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Differential Absorption Analysis of Nonmagnetic Material in the Phantom using Dual CT

  • Kim, Ki-Youl;Lee, Hae-Kag;Cho, Jae-Hwan
    • Journal of Magnetics
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    • v.21 no.2
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    • pp.286-292
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    • 2016
  • This study evaluates the change of computer tomography (CT) number in the case of the metal artifact reduction (MAR) algorithm, using the phantom. The images were obtained from dual CT using a gammex 467 tissue characterization phantom, which is similar to human tissues. The test method was performed by dividing pre and post MAR algorithm and measured CT values of nonmagnetic materials within the phantom. In addition, the changes of CT values for each material were compared and analyzed after measuring CT values up to 140 keV, using the spectral HU curve followed by CT scan. As a result, in the cases of N rod (trabecular bone) and E rod (trabecular bone), the CT numbers decreased as keV increasing but were constant above 90 keV. In the cases of I rod (dense bone) and K rod (dense bone), the CT numbers also decreased as keV increased but were uniform above 90 keV. The CT numbers from 40 keV to 140 keV were consistent in the cases of J rod (liver), D rod (liver), L rod (muscle), and F rod (muscle). For A rod (adipose), G rod (adipose), B rod (breast) and O rod (breast), the CT numbers increased as keV increased but were constant after 90 keV. The CT numbers from 40 keV to 140 keV were consistent in the cases of C rod (lung (exhale)), P rod (lung (exhale)), M rod (lung (inhale)) and H rod (lung (exhale)). Conclusively, because dual CT exhibits no changes in image quality and is able to analyze nonmagnetic materials by measuring the CT values of various materials, it will be used in the future as a useful tool for the diagnosis of lesions.

Surface Micromachined Pressure Sensor with Internal Substrate Vacuum Cavity

  • Je, Chang Han;Choi, Chang Auck;Lee, Sung Q;Yang, Woo Seok
    • ETRI Journal
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    • v.38 no.4
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    • pp.685-694
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    • 2016
  • A surface micromachined piezoresistive pressure sensor with a novel internal substrate vacuum cavity was developed. The proposed internal substrate vacuum cavity is formed by selectively etching the silicon substrate under the sensing diaphragm. For the proposed cavity, a new fabrication process including a cavity side-wall formation, dry isotropic cavity etching, and cavity vacuum sealing was developed that is fully CMOS-compatible, low in cost, and reliable. The sensitivity of the fabricated pressure sensors is 2.80 mV/V/bar and 3.46 mV/V/bar for a rectangular and circular diaphragm, respectively, and the linearity is 0.39% and 0.16% for these two diaphragms. The temperature coefficient of the resistances of the polysilicon piezoresistor is 0.003% to 0.005% per degree of Celsius according to the sensor design. The temperature coefficient of the offset voltage at 1 atm is 0.0019 mV and 0.0051 mV per degree of Celsius for a rectangular and circular diaphragm, respectively. The measurement results demonstrate the feasibility of the proposed pressure sensor as a highly sensitive circuit-integrated pressure sensor.

A Comprehensive Study of SARS-CoV-2: From 2019-nCoV to COVID-19 Outbreak

  • Waris, Abdul;Ali, Muhammad;Khan, Atta Ullah;Ali, Asmat;Baset, Abdul
    • Microbiology and Biotechnology Letters
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    • v.48 no.3
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    • pp.252-266
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    • 2020
  • The coronavirus disease 2019 (COVID-19) is a highly contagious pneumonia that has spread throughout the world. It is caused by a novel, single stranded RNA virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Genetic analysis revealed that, phylogenetically, the SARS-CoV-2 is related to severe acute respiratory syndrome-like viruses seen in bats. Because of this, bats are considered as a possible primary reservoir. The World Health Organization has declared the COVID-19 outbreak as a pandemic. As of May 27, 2020, more than 5,406,282 confirmed cases, and 343,562 confirmed deaths have been reported worldwide. Currently, there are no approved vaccines or antiviral drugs available against COVID-19. Newly developed vaccines are in the first stage of clinical trials, and it may take a few months to a few years for their commercialization. At present, remdesivir and chloroquine are the promising drugs for treating COVID-19 patients. In this review, we summarize the diversity, genetic variations, primary reservoirs, epidemiology, clinical manifestations, pathogenesis, diagnosis, treatment strategies, and future prospects with respect to controlling the spread of COVID-19.

