• Journal of Advanced Navigation Technology
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• v.21 no.1
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• pp.50-57
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• 2017

Recently, safety-critical aviation system development programs promoted domestically have been terminated in the middle stage or they have not been put to practical use at the final stage. The program failure may be caused by various factors, but this study focused on imperfect test and evaluation(T&E) procedures. In general, T&E process of a safety-critical system must be distributed throughout the entire life-cycle of the system, have a continuity in phases, and can be implemented in a variety of ways depending on the maturity of the system development and acquisition strategy. This paper aims to present a new strategy by analyzing the domestic and overseas T&E processes to reduce the risk of domestic safety-critical CNS/ATM system development program and increase the success rate of program. First, we discuss the verification and validation techniques for safety-critical systems, analyze the T&E procedures of advanced institutes and the domestic situation, and then compare the domestic and overseas T&E processes to complement the imperfect testing procedure.

• YAKHAK HOEJI
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• v.52 no.1
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• pp.7-11
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• 2008

A high performance liquid chromatographic (HPLC) method for the determination of glycyrrhizic acid was developed for the quality control of traditional herbal medicinal preparation Bu-Zhong-Yi-Qi-Tang (BZYQT), which is well-known herbal medicine used as tonic. RP-HPLC analysis was carried out using Capcell pak $C_{18}$ MG column $(5\;{\mu},\;150{\times}4.6\;mm)$ and a mobile phase consisting of acetonitrile and water containing 0.03% phosphoric acid (pH 2.46) at a flow rate of 1.0 ml/min. The optimum wavelength for the detection of the glycyrrhizic acid was found at 250 nm using diode-array UV/VIS detector. The glycyrrhizic acid in BZYQT shows good linearity $(r^2>0.999)$ in the range of $15\;{\mu}g/ml$ to 500 ${\mu}g/ml$. The limit of detection (LOD) was less than 5 ng and R.S.D for intra-day and inter-day reproducibility was less than 7%. The mean recovery of the glycyrrhizic acid was $97.3{\sim}113.0%$. These results suggest that the developed HPLC method is simple and efficient, and could be contributed for the quality control of commercial BZYQT products.

• Information Systems Review
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• v.7 no.1
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• pp.81-96
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• 2005

Because the web sites are in common today, the access to the web for disabled people and old aging people, what we call accessibility, becomes more important. Even though efforts to reduce the informational gap resulted from the lack of the accessibility have been carried out, the studies in this field in Korea are not still in popular. In this study, previous research on the measurements for the accessibility is reviewed and then a new model measuring accessibility is suggested. To increase the validity of the measurement, both an automated tool and a manual test are employed. First we used the 'A-Prompt', one of the popular automated validation tools and analyzed web sources, and applied manual tests by HPR Screen Reader. With the error rates calculated, the accessibility of the government web sites between Korea and the United States was compared and finally the conclusions were drawn.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1149-1155
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• 2016

Background: Examination of sentinel lymph node (SLN) biopsies provides accurate nodal staging for breast cancer and plays a key role in patient management. Procurement of SLNs and the methods used to process specimens are equally important. Increasing the level of detail in histopathological examination of SLNs increases detection of metastatic tumours but will also increase the burden of busy laboratories and thus may not be carried out routinely. Recommendation of a reasonable standard in SLN examination is required to ensure high sensitivity of results while maintaining a manageable practice workload. Materials and Methods: Twenty-four patients with clinically node-negative breast cancer were recruited. Combined radiotracer and blue dye methods were used for identification of SLNs. The nodes were thinly sliced and embedded. Serial sectioning and immunohistochemical (IHC) staining against AE1/AE3 were performed if initial H&E sections of the blocks were negative. Results: SLNs were successfully identified in all patients. Ten cases had nodal metastases with 7 detected in SLNs and 3 detected only in axillary nodes (false negative rate, FNR=30%). Some 5 out of 7 metastatic lesions in the SLNs (71.4%) were detected in initial sections of the thinly sliced tissue. Serial sectioning detected the remaining two cases with either micrometastases or isolated tumour cells (ITC). Conclusions: Thin slicing of tissue to 3-5mm thickness and serial sectioning improved the detection of micro and macro-metastases but the additional burden of serial sectioning gave low yield of micrometastases or ITC and may not be cost effective. IHC validation did not further increase sensitivity of detection. Therefore its use should only be limited to confirmation of suspicious lesions. False negative cases where SLNs were not involved could be due to skipped metastases to non-sentinel nodes or poor technique during procurement, resulting in missed detection of actual SLNs.

• The Korean Journal of Applied Statistics
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• v.23 no.2
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• pp.345-356
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• 2010

In this paper, we introduce the linear regression model taking the parametric spatial association structure into account and employ it to five-year averaged wind speed data measured at 460 meteorological monitoring stations in South Korea. From the prediction map obtained by the model with spatial association parameters, we can see that inland area has smaller wind speed than coastal regions. When comparing the spatial linear regression model with classical one by using one-leave-out cross-validation, the former outperforms the latter in terms of similarity between the observations and the corresponding predictions and coverage rate of 95% prediction intervals.

