• 대한유전성대사질환학회지
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• 제12권2호
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• pp.99-103
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• 2012

I형 타이로신혈증은 타이로신의 분해 과정 중 최종단계에 관여하는 효소인 fumarylacetoacetate hydrolase(FAH)의 결핍에 의한 대사 이상질환이다. 급성 I형 타이로신혈증은 치명적인 간부전이나 혈액응고장애와 같은 급성 임상증상이 나타난 이후에는 예후가 불량하였으나 최근에는 신생아 대사이상 선별검사를 통해 조기 진단이 가능해졌고 2-(2-nitro-4-trifluoro-methylbenzyol)-1,3 cyclohexanedione nitisinone (NTBC) 약물 치료로 타이로신혈증의 치료 성적이 향상됨에 따라 신생아 대사이사 선별검사를 통한 조기 진단과 조기 치료가 더욱 중요해졌다고 할 수 있다. 이에 저자들은 심각한 출혈이나 간부전과 같은 급성 이상 증상이 나타나기 전 신생아 대사이상 선별검사로 조기 진단 및 조기 중재적 치료로 양호한 경과를 보이고 있는 I형 타이로신혈증 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 한국의류학회지
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• 제18권2호
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• pp.211-220
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• 1994

The purpose of this study was to analyze the foot type by cluster analysis for footwear. The sample size for the study was 200 college womens between age 19 and 23 in Pusan urban area. There were measured 17 items of the foot for factor analysis and cluster analysis. The result was as follows : 1. 1'here were 9 items selected by factor analysis. 2.'rho cluster analysis of the foot must be analyzed by direct and indirect measurement indivisually. 3. The cluster analysis of the direct measurement ; Cluster 1 : 1'he foot length is all much the same to mean value of this age group and the items of width and circumference are relatively small to other clusters. Cluster 2 ; The foot length is relatively small to other clusters and the items of width and circumference are all much the same to mean value of this age group. Cluster 3 ; The foot sine Is relatively large to other clusters. 4. The cluster analysis of indirect measurement ; Cluster 1 ; The (cot print angle is high find Metatarso-Phalanx angle is transformed Cluster 2 ; The foot print angle is low and Melatarso-Phalanx angle is normal. Cluster 3 : Tho foot print angle Is middle and Metatarso-Phalanx angle is all the mush same to mean value of this age group. Cluster 4 . The foot print angle Is the most value and Metatarso-Phalanx angle is normal.

• 보존과학연구
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• 통권35호
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• pp.25-44
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• 2014

이 연구에서는 유물 전시관을 대상으로 Active type과 Passive type에 의한 VOCs의 측정 분석법을 사용하여 전시실 내 외의 연중, 계절별 농도를 조사하고 측정방법에 따른 농도 비교를 통해 측정방법 간의 상관성을 비교하였다. 그 결과, Active type에 의한 전시실 TVOC의 연중 평균 농도는 $906.5{\mu}g/m^3$으로 대부분 조사 기간 동안 환경부 기준을 1.8배 이상 초과하였다. Active type에 의한 전시실의 ${\Sigma}VOCs$ 농도는 Passive type 보다 높았다. 일부 VOCs는 시간의 경과에 따라 감소하나 일시적인 상승 경향을 나타내기도 했다. Active type에 의한 전시관의 연평균 I/O비는 TVOC 9.0, ${\Sigma}VOCs$는 34.0으로 조사되어 ${\Sigma}VOCs$가 전시실 내부에서 다량 발생하는 것을 확인하였다. 두 방법 간의 상관성 분석 결과, ${\Sigma}VOCs$의 상관계수는 0.367이었으며 톨루엔은 0.567로 두 분석 방법 간의 연관성이 가장 큰 것으로 조사되었다.

