• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9627-9630
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• 2014

Background: Although efficacy of aprepitant for suppressing emesis associated with single-dose cisplatin has been demonstrated, there are limited data on the antiemetic effect of this oral neurokinin-1 receptor antagonist during daily administration of cisplatin. Accordingly, we investigated the efficacy and safety of aprepitant in patients with head and neck cancer (HNC) receiving combination therapy with cisplatin and 5-FU (FP therapy). Materials and Methods: Twenty patients with HNC were prospectively studied who received a triple antiemetic regimen comprising granisetron ($40{\mu}g/kg$ on Days 1-4), dexamethasone (8 mg on Days 1-4), and aprepitant (125 mg on day 1 and 80mg on days 2-5) with FP therapy (cisplatin $20mg/m^2$ on days 1-4; 5-FU $400mg/m^2$ on days 1-5) (aprepitant group). We also retrospectively studied another 20 HNC patients who received the same regimen except for aprepitant (control group). Results: For efficacy endpoints based on nausea, the aprepitant group showed significantly better results, including a higher rate of complete response (no vomiting and no salvage therapy) for the acute phase (p=0.0342), although there was no marked difference between the two groups with regard to percentage of patients in whom vomiting was suppressed. There were no clinically relevant adverse reactions to aprepitant. Conclusions: This study suggested that a triple antiemetic regimen containing aprepitant is safe and effective for HNC patients receiving daily cisplatin therapy.

• Journal of the Korean Solar Energy Society
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• v.31 no.3
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• pp.109-115
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• 2011

It can gain both the electric energy production and disperse of light at the same time if DSSC is applied in the building as window system. It means to help facade design and to be used in lighting, heating, cooling energy directly by applicating DSSC BIPV window that is possible to daylighting and materialization of color. For this, optical characteristics analysis that is basic step must take precedence. So, basic databases of DSSC are builded and optical performances according to the double and triple glazing are evaluated by analyzing spectral data of various colored DSSC. As a result, Green(4) has the highest visible transmittance that is 28.8%, and Blue(3) has the lowest that is 0.3%. And, in case of optical performance of Green(4) depending on the incidence angle, SHGC and Tsol are decreased sharply from more than $60^{\circ}C$. Finally, It is judged that Red(4), Green(1), (4), Blue(4) are suitable for application in office building because visible transmittance is high and solar heat gain coefficient is low relatively in spite of composing to double and triple glazing.

• Journal of Korean Society of Transportation
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• v.20 no.5
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• pp.23-31
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• 2002

The headway of vehicles entering an intersection is closely related with the saturation flow rate and is a basic parameter required for determining the saturation headway and the start-up lost delay. Since such headway value reflects the drivers' behaviors and features of the intersection, all intersections don't have an equal value, but are affected by number and location of their lanes, changing types, local characteristics and time zone. Accordingly, this study attempted to suggest proper values on the basis of data by investigating headway in lanes. Number of exclusive through lanes was divided into single lane, double lanes and triple lanes, the locations of lanes were divided into inside lane, central lane and outside lane. As a result of investigating the headway, single through lane, double through lanes-inside lane, and triple through lane-outside lane showed as 1.73 sec., 1.71 sec. and 1.93sec., respectively. The result of calculating the area factor of business areas by fixing 1.00 for the residental area and applying relation between headway and saturation flow rate was 0.96. In the case of start-up lost delay lead dual left turn and directional separation were 1.41 sec. and 3.27 sec., respectively, showing the great difference. Therefore, different start-up lost delay according to changing type should be applied.

• KIEAE Journal
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• v.17 no.3
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• pp.15-21
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• 2017

Purpose: "Building energy design standard" is used to limit the thermal transmittance of building in Korea. However, it only covers the insulation standard for each appropriate elements of a building, not the thermal performance of Junction thermal bridge of windows and doors installed in wall. Therefore in this study, we have evaluated the thermal performance of Junction thermal bridge depending on installation method and position of windows and provide it as design data. Method: We analyzed heat transfer of 4-Track sliding window and tilt & turn triple glazed window that are placed in the first class category on window energy efficiency rating using Window 7.4 and Therm 7.4. Result : First, linear thermal transmittance of 4-Track sliding window differs by 2.2 times or more depending of installation method and location. It is higher than the linear thermal transmittance, 0.01W/mK, proposed by Passivhaus. Second, linear thermal transmittance of Tilt & turn triple glazed window differs by 7.7 times or more depending of installation method and location. The average linear thermal transmittance was less than 0.01W /mK when windows were installed on the internal wall insulation by the fixed hardware attachment method. Third, the thermal losses of a window caused by a junction thermal bridge are inversely proportional to the window area and converge gradually as the area increased.

• Environmental and Resource Economics Review
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• v.13 no.3
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• pp.387-415
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• 2004

This paper is intended to valuate air quality of the Seoul Metropolitan Area using triple-bound dichotomous choice (TBDC) contingent valuation method (CVM), supplemented by open-ended (OE) questionnaires. In the OE questionnaires, some respondents would state their willingness to pay (WTP) outside the limits of the WTP interval. It implies that WTP estimates based on the customary dichotomous choice (DC) questionnaires can be biased. We argue that the TBDC-CVM refined with OE questions is more efficient, because the latter helps purge the former of corrupted data that may have been collected by the TBDC interview process.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.1 no.1
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• pp.19-30
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• 1968

An experiment on the culture of laver, Porphyra tenera, was carried out from September 26, 1965 to February 12, 1966 at a laver farm on the coast of Gae-do, Hwacheong-myeon, Yeocheon-gun, Jeonranam-do, using 'Sae-ol-bal' (triple-knotted blind) laver bed, resulting in the following data: 1. 'Sae-ol-bal' laver, bed was less destroyed compared to ordinary (dual knotted blind) laver bed, the destruction rate being $9.8\%$ in 'Sae-ol-bal' laver bed, while $35.3\%$ in ordinary laver bed (Table 5). 2. The quantity of laver yield is the greatest on the edge-part, the next on the basal part, and the smallest on the middle part of the 'Sae-ol-bal' laver bed (Table 6, Figs. $7\~8$). 3. The ordinary laver bed may yield better harvest on the calm farm but 'Sae-ol-bal' laver bed yields better harvest at a farm where the destruction of bed is remarkable by wind and wave action.

