생약학회지 (Korean Journal of Pharmacognosy)
- 제30권2호
- /
- Pages.99-104
- /
- 1999
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
갯기름나물의 쿠마린에 의한 RAW 264.7 세포주의 Nitric Oxide 생성 저해활성
Inhibition of Nitric Oxide Production by Coumarins from Peucedanum japonicum in LPS-Activated RAW 264.7 cells
- 최희철 (생명공학연구소 세포반응조절 R.U.) ;
- 노태철 (생명공학연구소 세포반응조절 R.U.) ;
-
김보연
(생명공학연구소 세포반응조절 R.U.) ;
- 고학룡 (생명공학연구소 세포반응조절 R.U.) ;
-
오원근
(생명공학연구소 세포반응조절 R.U.) ;
-
성창근
(충남대학교 식품공학과) ;
- 민태익 (생명공학연구소 세포반응조절 R.U.) ;
-
안종석
(생명공학연구소 세포반응조절 R.U.) ;
-
이현선
(생명공학연구소 세포반응조절 R.U.)
- Choi, Hee-Cheol (Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology) ;
- Rho, Tae-Cheol (Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology) ;
-
Kim, Bo-Yeon
(Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology) ;
- Ko, Hack-Ryong (Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology) ;
-
Oh, Won-Keun
(Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology) ;
-
Seong, Chang-Keun
(Department of Food Science and Technology, Chungnam National University) ;
- Mheen, Tae-Ick (Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology) ;
-
Ahn, Jong-Seog
(Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology) ;
-
Lee, Hyun-Sun
(Cellular Response Modifier R.U., Korea Research Institute of Bioscience and Biotechnology)
- 발행 : 1999.06.30
초록
During the screening for inhibitors of nitric oxide production in LPS-activated macrophage, RAW 264.7 cells. Five coumarins were isolated from chloroform extract of the root of Peucedanum japonicum. They were identified as praeruptorin A (1), xanthotoxin (2), psoralen (3), isopimpinellin (4), bergapten (5) on the basis of spectroscopic methods. The