• Korean Journal of Pharmacognosy
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• v.30 no.2
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• pp.99-104
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• 1999

During the screening for inhibitors of nitric oxide production in LPS-activated macrophage, RAW 264.7 cells. Five coumarins were isolated from chloroform extract of the root of Peucedanum japonicum. They were identified as praeruptorin A (1), xanthotoxin (2), psoralen (3), isopimpinellin (4), bergapten (5) on the basis of spectroscopic methods. The $IC_{50}$ values for nitrite production by activated macrophages were about $1.5\;{\mu}g/ml$ (1), $0.3\;{\mu}g/ml$ (2), $1.0\;{\mu}g/ml$ (3), $25\;{\mu}g/ml$ (4), $25\;{\mu}g/ml$ (5), respectively. However, the inducible nitric oxide synthase (iNOS) was not inhibited by treatment with these compounds. Their inhibitory effect on nitric oxide production was resulted from the supperssion of iNOS expression.

• Bulletin of the Korean Mathematical Society
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• v.37 no.2
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• pp.229-247
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• 2000

This paper is concerned with the impulsive Cauchy problem where the control function u is a possibly discontinuous vector-valued function with finite total variation. We assume that the vector fields f, $g_i$(i=1,…, m) are dependent on the time variable. The impulsive Cauchy problem is of the form x(t)=f(t,x) +$\SUMg_i(t,x)u_i(t)$, $t\in$[0,T], x(0)=$\in\; R^n$, where the vector fields f, $g_i$ : $\mathbb{R}\; \times\; \mathbb{R}\; \longrightarrow\; \mathbb(R)^n$ are measurable in t and Lipschitz continuous in x, If $g_i's$ satisfy a condition that $\SUM{\mid}g_i(t_2,x){\mid}{\leq}{\phi}$ $\forallt_1\; <\; t-2,x\; {\epsilon}\;\mathbb{R}^n$ for some increasing function $\phi$, then the imput-output function can be continuously extended to measurable functions of bounded variation.

• Korean Journal of Agricultural Science
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• v.2 no.1
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• pp.199-231
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• 1975

It is well known fact that antibiotic residues in milk of cows create significant problem for the fermented dairy industry and public health because of inhibition of starter activity and of creation of allergic disease. It can be assumed that antibiotic residues in milk of other aniimals also can create some problems for their infants as in the case of humen. For the above mentioned reasons, present studies were undertaken to determine concentration and duration of antibiotic residues in milk of cows, goats and dogs following intramuscular or intravenous injection and intramammary infusion of penicillin, streptomycin and oxytetracycline at usual dosage. The cylinder-plate method was used for their assay. The results obtained were summerized as follows: 1) Following the intramuscular injection of penicillin, the antibiotic was detected in milk of cows up to 72 hours, in milk of goats 48 hours and in milk of dogs 60 hours of postinjection. The mean peak concentrations were recorded at 12 hours as 0.136 I.U./ml in cows. 6 hours as 0.773 I.U./ml in goats and 3 hours as 1.192 I.U./ml in dogs. 2) Following the intramuscular injection of streptomycin, the antibiotic was detected in milk of cows and goats up to 36 hours and in milk of dogs 24 hours of post-injection. The mean peak concentration were recorded at 6 hours as $0.26{\mu}g/ml$ in cows and at 3 hours in goats and dogs $0.45{\mu}g/ml$ and $0.36{\mu}g/ml$ respectively. 3) Following the intra venous injection of oxytetracycline, the antibiotic was detectable in milk of all the test animals up to 48 hours of postinjection. The mean peak concentrations were recorded at 6 hours as $3.5{\mu}g/ml$ in cows $2.4{\mu}g/ml$ in goats and $2.0{\mu}g/ml$ in dogs respectively. 4) Following intrarnammary infusion of penicillin in amounts of 100,000 I.U. for cows, 20.000 I.U. for goats and 10,000 I.U. for dogs, the penicillin residues in milk of the infused quarter perssisted to 72 hours in cows and 84 hours in goats and dogs. 5) Following intramammary infusion of streptomycin in amount of 500mg for cows, 100mg for goats and 25mg for dogs, the streptomycin residues in milk of the infused quarter persisted to 72 hours in cows and goats and 60 hours in dogs. 6) Following intramammary infusion of oxytetracycline in amount of 500mg for cows, 100mg for goats and 25mg for dogs, the oxytetracycline residues in milk of the infused quarter persisted to 72 hours in cows and 60 hours in goats and dogs. 7) A corelation between the residual antibiotic concentration and milk yield in cows and goats was observed; That is, the lower in the milk production showed a higher the concentration of an antibiotic residues and a longer the time in persistance. 8) Intramammary transfer of the antibiotic from an infused to non infused quarters, in dogs, was observed following the intramammary infusion of penicillin. streptomycin and oxytetracyclne in amounts of 10.000 I.U. 25mg and 25mg respectively. However, no transfer by 100.000 I.U. or 20.000 I.U. of penicillin. 500mg of streptomycin and 100mg of oxytetracyline was observed in cows and goats. 9) In dogs, minimum dosage of antibiotics for transfer fro in treated to untreated quarters following intramammary infusion were 2,500 I.U. of penicillin and 5mg each of streptomycin and oxytetracycline.