• Journal of KIISE
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• v.42 no.7
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• pp.852-859
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• 2015

As the amount of knowledge information significantly increases, a lot of progress has been made in the studies focusing on how to reason large scale ontology effectively at the level of RDFS or OWL. These reasoning methods are divided into TBox classifications and ABox realizations. A TBox classification mainly deals with integrity and dependencies in schema, whereas an ABox realization mainly handles a variety of issues in instances. Therefore, the ABox realization is very important in practical applications. In this paper, we propose a realization method for analyzing the constraint of the specified class, so that the reasoning system automatically infers the classes to which instances belong. Unlike conventional methods that take advantage of the object oriented language based distributed file system, we propose a large scale ontology reasoning method using spark, which is a functional programming-based in-memory system. To verify the effectiveness of the proposed method, we used instances created from the Wine ontology by W3C(120 to 600 million triples). The proposed system processed the largest 600 million triples and generated 951 million triples in 51 minutes (696 K triple / sec) in our largest experiment.

• Journal of the Korea Convergence Society
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• v.9 no.11
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• pp.271-276
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• 2018

When the driver riding in a bicycle goes on board, the load of driver is shown differently according to the position loaded on the frame of bicycle. The load is applied most at the joint of bike frame and the load at the mid-part of frame is applied least than the other parts. So, the weight of frame is decreased as the part not applied with a lot of load is manufactured into the thin thickness. As the part applied with high load is manufactured into the thick thickness, it can be endured through this load. The configurations of general frame, double butted and triple butted were modelled by using CATIA program. The durabilities of each model due to the load of passenger were investigated by carrying the structural and fatigue analyses. As this study result investigated with the analysis program of ANSYS, the deformation of general frame happened most and that of triple butted became least. These simulation analysis data are intended to be used to design the actual bicycle frame in the most efficient way at design and manufacture.

• Restorative Dentistry and Endodontics
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• v.44 no.1
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• pp.10.1-10.11
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• 2019

Objectives: The objective of this study was to assess coronal discoloration induced by the following intracanal medicaments: calcium hydroxide (CH), a mixture of CH paste and chlorhexidine gel (CH/CHX), and triple antibiotic paste (3Mix). Materials and Methods: Seventy extracted single-canal teeth were selected. Access cavities were prepared and each canal was instrumented with a rotary ProTaper system. The specimens were randomly assigned to CH, CH/CHX, and 3Mix paste experimental groups (n = 20 each) or a control group (n = 10). Each experimental group was randomly divided into 2 subgroups (A and B). In subgroup A, medicaments were only applied to the root canals, while in subgroup B, the root canals were completely filled with medicaments and a cotton pellet dipped in medicament was also placed in the pulp chamber. Spectrophotometric readings were obtained from the mid-buccal surface of the tooth crowns immediately after placing the medicaments (T1) and at 1 week (T2), 1 month (T3), and 3 months (T4) after filling. The ${\Delta}E$ was then calculated. Data were analyzed using 2-way analysis of variance (ANOVA), 3-way ANOVA, and the $Scheff{\acute{e}}$ post hoc test. Results: The greatest color change (${\Delta}E$) was observed at 3 months (p < 0.0001) and in 3Mix subgroup B (p = 0.0057). No significant color change occurred in the CH (p = 0.7865) or CH/CHX (p = 0.1367) groups over time, but the 3Mix group showed a significant ${\Delta}E$ (p = 0.0164). Conclusion: Intracanal medicaments may induce tooth discoloration. Use of 3Mix must be short and it must be carefully applied only to the root canals; the access cavity should be thoroughly cleaned afterwards.

• Restorative Dentistry and Endodontics
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• v.44 no.2
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• pp.21.1-21.8
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• 2019

Objectives: The purpose of the present study was to evaluate the effect of calcium hydroxide with 2% chlorhexidine gel (HCX) or distilled water (HCA) compared to triple antibiotic paste (TAP) on push-out bond strength and the cement/dentin interface in canals sealed with White MTA Angelus (WMTA) or Biodentine (BD). Materials and Methods: A total of 70 extracted human lower premolars were endodontically prepared and randomly divided into 4 groups according to the intracanal medication, as follows: group 1, HCX; group 2, TAP; group 3, HCA; and group 4, control (without intracanal medication). After 7 days, the medications were removed and the cervical third of the specimens was sectioned into five 1-mm sections. The sections were then sealed with WMTA or BD as a reparative material. After 7 days in 100% humidity, a push-out bond strength test was performed. Elemental analysis was performed at the interface, using energy-dispersive spectroscopy. The data were statistically analyzed using analysis of variance and the Tukey test (p < 0.05). Results: BD presented a higher bond strength than WMTA (p < 0.05). BD or WMTA in canals treated with calcium hydroxide intracanal medications had the highest bond strength values, with a statistically significant difference compared to TAP in the WMTA group (p < 0.05). There were small amounts of phosphorus in samples exposed to triple antibiotic paste, regardless of the coronal sealing. Conclusions: The use of intracanal medications did not affect the bond strength of WMTA and BD, except when TAP was used with WMTA.