• The Transactions of the Korean Institute of Power Electronics
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• v.27 no.1
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• pp.26-32
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• 2022

This paper proposes a power system that includes a 120k W fuel cell DC-DC converter (FDC) and 30 kW bidirectional DC-DC converter (BHDC) for a 150 kW fuel-cell vehicle. With a high DC link voltage of 800 V, the efficiency and power density of the power electronic components are improved. Through the modular design of FDC and BHDC, electric components are shared, resulting in reduced mass production costs. The switching frequency of 30 kHz of full SiC devices and optimal design of coupled inductor reduce the volume, achieving a power density of 8.3 kW/L. Furthermore, a synergetic operation strategy using variable limiter control of FDC and BHDC was proposed to efficiently operate the fuel cell vehicle considering the fuel cell stack efficiency according to the load. Finally, the performance of the prototype was verified by Highway Fuel Economy Driving Schedule testing, EMI test, and the linked operation between FDC and BHDC. The full load efficiencies of the FDC and BHDC prototypes are 98.47% and 98.74%, respectively.

• Fisheries and Aquatic Sciences
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• v.1 no.1
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• pp.48-62
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• 1998

Seasonal volume transport on the Texas-Louisiana continental shelf is investigated in terms of objectively fitted transport streamfunction fields based on the current meter data of the Texas­Louisiana Shelf Circulation and Transport Processes Study. Adopted here for the objective mapping is a method employing a two-dimensional truncated Fourier representation of the streamfunction over a domain, with the amplitudes determined by least square fit of the observation. The fitting was done with depth-averaged flow rather than depth-integrated flow to reduce the root-mean-square error. The fitting process filters out $11\%$ of the kinetic energy in the monthly mean transport fields. The shelf-wide pattern of streamfunction fields is similar to that of near-surface velocity fields over the region. The nearshore transport, about 0.1 to 0.3 Sv $(1 Sv= 10^6\;m^3/sec)$, is well correlated with the seasonal signal of along-shelf wind stress. The spring transport is weak compared to other seasons in the inner shelf region. The transport along the shelf break is large and variable. In the southwestern shelf break, transport amounts up to 4.7 Sv, which is associated with the activities of the encroaching of energetic anticyclonic eddies originated in Loop Current of the eastern Gulf of Mexico. The first empirical orthogonal function (EOF) of streamfunction variability contains $67.3\%$ of the variance and shows a simple, shelf-wide, along-shelf pattern of transport. The amplitude evolution of the first EOF is highly correlated (correlation coefficient: 0.88) with the evolution of the along-shelf wind stress. This provides strong evidence that the large portion of seasonal variation of the shelf transport is wind-forced. The second EOF contains $23.7\%$ of the variance and shows eddy activities at the southwestern shelf break. The correlation coefficient between the amplitudes of the second EOF and wind stress is 0.42. We assume that this mode is coupled a periodic inner shelf process with a non-periodic eddy process on the shelf break. The third EOF (accounting for $7.2\% of the variance) shows several cell structures near the shelf break associated with the variability of the Loop Current Eddies. The amplitude time series of the third EOF show little correlation with the along-shelf wind.

• Analytical Science and Technology
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• v.27 no.2
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• pp.79-91
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• 2014

Solubility data of carbon dioxide ($CO_2$) in 1-butyl-3-methylpiperidinium bis(trifluoromethylsulfonyl)imide ($[bmpip][Tf_2N]$) ionic liquid are presented at pressures up to about 30 MPa and at temperatures between 303 K and 343 K. As far as we know, the data on the $CO_2$ solubility in the $[bmpip][Tf_2N]$ ionic liquid have never been reported in the literature by other investigators. The solubilities of $CO_2$ were determined by measuring the bubble point or cloud point pressures of the $CO_2+[bmpip][Tf_2N]$ mixtures with various compositions using a high-pressure equilibrium apparatus equipped with a variable-volume view cell. To observe the effect of the cation composing the ionic liquid on the $CO_2$ solubility, the $CO_2$ solubilities in $[bmpip][Tf_2N]$ used in this study were compared with those in 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)-imide ($[bmim]Tf_2N]$). As the equilibrium pressure increased, the $CO_2$ solubility in $[bmpip][Tf_2N]$ increased sharply. On the other hand, the $CO_2$ solubility decreased with increasing temperature. The mole fraction-based $CO_2$ solubilities were almost the same for both $[bmpip][Tf_2N]$ and $[bmim][Tf_2N]$, regardless of temperature and pressure. The phase equilibrium data for the $CO_2+[bmpip][Tf_2N]$ systems have been correlated using the Peng-Robinson equation of state.

