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The Impact of Obesity Surgery on Serum Uric Acid in People With Severe Obesity: A Retrospective Study

  • Leila Vafa;Masoud Amini;Hooman Kamran;Ladan Aghakhani;Seyed Vahid Hosseini;Zahra Mohammadi;Neda Haghighat
    • Clinical Nutrition Research
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    • v.12 no.1
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    • pp.21-28
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    • 2023
  • Studies indicate an association between hyperuricemia (HUA) and metabolic syndrome risk factors. On the other hand, obesity is a major modifiable and independent risk factor for HUA and gout. However, evidence concerning the effects of bariatric surgery on serum uric acid levels is limited and not completely clarified. This retrospective study was carried out with 41 patients who underwent sleeve gastrectomy (n = 26) and Roux-en-Y gastric bypass (n = 15) from September 2019 to October 2021. Anthropometric, clinical, and biochemical data, including uric acid blood urea nitrogen and creatinine fasting blood sugar (FBS), serum triglyceride (TG), and serum cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), were measured preoperatively and postoperative 3, 6 and 12 months. From baseline to 6 and 12 months, bariatric surgery resulted in a significant decrease in serum uric acid of patients with severe obesity (p < 0.001). The decreases in serum FBS, TG, and cholesterol of patients were significant during 6 and 12 months of follow-up (p < 0.05). However, the HDL increase of patients was not statistically significant in 6 and 12 months (p > 0.05). Besides, although patients' serum level of LDL decreased significantly during the 6 months of follow-up (p = 0.007), it was not significant after 12 months (p = 0.092). Bariatric surgery significantly reduces serum uric acid levels. Therefore, it may be an effective supplementary therapy for lowering serum uric acid concentrations in morbidly obese patients.

WETTING PROPERTIES AND INTERFACIAL REACTIONS OF INDIUM SOLDER

  • Kim, Dae-Gon;Lee, Chang-Youl;Hong, Tae-Whan;Jung, Seung-Boo
    • Proceedings of the KWS Conference
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    • 2002.10a
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    • pp.475-480
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    • 2002
  • The reliability of the solder joint is affected by type and extent of the interfacial reaction between solder and substrates. Therefore, understanding of intermetallic compounds produced by soldering in electronic packaging is essential. In-based alloys have been favored bonding devices that demand low soldering temperatures. For photonic and fiber optics packaging, m-based solders have become increasingly attractive as a soldering material candidate due to its ductility. In the present work, the interfacial reactions between indium solder and bare Cu Substrate are investigated. For the identification of intermetallic compounds, both Scanning Electron Microscopy(SEM) and X-Ray Diffraction(XRD) were employed. Experimental results showed that the intermetallic compounds, such as Cu$_{11}$In$_{9}$ was observed for bare Cu substrate. Additionally, the growth rate of these intermetallic compounds was increased with the reaction temperature and time. We found that the growth of the intermetallic compound follows the parabolic law, which indicates that the growth is diffusion-controlled.d.

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High-yield Expression and Characterization of Syndecan-4 Extracellular, Transmembrane and Cytoplasmic Domains

  • Choi, Sung-Sub;Kim, Ji-Sun;Song, Jooyoung;Kim, Yongae
    • Bulletin of the Korean Chemical Society
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    • v.34 no.4
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    • pp.1120-1126
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    • 2013
  • The syndecan family consists of four transmembrane heparan sulfate proteoglycans present in most cell types and each syndecan shares a common structure containing a heparan sulfate modified extracellular domain, a single transmembrane domain and a C-terminal cytoplasmic domain. To get a better understanding of the mechanism and function of syndecan-4 which is one of the syndecan family, it is crucial to investigate its three-dimensional structure. Unfortunately, it is difficult to prepare the peptide because it is membrane-bound protein that transverses the lipid bilayer of the cell membrane. Here, we optimize the expression, purification, and characterization of transmembrane, cytoplasmic and short extracellular domains of syndecan4 (syndecan-4 eTC). Syndecan-4 eTC was successfully obtained with high purity and yield from the M9 medium. The structural information of syndecan-4 eTC was investigated by MALDI-TOF mass (MS) spectrometry, circular dichroism (CD) spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy. It was confirmed that syndecan-4 eTC had an ${\alpha}$-helical multimeric structure like transmembrane domain of syndecan-4 (syndecan-4 TM) in membrane environments.

Transflective liquid crystal display with single cell gap and simple structure

  • Kim, Mi-Young;Lim, Young-Jin;Jeong, Eun;Chin, Mi-Hyung;Kim, Jin-Ho;Srivastava, Anoop Kumar;Lee, Seung-Hee
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.340-343
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    • 2008
  • This work reports the simple fabrication of the single cell gap transflective liquid crystal display (LCD) using wire grid polarizer. The nano sized wire grid polarizer was patterned on common electrode itself, on the reflective part of FFS (Fringe field switching) mode whereas the common electrode was unpatterned at transmissive part. However, this structure didn't show single gamma curve, so we further improved the device by patterning the common electrode at transmissive part. As a result, V-T curve of proposed structure shows single gamma curve. Such a device structure is free from in-cell retarder, compensation film and reflector and furthermore it is very thin and easy to fabricate.

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Measurement of the excited Xe atoms density of matastable state$(1S_5)$ under various binary gas mixtures(Ne-Xe) by Laser Absorption Spectroscopy.

