• Title/Summary/Keyword: UC&C

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Advanced Unified Communication Service System (차세대 통합 커뮤니케이션 서비스 제공 시스템)

  • Shin, Young-Mee;Bae, Hyun-Joo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.8B
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    • pp.962-970
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    • 2011
  • This paper describes an advanced unified communication system. The advanced unified communications mean a service that integrates basic communications such as call, SMS, email, and chatting with social networking service considered as a new communication channel, presenting a unified user interface. The advanced unified communication system is composed of advanced UC(Unified Communications) applications, open UC service platform, and UC back-end servers. The advanced UC applications consist of web-based application and smart phone application. The open UC service platform provides a variety of service components that enable the third party applications to access basic communications and social network services within an enterprise. The UC back-end servers provide server functionalities for call, SMS, email, and chatting.

Features and Outcomes of Children with Ulcerative Colitis who Undergo a Diagnostic Change: A Single-Center Experience

  • Ito, Natsuki;Takeuchi, Ichiro;Kyodo, Reiko;Hirano, Yuri;Sato, Takuro;Usami, Masaaki;Shimizu, Hirotaka;Shimizu, Toshiaki;Arai, Katsuhiro
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.4
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    • pp.357-365
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    • 2021
  • Purpose: A change in diagnosis from ulcerative colitis (UC) to Crohn's disease (CD) has been reported in pediatric inflammatory bowel disease; however, only a few clinical characteristics and predictors of this diagnostic change have been reported. We aimed to describe the clinical characteristics of patients with UC who underwent a change in diagnosis to CD and identify variables associated with the change. Methods: The medical records of pediatric patients with UC who were followed up at the National Center for Child Health and Development between 2006 and 2019 were retrospectively reviewed. Clinical data on disease phenotype, laboratory parameters, endoscopic findings, and treatment of patients whose diagnosis changed to CD (cCD) were compared to those of patients whose diagnosis remained UC (rUC). Results: Among the 111 patients initially diagnosed with UC, 11 (9.9%) patients were subsequently diagnosed with CD during follow-up. There was no significant difference between the cCD and rUC groups in terms of sex, age at initial diagnosis, and the extent and severity of disease at initial diagnosis. Albumin and hemoglobin levels were significantly lower in the cCD group than in the rUC group. The proportion of patients who required biologics was significantly higher in the cCD group than in the rUC group (p<0.05). Conclusion: Approximately 10% children initially diagnosed with UC were subsequently diagnosed with CD. Hypoalbuminemia and anemia at initial diagnosis and use of biologics could be predictors of this diagnostic change.

Effects of fission product doping on the structure, electronic structure, mechanical and thermodynamic properties of uranium monocarbide: A first-principles study

  • Ru-Ting Liang;Tao Bo;Wan-Qiu Yin;Chang-Ming Nie;Lei Zhang;Zhi-Fang Chai;Wei-Qun Shi
    • Nuclear Engineering and Technology
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    • v.55 no.7
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    • pp.2556-2566
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    • 2023
  • A first-principle approach within the framework of density functional theory was employed to study the effect of vacancy defects and fission products (FPs) doping on the mechanical, electronic, and thermodynamic properties of uranium monocarbide (UC). Firstly, the calculated vacancy formation energies confirm that the C vacancy is more stable than the U vacancy. The solution energies indicate that FPs prefer to occupying in U site rather than in C site. Zr, Mo, Th, and Pu atoms tend to directly replace U atom and dissolve into the UC lattice. Besides, the results of the mechanical properties show that U vacancy reduces the compressive and deformation resistance of UC while C vacancy has little effect. The doping of all FPs except He has a repairing effect on the mechanical properties of U1-xC. In addition, significant modifications are observed in the phonon dispersion curves and partial phonon density of states (PhDOS) of UC1-x, ZrxU1-xC, MoxU1-xC, and RhxU1-xC, including narrow frequency gaps and overlapping phonon modes, which increase the phonon scattering and lead to deterioration of thermal expansion coefficient (αV) and heat capacity (Cp) of UC predicted by the quasi harmonic approximation (QHA) method.

