• Journal of Pharmaceutical Investigation
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• v.27 no.4
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• pp.303-311
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• 1997

Proliposomal patch of clenbuterol, ${\beta}_2-agonist$ bronchodilator, was prepared and its feasibility as a novel transdermal drug delivery system was examined. Proliposomal granules containing clenbuterol was prepared by a standard method using sorbitol and lecithin with (Rx 2) or without cholesterol (Rx 1). The porous structure of sorbitol in the proliposomes was maintained allowing tree flowability of the granules. Following contact with water, the granules were converted probably to liposomes almost completely within several minutes. It indicates that proliposomes may be hydrated, when they are applied on the skin under occlusive condition in vivo, by the sweat to form liposomes. Clenbuterol release from Rx 1 and Rx 2 proliposomes to pH 7.4 isotonic phospate buffer (PBS) across cellulose membrane (mol. wt. cut-off of 12000-14000) was retarded significantly compared with that from the mixture of clenbuterol powder and blank proliposomes. Interestingly, proliposomes prepared with lecithin and cholesterol (i.e., Rx 2 proliposomes) showed much more retarded release of clenbuterol than proliposomes prepared only with lecithin (i.e.. Rx 1 proliposomes), indicating that clenbuterol release from proliposomes can be controlled by the addition of cholesterol to the proliposomes. Proliposomal patches were prepared using PVC film as an occlusive backing sheet, two sides adhesive tape (urethane, 1.45 mm thickness) as a reservoir for proliposome granules and Millipore MF-membrane (0.45 mm pore size) as a drug release-controlling membrane. Rx 1 or Rx 2 proliposomes containing 4.6 mg of clenbuterol were loaded into the reservoir of the patch. Clenbuterol release from the patches to pH 7.4 PBS was determined using USP paddle (50 rpm)-over-disc release method. Clenbuterol release from the proliposomal patches was much more retarded even than from a matrix type clenbuterol patch (Boehringer Ingelheim ltd). Being consistent with clenbuterol release from the proliposomal granules, the release from the patches was highly dependent on the presence of cholesterol in the proliposomes : Patches containing Rx 2 proliposomes showed several fold slower drug release than patches containing Rx 1 proliposomes. When the patch containing Rx 1 proliposomes was applied on to the back of a hair-removed rat, clenbuterol concentration in the rat blood was maintained during 6-72 hrs. Transdermal absorption of clenbuterol from the patch was accelerated when the patch was prehydrated with 50 ml of pH 7.4 PBS before topical application. Above results indicate that sustained transdermal delivery of clenbuterol is feasible using proliposomal patches if the cholesterol content and pore size of the release rate-controlling membrane of patches, for example, are appropriately controlled.

• Journal of Bio-Environment Control
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• v.6 no.4
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• pp.235-241
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• 1997

This study was performed to investigate the behaviour of root zone environments under the control of soil temperature and tension of soil moisture near the root Bone of 'Kyoho' grapes tree grown on restricted root zone system in plastic greenhouse. Maximum diurnal air temperature inside plastic greenhouse ranged between 25.1 and 32.7$^{\circ}C$, and the average of nocturnal air temperature inside plastic greenhouse maintained at 18$^{\circ}C$ in winter season. Also the minimum diurnal relative humidity ranged between 50 and 55%, and the maximum nocturnal relative humidity ranged between 84 to 87%. At a depth of 15cm from soil surface, the average soil temperature maintained at 25.6$^{\circ}C$ for under-ground heating, and appeared to 17.4$^{\circ}C$ for unheated condition. Although the tension of soil moisture just after irrigation sharply decreased to pF 1.5, the tension of soil moisture at the depth of 15cm maintained at pF 2.0~2.2. It is suggested that the tension of soil moisture at the depth of 15cm might be used as the standard for the determination of irrigation set point. Effective drainage system is needed to prevent the spindly and succulent growth of vine trees grown in restricted root zone system.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.4
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• pp.18-27
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• 2012

