• Korean Journal of Clinical Pharmacy
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• v.15 no.1
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• pp.41-45
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• 2005

심바스타틴은 cholesterol 생합성 과정에서 속도 조절 효소인 HMG-CoA reductase의 강력한 상경적 길항약으로서 고지혈증 치료에 널리 쓰이는 약물이다. 심바스타틴 제제인 MSD 사의 조코 20 mg정을 대조약으로 하여 시험약인 유영 제약의 엘바스타 20mg정의 생물학적 동등성 평가를 하기 위해 22명의 건강한 지원자를 모집하였다. 지원자를 두 군으로 나누어 2정씩 투여하였고 $2{\times}2$ 교차시험을 실시하였다. 심바스타틴의 혈장 중의 농도를 정량하기 위하여 발리데이션된 LC/MS/MS를 사용하였다. 채혈 시간은 투약 전 및 투약 후 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, 10, 12 시간에 걸쳐 총 12시점에 걸쳐 시행하였다. 생물학적 동등성을 판정하기 위한 파라미터로 12시간까지의 혈장 중 농도곡선 하 면적 ($AUC_{12hr}$)과 최고 혈중 농도($C_{max}$)를 사용하였다. 12시간 까지의 혈중 농도 곡선 하 면적의 기하 평균은 $17.30ng{\cdot}ml/hr$(시험약)과 $17.35ng{\cdot}ml/hr$(대조약)으로 나타났다. 최고 혈중 농도의 경우 각 각 5.08 ng/ml(시험약)과 5.20 ng/ml(대조약)으로 관찰 되었다. $AUC_{12hr}$의 경우 로그변환한 평균치 차의 $90{\%}$ 신뢰구간이 log0.8510 - log1.1694이었고, $C_{max}$의 경우 log0.8176 - log1.1649로 계산되어 두 항목 모두 log0.8-log1.25이어야 한다는 식품의약품 안전청과 FDA의 기준을 모두 만족시켰다. 이상의 결과를 종합하면 시험약 엘바스타 정 20mg은 대조약 조코정 20 mg에 대하여 생물학적 동등한 것으로 판정되었다.트리머 전기비저항 탐사를 수행하였다. 이를 통해 하저에 케이블을 설치하는 방식에 비해 매우 신속하고 경제적으로 하저에 분포하는 이상대의 분포범위와 발달방향을 규명할 수 있었다.대에 대해 가장 효과적이다. 모델과 현장 적용 결과들을 통해 GRM SSM 방법을 이용하여 불규칙한 굴절면을 가진 지층들에 대해 좀 더 신뢰할 수 있는 정밀한 탄성파 속도를 산출할 수 있음을 보여주고 있다.별한 주의를 기울여야 한다.EX>$\alpha/\beta$=10인 경우 $62.0\~121.9\;Gy_{10}$ (중앙값: $93.0\;Gy_{10}$)의 분포를, ${\alpha/\beta}=3$인 경우 $93.6\~187.3\;Gy_3$ (중앙값=$137.6\;Gy_3$ )의 분포를 보였다. MD-BED $Gy_3$는 직장합병증 발생과의 관계는 통계적으로 유의하였고, 방광합병증과는 유의하지 않았다. 직장합병증과의 연관성은 MD-BED $Gy_3$보다 개별 환자의 직장전벽 총 선량 BED값인 R-BED $Gy_3$가 훨씬 더 높았다. 요도카테터 풍선의 후방지점이 대변하는 방광의 총 선량 BED값인 V-BED $Gy_3$도 방광합병증과 경향성 테스트에서 통계적 유의성을 보였다. 하지만, 어떠한 방사선선량도 골반제어율과 의미 있는 상관관계를 보이지 않았다. 본 기관에서 주치의의 선호도에 따라 강내근접치료가 외부방사선치료의 중간에 시행되는 형태인 샌드위치기법과 외부방사선치료 후반부에 시행되는 순차적 기법으로 구분하였을 때, 두 방식간 치료성적 및 합병증의 차이는 없었다. 총 치료기간에 대한 분석에서는 치료기간이 길어질수록 재발 위험이 커지는 경향을 보였으나, 나이 및 병기, 종양의 크기, MD-BED $Gy_{10}$

• Journal of the Korean Society of Clothing and Textiles
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• v.40 no.1
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• pp.97-113
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• 2016

This study develops pant patterns using body shape, measurement and shell mesh data to decide optimal women's pants according to styles with excellent size, fit and shape for different individuals and silhouettes. Standard landmarks, lines, triangles and structures were set on a 3D scanned lower body shell to represent women in their twenties and flattened as a 2D pattern. Patterns were created and analyzed according to culotte, formal, slacks and tight type considering crotch shape, location of the crotch point, and adjusting waist darts. Flattened patterns were rotated to compare existing methods. The crease lines were then set through the hip protrusion point and compared. The main factor of the pant pattern were extracted, total rise, crotch depth, crotch width, angle of center line, shape of the center line curve, the thigh width, the amount of waist dart, and crease line position. With going tight style from the culotte, the fits are closer to the figure with minimized thigh circumference, the dart amount decreases, the crotch depth increases, the crotch extensions were shorter, and the angle of the center back increased. The total rise is U shape for culotte and is closer to V shape as the silhouette tightens. T-test of appearance evaluation of the developed pant pattern were conducted after analyzing measurements and shapes of each styles. The results of the developed patterns were superior to existing patterns in accordance to hip line between body and pants as well as appearance evaluation. We found systematic mechanisms among pattern factors that create various pant silhouettes. Evidence on classification of the silhouettes of traditional types of pants were explained objectively through the process of playing out 3D forms.

