• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2013년도 춘계학술발표대회
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• pp.232-235
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• 2013

간 질환 진단을 위한 의료 초음파 동영상에서 호흡으로 인한 영상의 흔들림 현상은 전이시간(transit time) 요소와 같은 진단 파라미터의 신뢰도를 저하시킬 뿐만 아니라, 정확한 병변 형태의 추출을 어렵게 한다. 본 연구에서는 호흡 주기를 자동으로 감지하고 이를 기반으로 ROI 를 추적하는 방법과 프레임 샘플링을 통하여 TIC(Time-Intensity Curve) 형태의 왜곡을 보정하는 방법을 고찰한다. 세부적으로 동적 가중치와 모멘텀 요소를 고려한 추적 기법을 제시하고 유용성을 평가한다. 또한 호흡주기와 프레임간 유사도(similarity)를 기반으로 한 영상 샘플링 기법을 제안하고 이로부터 신호의 왜곡을 보정할 수 있음을 보인다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2013년도 추계학술발표대회
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• pp.1386-1389
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• 2013

조영증강 초음파 동영상은 측정 부위의 혈류의 형태와 특성 정보를 포함하지만, 이를 육안으로 판별하는 것은 매우 어려운 일이다. 이에 본 연구에서는 초음파 영상으로부터 간 질환과 연관한 병변을 추출하고 그 특성을 분석하기 위한 기반 기술로서 영상 처리 및 분석 기법을 제안한다. 마이크로버블(microbubble) 형태의 노이즈와 빠른 속도로 변화하는 각 프레임의 영상으로부터 근사화된 원형 또는 타원 형태로 나타나는 병변을 추출하기 위하여 허프 변환(Hough transform)을 이용한 병변 추출 기법을 제시하며, 추출한 병변의 특성을 분석하기 위하여 TIC(time intensity curve)의 특성과 조영 효과의 전이 시간(transit time) 등의 정보를 영상의 형태로 가시화하는 방법과 MRF(Markov random field) 모델을 이용한 영상개선 기법을 소개한다. 제안된 이론은 실제 간 질환 진단 초음파 영상에 적용하여 그 유용성을 평가한다.

• Medical Lasers
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• 제10권1호
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• pp.15-21
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• 2021

As technology advances at a rapid rate, innovations in regenerative medicine will eventually include the use of energy-based therapeutics, such as low intensity-pulsed ultrasound stimulation (LIPUs), pulsed electromagnetic field stimulation (PMFs), and low-level laser/light therapy (LLLt) or photobiomodulation therapy (PBMt). Among these treatments, LLLt/PBMt attracted significant attention by the turn of the century, as evidenced by the numerous publications compared to LIPUs and PMFs, particularly for augmented bone regeneration (ABR). This is a testament of how the maturation of technology and scientific knowledge leads to latent compounded applications, even when the value of a technique is reliant on empirical data. This article reviews some of the notable investigations using LLLt/PBMt for bone regeneration published in the past decade, focusing on how this type of therapy has been utilized together with the existing regenerative medicine landscape.

• 대한화상학회지
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• 제23권2호
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• pp.64-67
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• 2020

High-intensity focused ultrasound (HIFU) has been regarded as a non-invasive uterine-preserving treatment for women with uterine myoma. Numerous studies have reported that it is a relatively safe and effective treatment for uterine myoma. However, severe complications, such as deep thermal burn injuries, bowel perforation, and bladder injury, were reported on rare occasions. We report a case of a 4th degree burn on the lower abdomen after HIFU treatment for uterine myoma. Physicians must consider the possibility of deep thermal burn injuries when managing uterine myoma with HIFU.

• 전자공학회논문지SC
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• 제43권3호
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• pp.67-77
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• 2006

본 논문에서는 웨이브렛 변환과 SVM 분류기를 이용하여 3차원 초음파 볼륨으로부터 전립선 객체를 추출하는 방법을 제안한다. 제안한 방법에서는 웨이브렛 변환의 수평 수직 방향의 상세 영상들의 평균치들로부터 웨이브렛 변환 모듈러스 영상을 구함으로써 잡음전력 대비 전립선 윤곽에 대한 국부 최대치들의 첨예도가 큰 모듈러스 영상을 얻을 수 있다. 또한 전립선의 밝기 변이 특성 및 전립선 내외부의 질감 차이 등을 특징으로 한 SVM 분류기를 이용함으로써 전립선 윤곽 추출의 정확도를 크게 향상시킬 수 있다. 실험 결과, 제안한 방법을 이용하여 전립선 윤곽을 찾을 경우 전문가에 의하여 추출된 윤곽과 비교하여 절대 평균 거리가 1.89로 나타났다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8625-8628
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• 2016

Background: Central lymph node metastasis(CLNM) is common in papillary thyroid microcarcinoma (PTMC). The aim of this study was to define the pathohistologic risk grading based on surgical outcomes. Materials and Methods: Statistical analysis was performed to figure out the optimal cut-off values of size in preoperative ultrasound images for defining the risk of CLNM in papillary thyroid microcarcinoma. Receiver operating characteristic curves (ROC) studies were carried out to determine the cutoff value(s) for the predictor(s). All the patients were divided into two groups according to the above size and the clinic-pathological and immunohistochemical parameters were compared to determine the significance of findings. Results: The optimal cut-off value of tumor size to predict the risk of CLNM in papillary thyroid microcarcinoma was 0.575 cm (area under the curve 0.721) according to the ROC curves. Significant differences were observed on the multifocality, extrathyroidal extension and central lymph node metastasis between two groups which were divided according to the tumor size by the cutoff values. Patients in two groups showed different positive rate and intensity of Ki67. Conclusions: The size of PTMC in ultrasound images are helpful to predict the aggressiveness of the tumors, it could be an easy predictor for PTMC prognosis and assist us to choose treatment.