• Journal of the Korean Mathematical Society
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• v.32 no.2
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• pp.329-339
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• 1995

Let us consider the Neumann problem for a quasilinear equation $$ (I_\varepsilon) {\varepsilon^m div($\mid$\nabla_u$\mid$^{m-2}\nabla_u) - u$\mid$u$\mid$^{m-2} + f(u) = 0 in \Omega {\frac{\partial\nu}{\partial u} = 0 on \partial\Omega. $$ where $1 < m < N, N \geq 2, \varepsilon > 0, \Omega$ is a smooth bounded domain in $R^n$ and $\nu$ is the unit outer normal vector to $\partial\Omega$.

• Transactions of the Korean Society of Mechanical Engineers
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• v.6 no.2
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• pp.107-112
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• 1982

In order to analyze and investigate in the fatigue behavior of the notched specimens under the two level stressing, the U-notched specimens of structural carbon steel which is generally used is prepared. The obtained results are summarized as follows; (1) The fatigue limit of the U-notched specimens is lower than that of the unnotched. The fatifue notch factor (.betha.) of the U-notched specimens is 1.44 for mild steel and 1.52 for harden steel. The notch sensitivity (q) is 0.68 for mild steel and o.8 for harden steel. That is, these facts show that harden steel is more sensitive to the notch than mild steel. (2) The fatigue life time of the U-notched specimens under the overstressing is shorter than under the constant stressing, and the degree of fatigue life time decrease is different to each stress level; the degree for the high stress level is more than for the low stress level. (3) The fatigue life time of the U-notched specimes under the understressing is longer than under the constant stressing, and the degree of fatigue life time increase for the low stress level is more than for the high stress level.

• Wind and Structures
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• v.29 no.1
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• pp.43-53
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• 2019

Vortex-induced vibration of three circular cylinders (each of diameter D) in an equilateral triangular arrangement is investigated using the immersed boundary method. The cylinders, with one placed upstream and the other two side-by-side downstream, are free to vibrate in the cross-flow direction. The cylinder center-to-center spacing L is adopted as L/D = 2.0. Other parameters include the Reynolds number Re = 100, mass ratio $m^*=2.0$, reduced velocity $U_r=2{\sim}15$ and damping ratio ${\zeta}=0$. Cylinder vibration responses are dependent on $U_r$ and classified into five regimes, i.e. Regime I ($U_r{\leq}3.2$), Regime II ($3.2<U_r{\leq}5.0$), Regime III ($5.0<U_r{\leq}6.4$), Regime IV ($6.4<U_r{\leq}9.2$) and Regime V ($U_r>9.2$). Different facets of vibration amplitude, hydrodynamic forces, wake patterns and displacement spectra are extracted and presented in detail for each regime.