• 한국조경학회지
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• 제30권4호
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• pp.9-18
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• 2002

This study investigated the influential range of landmarks and the relationship between landmarks and cognition factor so as to offer basic data to be used for the effective use and the management of landmarks. In this study, eighteen famous landmark in Seoul were selected and analyzed. The result of this study can be summarized as follows : 1) First, eighteen determining elements of cognition factors were selected via documents survey. Second, general cognition factors of landmarks were analysed using these elements through questionnaires to specialists. As a result of factor analysis, historic cultural factor, scale factor, visual form factor, locational factor and uniqueness factor were revealed. 2) According to revealed cognition factor, eighteen landmarks are categorized into four types using MDS method via questionnaire to resident in Seoul city. These four types of landmarks are: type I that are recognized by historic cultural factor; type II that are recognized by scale factor; type III that are recognized by uniqueness factor; and type IV that are recognized by visual form factor. 3) As the result of regression, the influential range of landmarks were revealed at about a 10km radius(type I : 12km type II : whole area of Seoul city≒15km, typeIII : 8.7km, typeIV : 8.5km). 4) As a result of analysing the correlation between the influential range and the cognition factor through multiple linear regression analysis, the locational factor is the main factor affecting the influential range of landmarks in every type. The uniqueness factor comes next, which affects influential range partially. 5) Except type 1, as a result of analysing the correlation between influential range and the physical heights of landmarks, a quadratic equation is revealed, showing that the influential range of landmarks over 200 meters in height shows a radical change. Landmarks can be used as reinforcement tools of legibility, effective tools for landscape management and for the improvement of a community's image. This study on the influential range of landmarks and main cognition factor can be utilized as a landmark management plan and in urban planning, such as a new town plan.

• 복식문화연구
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• 제8권5호
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• pp.668-680
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• 2000

The study presents the general types and individual differences of the shape of the adult women's neck and shoulder in our country. It is based on the average value, the standard deviation, the maximum value, the standard deviation, the maximum value, the minimum value and c.v. measured from the women at the age of 19 through 64. The results of this study are as follows ; 1. The factors by factor analysis are five. The first is the size factors of the neck and shoulder. The second is shape factor of neck. The third is plane view and length factor of the neck. The fourth is the side view factor of the neck and shoulder. The fifth is the shape factor of shoulder. Therefore the shape of the neck and shoulder should be examined in the shape factors as well as in the size factors as well as in the size factors for the designing body-suitable clothes. 2. The factors of the concrete objects are the solid view of neck and shoulder, the cross-sectional view of neck line, side view of neck and shoulder and length of neck. The explainable measuring items for the factors are the difference of the length between lower neck round line and the 4㎝ above neck round line, the length of neck, the angle of inclination between fore neck and back neck, the angle of inclination of the side shoulder, the difference of the height between fore neck point and back neck point, the width of shoulder, the width of chest and the width of back. 3. The concrete objects of the neck and shoulder have five types ; Type Ⅰ is average type, Type Ⅱ is thick short neck and the drooping shoulder type, Type Ⅲ I is slender long neck and lean-back shoulder type, Type Ⅳ is thick and rising shoulder type and Type Ⅴ is slender and drooping shoulder type.

• International Journal of Precision Engineering and Manufacturing
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• 제1권1호
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• pp.5-14
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• 2000

In the design of epicyclic gearing, the analysis of interference and mechanical efficiency is an important index. As an applied way, epicyclic gearing can be used for planetary gear drive and differential gear unit. In case that one of its components is fixed with intend, it is called planetary gear drive. On the contrary, in case that no component is fixed, it is called differential gear unit. In this paper, various design constraints and interferences are defined for 2K-H I type epicyclic gearing which is a basic arrangement of diverse epicyclic gearings. And various interferences are analyzed, and mechanical efficiency is calculated in case that 2K-H I epicyclic gearing is used for a differential gear unit as the change of gear ratio, cutter pressure angle, addendum modification coefficient. As that results, trend of mechanical efficiency is investigated in the ranges of addendum modification coefficients which would not lead to interferences, and the optimal range of addendum modification coefficient which can generate the maximum mechanical efficiency are presented. In order to prove results of theoretical efficiency analysis, experimental studies are performed.