  • Lee, Jun-Ho;OH, P.Y.;Moon, M.W.;Ko, B.D.;Jeong, J.M.;Lee, H.J.;Choi, E.H.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07b
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    • pp.1218-1220
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    • 2005
  • We have developed laser absorption spectroscopy system for the measurement of excited Xe atoms in micro-discharged AC-PDP plasma. In this study, we have measured the absorption signals for the $1S_5$ xenon metastable state in the PDP cell with the various gas mixtures of Ne-Xe(1%), Ne-Xe(4%) and Ne-Xe(10%) under fixed gas pressure of 350 Torr and the eletrode gap distance of 50um. It is found that the maximum excited xenon densities are $1.2^{\ast}10^{12}\;cm^{-3}$, $1.8^{\ast}10^{12}\;cm^{-3}$ and $2.7^{\ast}10^{12}cm^{-3}$ for gas mixtures of Ne-Xe(1%), Ne-Xe(4%) and Ne-Xe(10%) respectively, in this experiment.

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Studies on Fabrication of Novel Micromachined SIR BPF using DAML (DAML 구조를 이용한 새로운 구조의 SIR BPF 의 설계 및 제작)

  • Baek, Tae-Jong;Kim, Sung-Chan;Lim, Byeong-Ok;Shin, Dong-Hoon;Rhee, Jin-Koo
    • Proceedings of the IEEK Conference
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    • 2005.11a
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    • pp.623-626
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    • 2005
  • In this paper, we proposed a new type SIR bandpass filter using DAML. This filter is consisted of 2 layers with MEMS resonator layer and CPW feed line. DAML ring resonator is elevated with $10\;{\mu}m$ height from GaAs substrate. Using MEMS processing, we are able to realize SIR bandpass filter easily. Furthermore it is useful to integrate on conventional MMICs because it has CPW interfaces and ring resonator is isolated from substrate by air-gap. We optimized and measured the results that $S_{21}$ attenuation at rejected band is over 15 dB, insertion loss is inside the limit of 3 dB, and relative bandwidth is about 10 % at 60 GHz

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High performance couplers using micromachined transmission lines in millimeter-wave band (마이크로 머시닝 기술을 이용한 밀리미터파 대역 저 손실 결합기에 관한 연구)

  • Lim, Byeong-Ok;Kim, Sung-Chan;Baek, Tae-Jong;Shin, Dong-Hoon;Rhee, Jin-Koo
    • Proceedings of the IEEK Conference
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    • 2005.11a
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    • pp.925-928
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    • 2005
  • In this study, we fabricated the DAMLs using surface micromachining technology as well a low loss coupler for the millimeter-wave band applications using these DAMLs. The structure of DAML is that a signal line is supported on ground plane by dielectric posts. Therefore it has advantages about the loss characteristic and the stable structure. The other advantage of the DAML process is a simple and convenient technique using 4 mask steps, even if it has a micromachining technology. The lowest loss of the fabricated DAML was obtained 2.2 dB/cm at 110 GHz. To obtain the low loss characteristic, couplers were designed and fabricated by using DAMLs. The fabricated ring hybrid coupler has the coupling of 3.58 dB and the thru of 3.31 dB at 60 GHz. We can also obtain the coupling of 3.42 dB, the thru of 3.82 dB from fabricated branch line coupler at 60 GHz.

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Influence of reset pulse form on electrical characteristics in AC-PDP

  • Cho, T.S.;Ko, J.J.;Lee, C.W.;Cho, G.S.;Choi, E.H.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2000.04a
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    • pp.159-161
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    • 2000
  • After the square type reset pulse, the condition of remaining wall charge has been experimentally investigated in AC-PDP with VDS (Versatile Driving Simulator) system, in which arbitrary driving waveform and sequence can be used. After the self-discharge process, almost wall charges are eliminated. But some wall charges are not and its quantity is dependent on the voltage of the reset pulse. When the voltage of the reset pulse is growing, its quantity is decreased. But if the voltage of the reset pulse is above 300V, the wall voltage due to remaining wall charge is constant and its value is found out 6V. Also it is found that its polarity is always same with the one made by the reset pulse. It means that the polarity is not changed by the self-discharge.

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Study on Planar Orientation and Selective Reflection of Cholesteric Liquid Crystals (콜레스테릭 액정의 Planar 배열과 선택 반사 특성에 관한 연구)

  • Jung, Gap-Ha;Seo, In-Seon;Lee, Mong-Ryong;Choi, Suk-Won;Song, Ki-Gook
    • Polymer(Korea)
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    • v.34 no.3
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    • pp.242-246
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    • 2010
  • FTIR spectroscopy has been employed in order to quantitatively investigate the relationship between planar arrangements and selective reflectance of cholesteric liquid crystals. It was found that the selective reflection was enhanced as the amount of planar arrangements in cholesteric liquid crystals increased. Although the planar arrangements of cholesteric liquid crystals can be induced only by the shear force effect, it was more effective to use the alignment layer to obtain the perfect planar arrangements.

Austenite Stability of Sintered Fe-based Alloy (철계 소결합금의 오스테나이트 안정성)

  • Choi, Seunggyu;Seo, Namhyuk;Jun, Junhyub;Son, Seung Bae;Lee, Seok-Jae
    • Journal of Powder Materials
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    • v.27 no.5
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    • pp.414-419
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    • 2020
  • In the present study, we investigated the austenite stability of a sintered Fe-based nanocrystalline alloy. The volume fraction of austenite was measured based on the X-ray diffraction data of sintered Fe-based nanocrystalline alloys, which were prepared by high-energy ball milling and spark plasma sintering. The sintered alloy samples showed a higher volume fraction of austenite at room temperature as compared to the equilibrium volume fraction of austenite obtained using thermodynamic calculations, which resulted from the nanosized crystalline structure of the sintered alloy. It was proved that the austenite stability of the sintered Fe-based alloy increased with a rise in the amount of austenite stabilizing elements such as Mn, Ni, and C; however, it increased more effectively with a decrease in the actual grain size. Furthermore, we proposed a new equation to predict the martensite starting temperature for sintered Fe-based alloys.