• 한국습지학회지
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• 제16권2호
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• pp.205-212
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• 2014

본 연구는 환경, 에너지, 재료 등 다양한 분야에 적용할 수 있는 초음파 기술을 수처리 공정에 적용하기 위한 기초 연구로 수행되었다. 초음파 기술과 같은 고도산화처리공법은 중금속, 내분비계장애물질, 의약물질 등의 미량오염물질 처리에 효과적이어서 하천, 호소, 습지의 수질 향상에 크게 기여할 수 있을 것으로 기대되고 있다. 초음파 기술은 파를 기반으로 하기 때문에 본 연구에서는 적용 주파수의 파장을 이용하여 $0{\sim}4{\lambda}$ 구간의 수위를 $1/4{\lambda}$ 간격으로 나누어 동일한 유입에너지 조건에서 발생하는 열에너지 및 초음파 캐비테이션의 화학적 효과를 정량화 하였다. 실험 결과 낮은 수위 (적은 부피)의 에너지 밀도가 높은 조건보다 높은 수위 (큰 부피)의 에너지 밀도가 낮은 조건에서 열에너지 및 화학적 효과가 극대화되는 것을 확인하였다. 이러한 현상을 반응기 내부의 캐비테이션 활성도 시각화를 통해 알아본 결과, 높은 수위 (큰 부피) 조건에서는 에너지 밀도가 낮음에도 불구하고 반응기 전체적으로 높은 활성도를 얻을 수 있기 때문인 것으로 확인되었다. 따라서 본 연구결과를 이용하여 초음파 기술을 수처리 분야에 적용할 경우 반응성 및 에너지 효율 측면에서 적용 가능성을 보다 높일 수 있을 것으로 예상된다.

• 센서학회지
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• 제18권5호
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• pp.377-384
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• 2009

The ultrasonic hyperthermia for oncology has been developed and studied. The HIFU(high intensity focused ultrasound) is the most recent method to treat the tumor by using ultrasound. In this study, an insertion-type transducer for treating a prostate cancer, which can focus the ultrasonic beam mechanically and electrically, was designed and developed. The developed transducer was composed of three arrays, and each array has 32 elements. For the purpose of the mechanical focusing, both side arrays are slanted to the center array by $15^{\circ}$. With this structure, NFL(near field length) was set up as 30 mm. The PZT-4 and two matching layers were used, and the backing layer was excepted to prevent energy losses. The acoustic field analysis and the heating test were performed to evaluate the performance of developed transducer. The shape of an acoustic field, peak pressure, and acoustic pressure distribution were compared with numerical simulation. The NFL was 32 mm, the beam width was 5 mm, focal area was $40\;mm^2$, and peak pressure was 5.5 MPa. With heating by using developed transducer, the temperature increased up to $33^{\circ}C$ at focal zone. As a result of this study, the usefulness of suggested transducer for prostate cancer hyperthermia was confirmed by the acoustic field analysis and the heating test with TMM(tissue mimicking) phantom.

• Annals of Rehabilitation Medicine
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• 제42권6호
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• pp.846-853
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• 2018

Objective To compare the effects of low intensity ultrasound (LIUS), traditional exercise therapy (TET), low level laser therapy (LLLT) and TET on temporomandibular joint (TMJ) pain and trismus following recovery from head and neck cancer (HNC). Methods Sixty participants following, who had experienced HNC, were randomly allocated to three groups of 20 people each. Each group received different therapy. Group A received LIUS and TET; group B received LLLT and TET; while group C received TET. All 60 participants were evaluated under the visual analog scale (VAS), the University of Washington Quality of Life questionnaire (UW-QOL) and the Vernier caliper scale (VCS) at the beginning of the therapies and after 4 weeks. Results ANOVA test revealed significant improvements across all three groups with outcomes of p<0.05. The results of the UW-QOL questionnaire showed a significant difference between groups A, B and C in favor of group A (p<0.05). The VAS results showed a more improvement in group A as compared to group B (p<0.05), while there was no statistical difference between groups B and C (p>0.05). The VCS results showed more improvement for the individuals in group B as compared to those in group C (p<0.05), while there was minimal difference between groups A and B (p>0.05). Conclusion The LIUS and TET are more effective than LLLT and/or TET in reducing TMJ pain and trismus following HNC.

• Clinical Pain
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• 제20권2호
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• pp.135-140
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• 2021

MiraDry^®, a microwave thermolysis device, is comparably new non-surgical agent in the field of eradication of sweat glands for treating axillary hyperhidrosis and osmidrosis. So far, altered sensation, swelling, and compensatory sweating are widely known as adverse effects of MiraDry^®. Of the few reported MiraDry^®-induced neuropathy cases, median and ulnar neuropathies are common. Although, one case has described radial nerve and posterior cord damage with maximized stimulation intensity, musculocutaneous nerve damage induced by MiraDry^® has not been reported. Here, we report a case of a 30-year-old woman experiencing left hand weakness after receiving MiraDry^® at a local dermatology clinic. Left brachial plexopathy, mainly involving the median nerve and the musculocutaneous nerve with partial axonotmesis, was confirmed by electrodiagnostic studies. Ultrasound evaluation showed corresponding results. This is the first case report of the musculocutaneous neuropathy by MiraDry^®.