• The Research Journal of the Costume Culture
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• v.24 no.5
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• pp.531-543
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• 2016

The purpose of this study is to classify fashion lifestyle types for color planning and to propose color planning of spring & summer by fashion lifestyle by analyzing preferred colors by fashion lifestyle type. The survey was conducted on women between the ages of 30 and 59 using a separately prepared questionnaire and color sample table and also through one-on-one interviews. The results of this study are as follows. First, the participants' fashion lifestyles were divided into three categories: information individuality type, display type, and practicality type. Second, regarding basic colors: the basic color consistently used for a long time, it was found that there were significant differences in preferred hue and tone according to the types of fashion lifestyles. Specifically, the most preferred hue of all the fashion lifestyle types was achromatic color N and the most preferred tone was V. Third, regarding color trends: the trendy color occupying a market transiently, there were significant differences in preferred hue and preferred tone according to the types of fashion lifestyle. The most preferred hue of all the fashion lifestyle types was B. The most preferred tone of the information individuality type and the display type was V, and that of the practicality type was B. The study found that, in color planning, fashion lifestyles can function as an effective tool to subdivide consumers. Based on the empirical results of this study, I propose that color planning should be based on the type of fashion lifestyle.

• Journal of Fashion Business
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• v.21 no.4
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• pp.73-89
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• 2017

This research aimed to identify the characteristics of outdoor apparel market for new seniors. To achieve this goal, influence of new seniors' lifestyle and apparel purchase criteria of design preferences of outdoor apparel products were investigated. An online-survey was conducted targeting fifties who have bought outdoor apparel within one year. The collected data were carried out for factor analysis, independent sample T-test, and regression analysis by using SPSS 22.0. Results showed that new seniors' lifestyles were composed of appearance-orientation, well-being diet, well-being exercise, self-development, and challenge-orientation. Purchase criteria of outdoor apparels were factored out as practical, aesthetic, and social. Appearance -orientation and self-development affect aesthetic and social factors. Well-being diet influences all factors of purchase criteria. Challenge -orientation has effect only on social factor. Women favored round-and V-neckline more than men did as well as preferred half and 3/4 long for sleeve. Customers who value practical purchase criteria preferred half-sleeve, zipper, and button-closure designs. In contrast, customers who have aesthetic purchase criteria like round/V-neckline and cap sleeve. Social factor affected high neckline and vivid-tone color preference significantly. As outdoor design for new senior it is critical to introduce differentiation of outdoor brand with various designs combining functionalities of outdoor activities and style looking young and dandy, which is highlighted as trendy and casual, over current outdoor apparels' unified design.

• Electrical & Electronic Materials
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• v.9 no.5
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• pp.455-462
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• 1996

Automobile Fuel Shortage Detecting Sensor, in this paper, was fabricated by using heat dissipation coefficient difference between gasoline and air condition the NTC thermistor of Mn-Ni Co system with the composition ratio of Mn$_{3}$O$_{4}$ : 9wt%, NiO : 28wt%, and CO$_{3}$O$_{4}$ : 61wt%. The condition of sensor operation is that, for turn-on characteristics, the time of arriving at 135mA must be less than 180 second when the DC voltage of 11V is applied in the air condition of -10.deg. C and that, for turn-off characteristics, the saturation current must be less than 60mA when the DC voltage of 15V is applied in the gasoline condition of 60.deg. C. It is known, from the experimental results, that the resistance range and B-constant for the Automobile Fuel Shortage Detecting Sensor with dimension of 5*3*0.9mm were 850-1150.ohm. and 1150-1250.deg. C, respectively and the resistance range and B-constant were agree with that of sensor operation condition. When Bi$_{2}$O$_{3}$ of 0-0.5wt% was added to Mn$_{3}$O$_{4}$ : 9wt%, NiO : 28wt%, and CO$_{3}$O$_{4}$ : 61wt% composition, the resistivity and B-value were 380-430(.ohm.-cm) and 1930 - 2030, respectively. Particularly, for Bi$_{3}$O$_{3}$ of 0.25-0.5wt%, the sintering density of over 90% and the operation characteristics necessary to Automobile Fuel Shortage Detecting Sensor were obtained. The difference of heat dissipation coefficient gasoline and air condition was 15 times.