• Phonetics and Speech Sciences
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• v.6 no.1
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• pp.3-10
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• 2014

This study investigated whether Korean vowels, /ɨ/ and /u/, are distinctively perceived after a labial consonant given the fact that native and Sino-Korean nouns showed only vowel /u/ after a labial consonant while this pattern was massively broken by the recent introduction of loanwords. For this purpose, a perception experiment was conducted with $V_1C_1V_2$ sequences in which different vowels /a, i, u/ and consonants /p, t, k/ occurred in $V_1$ and $C_1$ before the target $V_2$, /ɨ/ and /u/. The data was produced by six speakers each from two different age groups, Age20 and Age40/50 in the read speech style. The results showed that consonant /p/ attracted significantly more responses of /u/ from /VCɨ/ sequences and significantly less responses of /u/ from /VCu/ sequence than the other consonants did in both age groups. Furthermore, Age20 group showed significantly less percentage of /u/ responses than Age40 group when the preceding consonant was /p/ regardless of the target vowel. We suggest therefore that unlike the traditional belief of labial assimilation, there is neutralization after a labial consonant in which vowels /ɨ/ and /u/ are often realized as any sound between two vowels, /ɨ/ and /u/. That is, this vowel change is not categorial but it rather produces an ambiguous stimulus which attracts different responses from different listeners. Ambiguous stimulus was produced due to coarticulatory efforts in speech production and perceptual compensation. We also argue that there is generational difference such that Age40/50 group speakers showed stronger tendency to produce /u/ after a labial consonant regardless of whether the target vowel was /ɨ/ or /u/.

• Applied Biological Chemistry
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• v.38 no.1
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• pp.7-12
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• 1995

The purpose of this study was the development of promoter for the lacZ' gene. Two heterologous promoter I and II of lacZ' gene were isolated from chromosomal DNA Bam HI fragment of yeast. The size of the promoter I was estimated to be 2.5 kb and ${\beta}-galactosidase$ activity was 124.6 U/mg protein, and the size of the promoter II was 4.0 kb and its ${\beta}-galactosidase$ activity was 168.8 U/mg protein, respectively. The stability of the recombinant YEp plasmid in the transformant was from 52.7 to 67.4% at minimal medium. YIp plasmid was constructed from YEp plasmid, and expressed both in E. coli and yeast. The promoter I aid II iso-lated from yeast chromosomal DNA can be used for promoter of plasmid YEp and YIp.

• International Commerce and Information Review
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• v.12 no.1
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• pp.35-54
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• 2010

This article explored the bank's responsibilities in electronic payment system between Korea and U.S.A. In order to complete my research object, I used Article 4A of the U.C.C. and EFTA of 1978 and by Electronic Financial Transaction Act of Korea as a analytic instruments. I also adapted America's various regulations to regulate concerned parties(banks). The system of this article is going to display as fellows; First, I presented recent trend and legal stabilities of electronic payment in this article. Second, I focuses on the allocation of risk of loss caused by ambiguous term in payment orders that do not express the subjective intention of the senders. I also did analyze the solution procession of error occurring in course of send of payment order. Third, In any action which involves a customers's liability for an unauthorized electronic fund transfer, the burden of proof is upon the financial institution to show that the electronic fund transfer was authorized. Forth, Customers have to report the error and unauthorized electronic fund transfer after awaring of it. Then bank will be liable for such a unauthorized electronic fund transfer. But If customer's failure to report, the bank has exemptions. Lastly, In order to prevent or detect the unauthorized electronic fund transfer, bank will agree with custom to establish a commercially reasonable security procedure, while bank has duties to notify in order to decrease the loss resulted from unauthorized payment order in korea law.

• Bulletin of the Korean Mathematical Society
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• v.55 no.2
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• pp.625-631
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• 2018

Let R be a commutative ring with identity and let R[x] be the collection of polynomials with coefficients in R. There are a lot of multiplications in R[x] such that together with the usual addition, R[x] becomes a ring that contains R as a subring. These multiplications are from a class of functions ${\lambda}$ from ${\mathbb{N}}_0$ to ${\mathbb{N}}$. The trivial case when ${\lambda}(i)=1$ for all i gives the usual polynomial ring. Among nontrivial cases, there is an important one, namely, the case when ${\lambda}(i)=i!$ for all i. For this case, it gives the well-known Hurwitz polynomial ring $R_H[x]$. In this paper, we completely determine the Krull dimension of $R_H[x]$ when R is a $Pr{\ddot{u}}fer$ domain. Let R be a $Pr{\ddot{u}}fer$ domain. We show that dim $R_H[x]={\dim}\;R+1$ if R has characteristic zero and dim $R_H[x]={\dim}\;R$ otherwise.