• 한국정보통신학회논문지
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• 제21권9호
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• pp.1796-1807
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• 2017

국내 함정 추진체계는 기계식 추진체계에서 복합식 추진체계로 넘어가는 단계에 위치하고 있으며, 추진체계가 복잡해지면서 함정 추진체계의 제어 감시 기능을 하는 ECS의 기능이 중요해질 것으로 예상된다. 최근 국내에서 ECS(Engineering Control System) 개발의 국산화가 진행되면서 ECS 개발 과정에서 신뢰성 및 안정성에 대한 검증이 요구되고 있다. 제안하는 시뮬레이터는 HILS로 구성되었으며, 모의 목적에 따라 동력전달을 모의하는 축물리모델과, 장비제어를 모의하는 제어기모델, ECS와 통신하는 통신모델로 나누어진다. 본 논문에서는 복합식 추진체계인 CODLOG 체계에 대하여 ECS 검증용 시뮬레이터를 개발하고 시나리오를 설정하여 시뮬레이션을 수행하였다

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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• pp.309-314
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• 2006

In general DGPS system, the correction message is transferred to users by wireless modem. To cover wide area, many DGPS station should be needed. And DGPS users must have a wireless modem that is not necessary in standalone GPS. But SBAS users don't need a wireless modem to receive DGPS corrections because SBAS correction message is transmitted from the GEO satellite by L1 frequency band. SBAS signal is generated in the GUS(Geo Uplink Subsystem) and uplink to the GEO satellite. This uplink transmission process causes two problems that are not existed in GPS. The one is a time delay in the uplink signal. The other is an ionospheric problem on uplink signal, code delay and carrier phase advance. These two problems cause ranging error to user. Another critical ranging error factor is clock synchronization. SBAS reference clock must be synchronized with GPS clock for an accurate ranging service. The time delay can be removed by close loop control. We propose uplink ionospheric error correcting algorithm for C/A code and carrier. As a result, the ranging accuracy increased high. To synchronize SBAS reference clock with GPS clock, I reviewed synchronization algorithm. And I modified it because the algorithm didn't consider doppler that caused by satellites' dynamics. SBAS reference clock synchronized with GPS clock in high accuracy by modified algorithm. We think that this paper will contribute to basic research for constructing satellite based DGPS system.

• Journal of Veterinary Science
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• 제22권1호
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• pp.5.1-5.16
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• 2021

Background: Arctic-like (AL) lineages of rabies viruses (RABVs) remains endemic in some Arctic and Asia countries. However, their evolutionary dynamics are largely unappreciated. Objectives: We attempted to estimate the evolutionary history, geographic origin and spread of the Arctic-related RABVs. Methods: Full length or partial sequences of the N and G genes were used to infer the evolutionary aspects of AL RABVs by Bayesian evolutionary analysis. Results: The most recent common ancestor (tMRCA) of the current Arctic and AL RABVs emerged in the 1830s and evolved independently after diversification. Population demographic analysis indicated that the viruses experienced gradual growth followed by a sudden decrease in its population size from the mid-1980s to approximately 2000. Genetic flow patterns among the regions reveal a high geographic correlation in AL RABVs transmission. Discrete phylogeography suggests that the geographic origin of the AL RABVs was in east Russia in approximately the 1830s. The ancestral AL RABV then diversified and immigrated to the countries in Northeast Asia, while the viruses in South Asia were dispersed to the neighboring regions from India. The N and G genes of RABVs in both clades sustained high levels of purifying selection, and the positive selection sites were mainly found on the C-terminus of the G gene. Conclusions: The current AL RABVs circulating in South and North Asia evolved and dispersed independently.

• Nuclear Engineering and Technology
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• 제53권9호
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• pp.3026-3034
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• 2021

Multi-target X-ray tube is a new type X-ray source, and can be applied in many fields such as sensitive X-ray fluorescence analysis and medical imaging. In this work, we report an electric field modulation multi-target X-ray tube, which contains four targets (Cr, Ni, Au, Mo) coated on a Beryllium (Be) window. A four-valve electric field deflector was developed to deflect the electron beam to bombard the corresponding targets. Particle dynamics analysis software was employed to simulate the particle tracking of electron beam. The results show that the 30 keV electron beam could get a 6.7 mm displacement on the target plane by 10⁵ V/m electric field. The focus areas are about 2 mm × 5 mm and 4 mm × 2.5 mm after deflection in two directions. Thermal behavior calculated by ANSYS shows that the designed target assembly could withstand a 10 W continuous power. The optimum target thicknesses and emission spectra were obtained by Geant4 when the thickness of Be window was 300 mm and the electron beam incident angle was 0.141 rad. The results indicate that this multi-target X-ray tube could provide different X-ray sources effectively.

