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검색결과 821건 처리시간 0.025초

LC-MS/MS 및 ICP를 이용한 당뇨환의 화학적 특성 분석 (Characteristic Effects of Dangnyo-hwan for Diabetes Control Studied Using LC-MS/MS and ICP)

  • 인정도;임대식;문승호;김원일
    • 대한한방내과학회지
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    • 제36권3호
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    • pp.217-227
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    • 2015
  • Objectives: The primary aim of this study was to identify bioactive compounds in Dangnyo-hwan, a Korean herbal medicine, through instrumental analysis using LC-MS/MS and ICP, and investigate its potential use in diabetes treatment. Methods: The extract of Dangnyo-hwan has 12 medicinal herbs; these were compared with 18 marker substances selected from literature survey. Results: LC-MS/MS analysis could detect 9 of the 18 bioactive compounds: citruline, catalpol, berberine, ginsenoside Rb1, ginsenoside Rg1, oleanolic acid, β-sitosterol, mangiferin, and schizandrin. While harmful heavy metals such as As, Pb, Cd, Hg, Ni, and Cu were not present in high concentrations, Zn concentration was 4.2 mg in 100 g Dangnyo-hwan. Conclusions: Instrumental analysis such as LC-MS/MS and ICP was successfully used to identify bioactive compounds in Dangnyo-hwan. Detection of 9 bioactive substances and Zn from the herb medicine is a valuable finding, and suggests that Dangnyo-hwan is a candidate medicine for diabetes. Further investigations like in vitro assay, percent GPR 119 activity, and percent human DGAT-1 inhibition are underway.

Nondestructive Evaluation Technology and Reliability of Products

  • Lee, Joon-Hyun;Lee, Seung-Suck
    • 한국신뢰성학회:학술대회논문집
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    • 한국신뢰성학회 2001년도 정기학술대회
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    • pp.235-238
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    • 2001
  • It is well known that the reliability of materials of mechanical products is becoming more and more important not only for assurance of quality, but for international competition of products. In order to assure the reliability of materials or mechanical products nondestructive evaluation (NDE) techniques are playing more important roles. The existence of Internal defects in materials or mechanical parts is served as crack initiation site during the various loading condition. Historically, nondestructive evaluation (NDE) technique has been used almost exclusively for detecting microscopic discontinuities In materials or mechanical parts after they have been in service to expand the role of the NDE to include all aspects of materials production and application. Research efforts are being directed at developing and perfecting NDE techniques capable of monitoring (1) materials production processes (2) material integrity following transport, storage and fabrication and (3) the amount and rate of degradation during service. In addition, efforts are underway to develop technique capable of quantitative discontinuity sizing, permitting determination of response using fracture mechanics analysis, as well as techniques for quantitative materials characterization to replace the qualitative techniques used in the past. In this paper, the important role of NDE technology for reliability assurance of materials/mechanical parts is introduced.

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연구로 해체정보 관리를 위한 데이터베이스 시스템 개발 (Development of the Database System for Managing Decommissioning Information from Research Reactor)

  • 정관성;이동규;박희성;이근우;오원진
    • 한국방사성폐기물학회:학술대회논문집
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    • 한국방사성폐기물학회 2004년도 학술논문집
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    • pp.58-71
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    • 2004
  • 연구용원자로를 해체하는 과정에서 발생되는 각종 자료들은 여러 장소에서 상호 호환성 없는 형태로 발생하므로 관리와 활용이 용이하지 않다. 연구로 1, 2호기를 해체하면서 발생되는 자료를 해체시설, 해체작업, 방사선학적 그리고 해체폐기물 정보영역별로 분류하여 자료를 관리하고 보다 객관적이고 정확한 정보 분석이 가능하도록 데이터베이스 시스템을 개발하였다. 연구용 원자로 해체활동 자료에 대한 체계가 구축됨으로써 해체사업을 보다 더 효율적으로 수행하는 데 도구로 활용할 수 있을 것이다. 해체 현장 자료 입력, 분석 및 평가를 통하여 연구로 1, 2호기 해체활동 자료에 대하여 보다 객관적이고 정확한 평가가 가능하게 되었고, 이를 바탕으로 연구로 1, 2호기 해체프로젝트를 보다 효율적으로 수행할 수 있게 될 것이다.

