• Journal of Computational Design and Engineering
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• v.3 no.4
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• pp.385-397
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• 2016

Scaffolds are essential in bone tissue engineering, as they provide support to cells and growth factors necessary to regenerate tissue. In addition, they meet the mechanical function of the bone while it regenerates. Currently, the multiple methods for designing and manufacturing scaffolds are based on regular structures from a unit cell that repeats in a given domain. However, these methods do not resemble the actual structure of the trabecular bone which may work against osseous tissue regeneration. To explore the design of porous structures with similar mechanical properties to native bone, a geometric generation scheme from a reaction-diffusion model and its manufacturing via a material jetting system is proposed. This article presents the methodology used, the geometric characteristics and the modulus of elasticity of the scaffolds designed and manufactured. The method proposed shows its potential to generate structures that allow to control the basic scaffold properties for bone tissue engineering such as the width of the channels and porosity. The mechanical properties of our scaffolds are similar to trabecular tissue present in vertebrae and tibia bones. Tests on the manufactured scaffolds show that it is necessary to consider the orientation of the object relative to the printing system because the channel geometry, mechanical properties and roughness are heavily influenced by the position of the surface analyzed with respect to the printing axis. A possible line for future work may be the establishment of a set of guidelines to consider the effects of manufacturing processes in designing stages.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.766-768
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• 2004

Rubbed films of a series of poly(p-phenylene 3,6-bis(4-(n-alkyloxy)phenyloxy)pyromellitimide)s (Cn-PMDA-PDA PIs), which are well-defined brush PIs composed of two aromatic-aliphatic bristles per repeat unit of a fully rodlike backbone, were investigated in detail using atomic force microscopy (AFM), optical retardation analysis and linearly polarized infrared (IR) spectroscopy in order to elucidate their surface morphology and molecular orientation. The liquid crystal (LC) alignment behavior and the anchoring energy of LC molecules on the rubbed films were also determined.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.2
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• pp.115-125
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• 2012

Application of the Object-oriented Programming (OOP) method to the Finite Element Model (FEM) program has various strengths including the features of encapsulation, polymorphism and inheritance. However, this technique should be based upon a premise that the independency of the object method and data to be used is guaranteed. By attempting to apply the OOP to the FEM, existing researches go against the independency of the OOP which is an essential feature of the method. The reason is this: existing researches apply the OOP to modules in accordance with analysis procedures, although the data to be used is classified as an element unit in the FEM. Therefore, the required independency cannot be maintained as whole stiffness matrices and boundary conditions are combined together. Also, solutions are sought from analysis module after data is regrouped at the pre-processor, and their results are analyzed during the post-processor. As this is similar to a batch processing, it cannot use data at analysis, and recalculation should be done from the beginning if any condition is changed after the analysis is complete, which are limitations of the existing researches. This research implemented the Object-orientation of elements so that the three features of the OOP (i.e. encapsulation, polymorphism and inheritance) can be guaranteed and their independency maintained as a result. For this purpose, a model called 'Object-oriented Finite element Model ensuring the Independency of Elements (OFMIE)', which enables the analysis of targets through mutual data exchanges within instance, was developed. In conclusion, the required independency was achieved in the instance of the objected elements and the analysis results of previous conditions could be used for the analysis after changes. The number of repetitive calculations was reduced by 75 per cent through this gradual analysis processes.

• The Journal of the Korea Contents Association
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• v.9 no.11
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• pp.289-296
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• 2009

In this study, I presented power control unit with potential use in the magnetic stimulation of biological systems. The effect of the magnetic stimulation depends on the geometry and orientation of the induced electric field as well as on the current pulse waveform delivered by the stimulator coil. TMS is achieved from the outside of the head using pulses of electromagnetic field that induce an electric field in the brain. There are numerous possibities in the applications TMS, such as diagnosis and therapy through the brain stimulation. These factors are very important to define the equipment requirements and characteristics in that the topology of the power supply and the size and geometry of the coil. The proposed solution is the generation of current pulses with variable amplitude and duration, according to a user defined input. Another solution is the topology that uses elements to store and transfer energy from the power source to the load. In addition to proposed topology, an adequate control strategy and right set of the power circuit parameters made possible to obtain unipolar waves and bipolar waves.

• The Journal of the Korea Contents Association
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• v.18 no.10
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• pp.134-144
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• 2018

The purpose of this study was to examine the effects of delirium prevention program in patients after hip joint surgey. A non equivalent control group post-test only design was utilized. Sixty four patients aged 65 and older who admitted to a surgical intensive care unit after hip joint surgery were assigned to either a experimental group (n=33) or a control group (n=31). The experimental group was provided with delirium prevention program consisting of orientation intervention, activity intervention, physiological intervention, nutritional intervention, sleep intervention, environmental intervention. Data were analyzed using ${\chi}^2-test$ and independent t-test. The experimental group showed lower incidence of delirium than the control group(${\chi}^2=7.048$, p=.008). The experimental group showed lower ICU stay and length of hospitalization than the control group although the difference was not statistically significant. Findings indicate that the dilirium prevention program is effective in reducing incidence of delirium in patients after hip joint surgery and delirium prevention program is recommended as a guide for the prevention of delirium.