• Genomics & Informatics
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• 제19권1호
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• pp.11.1-11.8
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• 2021

For the novel coronavirus disease 2019 (COVID-19), predictive modeling, in the literature, uses broadly susceptible exposed infected recoverd (SEIR)/SIR, agent-based, curve-fitting models. Governments and legislative bodies rely on insights from prediction models to suggest new policies and to assess the effectiveness of enforced policies. Therefore, access to accurate outbreak prediction models is essential to obtain insights into the likely spread and consequences of infectious diseases. The objective of this study is to predict the future COVID-19 situation of Korea. Here, we employed 5 models for this analysis; SEIR, local linear regression (LLR), negative binomial (NB) regression, segment Poisson, deep-learning based long short-term memory models (LSTM) and tree based gradient boosting machine (GBM). After prediction, model performance comparison was evelauated using relative mean squared errors (RMSE) for two sets of train (January 20, 2020-December 31, 2020 and January 20, 2020-January 31, 2021) and testing data (January 1, 2021-February 28, 2021 and February 1, 2021-February 28, 2021) . Except for segmented Poisson model, the other models predicted a decline in the daily confirmed cases in the country for the coming future. RMSE values' comparison showed that LLR, GBM, SEIR, NB, and LSTM respectively, performed well in the forecasting of the pandemic situation of the country. A good understanding of the epidemic dynamics would greatly enhance the control and prevention of COVID-19 and other infectious diseases. Therefore, with increasing daily confirmed cases since this year, these results could help in the pandemic response by informing decisions about planning, resource allocation, and decision concerning social distancing policies.

• 한국콘텐츠학회논문지
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• 제22권1호
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• pp.1-9
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• 2022

본 연구의 목적은 SNS를 기반으로 향유되는 챌린지 콘텐츠를 게이미피케이션 개념과 MDA 프레임워크를 통해 통합적으로 고찰하는 것이다. 챌린지 콘텐츠는 생성 주체에 따른 범주화를 넘어 참여자가 콘텐츠의 생성과 향유를 주도하는 능동적인 모습을 보인다. 챌린지 콘텐츠를 분석한 결과, 메카닉스의 측면에서는 '상대적인 레벨', '표현 목적을 지닌 도전 과제', '파이디아적인 규칙'이 중점적으로 나타났다. 이는 '더 나은 표현을 위한 선택 및 경쟁', '이타심, 우월감'과 같은 내적 성취감을 발현하는 참여자의 다이내믹스로 연결되는 한편, 지속적으로 챌린지 콘텐츠에 참여할 수 있도록 하는데 기여한다. 에스테틱스의 측면에서는 참여자가 챌린지 콘텐츠를 통해 콘텐츠의 생성과 향유를 주도하는 놀이 문화의 주체로 기능하고 있음을 알 수 있다. 이런 현상은 정보 전달이나 상업적 광고 분야의 소임이었던 콘텐츠의 생성과 분배의 헤게모니를 역전시키는 결과를 가지고 왔다는데 의의가 있다.

• 한국항공우주학회지
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• 제50권2호
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• pp.111-118
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• 2022

전기-기계식 구동기(EMA)는 전기 모터와 기계적 동력전달 요소를 결합한 것으로 설계 자유도와 유지보수 측면에서 도심 항공 모빌리티(UAM)에 적합하다. 본 논문에서는 UAM의 로터 블레이드 피치각을 조종하는 EMA에 대한 연구 결과를 제시한다. 구동기는 역구동형 롤러 스크류를 기반하며, 2절 링크를 통하여 블레이드 피치각을 조종한다. 구동기만의 동역학과 이것을 포함한 블레이드 피치운동의 동역학 방정식을 유도하였다. 블레이드 피치 동역학 방정식의 경우 링크의 영향으로 등가 관성모멘트는 링크 각도에 따라 변한다. 넛트 운동의 관점과 블레이드 피치 운동의 관점에서 등가 관성모멘트의 변동을 분석·비교하는 과정을 제시하였다. 사례로 선정한 모델의 경우에 전자의 등가 관성모멘트 변동이 후자에 비하여 작았으며, 그래서 넛트 운동의 관점에서 유도한 모델이 제어기 설계에 적합하다고 판단한다.