Anti-slamming bulbous bow and tunnel stern applications on a novel Deep-V catamaran for improved performance

  • Atlar, Mehmet;Seo, Kwangcheol;Sampson, Roderick;Danisman, Devrim Bulent
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.5 no.2
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    • pp.302-312
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    • 2013
  • While displacement type Deep-V mono hulls have superior seakeeping behaviour at speed, catamarans typically have modest behaviour in rough seas. It is therefore a logical progression to combine the superior seakeeping performance of a displacement type Deep-V mono-hull with the high-speed benefits of a catamaran to take the advantages of both hull forms. The displacement Deep-V catamaran concept was developed in Newcastle University and Newcastle University's own multi-purpose research vessel, which was launched in 2011, pushed the design envelope still further with the successful adoption of a novel anti-slamming bulbous bow and tunnel stern for improved efficiency. This paper presents the hullform development of this unique vessel to understand the contribution of the novel bow and stern features on the performance of the Deep-V catamaran. The study is also a further validation of the hull resistance by using advanced numerical analysis methods in conjunction with the model test. An assessment of the numerical predictions of the hull resistance is also made against physical model test results and shows a good agreement between them.

Distance and Probability-based Real Time Transmission Scheme for V2V Protocol using Dynamic CW allocation (V2V 프로토콜에서 실시간 전송을 위한 동적 CW 할당 기법)

  • Kim, Soo-Ro;Kim, Dong-Seong;Lee, Ho-Kyun
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.2
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    • pp.80-87
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    • 2013
  • This paper proposes a CW (Contention window) allocation scheme for real-time data transmission of emergency data on VANET (Vehicle to vehicle Ad hoc Network, V2V) protocol. The proposed scheme reduces the probability of packet collisions on V2V protocol and provides bandwidth efficiency with short delay of emergency sporadic data. In the case of high density traffic, the proposed scheme provides a decrease of recollision probability using dynamic CW adjustments. For the performance analysis, a throughput, end-to-end delays, and network loads were investigated on highway traffic. Simulation results show the performance enhancements in terms of the throughput, end-to-end delays, and network loads.

Application of Thermotolerant Yeast at High Temperature in Jar-fermentor Scale.

  • Sohn, Ho-Yong;Kim, Young-Ho;Rhee, In-Koo
    • Journal of Microbiology and Biotechnology
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    • v.4 no.4
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    • pp.316-321
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    • 1994
  • We investigated the possibility of industrial application and economit process of high temperature fermentation by thermotolerant alcohol producing yeasts as previously reported. From the 20% glucose media, the RA-74-2 produced 11.8% (v/v) ethanol at $32^{\circ}C$ (0.5% inoculum) and 10.6% (v/v) ethanol at $40^{\circ}C$ (3% inoculum), respectively. Also, 11.3% (v/v) ethanol was produced for 96 hours in the temperature-gradient fermentation. These results suggest that the RA-74-2 could isuccessfully be applied to save the cooling water and energy in industrial scale without re-investment or modification of established fermentation systems. When potato starch was used as the substrate for the RA-74-2, high temperature fermentation above $40^{\circ}C$ was more appropriate for industrial utilization because organic nitrogen was not necessary to economical fermentation. As the naked barley media just prior to industrial inoculation, taken from the Poongkuk alcohol industry Co., were used, 9.6% (v/v) ethanol was produced at $40^{\circ}C$ for 48 hours in jar-fermentor scale (actually, 9.5-9.8% (v/v) ethanol was produced at 30~$32^{\circ}C$ for 100 hours in industrial scale). The ethanol productivity was increased by the high glucoamylase activity as well as the high metabolic ratio at $40^{\circ}C$ Therefore, if the thermotolerant yeast RA-74-2 would be used in industrial scale, we could obtain a high productivity and saving of the cooling water and energy. Meanwhile, the RA-912 produced 6%(v/v) ethanol in 10% glucose media at $45^{\circ}C$ and showed the less ethanol-tolerance compared with industrial strains. As the produced alcohol was recovered by the vacuum evaporator at $45^{\circ}C$ in 15% glucose media, the final fermentation ratio was enhanced (76% of theoretical yields). This suggest that a hyperproductive process could be achieved by a continuous input of the substrate and continuous recovery of the product under vacuum in high cell-density culture.