• Korean Chemical Engineering Research
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• v.50 no.1
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• pp.35-40
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• 2012

In this study, 1-(2-methoxyethyl)-3-methylimidazolium methanesulfonate ionic liquid has been synthesized, characterized and tested with respect to carbon dioxide absorption with the aim to use it as advanced absorbent materials in fossil fuel processing. The ionic liquid was synthesized by a one step method, low cost. The thermal and chemical stability of selected ionic liquid has been investigated by DSC, TGA and the structure was verified by $^1H$-NMR spectroscopy. The solubility of carbon dioxide in the methanesulfonate-based ionic liquids were measured using a high-pressure equilibrium apparatus equipped with a variable-volume view cell at 30, 50 and $70^{\circ}C$ and pressure up to 195 bar. The results show that carbon dioxide solubilities of 1-(2-methoxyethyl)-3-methylimidazolium methanesulfonate increased with pressure increasing and temperature decreasing, and the carbon dioxide absorption capacity showed 27.6 $CO_2/IL$(g/kg) at $30^{\circ}C$, 13 bar.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.28 no.2
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• pp.95-110
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• 2006

The treatment for oral and maxillofacial carcinoma with chemotherapeutic agents is evaluated by many effective methods to reduce the tumor mass and cancer cell proliferation. However these chemotherapy have many serious side effects, such as bone marrow suppression, renal toxicity, G-I troubles. Therefore a possible approach to develop a clinically applicable chemotherapeutic agent is to screen anticancer activity of Taxol which is known to have very little side effect and have been used to breast cancer and ovarian carcinoma. Taxol is a new anti-microtubular anti-cancer agent extracted from the bark of the Pacific yew, Taxus brevifolia. Paclitaxel(Taxol) acts by promoting tubulin polymerization and over stabilizing microtubules agianst depolymerization. Despite the constant improvements of methods of the cancer treatment especially chemotherapy, the rate of cancer metastasis and recurrent are not decreased. Thus the investigation of new drug which have very little side effect and a possible clinically application continues to be a high priority. Considering that the Taxol have shown very effective chemotherapeutic agent with relatively low toxicity in many solid tumors, it deserves to evaluate its efficacy in oral squamous cell carcinoma. In this study, to investigate the in-vivo and in-vitro anti-cancer efficacy of Taxol in oral squamous cell carcinoma and lastly, the potency of Paclitaxel in the clinical application for oral cancer was evaluated. In vivo study, after HN22 cell line were xenografted in nude mice, the growth of tumor mass was observed, 3 mg/Kg taxol was injected intraperitoneally into nude mice containing tumor mass. The methods of these study were measurement of total volume of tumor mass, histopathologic study, immunohistochemical study, drug resistance assay, growth curve, MTT assay, flow cytometry, cDNA microarray in vivo and in vitro. The results were obtained as following. 1. The visual inspection of the experimental group showed that the volume of the tumor mass was slightly decreased but no significant difference with control group. 2. Ki-67 index was decreased at weeks 4 in experimental group. 3. Microscopic view of the xenografted tumor mass showed well differentiated squamous cell carcinoma and after Taxol injection, some necrotic tissue was seen weeks 4. 4. The growth curve of the tumor cells were decreased after 1day Taxol treatment. 5. According to the MTT assay, HN22 cell line showed relative drug resistancy above $5\;{\mu}g/ml$ concentrations of Taxol. 6. In drug resistance assay, the decrease of cell counts was seen relatively according to concentration. 7. In Flow cytometry, G2M phase cell arrests were seen in low concentration of the Taxol, while S phase cell arrests were seen in high concentration of the Taxol. 8. Using cDNA microarray technique, variable gene expression of ANGPTL4, TXNRD1, FAS, RRAGA, CTGF, CYCLINEA, P19, DUSP5, CEBPG, BTG1 were detacted in the oral squamous cell carcinoma cell after taxol treatment. In this study paclitaxel is effective against oral squamous cell carcinoma cell lines in vitro, but week effect was observed in vivo. So we need continuous study about anticancer effect of taxol in vivo in oral squamous cell carcinoma.

• Journal of Biomedical Engineering Research
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• v.38 no.6
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• pp.313-320
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• 2017