A Study on the Impact Fracture Behavior of Side Plate for G/T 35ton Class FRP Vessel (35톤급 FRP선박 외판자재의 충격파괴거동에 관한 연구)

  • Lee, Jin-Jeong
    • Journal of Korea Ship Safrty Technology Authority
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    • no.7 s.25
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    • pp.64-76
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    • 2008
  • This paper describes the failure mechanism and Charpy impact test of Fiber glass Reinforced Plastic composites which it was actually used for side plate of vessel. There are two examinations. The examination I, the specimens which it given temperature range $-25^{\circ}C$-$50^{\circ}C$ and with different initial notch length did impact test and then it compared impact energy(Uc) and impact fracture toughness(GIC). The examination II, the specimens which it putted into fresh water and sea water for scheduled hours did impact test and it compared impact energy(Uc) and impact fracture toughness(GIC). From examination I, it showed that impact energy(Uc) and impact fracture toughness(GIC) were peak at ambient temperature and decrease as temperature reduced. Fracture toughness(GIC) showed increase as initial notch length reduced. From examination II, impact energy(Uc) and impact fracture toughness(GIC) tended to increase which specimens putted in fresh water compared with sea water and maximum tolerance rate tend to decrease as permeation hours will be long.

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Intravenous Mesenchymal Stem Cell Administration Modulates Monocytes/Macrophages and Ameliorates Asthmatic Airway Inflammation in a Murine Asthma Model

  • Mo, Yosep;Kang, Sung-Yoon;Bang, Ji-Young;Kim, Yujin;Jeong, Jiung;Jeong, Eui-Man;Kim, Hye Young;Cho, Sang-Heon;Kang, Hye-Ryun
    • Molecules and Cells
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    • v.45 no.11
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    • pp.833-845
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    • 2022
  • Although asthma is a common chronic airway disease that responds well to anti-inflammatory agents, some patients with asthma are unresponsive to conventional treatment. Mesenchymal stem cells (MSCs) have therapeutic potential for the treatment of inflammatory diseases owing to their immunomodulatory properties. However, the target cells of MSCs are not yet clearly known. This study aimed to determine the effect of human umbilical cord-derived MSCs (hUC-MSCs) on asthmatic lungs by modulating innate immune cells and effector T cells using a murine asthmatic model. Intravenously administered hUC-MSCs reduced airway resistance, mucus production, and inflammation in the murine asthma model. hUC-MSCs attenuated not only T helper (Th) 2 cells and Th17 cells but also augmented regulatory T cells (Tregs). As for innate lymphoid cells (ILC), hUC-MSCs effectively suppressed ILC2s by downregulating master regulators of ILC2s, such as Gata3 and Tcf7. Finally, regarding lung macrophages, hUC-MSCs reduced the total number of macrophages, particularly the proportion of the enhanced monocyte-derived macrophage population. In a closer examination of monocyte-derived macrophages, hUC-MSCs reduced the M2a and M2c populations. In conclusion, hUC-MSCs can be considered as a potential anti-asthmatic treatment given their therapeutic effect on the asthmatic airway inflammation in a murine asthma model by modulating innate immune cells, such as ILC2s, M2a, and M2c macrophages, as well as affecting Tregs and effector T cells.

The Design and Development of IEEE 802.11 Wireless MAC Protocol Emulation Using UC/OS System (UC/OS을 사용하여 IEEE 802.11 무선 맥 프로토콜 에뮬레이션의 설계 및 개발)

  • Wang, Jian;Park, Ji-Min;Chung, Joong-Soo
    • Proceedings of the Korea Contents Association Conference
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    • 2013.05a
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    • pp.245-246
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    • 2013
  • 본 논문에서는 UC/OS 시스템을 사용하는 IEEE802.11 무선 MAC프로토콜의 처리과정중탐색, 인증, 결합 과정을 이더넷으로 동작하는 하드웨어 위에 에뮬레이션하였다. 에뮬레이션 환경은ADSv1.2을 사용하고, RTOS는UC / OS를, 사용언어는 C언어를 활용하였다. 검증과정으로는 이더넷으로 구동되는AP와 단말 하드웨어에 각각PC를 하이퍼 터미널으로 접속하여 탐색, 인증, 결합과정에 해당하는 절차를 수행하였다.