• Journal of Community Nutrition
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• v.6 no.1
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• pp.35-41
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• 2004

Cardiovascular disease has the highest mortality rate in South Korea. Previous studies have reported that serum cholesterol level relates to intake of dietary fat and cholesterol. Therefore, in this study we developed a semiquantitative food frequency questionnaire (FFQ) for Koreans with a high-risk of hypercholesterolemia and to validate the FFQ. Semiquantitative FFQ, which includes 160 food items, reflects intakes of energy, fat, saturated fatty acid (SFA), monounsaturated fatty acid (MUPA), polyunsaturated fatty acid (PUPA) and cholesterol. We chose food items from the previous study of our research group (Suh 1999) which reported a nutritional status of Korean adults with normocholesterolemia, borderline and hypercholesterolemia. To validate the FFQ, we compared the results of the FFQ with those of a 3-day food record using a paired t-test. In addition, we calculated Pearson's and Spearmen's correlation coefficients. Intakes assessed by the FFQ and a 3-day food record were classified into quartile and the degree of agreement was obtained. Fifty-five participants responded for the validation study by completing both the FFQ and a 3-day food record. Pearson's correlation coefficients between estimated intakes by respective methods for energy, fat, SF A, MUPA, PUPA and cholesterol were 0.32,0.41,0.37,0.41,0.37 and 0.21, respectively. Spearman's correlation coefficients of energy, fat, SF A, MUPA, PUPA, cholesterol were 0.31, 0.44, 0.39, 0.46, 0.46, and 0.37, respectively. Nutrient densities in 1000kcal were compared. Pearson's correlation coefficient of cholesterol density increased and other values were similar with original values. The average degree of agreement was 67％ that intakes of energy, fat, SF A, MUPA, PUPA and cholesterol assessed by the FFQ and 3-day food records were classified within the same and the adjacent quartile. On the average, 8％ were misclassified into the extreme opposite quartile. The average of weighted kappa was 0.46. In conclusion, the FFQ developed in this study is considered to be a reliable tool to assess nutrient intakes for Koreans with a risk of hypercholesterolemia because the FFQ reflects the intakes of energy, fat, SFA, MUFA, PUPA, and cholesterol.

• The Korean Journal of Food And Nutrition
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• v.31 no.3
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• pp.408-415
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• 2018

This study aimed to investigate the changes in the ${\gamma}$-aminobutyric acid (GABA) content of bitter melon (Momordica charantia L.) cultivated from different regions, with different harvest times and at various maturation stages. Methods for observing the changes in GABA content were validated by determining the specificity, linearity, limit of detection (LOD), limit of quantification (LOQ), and precision and accuracy using the HPLC-FLD system. Results showed high linearity in the calibration curve with a coefficient of correlation ($R^2$) of 0.9999. The LOD and LOQ values for GABA were 0.29 and $0.87{\mu}g/mL$, respectively. The relative standard deviations for intra- and inter-day precision of GABA were less than 5%. The recovery rate of GABA was in the range of 98.77% to 100.50%. The average content of GABA was 0.93 mg/g and Cheongju showed highest GABA content of 1.88 mg/g. As the time of harvest increased from May to September, the GABA content decreased from 1.56 to 0.86 mg/g. Also, maturation of the bitter melon fruit was associated with a decreased in GABA content.

• The Journal of Bigdata
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• v.1 no.1
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• pp.61-66
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• 2016

With big data analysis, companies use the customized marketing strategy based on customer's information. However, because of the concerns about privacy issue and identity theft, people start erasing their personal information or changing the privacy settings on social network site. Facebook, the most used social networking site, has the feature called 'Likes' which can be used as a tool to predict user's demographic profiles, such as sex and age range. To make accurate analysis model for the study, 'Likes' data has been processed by using Gaussian RBF and nFactors for dimensionality reduction. With random Forest and 5-fold cross-validation, the result shows that sex has 75% and age has 97.85% accuracy rate. From this study, we expect to provide an useful guideline for companies and marketers who are suffering to collect customers' data.

• Journal of Sasang Constitutional Medicine
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• v.5 no.1
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• pp.87-104
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• 1993

This study was performed to analize the possibility of validation about Questionaire of Sasang constitution Classification which has been made through several stages for the purpose of promoting the objectivity of Sasang constitutional classification. The results of statistical research about the responses data of Sasang Questionaire are as follow: 1. In the case of mutual relation between the items of the QSCC(Questionaire of Sasang Constitution Classification) and 16PF, every item displaced singnificant result.(in male group) 2. In the investigation to classify the score distribution of Sasang items three groups and analize the gap of mean value in each of 16PF, the characters of each Sasang group were turn out as follows: (1) The Taee-Yang group has extrovert and narcissistic inclination. (2) The So-Yang group shows remarkable extrovert inclination. (3) The Tae-Eum group has hidden fear and introvert inclination. (4) The So-Eum group has revealed physical unstability and introvert inclination. 3. The statistical research of female group didn't display any significant result. It will be necessary to analize the respondent shape of female group and introduce new items to coincident with faminine psychology. 4. In the research using 16PF accompany with QSCC in order to classify the Sasang constitution, the accuracy rate of diagnosis showed inspiring elevation. For that reason, it seems to be desirable to introduce some items of 16PF into QSCC. According to above results, although QSCC contains several problems to be solved, its validity was proved, and the analysis of statistics suggests the possibility to step forward by introducing 16PF in some problems of promoting the accuracy of Sasang Constitutional diagnosis, assuring the objectibity of Sasang constitution classification and so on.

• Fire Science and Engineering
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• v.28 no.5
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• pp.23-29
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• 2014

The present study has been conducted to investigate the validity of the computational fire model and the results predicted by BRANZFIRE zone model and FDS field model are compared with a real scale fire test with spray fire in a multi-compartment. The liquid spray fires fueled with toluene and methanol are used as the fire source and the quantitative measurement of heat release rate is performed in an isolated ISO-9705 compartment with a standard door opening. The temperature field predicted by FDS model showed good agreement with the measurement in the fire room and the corridor, and BRANZFIRE model also gave acceptable result in spite of its simplicity and roughness. The mean temperature predicted by FDS model corresponds with measurement within maximum discrepancy range of 25% and the overall mean value of FDS model matched well with experimental data less than 10%. This study can contribute to establish the limitation and application scope of computational fire model and provide reference data for applying to reliable fire risk assessment.