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Characterization of A cDNA encoding A Novel Phenazine Compound in Hot Pepper

  • Kim, Ukjo;Lee, Sang-Jik;Lee, Mi-Yeon;Park, Soon-Ho;Yang, Seung-Gyun;Harn, Chee-Hark
    • 한국식물병리학회:학술대회논문집
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    • 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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    • pp.109.1-109
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    • 2003
  • From the PMMV (pepper mild mottle virus)-inducible ESTs differentially expressed in Capsicum chinense PI257284, we isolated a full-length cDNA (CcPHZF: Capsicum chinense phenazine), encoding a phenazine biosynthesis protein which catalyzes the hydroxylation of phenozine-1-carboxylic acid to 2-hydroxyphenazine-1-carboxylic acid. Phenazine compound has been known to exhibit broad-spectrum of antibiotic activity against various species of bacteria and fungus. The entire region of CcPHZF is 879 bp in length and the open reading frame predicted a polypeptide of 292 amino acids. The homolog of CcPHZF is not Present in database except clones of AC004044 and NM100203 from Arabidopsis with 58 and 59%, respectively. Genomic Southern analysis indicated that the pepper genome contains a single copy of CcPHZF. The CcPHZF was strongly induced in the pepper leaves 3 days after PMMV treatment, when HR occurs on the leaf surface. Characterization of CcPHZF is underway to investigate if the CcPHZF is related to disease resistance against pathogens.

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SPC관련 KS의 제개폐 및 KS A ISO 2859-3에 대한 고찰 (A Study on SPC-related KS and KS A ISO 2859-3)

  • 임재근;조병선;정수일
    • 산업경영시스템학회지
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    • 제28권2호
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    • pp.75-80
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    • 2005
  • As a result of globalization process and TBT agreement, KS is also being revised, reestablished and some are abolished according to international standards such as ISO, IEC, etc. Conventional KS sampling inspection standards contained many different procedures from ISO, but recently, to match with international standards, all the rest of the standards except KS A 3102, 3104, 3151 were abolished, and the even the ones being in use still are also scheduled and be revised. Especially, KS A 3101, KS A 3105, KS A 3109, which were used most frequently in Korea were abolished, and the KS A ISO $2859-0\~3$ which coincide with ISO standards were established 3 years ago, but the implementation rate is very slow. Starting next year the national examination for qualification process for the product quality related item will the started and the preparation is underway. This study will investigate the recent sampling inspection process of KS as well as SPC related KS overhaul problem and present the data to help workers in SPC related field. One of the main example will be on KS A ISO 2859-3 and will attempt to help those medium and small sized companies with examples.

주파수 공동사용 정책 및 표준화 동향 (Spectrum Policy and Standardization Trends on Frequency Sharing)

  • 강규민;박재철;최수나;유성진;황성현;변우진
    • 전자통신동향분석
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    • 제33권3호
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    • pp.1-10
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    • 2018
  • This article presents spectrum sharing policy trends both overseas and domestically. The Federal Communications Commission recently adopted rules for the commercial use of a 150 MHz bandwidth at 3.55 to 3.7 GHz, which has been utilized for defense and satellite services. This frequency band for spectrum sharing is called the citizens broadband radio service (CBRS) band. In Europe, the related regimes for licensed shared access application at 2.3 to 2.4 GHz has been organized, and interface standardization for sharing frequency information has been completed. In Korea, efforts are being made to establish spectrum-sharing policies to improve the efficiency of the frequency utilization. This article also introduces both the IEEE 802 local area network/metropolitan area network and 3GPP standardization activities with regard to frequency sharing technologies. To effectively solve the spectrum-sharing problem in IEEE 802, standardization activities on the CBRS and the mid-band (3.7-24 GHz) are underway. 3GPP is currently developing the standardization of a licensed assisted access technology, which extends mobile communication services provided in the licensed band to unlicensed bands.

