• Journal of the Korean Society of Safety
• /
• v.9 no.3
• /
• pp.3-12
• /
• 1994

This study employed the Eshelby's equivalent inclusion method incorporated with mean field theory to investigate the Internal stress of short fiber-reinforced metal matrix composites during static loading and the dynamic finite element analysis by using alternative unit cell model to investigate the impact behaviors during the impact loading. Using the 2124 Al-SiC system as an example, the general effects of parameters such as fiber's aspect ratio, content and modulus were examined.

• Fibers and Polymers
• /
• v.5 no.3
• /
• pp.182-186
• /
• 2004

The effect of braid construction parameters on yarn cross-sectional shape is presented in this paper. The location of the yam within the braid unit cell is quantified by a compaction factor. A range of braided fabrics were produced and optically measured for actual yarn cross-sectional shape. A comparison of the theoretical and experimental values shows good correlation. Design curves can be produced with the developed model to allow selection of appropriate braid process parameter to create yarns with desired cross-sectional geometries.

• Journal of the Korea Convergence Society
• /
• v.7 no.4
• /
• pp.181-190
• /
• 2016

The objective of this study is to find the effective stiffness and compressive strengths of a unit-cell pinwheel truss and double pinwheel truss model designed following a double helical geometry similar to that of the DNA (deoxyribonucleic acid) structure in biology. The ideal solution for their derived relative density is correlated with a ratio of the truss thickness and length. To validate the relative stiffness or relative strength, ABAQUS software is used for the computational model analysis on five models having a different size of truss diameter from 1mm to 5mm. Applied material properties are stainless steel type 304. The boundary conditions applied were fixed bottom and 5 mm downward displacement. It was assumed that the width, length, and height are all equal. Consequently, it is found that the truss model has a lower effective stiffness and a lower effective yielding strength.

• Journal of Korean Medical classics
• /
• v.19 no.3
• /
• pp.165-183
• /
• 2006

A study of scientific methods in a study of comparative on the oriental medicine and the western medicine evidence to find on the cause-effect relationship. The rationality in a study of process and the confidence in a study of result were improved by a study of methods on the cause-effect relationship. Also a comparative study on the Jeong(精) of the oriental medicine and the cell of the western medicine, after established a model of the cause-effect relationship secured a suitability of a comparative subject and operationalization of a comparative variable to the rationality in a study of process. The Jeong(精) and the cell are the character of a unit and the character of a matter on the human body. The Jeong(精) and the cell are a point of similarity in the function. The Jeong(精) and the cell are a relation in the mechanism. Our paper reviewed a study of comparative methods on the oriental medicine and the western medicine, and suggest an identic interpretation on the human body.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.41 no.6
• /
• pp.91-98
• /
• 2004

This paper proposes a PCB plane model for generic SPICE circuit simulators. The proposed model reflects two frequency-dependent losses, namely skin and dielectric losses. After power/ground plane pair is divided into arrays of unit-cells, each unit-cell is modeled using a transmission line and two loss models. The loss model is composed of a resistor for DC loss, series HL ladder circuit for skin loss and series RC ladder circuit for dielectric loss. To verify the validity of the proposed model, it is compared with SPICE ac analysis using frequency-dependent resistors. Also, we show that the estimation results using the proposed model have a good correlation with that of VNA measurement for the typical PCB stack-up structure of general desktop PCs. With the proposed model, not only ac analysis but also transient analysis can be easily done for circuits including various non-linear/linear devices since the model consists of passive elements onl.

• The Korean Journal of Pain
• /
• v.35 no.3
• /
• pp.271-279
• /
• 2022

Background: Inflammation is known to underlie the pathogenesis in neuropathic pain. This study investigated the anti-inflammatory and neuroprotective mechanisms involved in antinociceptive effects of co-administration of acetaminophen and L-carnosine in chronic constriction injury (CCI)-induced peripheral neuropathy in male Wistar rats. Methods: Fifty-six male Wistar rats were randomly divided into seven experimental groups (n = 8) treated with normal saline/acetaminophen/acetaminophen + L-carnosine. CCI was used to induce neuropathic pain in rats. Hyperalgesia and allodynia were assessed using hotplate and von Frey tests, respectively. Investigation of spinal proinflammatory cytokines and antioxidant system were carried out after twenty-one days of treatment. Results: The results showed that the co-administration of acetaminophen and L-carnosine significantly (P < 0.001) increased the paw withdrawal threshold to thermal and mechanical stimuli in ligated rats compared to the ligated naïve group. There was a significant (P < 0.001) decrease in the levels of nuclear factor kappa light chain enhancer B cell inhibitor, calcium ion, interleukin-1-beta, and tumour necrotic factor-alpha in the spinal cord of the group coadministered with acetaminophen and L-carnosine compared to the ligated control group. Co-administration with acetaminophen and L-carnosine increased the antioxidant enzymatic activities and reduced the lipid peroxidation in the spinal cord. Conclusions: Co-administration of acetaminophen and L-carnosine has anti-inflammatory effects as a mechanism that mediate its antinociceptive effects in CCI-induced peripheral neuropathy in Wistar rat.

