscan) from May to November 2013. Thirty-eight of 473 eyes (8.0%) could not be measured using ALscan due to media opacities, such as severe posterior subcapsular cataract (PSC, 11 eyes), hypermature cataract (9 eyes), and vitreous hemorrhage (18 eyes). The mean grades of vitreous haze and PSC were $7.72{\pm}0.96$ and $4.45{\pm}1.04$, respectively. In conclusion, up to 0.77-1.33% of near-infrared rays decreased, and AL could be measured consistently.

• 대한약리학회지
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• 제11권2호
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• pp.55-59
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• 1975

Safety study of the continuous releasing dichlorvos-resin insecticide $(Mopari^{\circledR})$ was conducted in human volunteers and domestic fowls. For the purpose, the potential hazards in using the insecticide were observed in terms of the inhibition of plasma cholinesterase activity and the changes in the liver function (GOT, GPT, Alkaline phosphatase, Bilirubin, Thymol turbidity), the blood picture (RBC, WBC with differential count, Hemoglobin, Hematocrit and ESR) and the urine picture (sugar, albumin, pH and microscopic findings) in 40 healthy adult volunteers and 60 leghorn domestic fowls. In case of the human study the observation was continued for 2 months during the application of the insectiside ($1{\sim}3$ solid formulations/$30m^3$) in the living rooms of ordinary Korean dwelling houses or in the office. In the animal test, however, 1 to 5 solid formulations of the insecticide were applied in the fowl cage of $9.2m^3$ for 5 weeks. Any significant inhibition of the plasma cholinesterase activity was not observed in both the human volunteer and the fowl throughout the experimental period. And the liver function as well as the blood and urine pictures were also not changed after exposure to the vaporizing insecticide. It is considered from the result that the amount of dichlorvos released into the air by the continuous vaporizing dichlorvos-resin insecticide presents no significant hazardous effect on humans or animals in the present experimental condition.