A Study on the Situation of Safety Management in Central African Construction Sites - Focusing on DR Congo and Rwanda -

  • Bitamba, Bauma Frigeant;An, Sung-Hoon
    • 한국건축시공학회지
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    • 제18권4호
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    • pp.395-401
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    • 2018
  • The Central African Region is known as one of the most troubled and unsafe regions in Africa. But more recently the Central African Region has been growing and developing, with many projects underway involving huge local and foreign construction companies. Despite this fact, workers in the Central African Region often encounter unsafe working conditions and must confront many kinds of hazards. Therefore, the aim of this study is to identify the safety management situation in Central African construction sites, by focusing on the countries of Rwanda and DR Congo. Through our research, it was found that the two countries studied in the Central African Region are very similar with regard to their safety management systems, with some exceptions. In addition, it was revealed that both these countries in the Central African Region had good safety performance. This study will help to illuminate the situation of safety systems on construction sites in the Central African Region, and can be used by companies advancing into the Central African Region's construction market.

형틀 목공이 사용하는 작업공구와 근골격계 질환의 상관관계 분석 (Mold Woodworking Tools and musculoskeletal disorders of the correlation analysis)

  • 곽동진;박정로;김재준
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2012년도 추계 학술논문 발표대회
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    • pp.5-7
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    • 2012
  • Repeated using carpentry workers work at working tools because of occupational low back pain, such as musculoskeletal disorders, occupational diseases are on the rise. For this purpose, through the analysis of musculoskeletal disorders and work tools and studies are underway to improve the working conditions of the workers. However, existing previous studies may not reflect the working tools used for carpentry worker dies when working at a construction site that Therefore, in this study, the work in the form of construction, one of the jobs of worker dies classified according to the working tools of musculoskeletal disorders correlated to analyze. The results of this study are as follows. working tools of a total of seven different dies used in the installation process. Musculoskeletal disorders, waist / drill such correlation was very strong. Also showed that a total of three of the tools used in the formwork dismantling cutter musculoskeletal disorders of the arm / elbow and a very strong correlation.

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3D 바이오 프린팅 기술 현황과 응용 (Status and Prospect of 3D Bio-Printing Technology)

  • 김성호;여기백;박민규;박종순;기미란;백승필
    • KSBB Journal
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    • 제30권6호
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    • pp.268-274
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    • 2015
  • 3D printing technology has been used in various fields such as materials science, manufacturing, education, and medical field. A number of research are underway to improve the 3D printing technology. Recently, the use of 3D printing technology for fabricating an artificial tissue, organ and bone through the laminating of cell and biocompatible material has been introduced and this could make the conformity with the desired shape or pattern for producing human entire organs for transplantation. This special printing technique is known as "3D Bio-Printing", which has potential in biomedical application including patient-customized organ out-put. In this paper, we describe the current 3D bio-printing technology, and bio-materials used in it and present it's practical applications.

3차원 레이저 스캐너를 이용한 인쇄롤 가공에 관한 연구 (Study on Printing Roll Manufacturing by using 3 Dimensional Laser Scanner)

  • 강희신;노지환;손현기
    • 한국레이저가공학회지
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    • 제16권4호
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    • pp.17-23
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    • 2013
  • The research for the development of roll-to-roll printing process is actively underway on behalf of the existing semiconductor process. The roll-to-roll printing system can make the electronic devices to low-cost mass production. This study is performed for developing the manufacturing technology of the printing roll used in the printing process of electronic devices. The indirect laser engraving technology is used to create printable roll and the printable roll is made out of the chrome coated roll after coating copper and polymer on the surface of steel roll, ablating the polymer on the surface of roll and etching the roll. The 3 dimensional laser scanner and roll rotating systems are constructed and the system control program is developed. We have used the fiber laser of 100 W grade, the 3 dimensional laser scanner and the 3 axes moving stage system with a rotating axis. We have found the optimal conditions by performing the laser patterning experiments and can make the minimum line width of $24{\mu}m$ by using the developed 3 dimensional laser scanner system.

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