• 복식문화연구
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• 제28권5호
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• pp.639-651
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• 2020

This study utilized data to classify and characterize the body types of plus-size adult men aged in their 30s and 40s. Diversity is an important factor in the era of inclusive design, and discussion about size diversity to include the plus size should be accommodated. Data from 493 adult men classified as obese (with a World Health Organization criterion ≥25 BMI) were used for the analysis. The results of the study are as follows. Six independent factors were extracted using factor analysis for cluster analysis, which were then classified into five types. Type 1 (29.01%) was identified as body type I with the smallest degree of obesity. Type 2 (15.4%) was identified as body type Y with wide shoulders and a thin waist. Type 3 (14.2%) was the largest body volume (body type O), while the fourth (19.27%) identified as body type H has a large height and upper body. Lastly, type 5 (22.11%) has a long lower body and a slim abdomen, referred to as body type X. This study presents a basis for the development of various clothing sizes utilizing the body shape characteristics of plus-size men in their 30s and 40s. Follow-up research is needed to develop patterns for plus size men and to design various products.

• Journal of Chest Surgery
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• 제23권4호
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• pp.715-719
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• 1990

Thymoma is defined as a neoplasm of the epithelialreticular framework cells of the thymus. The treatment of choice and the prognosis for patients with thymoma are still controversial subjects due to lack of a uniform histological classification and standardized criteria for typing thymic tumors. Between June 1985 and May 1989, eight patients underwent thymomectomy at the Department of Thoracic and Cardiovascular Surgery, Korea University Medical Center. A clinical analysis was performed and the following result was obtained. In histologic cell type, epithelial type was 2 cases, lymphocytic type 3 cases, and mixed type was 3 cases. The clinical stage was classified by Masaoka’s classification that Stage I was 4 cases, Stage II; 2 cases, Stage III; 2 cases and Stage IV was none. Myasthenia Gravis was associated with thymoma in 5 patients. In 8 patients, thymomectomy were performed. Adjuvant radiotherapy was performed in one patient with Stage I due to suspicious tumor remnant and in Stage II, III patients routinely. Combined chemotherapy was performed in one patient with Stage III due to local recurrence. We concluded that the most important prognostic factor of thymoma is extent of tumor invasion. And the presence of Myasthenia Gravis is no more prognostic factor. Surgical resection of thymoma is treatment of choice, If local invasion or distant dissemination is present, postoperative radiotherapy and /or combined chemotherapy is recommended.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권3호
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• pp.211-220
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• 2007

Objective: In organotypic culture of immortalized human oral keratinocytes (IHOK), the change of the growth and differentiation was investigated according to the fibroblast type and the involvement of mitogen-activated protein (MAP) kinase. Materials & Methods: IHOK was cultured three dimensionally with gingival fibroblast (GF), dermal fibroblast (DF) and immortalized gingival fibroblast (IGF). We characterized biologic properties of three dimensionally reconstructed IHOK by histological, immunohistochemical, and Western blot analysis. We also investigated whether MAP kinase pathway was involved in epithelial-mesenchymal interaction by Western blot analysis. Results: The best condition of three dimensionally cultured IHOK was the dermal equivalent consisting of type I collagen and IGF. IGF increased the expression of more proliferating cell nuclear antigen (PCNA), involucrin than GF and DF in response to co-culture with IHOK. Extracellularly regulated kinase (ERK) pathway was activated in organotypic co-culture with IGF. Conclusion: The organotypic co-culture of IHOK with dermal equivalent consisting of type I collagen and IGF resulted in excellent morphologic and immunohistochemical characteristics and involved ERK pathway. The epithelial-mesenchymal interaction was activated according to the fibroblast type.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1988년도 가을 학술발표회 논문집
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• pp.18-23
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• 1988

This study on the elasto-plastic analysis of spherical shell by rigia element method is classified into two parts : (1) theoretical consideration on elasto-plastic analysis of spherical shell, (2) elastic and elasto-plastic analysis of spherical shell with the open stiff ring. In 1982, Y. Tsuboi proposed the new analytical method which is called the rigid element method, for analyzing the elasto-plastic behavior of wall-type precast concrete structures by applying the concepts of rigid bodies-sprins model (i．e., when structures reach their ultimate state of leading, they may be yield, collapsed ana crushed into pieces, and each part or piece of structures mar move like a rigid body.). In this paper, for improvement and expansion this rigid element method, it is proposed the adaptation equation of rectangular-shaped spherical element and rectangular-shaped spherical bending element developed by present authors, and the analytical procedure for the elastic and the elasto-plastic increment method of structures.