• Korean Journal of Food Science and Technology
• /
• v.37 no.2
• /
• pp.194-198
• /
• 2005

Growth curves of Listeria monocytogenes in modified surimi-based imitation crab (MIC) broth were obtained by measuring cell concentration in MIC broth at different culture conditions [initial cell numbers, $1.0{\times}10^{2},\;1.0{\times}10^{3}\;and\;1.0{\times}10^{4}$, colony forming unit (CFU)/mL; temperature, 15, 20, 25, 37, and $40^{\circ}C$] and applied to Gompertz model to determine microbial growth indicators, maximum specific growth rate constant (k), lag time (LT), and generation time (GT). Maximum specific growth rate of L. monocytogenes increased rapidly with increasing temperature and reached maximum at $37^{\circ}C$, whereas LT and GT decreased with increasing temperature and reached minimum at $37^{\circ}C$. Initial cell number had no effect on k, LT, and GT (p > 0.05). Polynomial and square root models were developed to express combined effects of temperature and initial cell number using Gauss-Newton Algorism. Relative coefficients of experimental k and predicted k of polynomial and square root models were 0.92 and 0.95, respectively, based on response surface model. Results indicate L. monocytogenes growth was mainly affected by temperature and square root model was more effective than polynomial model for growth prediction.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.17 no.3
• /
• pp.458-464
• /
• 2017

A magnetic tunnel junction (MTJ) based ternary content addressable memory (TCAM) is proposed which provides non-volatility. A unit cell of the TCAM has two MTJ's and 4.875 transistors, which allows the realization of TCAM in a small area. The equivalent resistance of parallel connected multiple unit cells is compared with the equivalent resistance of parallel connected multiple reference resistance, which provides the averaging effect of the variations of device characteristics. This averaging effect renders the proposed TCAM to be variation-tolerant. Using 65-nm CMOS model parameters, the operation of the proposed TCAM has been evaluated including the Monte-Carlo simulated variations of the device characteristics, the supply voltage variation, and the temperature variation. With the tunneling magnetoresistance ratio (TMR) of 1.5 and all the variations being included, the error probability of the search operation is found to be smaller than 0.033-%.

• Proceedings of the Korean Society For Composite Materials Conference
• /
• 2002.10a
• /
• pp.68-70
• /
• 2002

Prediction of 3-D permeability tensor for multi-axial preform is critical to model and design the manufacturing process of composites by considering resin flow through the multi-axial fiber structure. In this study, the in-plane and transverse permeabilities for braided preform are predicted numerically. The flow analyses are calculated by using 3-D CVFEM(control volume finite element method) for macro-unit cells. To avoid checker-board pressure field and improve the efficiency of numerical computation, a new interpolation function for velocity is proposed on the basis of analytic solutions. Permeability of a braided preform is measured through unidirectional flow experiment and compared with the permeability calculated numerically. Unlike other studies, the current study is based on more realistic unit cell and prediction of permeability is improved.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.7
• /
• pp.3213-3222
• /
• 2016

Background: Methyl donor status influences DNA stability and DNA methylation although little is known about effects on DNA methyltransferases. The aim of this study was to determine whether methyl-donor status influences DNA methyltransferase (Dnmt) gene expression in cervical cancer cells, and if so, whether there are associated effects on global DNA methylation. Materials and Methods: The human cervical cancer cell line, C4-II, was grown in complete medium and medium depleted of folate (F-M+) and folate and methionine (F-M-). Growth rate, intracellular folate, intracellular methionine and homocysteine in the extracellular medium were measured to validate the cancer cell model of methyl donor depletion. Dnmt expression was measured by qRT-PCR using relative quantification and global DNA methylation was measured using a flow cytometric method. Results: Intracellular folate and methionine concentrations were significantly reduced after growth in depleted media. Growth rate was also reduced in response to methyl donor depletion. Extracellular homocysteine was raised compared with controls, indicating disturbance to the methyl cycle. Combined folate and methionine depletion led to a significant down-regulation of Dnmt3a and Dnmt3b; this was associated with an 18% reduction in global DNA methylation compared with controls. Effects of folate and methionine depletion on Dnmt3a and 3b expression were reversed by transferring depleted cells to complete medium. Conclusions: Methyl donor status can evidently influence expression of Dnmts in cervical cancer cells, which is associated with DNA global hypomethylation. Effects on Dnmt expression are reversible, suggesting reversible modulating effects of dietary methyl donor intake on gene expression, which may be relevant for cancer progression.