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Effects of camptothecin on the expression of DNA topoisomerase I and c-myc in HL-60 human leukemia cells (HL-60 사람 백혈병 세포에서 camptothecin이 DNA topoisomerase l과 c-myc의 발현에 미치는 영향)

  • 정인철;정대성;류경자;박장수;조무연
    • Journal of Life Science
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    • v.10 no.6
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    • pp.621-629
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    • 2000
  • Camptothecin (CPT) is an antitumor alkaloid that has been isolated from the Chinese tree, Camptotheca acuminata. The cytotoxicity of CPT has been correlated to its inhibition of DNA topoisomerase (Topo) I by stabilizing drug-enzyme-DNA “cleavable complex" resulting in DNA single-strand breaks and DNA-protein crosslinks. This studies were designed to elucidate whether CPT regulates Topo I mediated by CPT in DNAs containing c-myc protooncogene. We have conducted experiments on Topo I purification, pUC-MYC I cloning and Topo I assay using electrophoresis, quantitative RT-PCR and Northern blotting techniques. CPT ingibited the relaxation activity of Topo I in pUC19 DNA at various concentrations (1-1000 $\mu$M), while it enhanced the cleavage of Topo I in the pUC-MYC I by forming a cleavable complex at relatively high concentrations (100-1000 $\mu$M). In HL-60 cells treated with CPT, the expression of c-myc gene was decreased over that in the control group with no changes in the expression of Topo I mRNA. Our results suggest that Topo I is the target of CPT cytotoxicity but it does not affect Topo I extression, and the suppression of c-myc mRNA expression by CPT is due to c-myc damage resulted from formation of a cleavable complex with CPT. CPT.

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A Study on the Estimation of In-situ Undrained Shear Strength Using Effective Stress Paths of Reconstituted Sample by Unconfined Compression Test (재구성 시료의 일축압축시험에서 유효응력경로를 이용한 원지반의 비배수 전단강도 추정에 관한 연구)

  • 박성재;오원택;정경환;여주태
    • Journal of the Korean Geotechnical Society
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    • v.19 no.1
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    • pp.93-102
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    • 2003
  • Unconfined compression test (UC) has been widely used to determine the undrained shear strength ($c_u$) of clay, because it is convenient and economical. However, UC can not represent the behaviour of in-situ stress condition and the strength obtained by the test is generally underestimated compared to that of triaxial compression, due to no confining pressure. Therefore, a simple and practical method to correct the ($c_u$) for sample disturbance and to be used in geotechnical practice is needed. This study is aimed at proposing the method to estimate in-situ undrained shear strength from UC with suction measurement. The proposed method is based on theoretical shear strength equation of perfect sample (Noorany & Seed, 1965), and effective overburden stress and analysis results ($A_f,\phi'$) of effective stress behaviour by UC are needed for the equation. The shear resistance angle ($\phi'$) can be simply estimated through the result that $K_f$-line slope of the UC is 1.6 times higher than that of triaxial compression test. The result of this study shows that the measured strength by this method is very similar to that of the undrained shear strength by triaxial compression test (CK$_0$UC).

Recycling of useful Materials from Fly Ash of Coal-fired Power Plant (석탄화력발전소에서 발생되는 비회로부터 유용성분의 회수)

  • Kim, Dul-Sun;Han, Gwang Su;Lee, Dong-Keun
    • Clean Technology
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    • v.25 no.3
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    • pp.179-188
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    • 2019
  • Upon the combustion of coal particles in a coal-fired power plant, fly ash (80%) and bottom ash (20%) are unavoidably produced. Most of the ashes are, however, just dumped onto a landfill site. When the landfill site that takes the fly ash and bottom ash is saturated, further operation of the coal-fired power plant might be discontinued unless a new alternative landfill site is prepared. In this study, wet flotation separation system (floating process) was employed in order to recover unburned carbon (UC), ceramic microsphere (CM) and cleaned ash (CA), all of which serving as useful components within fly ash. The average recovered fractions of UC, CM, and CA from fly ash were 92.10, 75.75, and 69.71, respectively, while the recovered fractions of UC were higher than those of CM and CA by 16% and 22%, respectively. The combustible component (CC) within the recovered UC possessed a weight percentage as high as 52.54wt%, whereas the burning heat of UC was estimated to be $4,232kcal\;kg^{-1}$. As more carbon-containing UC is recovered from fly ash, UC is expected to be used successfully as an industrial fuel. Owing to the effects of pH, more efficient chemical separations of CM and CA, rather than UC, were obtained. The average $SiO_2$ contents within the separated CM and CA had a value of 53.55wt% and 78.66wt%, respectively, which is indicative of their plausible future application as industrial materials in many fields.