This paper proposes a management method for a coastal black pine forest landscape considering the parallax effect. For the study, 10 coastal black pine forests in Gangneung were investigated about the average width of the coastal forests, the average diameters, and the intervals of the pines. Categorizations were realized for the 3 types of scene(sea, field, mountain, residential area, commercial area), diameter(16cm, 22cm, 28cm) and interval(5m, 7m, 10m) to produce a total of 45 scenic simulations. An investigation was made on the scenic preferences using 45 simulation images with S.D, and Likert Scales. The results were as follows: According the comparison of scenic preferences, natural landscapes(sea, field, and mountain) ranked high among preferences, with fabricated landscapes(residential area, commercial area) ranked low. The highest scenic preferences were shown with the seascape and an interval of 7m between the trees. On the contrary, the interrelationship was very low between the visual quantity of the scenic's elements(green, sky, building, road etc.) and the scenic preferences. As the results of the factor analysis, the 3 sense factors of "Depth(78.0%)" "Diversity(l5.6%)" and "Spatiality(6.4%)" explained coastal scenic preferences. "Spatiality" showed significant differences at intervals of 5~7m, and 10m between trees. This shows coastal forest management based on the interval of 10m standard affecting scenic preference.

• Journal of Korean Society of Forest Science
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• v.98 no.6
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• pp.633-638
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• 2009

This study was conducted to develop stem taper equations and stem volume tables for Eucalyptus pellita and Acacia mangium plantations in Kalimantan, Indonesia. To derive a most adequate taper equation for the plantations, three models - Max & Burkhart, Kozak, and Lee models - were applied and their fitness were statistically analyzed by using fitness index, bias, and standard error of bias. The result showed that there is no significant difference between the three models, but the fitness index was slightly higher in the Kozak model. Therefore, the Kozak model was chosen for generating stem taper equations and stem volume tables for the Eucalyptus pellita and Acacia mangium plantations. The resulted stem volume table was compared to the local volume table used in Kalimantan regions, but no significant difference was found in the stem volume estimation. It is expected that the results of this study would provide a good information about the tree growth in abroad plantations and support a reliable decision-making for their management.

• Journal of Korean Society of Forest Science
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• v.97 no.3
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• pp.274-284
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• 2008

For forest valuation, various input data were generally required: for example, slope, timber stocks, logging costs, hauling costs, market values of timber, afforestation costs, thinning costs, and so on. To enhance the efficiency of forest valuation process, it would be helpful to guide how and where to acquire such data sets. Moreover, to make an appraisal of timber assets through the Forestry Household Economy Survey, it would be inevitable to use standardized input data by region or tree species. Therefore, this research intended to develop a methodology of standardizing each input data, and to present its available data sources. Also, a guidance was presented to explain how to control input data within the appraisal process. Then, the appraisal process were analyzed and summarized in four types of information such as system flowchart, process flowcharts, detail flowcharts, and skimmer data, which are essential elements in developing an appraisal software, named EnVAST (Engine of Valuation System for Timber Assets). The software was designed to generate 'the standard forest valuation table' by species and province as the final output that is applicable for the forest valuation through the Forestry Household Economy Survey in Korea.

• Korean Journal of Environmental Agriculture
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• v.22 no.2
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• pp.130-136
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• 2003

An organophosphorus insecticide, chlorpyrifos and an arylnitrile fungicide, chlorothalonil commonly used far apple were subjected to a residual investigation under field conditions to ensure safety of terminal residues at harvest. After pesticides were applied at standard rate in apple tree fer 15 days for chlorpyrifos and 30 days far chlorothalonil, persistence of their residues in apple was investigated by several interval. At harvest, residual concentrations of chlorpyrifos and chlorothalonil in apple were 1.3 and 2.4mg/kg, respectively, and the residue levels were higher than MRL 1.0 mg/kg in Korea. As well fitted by the first-oder kinetics, biological half-lives of the pesticide residues in apple were 9.3 days for chlorpyrifos and 32.2 days for chlorothalonil. During the storage, half-lives of chlorpyrifos and chlorothalonil were 35.0 and 56.3days at room temperature, and 120.7 and 182.8 days at 412, respectively. Distribution of chlorpyrifos residue in flesh, fruit skin and stalk cavity of each apple corresponded to 0.1% 22.8% and 77.1%, respectively. In case of chlorothalonil, residue in flesh, fruit skin and stalk cavity was 4.4%, 10.4% and 85.2%, respectively.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.15 no.4
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• pp.119-132
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• 2012