Myocardial infarction is a disease caused by stenosis of the coronary arteries. The high risk of sudden cardiac death due to myocardial infarction has triggered related researches that have been actively studied so far. However, these studies focused on the clinical results, which are mainly based on observations of symptoms due to infarction through electrocardiograms. Therefore, in this study, we tried to analyze the behavior of heart according to the position and volume of infarction lesion through the computer simulation study using three dimensional ventricular models. In order to implement infarction, commercial software was used to simulate cell necrosis due to blockage of a specific coronary. In addition, the conduction block due to infarction was mimicked by reducing the electrical conduction in the infarcted area, which was 100 times less than the electrical conduction of the whole ventricular lattice implemented by the finite element analysis method. Thus, this study classified the infarcted cases into the upper, middle, lower, and apex according to lattice data of eight different infraction areas. In other words, we assumed that myocardial infarction would have inherent electro-dynamic characteristics depending on the location and extent, and analyzed the ventricular electromechanical responses for infarction lesions using a three dimensional cardiac physiome model. The results showed that the volume of infarction did not directly affect the cardiac responses, but the location of the infarction lesions could influence the ventricular pumping efficiency. These suggest that the occlusion of specific coronary arteries may have a fatal effect on the decline in ventricular performance. In conclusion, although location of myocardial infarction lesions is considered to be an important variable to be considered clinically rather than lesion size, quantitative predictions should be made more in the future considering physiological factors such as lesion location and direction of myocardial fiber at that location.

• Biomedical Science Letters
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• v.1 no.1
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• pp.73-79
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• 1995

The effect of prior cumulative mixing was evaluated by means of a simple regression model which used as a dependent variable percentage(%) change of each repeated observed value for the initial value. The red blood cell count (RBC), hematocrit (Hct), and mean corpuscular volume(MCV) showed a significant decrease (p<.01), but % of basophils had a significant increase (p<.05). The ratios of rate of change (regression coefficient/SD) were .0012 for RBC, .0020 for Hct, .0024 for MCV, and .0011 for % of basophils. Of the 19 parameters evaluated, 21% changed.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.24 no.2
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• pp.147-151
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• 2011

We were analyzed the piezoelectric characteristic for electronics printing to inkjet printing system. These applications were possible use to Actuator, MEMS, FPCB, RFID, Solar cell and LCD color filter etc. Piezoelectric print head is firing from ink droplet control consideration ink viscosity properties. At this time, micro pattern for PCB metal printing was possible by droplet control of piezoelectric driving. These driving characteristics are variable voltage pulse waveform. We are used the piezoelectric analysis software of Finite Element Method (FEM), Piezoelectric design parameters are acquired from piezoelectric analysis, and measurement of piezoelectric. It designed for piezoelectric head to possible electric print pattern of inkjet printing system. For this validity we were established through in comparison with simulation and measurement. Designed piezoelectric specification obtained voltage 98V, firing frequency 10 kHz, resolution 360dpi, drop volume 20pl, nozzle number 256, and nozzle pitch 0.33 mm.

• Journal of Microbiology and Biotechnology
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• v.19 no.12
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• pp.1665-1671
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• 2009

Anaerobic digestion sludge was cultivated in an electrochemical bioreactor (ECB) to enrich the hydrogenotrophic methanogens. A modified graphite felt cathode with neutral red (NR-cathode) was charged with electrochemical reducing power generated from a solar cell. The methane and carbon dioxide collected in a Teflon bag from the ECB were more than 80 ml/l of reactant/day and less than 20 ml/l of reactant/day, respectively, whereas the methane and carbon dioxide collected from a conventional bioreactor (CB) was around 40 ml/l of reactant/day, respectively. Moreover, the maximal volume ratios of methane to carbon dioxide (M/C ratio) collected in the Teflon bag from the ECB and CB were 7 and 1, respectively. The most predominant methanogens isolated from the CB on the $20^{th}$, $80^{th}$, and $150^{th}$ days of incubation were hydrogenotrophs. The methanogenic diversity analyzed by temperature gradient gel electrophoresis (TGGE) of the 16S rDNA variable region was higher in the ECB than in the CB. The DNA extracted from the TGGE bands was more than 95% homologous with hydrogenotrophic methanogens in the ECB, but was an aceticlastic methanogen in the CB. In conclusion, the ECB was demonstrated as a useful system for enriching hydrogenotrophic methanogens and increasing the M/C ratio of the gas product.

• Journal of Korea Society of Digital Industry and Information Management
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• v.15 no.4
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• pp.9-17
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• 2019

Sun power generation systems which use large capacity centralized inverters have loss of power generation due to cloud and building shadows, pollution, cell deterioration, etc. To minimize loss of power generation, decentralized solar power systems using multiple micro-inverters are being proposed as an alternative. A distributed solar power system consisting of a system-connected system uses power line communication to collect data from the micro-inverters. Power line communication has the advantage of using power lines without separate lines for data transmission, but in distributed solar power generation systems that use a large number of micro-inverters, the bit error rate is less reliable due to the phenomenon caused by limited transmission power, high load interference and noise, variable signal attenuation, and impedance characteristics. So we proposed wireless intelligent controller for micro-inverter that is used to build distributed solar power systems. and we design and implement that. Further, the proposed wireless intelligent controller for micro-inverter was used to establish a small-volume solar power plant to check its function and operation.