• 제목/요약/키워드: University IT Research Center

검색결과 12,480건 처리시간 0.058초

The Effects of Resveratrol on Silica-Induced Lung Oxidative Stress and Inflammation in Rat

  • Maryam Esfahani;Amir Hossein Rahbar;Sara Soleimani Asl;Saed Bashirian;Effat Sadat Mir Moeini;Fereshteh Mehri
    • Safety and Health at Work
    • /
    • 제14권1호
    • /
    • pp.118-123
    • /
    • 2023
  • Background: Chronic exposure to silica is related with the provocation of an inflammatory response and oxidative stress mechanism. Vitamin D has multiple benefits in biological activities particularly respiratory system disease. Method: In this research, 20 male Wistar rats were randomly allocated into four groups (5 rats /group) as follow: Group1 received saline as (negative control) group. The group 2 received a single IT instillation of silica (positive control) group; the group 3 was co-administrated with single IT silica and Vitamin D (20 mg/kg/day) daily for a period of 90 days. The rats of group 4 received Vitamin D daily for a period of 90 days. Results: Silica significantly increased serum and lung total Oxidant Status (TOS). Meanwhile, silica reduced serum and lung total antioxidant capacity (TAC), GSH and tumor necrosis factor-α (TNF-a). Vitamin D treatment meaningfully reversed oxidative stress, antioxidants status and inflammatory response. Also, Vitamin D improved histopathological changes caused by silica. Conclusion: These findings indicate that Vitamin D exerts protective effects against silica-induced lung injury. It seems that Vitamin D has potential use as a therapeutic object for silica induced lung injure.

Color Filter Pattern Generation by Screen Printing

  • Choi, Yong-Jung;Lee, Taik-Min;Nam, Soo-Yong;Kim, Yong-Sung;Na, Dae-Yup;You, Choon-Woo;Shin, Dong-Youn;Kim, Kwang-Young;Jung, Kwang-Il
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권1호
    • /
    • pp.380-383
    • /
    • 2007
  • In this research, we present color filter which is patterned by screen printing method. Analysis of screen printing process, screen printing system, experiment for uniform printing in large area, characteristics of screen printed CF are investigated .In spite of limitation of precision, screen printed color filter is very cost- effective in respect of manufacturing facility and ink usage.

  • PDF

Gram-Positive Bacteria Specific Properties of Silybin Derived from Silybum marianum

  • Lee, Dong-Gun;Kim, Hyung-Keun;Park, Yoon-Kyung;Park, Seong-Cheol;Woo, Eun-Rhan;Jeong, Hye-Gwang;Hahm, Kyung-Soo
    • Archives of Pharmacal Research
    • /
    • 제26권8호
    • /
    • pp.597-600
    • /
    • 2003
  • Silybin has a potent antibacterial activity, more potent than silymarin II, against gram-positive bacteria without hemolytic activity, whereas it has no antimicrobial activity against gram-negative bacteria or fungi. The mode of action of silybin against the gram-positive bacterial cell was examined by investigating the change in plasma membrane dynamics of bacterial cells using 1 ,6-diphenyl-1,3,5-hextriene (DPH) as a membrane probe and by assessing the inhibition of macromolecular synthesis using radiolabeled incorporation assay. The results showed that silybin inhibited RNA and protein synthesis on gram-positive bacteria.

최근 핵의학 영상 기기 발전 동향 (Recent Developments in Nuclear Medicine Instrumentation)

  • 김준영;최용;김종호;임기천;최연성;이경한;김상은;김병태
    • 대한핵의학회지
    • /
    • 제32권6호
    • /
    • pp.471-481
    • /
    • 1998
  • The goals of developments in nuclear medicine instrumentation are to offer a higher-quality image and to aid diagnosis, prognosis assessment or treatment planning and monitoring. It is necessary for physicists and engineers to improve or design new instrumentation and techniques, and to implement, validate, and apply these new approaches in the practice of nuclear medicine. The researches in physical properties of detectors and crystal materials and advances in image analysis technology have improved quantitative and diagnostic accuracy of nuclear medicine images. This review article presents recent developments in nuclear medicine instrumentation, including scatter and attenuation correction, new detector technology, tomographic image reconstruction methods, 511 keV imaging, dual modality imaging device, small gamma camera, PET developments, image display and analysis methods.