The unmanaged abandoned concrete roads are vulnerable toward the issues on soil and water pollution, which requires flexible managing method such as eco-corridor after the process of ecological restoration. Among various alternations of abandoned concrete-paved roads, ecological restoration technique may be the most suitable method in sites including high quality of natural environment. Therefore, as in Young dong province, GyungBu express highway (227.24~229.04km), which is near to Hwang-gan IC, the survey to measure its effect of soil under the paving and water pollution by abandoned concrete roads was discussed. Then, the restoration method of plantings of landscape trees and hydro-seeding methods of artificial soil media was appraised through consecutive monitoring. The soil adequacy analysis shows lower percentage of heavy metal substance in each depth level compared to standard limit stated by the Ministry of Environment, along with low concerns raised after the analysis on heavy metal content of the spilled water on the concrete roads. Meanwhile, Korean Weigela (Weigela subsessilis L.H. Baily) was found to be withered in small-scale landscape trees planting sites. Among the seeding plants. the family of leguminosae, Silene armeria, Dendranthema boreale, Caryopteris incana and Aster yomena show good establishment results. Overall studies on planting of small and large landscape trees, planting method of container plants, planting method of ground cover plants, and germination and development trend of seeding plants of the experimental restoration site on abandoned concrete roads are revealing specific trends in the way landscape woody plants establishment and growth. Finally, this study suggests further studies and survey on varied plant restoration methods on abandoned concrete-roads for developed design guidelines of their methods.

• Korean Journal of Microbiology
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• v.52 no.1
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• pp.65-73
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• 2016

The aim of this study was to investigate the UV-resistance of radiation-resistant bacteria isolated from the water of Han River, South Korea. The water sample was irradiated with 3 kGy gamma radiation prior to isolation. Radiation-resistant bacterial strains were isolated by standard serial dilution method on R2A and 1/10 diluted R2A agar. The resulting purely isolated 60 cultures of bacteria were analysed for UV resistance and used in further studies. Based on the comparative analyses of 16S rRNA gene sequences, the bacterial isolates were divided into 3 phyla (4 genera): the phylum Deinococcus-Thermus (the genus Deinococcus) was 61.7%, Bacteroidetes (Hymenobacter and Spirosoma) was 23.4%, and Firmicutes (Exiguobacterium) was 15%. The results suggested that twenty-nine isolates are candidates new species belonging to Deinococcus, Hymenobacter, and Spirosoma, or other new genera. Nine bacterial strains were selected among the novel candidates and the UV-resistance analysis was conducted. All the candidate bacterial strains showed high UV resistance, similar to that of D. radiodurans R1.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.10a
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• pp.787-790
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• 2015

Recently, M2M (Machine to Machine) communication is possible the development of MTC (Machine Type Communication) devices becomes active. MCT devices in the form of home appliances have a low power consumption, low cost, short-range wireless communication in wireless home network. For purpose, MTC devices based on IEEE 802.15.4/Zigbee are composed in the form of cluster-tree topology, which consists of one PAN (Personal Area Network), one or other router and end of nodes. It happens that transmission delay, packet drop, and lacking data resulted from collision originated by a competition for allocating channels among MTC devices that greatly increased. At last performance of entire network can be degradated. This paper proposes that the beacon frame-based grouping algorithm using multiple channels in a MTC devices in the presence of wireless home network interference. The proposed algorithm decreases the transmission delay, dropped packet and throughput is more increase, so the proposal algorithm is more efficient than the IEEE 802.15.4/ Zigbee standard.

• Korean Journal of Environment and Ecology
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• v.23 no.3
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• pp.258-271
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• 2009

Various environmental parameters change and ecological succession often lead to decline of Pinus densiflora forest in Seoul. Due to decline of it, we proposed the ecological management for conserving and improving from decrease of its dominant area on there. We analysed the P. densiflora forest's classification and suggested its ecological management that based on relation to competition between dominant species in the upper tree layer, the presence of competitive species in shrub layer and vegetation management standard. The Pinus densiflora forest types has been classified 6 types by ecological characteristics. The results from categorized its types are following as; 1) Pinus densiflora pure forest type; edaphic climax Pinus densiflora forest(26.1%), Pinus densiflora pure forest(21.5%). 2) the forest of Pinus densiflora and other species that compete with each other type; Pinus densiflora-Quercus mongolica forest(28.0%), Pinus densiflora-Pinus rigida forest(13.1%), Pinus densiflora-Quercus acutissima(4.2%). We conclude that the results in these kind of 4 types; Pinus densiflora pure forest type where possible to maintain the forest by edaphic climax, human trampling damage, vegetation management(e.x. remove the competition species, shrub layers management etc.) are mainly need to negative management. Whereas, the others 4 types; Pinus densiflora and other species(Quercus variabilis, foreign species, naturalized species etc.) that compete with each other types are need to positive management such as manage the same niche competition species, shrub layers management, remove the foreign species, naturalized species etc.. In these kinds of ecological management are very necessary to maintain Pinus densiflora forest.