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Molecular Characterization of $Ca_v2.3$ in Rat Trigeminal Ganglion Neurons

  • Fang, Zhi;Kim, Joong-Soo;Oh, Seog-Bae
    • International Journal of Oral Biology
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    • v.31 no.2
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    • pp.45-51
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    • 2006
  • R-type($Ca_v2.3$) calcium channel contributes to pain sensation in peripheral sensory neurons. Six isoforms of $Ca_v2.3$ that result from combinations of presence or deletion of three inserts(insert I and insert in the II-III loop, and insert III in N-terminal regions) have been demonstrated to be present in different mammalian tissues. However, the molecular basis of $Ca_v2.3$ in trigeminal ganglion(TG) neurons is not known. In the present study, we determined which isoforms of $Ca_v2.3$ are expressed in rat TG neurons using the RT-PCR analysis. Whole tissue RT-PCR analyses revealed that only two isoforms, $Ca_v2.3a$ and $Ca_v2.3e$, were present in TG neurons. From single-cell RT-PCR, we found that $Ca_v2.3e$ rather than $Ca_v2.3a$ was the major isoform expressed in TG neurons, and $Ca_v2.3e$ was preferentially detected in small-sized neurons that express nociceptive marker, transient receptor potential vanilloid 1(TRPV1). Our results suggest that $Ca_v2.3e$ in trigeminal neurons may be a potential target for the pain treatment.

SNU 1.5 MV Van de Graaff Accelerator (V) -on the Operation of the High Voltage Stabilization System- (NU 1.5MV 반데그라프 가속기 (V) -고전압 안정화 계통의 동작-)

  • Bae, Y.D.;Bak, H.I.;Chung, K.H.;Woo, H.J.;Choi, B.H.
    • Nuclear Engineering and Technology
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    • v.19 no.2
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    • pp.115-121
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    • 1987
  • A high voltage stabilization system for the SNU 1.5MV Tandem Van do Graaff accelerator was set up and its operational characteristics were examined and optimized. The optimum parameters of beam transport system were experimentally determined, and under the proper condition the accelerated proton beam current of 350nA was obtained at the target chamber. Without the high voltage stabilization the observed magnitude of voltage fluctuation was $\Delta$V/ V=5.2$\times$10$^{-3}$ without ion beam and 7.2$\times$10$^{-3}$ with ion beam, respectively, and its apparent ripple frequency for voltage fluctuations was about 3Hz or less. Through the optimized operation of the high voltage stabilization system, the terminal voltage fluctuation was reduced to $\Delta$V/V=2.45$\times$10$^{-4}$ and the energy stability with $\Delta$E/E=2.44$\times$10$^{-4}$ was steadily maintained at the 247.3kV terminal voltage, and the stabilization factor was deduced to be 29.4.

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A NOTE ON WEAKLY IRRESOLUTE MAPPINGS

  • Chae, Gyu-Ihn;Dube, K.K.;Panwar, O.S.
    • East Asian mathematical journal
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    • v.1
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    • pp.89-100
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    • 1985
  • A mapping f: X$\rightarrow$Y is introduced to be weakly irresolute if, for each x $\varepsilon$ X and each semi-neighborhood V of f(x), there exists a semi-neighborhood U of x in X such that $f(U){\subset}scl(V)$. It will be shown that a mapping f: X$\rightarrow$Y is weakly irresolute iff(if and only if) $f^{-1}(V){\subset}sint(f^{_1}(scl(V)))$ for each semiopen subset V of Y. The relationship between mappings described in [3,5, 6,8] and a weakly irresolute mapping. will be investigated and it will be shown that every irresolute retract of a $T_2$-space is semiclosed.

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A NEW LOWER BOUND FOR THE VOLUME PRODUCT OF A CONVEX BODY WITH CONSTANT WIDTH AND POLAR DUAL OF ITS p-CENTROID BODY

  • Chai, Y.D.;Lee, Young-Soo
    • Honam Mathematical Journal
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    • v.34 no.3
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    • pp.403-408
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    • 2012
  • In this paper, we prove that if K is a convex body in $E^n$ and $E_i$ and $E_o$ are inscribed ellipsoid and circumscribed ellipsoid of K respectively with ${\alpha}E_i=E_o$, then $\[({\alpha})^{\frac{n}{p}+1}\]^n{\omega}^2_n{\geq}V(K)V({\Gamma}^{\ast}_pK){\geq}\[(\frac{1}{\alpha})^{\frac{n}{p}+1}\]^n{\omega}^2_n$. Lutwak and Zhang[6] proved that if K is a convex body, ${\omega}^2_n=V(K)V({\Gamma}_pK)$ if and only if K is an ellipsoid. Our inequality provides very elementary proof for their result and this in turn gives a lower bound of the volume product for the sets of constant width.