• Journal of Integrative Natural Science
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• v.9 no.3
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• pp.166-170
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• 2016

Collagen plays a vital role in the maintenance of structure and function of a human body. It has been widely applied in various fields including biomedical, cosmeceutical, food, pharmaceutical and tissue engineering. In the present study, the docking behaviour of type I collagen with 15 different ligands namely hydroxymethylfurfural, methylglyoxal, methylsyringate, O-methoxyacetophenone, 3-phenyllactic acid, 4-hydroxybenzoic acid, kojic acid, lumichrome, galangin, artoindonesianin F, caffeic acid, 4-coumaric acid, origanol A, thymoquinone and quercetin was evaluated along with their putative binding sites using Discovery Studio Version 3.1. Docking studies and binding free energy calculations revealed that origanol A has maximum interaction energy (-40.48 kcal/mol) and quercetin with the least interaction energy (-15.44 kcal/mol) as compared to the other investigated ligands. Three ligands which are galangin, methylsyringate and origanol A were shown to interact with Asp21 amino acid residue of chain B (type I collagen). Therefore, it is strongly suggested that the outcomes from the present study might provide new insight in understanding these 15 ligands as potential type I collagen modulators for the prevention of collagen associate disorders.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.4
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• pp.930-937
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• 2007

In this paper, we address a design problem and a case study of a K-stage inspection system, which is composed of K stages, each of which includes an inspection process and a rework process. Assuming the type I and II errors of inspectors and the re-inspection policy for items classified as good, we determine the smallest integer of K which can achieve a given target defective rate. If K does not exist, holding the current values of the type I, II errors, we search reversely a new vector, (the defective rate of an assembly line, the defective rate of a rework process), which can give the target defective rate. Our formulas and methodology based on our K-stage inspection system could be applied and extended to similar situations with slight modifications.

• Journal of fish pathology
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• v.23 no.3
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• pp.273-280
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• 2010

To determine whether rock bream Oplegnathus fasciatus can be protected from rock bream iridovirus (RBIV) infection by intramuscular injection of long double-stranded RNAs (dsRNAs), we compared protective effect of virus-specific dsRNAs corresponding to major capsid protein (MCP), ORF 084, ORF 086 genes, and virus non-specific green fluorescent protein (GFP) gene. Furthermore, to determine whether the non-specific type I interferon (IFN) response was associated with protective effect, we estimated the activation of type I IFN response in fish using expression level of IFN inducible Mx gene as a marker. As a result, mortality of fish injected with dsRNAs and challenged with RBIV was delayed for a few days when comparing with PBS injected control group. However, virus-specific dsRNA injected groups exhibited no significant differences in survival period when compared to the GFP dsRNA injected group. Semi-quantitative analysis indicated that the degree of antiviral response via type I IFN response is supposedly equal among dsRNA injected fish. These results suggest that type I IFN response rather than sequence-specific RNA interference might involve in the lengthened survival period of fish injected with virus-specific dsRNAs.

• The Journal of Advanced Prosthodontics
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• v.8 no.5
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• pp.354-362
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• 2016

PURPOSE. The trueness and precision of acquired images of intraoral digital scanners could be influenced by restoration type, preparation outline form, scanning technology and the application of power. The aim of this study is to perform the comparative evaluation of the 3-dimensional reproducibility of intraoral scanners (IOSs). MATERIALS AND METHODS. The phantom containing five prepared teeth was scanned by the reference scanner (Dental Wings) and 5 test IOSs (E4D dentist, Fastscan, iTero, Trios and Zfx Intrascan). The acquired images of the scanner groups were compared with the image from the reference scanner (trueness) and within each scanner groups (precision). Statistical analysis was performed using independent two-samples t-test and analysis of variance (${\alpha}=.05$). RESULTS. The average deviations of trueness and precision of Fastscan, iTero and Trios were significantly lower than the other scanners. According to the restoration type, significantly higher trueness was observed in crown and inlay than in bridge. However, no significant difference was observed among four sites of preparation outline form. If compared by the characteristics of IOS, high trueness was observed in the group adopting the active triangulation and using powder. However, there was no significant difference between the still image acquisition and video acquisition groups. CONCLUSION. Except for two intraoral scanners, Fastscan, iTero and Trios displayed comparable levels of trueness and precision values in tested phantom model. Difference in trueness was observed depending on the restoration type, the preparation outline form and characteristics of IOS, which should be taken into consideration when the intraoral scanning data are utilized.