• Korean Journal of Human Ecology
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• v.22 no.1
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• pp.201-213
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• 2013

This study was conducted to identify adults' knowledge, attitude, dietary behavior, and lifestyle for cancer prevention, and to examine the relation between these variables. The participants were 414 adults in the Jeonbuk area. The data were analyzed using Pearson correlation coefficients, ANOVA and Duncan test with SPSS v. 12.0. The score for participants' knowledge about cancer was 23.98 points of a possible 30, the score for attitude towards cancer was 44.46 points of a possible 55, the score for preventive dietary behavior for cancer was 36.79 points of a possible 55, and their score for preventive lifestyle for cancer was 29.76 points of a possible 40. The knowledge, attitude towards cancer, dietary behavior, and lifestyle for cancer prevention showed significant differences according to the general characteristics (e.g., age, religion, monthly income, educational level, job, health condition, and interests). There was a significant positive correlation between knowledge about cancer, attitude towards cancer, dietary behavior, and lifestyle for cancer prevention. Dietary behavior for cancer prevention showed a positive correlation with lifestyle for cancer prevention. In conclusion, it is necessary to consider the related factors for the development and implementation of systematic education programs that can encourage and promote preventive health behavior for cancer among adults.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.3
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• pp.418-430
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• 2008

The purpose of this study were 1) to subdivide sportswear consumers according to consuming desire of sports 2) to identify the differences in lifestyle and sportswear benefits sought. The data were collected via a questionnaire from 312 consumer who have been purchased sportswear and living in Seoul. The results of this study were as follows: 1) Sportswear consumers were divided into four segments: sports mania, attractive body pursuers, passive followers, mind purifiers. 2) Six realms of lifestyle such as clothing, food, home & interior, leisure life, consumption and sense of values were factor-analysed separately, and lifestyle factors which showed significant differences among segments are I) fashion ostentation in the realm of clothing ii) western style, health-oriented in the realm of food, iii) sports life enjoyment, sociable life, hoped-for foreign travel in the realm of leisure life, iv) brand oriented, price comparison, sale goods preference in the realm of consumption, and v) realist, interpersonal skills, strong personality, individualism in the realm of values 3) Five factors of sportswear benefits sought which showed significant differences among segments are comfortability/practicality, ideal body/good-looking, individual character, fashion! ostentation, and brand oriented.

• Korean Journal of Human Ecology
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• v.20 no.6
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• pp.1135-1151
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• 2011

This study examined green consumption behavior according to the lifestyles of college students. The data were collected from 314 college students in Yeungnam region by a self-administered questionnaire. Frequencies, Cronbach's alpha, factor analysis, cluster analysis, chi-square tests, one-way analysis of variance, Duncan's multiple range tests, Pearson's correlation analysis, and multiple regression analyses were conducted by SPSS Windows V.18.0. According to the result of factor analysis, lifestyles were categorized into six factors: thrift-saving type, enthusiastic activity type, brand ostentation type, freedom-seeking type, material oriented type, and practice-seeking type. Cluster analysis showed respondents belonged to one of four groups: thrift practice group, indifference group, freedom-seeking group, and material ostentation group. The levels of green purchase behavior, green usage behavior and green disposal behavior of the respondents was not high. The thrift practice group showed higher levels of green purchase behavior, green usage behavior, and green disposal behavior. Finally, according to multiple regression analyses, environmental consciousness, knowledge about green consumption, lifestyle groups were the significant factors affecting green consumption behaviors. These results imply that green consumption education for college students should be activated to induce green life.

• The Research Journal of the Costume Culture
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• v.6 no.4
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• pp.13-25
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• 1998

This study focuses on the visual effects of various neckline-haristyle combinations on the perception of face image and type. The study employed a model with oval face and examined 35 combinations made up of five necklines and seven hairstyles. Looking at various face images depending upon different necklines, in case of round, V, boat square, and high necklines, long wave hair and medium wave hair produced a feminine image of marked individuality; long straight hair that covers the forehead and medium straight hair gave an image of charm and purity as well as an image of neatness; and long straight hair short cut hair showed an intellectual image. Regarding the perceptual type of face depending upon the different necklines of round, V, square, and high, the long straight hair covering the forehead and medium wave hair had the effect of an optical illusion that made the face look short and round; and short cut hair made the face line look distinct and the face look oval and slender.

• KSBB Journal
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• v.28 no.4
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• pp.238-243
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• 2013

Astaxanthin is one of the carotenoid with strong antioxidant. The conditions of extraction of astaxanthin from Portunus trituberculatus were optimized in this work. Six factors of conditions such as, extraction method, extraction solvent, ratio of solvent to raw material, temperature, and time, were investigated. For the increase of the extraction yield, ionic liquids were used as additives in the extraction solvent. The optimum extraction conditions were found: heat reflux extraction, Dichloromethane/methanol (25:75, v/v) as solvent, 1:30 of the ratio of solvent raw material, $80^{\circ}C$, 90 min, and ionic liquid as additive. As a result, 45.81 ${\mu}g/g$ of astaxanthin was extracted from waste.