• Proceedings of the Korean Society of Medical Physics Conference
• /
• 2002.09a
• /
• pp.121-122
• /
• 2002

The main principle of radiation therapy is to deliver optimum dose to tumor to increase tumor cure probability while minimizing dose to critical normal structure to reduce complications. RTP system is required for proper dose plan in radiation therapy treatment. The main goal of this research is to develop dose model for photon, electron, and brachytherapy, and to display dose distribution on patient images with optimum process. The main items developed in this research includes: (l) user requirements and quality control; analysis of user requirement in RTP, networking between RTP and relevant equipment, quality control using phantom for clinical application (2) dose model in RTP; photon, electron, brachytherapy, modifying dose model (3) image processing and 3D visualization; 2D image processing, auto contouring, image reconstruction, 3D visualization (4) object modeling and graphic user interface; development of total software structure, step-by-step planning procedure, window design and user-interface. Our final product show strong capability for routine and advance RTP planning.

• Proceedings of the IEEK Conference
• /
• 2001.10a
• /
• pp.220-224
• /
• 2001

Waste tires are a significant problem with the increasing in number of automobiles. Therefore, many researches have been studied on this field. Recycling is the one of the popular method aspect to environmental and economical in the treatment methods of the waste tire, which loads that the reuse of scrap tire rubber has been a challenge in the past. However, it is not easy method to melt down and mold into new products because the in rubber is a cross-linked polymer. Most difficulty in recycling is the recycled product is not economic. Therefore, the goal of this study is to develop the high valuable products for reused waste tires. In this paper, we try to make an economic recycled technology using scrapped waste tires. This technology may applied for manufacturing the end products such as a rubber block and a ballast mat for high-speed train.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.5
• /
• pp.1877-1880
• /
• 2012

Breast cancer metastasis is the most common cause of cancer-related death in women. Thus, seeking targets of breast tumor cells is an attractive goal towards improving clinical treatment. The present study showed that CCL18 from tumor-associated macrophages could promote breast cancer metastasis via PITPNM3. In addition, we found that pachymic acid (PA) could dose-dependently inhibit migration and invasion of MDA-MB-231cells, with or without rCCL18 stimulation. Furthermore, evidence was obtained that PA could suppress the phosphorylation of PITPNM3 and the combination of CCL18 and PITPNM3. Therefore, we speculate that PA could inhibit breast cancer metastasis via PITPNM3.

• The Journal of the Korea Contents Association
• /
• v.16 no.3
• /
• pp.328-334
• /
• 2016

This research is studied the systemic production method of missing teeth and ridge lap type pontic for the maintenance and restoration of normal function of the surrounding tissue as the goal of prosthetic treatment. According to the dentists' opinions, with the illustrated design criteria that pontic has to be equipped, inflammation, periodontal disease, food residues, and self-cleaning effect are obtained a better result than the conventional production method. The pontic production method presented in this paper is considered good enough to be applied to a clinically.

• Korean Management Science Review
• /
• v.25 no.3
• /
• pp.87-99
• /
• 2008

Besieged by needs for upgrading the current Internet, social pressures, and regulatory concerns, a network operator may be left with few options to Improve his services. Yet he can still consider a transition prioritizing network services. In this paper, we describe a transition from a non-priority system to a prioritized one, using non-preemptive M/G/1 model. After reviewing the constraints and theoretical results from past research, we describe steps making the transition Pareto-improving, which boils down to a multi-goal search for a Pareto-improving state. We use a genetic algorithm that captures actual transition costs along with incentive-compatible and Pareto-Improving constraints. Simulation results demonstrate that the initial post-transition solutions are typically Pareto-improving. for non Pareto-improving solutions, the heuristic quickly generates Pareto-improving and incentive-compatible solutions.

• Journal of mucopolysaccharidosis and rare diseases
• /
• v.1 no.1
• /
• pp.15-18
• /
• 2015

Biopharmaceuticals, with their ability to treat many unmet needs, are seen as promising medications in diabetes mellitus, growth hormone deficiency, chronic renal failure, cancer, and rheumatoid arthritis. However, almost all biopharmaceuticals should be administrated by injection; IV, IM, and SC. In addition, these treatments are long term, and patients should receive frequent injections for many years. Patient compliance is therefore of critical importance to ensure treatment benefits. Therefore, the goal of drug product development should be focused on improving patient compliance by reducing injection-associated pain as well as stable formulation development. This review will suggest the kinds of factors that should be considered to minimize injection pain with regard to formulation, device, and injection procedures focused on SC injections.

• Journal of the Korean Professional Engineers Association
• /
• v.43 no.4
• /
• pp.44-49
• /
• 2010

Th Rach Gia Bypass Project, to be implemented under EDCF Loan VNM-12, constitutes a strategically important part of the Greater Mekong Sub-region Southern Coastal Corridor Project(the GMS-SCCP). The main goal of the GMS strategy is to promote sustainable economic growth, improve employment, and achieve poverty reduction by tapping the comparative advantages of Vietnam, Cambodia and Thailand. As a project manager who once took a responsible position for the completion of RGBP's detailed design, I would like to briefly introduce what our design team including the local sub-contractors had performed for the D/Design of this Project last year, especially in the field of highway, bridge and soft soil treatment method widely used in Mekong Delta area. With the performance of nearly two Projects due to the V.O. in one year on the prescribed time, it was a hard year but a rewarding one. To expand our horizon more about overseas projects, several recommendations for the brighter future of overseas projects are shown herein this paper.

• The Korean Journal of Pain
• /
• v.9 no.1
• /
• pp.232-234
• /
• 1996

For surgical Treatment of spastic deformities of the foot, selective peripheral neurotomies were introduced. These neurotomies utilize microsurgical techniques and intraoperative electrical stimulation for better identification of the function of the fascicles constituting the nerve. Selectivity is required to supress the excess of spasticity without excessive weakening of motor strength and without producing exaggerated amyotrophy. To achieve this goal, minimum one fourth of the motor fibers must be preserved. Neurotomies may be indicated when spasticity is localized to muscle or muscle groups supplied by a single or a few peripheral nerves that are easily accessible. To help the surgeon decide if neurotomy is appropriate, temporary local anesthetic block of the nerve with bupivacaine can be useful. Such a test can determine if articular limitations result from spasticity, musculotendinous contractures, or articular ankyloses because only spasticity is decreased by the test. In additon, these tests give the patient a chance to appreciate what to expect from the operation.

• Journal of Environmental Impact Assessment
• /
• v.14 no.5
• /
• pp.337-346
• /
• 2005

Pollution load allocation can likely be much controversial, which is essential to formulate the total water pollution load management plan. Existing rules(or guidances) in Korea, can provide no specific criteria for load allocation. Therefore, this paper studied(comprehensively) possible standards how or why to choose any particular allocation method, which was applied in the Gwangju City's load allocation for the satisfaction of set water quality goal. This load allocation is basically focused on the load reduction of domestic wastewater rather than industrial wastewater, because the land-use is strictly regulated and larger sources of pollution are few in the Gwangju City. This paper recommends the city to increase the capacity of sewage treatment plants, promote sewerage maintenance, and set higher effluent standards.

• The Korean Journal of Applied Statistics
• /
• v.16 no.1
• /
• pp.117-128
• /
• 2003

The goal of non-inferiority experiments is to show that the new treatment is not inferior to the standard experiment. In this paper we compare the three methods of variance estimation used in the unconditional exact tests of two proportions. The size and power of the tests with each variance estimation method are compared using complete enumeration.