• Korean Journal of Applied Biomechanics
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• v.23 no.4
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• pp.295-306
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• 2013

The purpose of this study was to provide high school male shot putters training methods of gliding and delivery motion through comparative analysis of kinematic characteristics. To accomplish this purpose, three dimensional motion analysis was performed for the subjects(PKC, KKH, YDL) who participated in high school male shot putter competition on 92nd (2011), 93rd (2013) National Sports Festival. The subjects were filmed by four Sony HXR-MC2000 video cameras with 60 fields/s. The three-dimensional kinematic data of the glide, conversion and delivery phase were obtained by Kwon3d 3.1 version. The data of the shoulder rotational angles and projection angles were calculated with Matlab R2009a. The following conclusions had been made. With the analysis of the gliding and stance length ratio, the gliding length was shorter at the TG than the SG with short-long technique but the gliding and stance length ratio was 46.8:53.2% respectively. The deviation of the shots trajectory from APSS(Athlete-plus-shot-system) revealed that the PKC showed similar to "n-a-b-c-I" of skilled S-shape type, KKH and YDL showed "n-a-d-f-I'" of unskilled type. Furthermore, they showed smaller radial distance from the central axis of the APSS and the shots were away from the linear trajectory. From this characteristics, The PKC who performed more TG than SG had shorter glide with S-shape of APSS(skilled type) showed the better record than others with technical skill. But KKH and YDL had bigger glide ratio with "n-a-d-f-I'" of unskilled type and improved their records with technical factor. The projection factor had an effect on the record directly. Because PKC maintained more lower glide and transition posture with momentum transfer through COG's rapid horizontal velocity respectively the subject possessed the characteristics of high horizontal and vertical velocity with large turning radius from shot putter to APSS.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.6
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• pp.1060-1068
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• 2002

Compound continuously variable transmission(CVT) mechanisms are proposed, which can offer a backward mode, a geared neutral, an underdrive mode and an overdrive mode. They are composed of a 2K-H I type differential gear unit, a V-belt type continuously variable unit(CVU), a few friction clutches and gears, and not required of a starting device as a torque converter. Compound CVT mechanisms developed here present two distinct operating modes which are a power circulation mode and a power split mode. The transition of two modes takes place at the particular CVU speed ratio. For these CVT mechanisms, performance analysis related to speed ratio, power ratio and efficiency are executed and proven by experimental studies.

• Journal of the Korean housing association
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• v.16 no.2
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• pp.19-25
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• 2005

This paper call attention to the characteristics of apartment unit plans as to the outdoor adjacency methods. My arguments will attempt to investigate spatial composition and each room sizes of the unit plans. So far, very little has been done in this direction. I will limits myself to study 573 plans which have been designed from 1996 till 2003. What emerges from this analysis is that these samples divided 3 types derived from the outdoor adjacency methods. Type 1 limits itself to 39 square meters unit plans. Type 2 was distributed from 49 square meters to 200 square meters with the exception of 100-110 square meters. And, type 3 ranges from 59 to 160 square meters. Therefore, it could be profitable each room's environmental condition (daylight, ventilation and etc) and diverse apartment building types to design in extent 49-160 square meters.

• Journal of the Korean Data and Information Science Society
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• v.22 no.3
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• pp.565-574
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• 2011

The exponenetiated distribution has been used in reliability and survival analysis especially when the data is censored. In this paper, we derive Bayesian estimation of shape parameter and reliability function in the exponenetiated half triangle distribution based on Type-I hybrid censored data. Here we consider conjugate prior and noninformative prior and obtained corresponding posterior distributions. As an illustration, the mean square errors of the estimates are computed. Comparisons are made between these estimators using Monte Carlo simulation study.

• Journal of the Korean Society of Costume
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• v.24
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• pp.235-251
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• 1995

The purpose of this study is to analyze the charateristics of foot according to foot type and analyze the change of foot shape by movements for the sake of making a comfort-able footwears. On the 6 foot type classified by F.I. and F. P. A, this study analyze the surface areas and circumference in the surface area development figure. There are selected eighteen college girls and four movements. The results are as followes : 1. In the 6 foot types classified by F.I. and F. P. A., the circumferences were differed sig-nificantly. 2. In the 6 foot types classified by F.I. and F. P. A., the surface areas were not differed siginificantly. 3. By movements, circumferences and surfaces were not significantly changed according foot type. 4. By movements, the circumference IV, V were changed variously. 5. By movements, surface area of toes, M.P. joint and ankle were changed variously.

• Journal of Korean Society for Quality Management
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• v.38 no.4
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• pp.480-490
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• 2010

In this paper, two estimation methods(least square estimation and maximum likelihood estimation) were compared for Weibull distribution and Type I censoring. Data obtained by Monte Carlo simulation were analyzed using two estimation methods and analysis results were compared by MSE(Mean Squared Error). Comparison results show that maximum likelihood estimator is better for censored data and complete data with more than 30 samples and least square estimator is better for small size complete data(less than and equal to 20 samples).