• Applied Microscopy
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• 제51권
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• pp.20.1-20.12
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• 2021

We explored the link between mitochondrial biogenesis and mitochondrial morphology using transmission electron microscopy (TEM) in lymphoblasts of pediatric acute lymphoblastic leukemia (ALL) patients and compared these characteristics between tumors and control samples. Gene expression of mitochondrial biogenesis markers was analysed in 23 ALL patients and 18 controls and TEM for morphology analysis was done in 15 ALL patients and 9 healthy controls. The area occupied by mitochondria per cell and the cristae cross-sectional area was observed to be significantly higher in patients than in controls (p-value=0.0468 and p-value<0.0001, respectively). The mtDNA copy numbers, TFAM, POLG, and c-myc gene expression were significantly higher in ALL patients than controls (all p-values<0.01). Gene Expression of PGC-1α was higher in tumor samples. The analysis of the correlation between PGC-1α expression and morphology parameters i.e., both M/C ratio and cristae cross-sectional area revealed a positive trend (r=0.3, p=0.1). The increased area occupied by mitochondria and increased cristae area support the occurrence of cristae remodelling in ALL. These changes might reflect alterations in cristae dynamics to support the metabolic state of the cells by forming a more condensed network. Ultrastructural imaging can be useful for affirming changes occurring at a subcellular organellar level.

• 대한기계학회논문집B
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• 제34권1호
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• pp.77-82
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• 2010

소형분석시스템에서 미세채널의 상판이 제거되면 상판에 의한 빛 에너지 손실이 대폭 감소되어 광학측정법으로 대상을 분석할 때 장점을 갖는다. 본 연구에서는 상판이 없는 사각단면 미세채널 내 액체유동을 이해하려는 목적으로 실험과 전산유체역학 해석을 수행하였다. 개방형 사각단면 미세채널에서 입자추적기법으로 유속을 측정하였고, 채널의 단면적 변화에 따른 모세관 유동현상을 이론적으로 해석하였다. 단면의 너비와 높이가 각각 20 ${\mu}m$로 제작된 미세채널의 주입부에 물을 떨어뜨렸을 때 물은 오직 모세관 힘에 의해 미세채널을 따라 이동하였다. 액체의 젖음현상에 영향을 미치는 중요한 유동 파라미터는 채널의 크기와 표면장력, 점성 등으로 볼 수 있으며, 미세채널에서 액체 유동을 조절하는데 이용될 수 있다.

• 대한수의학회지
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• 제48권1호
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• pp.67-73
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• 2008

Porcine reproductive and respiratory syndrome (PRRS) is the most economically important viral infectious disease in pig populations worldwide. This study was conducted to better understand the epidemic and dynamics of PRRS virus (PRRSV) on each farm and to evaluate the risk of PRRSV infection in Korea. Interviews with pig farmers were carried out to obtain PRRS vaccination programmes in 60 pig farms throughout Korea. Blood samples were also collected from the 59 pig farms to investigate outbreak patterns of each farm. Vaccination against PRRS was performed in 16.7% farms for breeding pigs and 8.3% of farms for nursery pigs. According to the seroepidemiological analysis, 56 (94.9%) out of 59 farms were considered to be affected by PRRSV infection. The results revealed that 68.9% of sows tested were seroconverted and interestingly, gilt herds had the highest seropositive rate (73%), suggesting that gilts may play a key role in PRRSV transmission in sow herds. Among the PRRS-affected piglet herds, 33 (55.9%), 14 (23.7%) and 6 (10.2%) farms were initially infected with PRRSV during the weaning, suckling and nursery period, respectively. It seems likely, therefore, that PRRSV infection predominantly occurs around the weaning period in piglet herds. Based on antibody seroprevalence levels in both sow and piglet groups, we were able to classify patterns of PRRSV infection per farm unit into 4 categories; category 1 (stable sow groups and non-infected piglet groups), category 2 (unstable sow groups and non-infected piglet groups), category 3 (stable sow groups and infected piglet groups), and category 4 (unstable sow groups and infected piglet groups). Our data suggested that 43 (72.9%) farms were analysed to belong to category 4, which is considered to be at high-risk for PRRS outbreak. Taken together, our information from this study will provide insight into the establishment of an effective control strategy for PRRS on the field.