  • PDF

A Subthreshold Slope and Low-frequency Noise Characteristics in Charge Trap Flash Memories with Gate-All-Around and Planar Structure

  • Lee, Myoung-Sun;Joe, Sung-Min;Yun, Jang-Gn;Shin, Hyung-Cheol;Park, Byung-Gook;Park, Sang-Sik;Lee, Jong-Ho
    • JSTS:Journal of Semiconductor Technology and Science
    • /
    • 제12권3호
    • /
    • pp.360-369
    • /
    • 2012
  • The causes of showing different subthreshold slopes (SS) in programmed and erased states for two different charge trap flash (CTF) memory devices, SONOS type flash memory with gate-all-around (GAA) structure and TANOS type NAND flash memory with planar structure were investigated. To analyze the difference in SSs, TCAD simulation and low-frequency noise (LFN) measurement were fulfilled. The device simulation was performed to compare SSs considering the gate electric field effect to the channel and to check the localized trapped charge distribution effect in nitride layer while the comparison of noise power spectrum was carried out to inspect the generation of interface traps ($N_{IT}$). When each cell in the measured two memory devices is erased, the normalized LFN power is increased by one order of magnitude, which is attributed to the generation of $N_{IT}$ originated by the movement of hydrogen species ($h^*$) from the interface. As a result, the SS is degraded for the GAA SONOS memory device when erased where the $N_{IT}$ generation is a prominent factor. However, the TANOS memory cell is relatively immune to the SS degradation effect induced by the generated $N_{IT}$.

Investigation of Frequency Dependent Sensitivity of Noise Figure on Device Parameters in 65 nm CMOS

  • Koo, Min-Suk;Jung, Hak-Chul;Jhon, Hee-Sauk;Park, Byung-Gook;Lee, Jong-Duk;Shin, Hyung-Cheol
    • JSTS:Journal of Semiconductor Technology and Science
    • /
    • 제9권1호
    • /
    • pp.61-66
    • /
    • 2009
  • We have investigated the noise sensitivity of low noise amplifier (LNA) at different frequency. This noise sensitivity analysis provides insights about noise parameters and it is very beneficial for making appropriate design trade-offs. From this work, the circuit designer can choose the adequate noise parameters tolerances.

High Power Inverter for LCD Backlight Driving

  • Hur, Jeong-Wook;Kim, Tae-Jo;Lim, Sung-Kyoo
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 한국정보디스플레이학회 2000년도 제1회 학술대회 논문집
    • /
    • pp.91-92
    • /
    • 2000
  • A high power inverter with 300:1 dimming capability for high luminance, one cell, Osram Planon type, plasma light source for LCD Backlight was designed and tested. It was possible to achieve 300:1 dimming control

  • PDF

실험 환경에 따른 LFM 성능 분석에 관한 연구 (A Study of Performance Analysis of LFM According to Experimental Environment)

  • 김성호;김세연;박정은;고학림;김계원;이호준
    • 한국정보처리학회:학술대회논문집
    • /
    • 한국정보처리학회 2023년도 추계학술발표대회
    • /
    • pp.1237-1239
    • /
    • 2023
  • 본 논문에서는 Linear Frequency Modulation(LFM)을 이용하여 실해역에서 실험을 진행하였다. LFM 이란 시간에 따라 주파수가 변화하는 Chirp 신호를 전송하는 통신 기법이며 성능 분석을 위해 대한민국의 한강, 서해, 남해에서 각각 실험을 진행하였다. LFM 신호의 중심 주파수는 34kHz 대역폭은 1kHz로 설정하여 실험을 진행하였으며 채널 환경 분석을 위한 5초 길이의 Tone 신호를 함께 송·수신 하였다. 실험 결과 세 곳의 실험 포인트 모두에서 송·수신 신호 간의 뚜렷한 상호상관 결과를 확인할 수 있었다.

백악질 열리의 임상 증례 (Clinical case reports of cemental tear)

  • 박정철;백도영;김창성;조규성;채중규;김종관;최성호
    • Journal of Periodontal and Implant Science
    • /
    • 제38권3호
    • /
    • pp.551-556
    • /
    • 2008
  • Purpose: Cemental tear is an uncommon form of root fracture that can lead to rapid localized attachment loss. When it is exposed in the periodontal pocket, it should be removed to prevent accumulation of dental plaque and calculus. Material and Methods: 2 patients were diagnosed as a cemental tear and they were treated with conventional flap operation and subgingival curettage. Additional treatments such as bone graft or guided tissue regeneration were not performed. Result: Symptoms subsided after the treatment. Periodontal pocket has been reduced but no gain of clinical attachment was observed. Remnant of cemental fragment remained after curettage. However, periodontal pocket was stably maintained and there was no recurrence. Conclusion: Periodontal attachment loss associated with cemental tear can be successfully treated with conventional periodontal surgical and nonsurgical procedures.