• Composites Research
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• v.30 no.4
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• pp.247-253
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• 2017

In this study, the mechanical behavior and interface properties of boron nitride nanotube-poly(methyl methacrylate) nanocomposites are predicted using the molecular dynamics simulations and the double inclusion model. After modeling nanocomposite unit cell embedding single-walled nanotube and polymer, the stiffness matrix is determined from uniaxial tension and shear tests. Through the orientation average of the transversely isotropic stiffness matrix, the effective isotropic elastic constants of randomly dispersed microstructure of nanocomposites. Compared with the double inclusion model solution with a perfect interfacial condition, it is found that the interface between boron nitride nanotube and polymer matrix is weak in nature. To characterize the interphase surrounding the nanotube, the two step domain decomposition method incorporating a linear spring model at the interface is adopted. As a result, various combinations of the interfacial compliance and the interphase elastic constants are successfully determined from an inverse analysis.

• Korean Journal of Adult Nursing
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• v.22 no.4
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• pp.375-383
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• 2010

Purpose: The purpose of this study was to examine if simulation training affects new graduate critical care nurses' knowledge, self-efficacy, and performance ability in emergency situations. Methods: Forty new graduate critical care nurses were randomly assigned to either an experimental or a control group. The experimental group had didactic with simulation. The control group received only didactic without simulation about emergency situations. The data were collected before and after the training interventions. An independent t-test used for difference among variables. Results: There were no significant demographic differences between the two groups or any differences on data collected knowledge, self-efficacy and performance ability. Following the training, there were significant performance ability scores (p<.001) among the nurses receiving didactic with simulation. There were no significant difference between the two groups relative to knowledge scores (p=.117), or the self-efficacy scores (p=.100). Conclusion: This study showed that simulation training for new graduate critical care nurses is useful to improve performance ability on emergency situations. Hence, providing simulation training to critical care nurses during an orientation period would improve quality of critical care nursing and help the new graduates nurse's adaptation.

• Journal of Korean Home Economics Education Association
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• v.12 no.3
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• pp.19-38
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• 2000

This study is about open and secondary level Home Economics Education which is applicable to field and which includes the characteristics, purpose and problems of each open education, secondary education and home economics education. Based on the ideology of open education this study will identify the meaning of openness in terms of Home Economics Education reconstructing meaning purpose, characteristics, curriculum paradigm and curriculum. The instructional model and module which use web, will be presented as the results o the reconstruction works. The open instructional module in Home Economics Education which will be operated on the web is consisted of 1) setting the orientation of curriculum development 2) instructional model development 3) rebuilding the Home Economics Education curriculum 4)development of instructional modules and web-based materials and 5)construction of the web-site. Six instructional module begin with critical/emancipatory curriculum paradigm in open Home Economics Education use module as a unit of class management instead of 1 class, facilitates nest-type integration which is applied from open education keeping the nature of Home Economics Education and focus on practical problem and problem solving through reconceptualization with dialectical perspective on individual, family and society. The practical problem solving model has four steps: Identifying practical problems. Understanding the contexts of problem, Searching for solutions and examining its consequences, Action and evaluation. The web-site has to be developed based on the six instructional module includes those issues : self-identification for reinforcing autonomy and self-esteem, living with family living with friends, autonomous living healthy living and understanding sexuality.

• Journal of Microbiology and Biotechnology
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• v.30 no.11
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• pp.1750-1759
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• 2020

The characterization of cytochrome P450 CYP125A13 from Streptomyces peucetius was conducted using cholesterol as the sole substrate. The in vitro enzymatic assay utilizing putidaredoxin and putidaredoxin reductase from Pseudomonas putida revealed that CYP125A13 bound cholesterol and hydroxylated it. The calculated K_D value, catalytic conversion rates, and Km value were 56.92 ± 11.28 μM, 1.95 nmol min^-1 nmol^-1, and 11.3 ± 2.8 μM, respectively. Gas chromatography-mass spectrometry (GC-MS) analysis showed that carbon 27 of the cholesterol side-chain was hydroxylated, characterizing CYP125A13 as steroid C27-hydroxylase. The homology modeling and docking results also revealed the binding of cholesterol to the active site, facilitated by the hydrophobic amino acids and position of the C27-methyl group near heme. This orientation was favorable for the hydroxylation of the C27-methyl group, supporting the in vitro analysis. This was the first reported case of the hydroxylation of cholesterol at the C-27 position by Streptomyces P450. This study also established the catalytic function of CYP125A13 and provides a solid basis for further studies related to the catabolic potential of Streptomyces species.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.921-924
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• 2008

Several techniques, including transmission X-ray photography and AC-impedance spectroscopy, are available for evaluating the fiber dispersion in a fiber reinforced concrete Evaluating the fiber dispersion in fiber reinfored concrete needs since the fibers bridge crackseffectively. However, these equipment is very expensive. Therefore this paper presents the quantitative evaluation method based on the image analysis of sectional image taken using an ordinary digital camera. After detecting the fiber accurately, the fiber dispersion characteristics are represented by the coefficient such as the fiber dispersion coefficient, the number of fibers in unit area, and the distribution of the fiber orientation. Test were performed to evaluate the effectiveness of proposed method and the dispersion characteristics of fibers according placing method and flow direction. Additionally, the effect of fiber dispersion characteristics on mechanical properties was investigated. Test results shows that fiber aligned along the flow direction and more fibers placed and dispersion was better on the section parallel to the flow direction. And about 50% difference in the flexural tensile strength according to the placing method occured.