• Asian-Australasian Journal of Animal Sciences
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• 제19권9호
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• pp.1257-1261
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• 2006

Pleiomorphic adenoma gene-like1 (PLAGL1) encodes a zinc-finger (ZF) protein with seven ZFs of the C2H2-type which is a regulator of apoptosis and cell cycle arrest, and also regulates the secretion of insulin. In both human and mouse, PLAGL1 is a candidate gene for tumor suppressor and transient neonatal diabetes mellitus (TNDM). In this study, a 2,238 bp fragment covering the complete coding region was obtained and deposited to GenBank (accession number: DQ288899). The reverse transcriptase-polymerase chain reaction (RT-PCR) indicated that PLAGL1 was expressed almost equally in heart, liver, spleen, lung, kidney, stomach, small intestine, skeletal muscle, fat, uterus and ovary. Comparing the sequences of Large White and Meishan pigs, a C-T transition in exon 6 was found. The polymorphism could be detected by TaqI and was genotyped in five purebreds (Large White, Landrace, Meishan, Tongcheng and Bamei). Association analysis was performed between the polymorphism and carcass traits in 276 pigs of a "Large White${\times}$Meishan" F2 resource population. As a consequence, significant associations of the genotypes with shoulder backfat thickness (SFT) and internal fat rate (IFR) were observed. Pigs with TT genotype had low SFT and high IFR compared with TC or CC genotypes.

• 대한두경부종양학회지
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• 제20권1호
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• pp.24-28
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• 2004

Background and Objectives: Salivary gland tumors are relatively rare and constitute 3% to 4% of all head and neck neoplasms. Their relative infrequency, inconsistent classification, and highly variable biologic behavior make some difficulty, but some general features can be drawn regarding the incidence, pathology, and pattern of behavior of the various benign and malignant tumors of salivary glands. The present study aims to provide a clinical characteristics of salivary gland tumors. Materials and Methods: We analyzed retrospectively clinical features of the 138 patients who were treated surgically at Chonbuk National University Hospital from 1992 through 2002. Results: We found 107 benign and 31 malignant tumors. Among the patients, 58 were males and 80 were females. The most common age group was the fifties. The most common site of both benign and malignant was parotid gland in major salivary glands and palatal region in minor salivary glands. The most common presenting symptom was palpable mass in both benign and malignant tumor. Histopathologically, the most common type was pleomorphic adenoma in benign tumor and mucoepidermoid carcinoma in malignant tumor. All cases were treated surgically and the most common postoperative complications was transient facial nerve weakness. Conclusion: 138 cases of salivary gland tumors were presented with respect to their clinical features.

• 한국진공학회지
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• 제15권2호
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• pp.186-193
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• 2006

유기금속화학기상증착법으로 InGaAs/InGaAsP/InP 양자점 분자구조를 두 양자점 층간의 거리가 10 nm가 되도록 성장하여 성장된 구조에 대해 C-V, DLTS 및 PL 등의 전기 광학적 물성측정을 하였다. 그 결과 큰 양자점은 작은 양자점과 비교하여 장벽물질의 전도대역 가장자리로부터 먼 쪽에 에너지 준위가 형성되어 있음을 확인하였다. 큰 쪽 양자점에는 최소한 2개 이상의 에너지 준위에 운반자를 포획시킬 수 있음이 확인되었는데, -4 V의 역전압 하에서 측정된 양자점 분자구조의 에너지 준위는 장벽 가장자리로부터 0.35, 0.42, 0.45 eV 의 깊이에 각각 존재하였다. 인가된 전압의 변화에 대하여 약한 전기장 하에서는 양자점 분자구조의 에너지 준위들이 서로 결합되어 있다가 전기장이 증가하면서 이들 두 에너지 준위가 확연히 분리되는 모습을 확인할 수 있었다.

• International Journal of Industrial Entomology and Biomaterials
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• 제8권2호
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• pp.169-174
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• 2004

Bombyx mori nucleopolyhedrovirus(BmNPV) ecdysteroid UDP-glucosyltransferase gene (egt) promoter fragments of different lengths were amplified from BmNPV ZJ-8 genomic DNA by PCR. Reporter plasmids pBmegt542-luc, pBmegt309-luc and pBmegtl59-luc with luciferase (lue) driven by egt promoters were constructed. Both in vitro and in vivo expressions showed that BmNPV egt promoter activity requires the transactivation of viral factor(s), and expression of luc was detected earliest at 24 hrs post infection (pi). BmNPV ZJ-8 homologous region 3 (hr3) increased the expression of luc by over 1,600-fold. Molting hormone of 1.0 - 2.0 $\mu\textrm{g}$/$m\ell$ can dramatically down regulate expression of luc. Juvenile hormone analogue of 0.5-2.0 ${\mu}g$/$m\ell$ increased expression of luc by 145.8% to 75.7%. Deletion assay revealed that the promoter fragment of 159 bp contains the basal promoter structure; Promoter fragments of 309 bp and 542 bp showed similar but much higher transcriptional activities than that of 159 bp, suggesting that nucleotide from -159 to -309 nt upstream the translation initiation site harbors the main cis-acting elements.

• 한국전산유체공학회지
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• 제21권4호
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• pp.1-10
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• 2016

The analysis of characteristics of turbulent flow and thermal boundary layer for natural convection caused by fire along vertical wall is performed. The 4m-high vertical copper plate is heated and kept at a uniform surface temperature of $60^{\circ}C$ and the surrounding fluid (air) is kept at $16.5^{\circ}C$. The flow and temperature is solved by large eddy simulation(LES) of FDS code(Ver.6), in which the viscous-sublayer flow is calculated by Werner-Wengle wall function. The whole analyzed domain is assumed as turbulent region to apply wall function even through the laminar flow is transient to the turbulent flow between $10^9$<$Gr_z$<$10^{10}$ in experiments. The various grids from $7{\times}7{\times}128$ to $18{\times}18{\times}128$ are applied to investigate the sensitivity of wall function to $x^+$ value in LES simulation. The mean velocity and temperature profiles in the turbulent boundary layer are compared with experimental data by Tsuji & Nagano and the results from other LES simulation in which the viscous-sublayer flow is directly solved with many grids. The relationship between heat transfer rate($Nu_z$) and $Gr_zPr$ is investigated and calculated heat transfer rates are compared with theoretical equation and experimental data.

• 한국멀티미디어학회논문지
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• 제8권10호
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• pp.1322-1328
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• 2005

점성 유체를 담고 쳐는 실린더가 회전운동을 시작하면 회전 원판의 원심력과 에크만 펌핑 효과에 의해 실린더 외벽의 각운동량이 유체에 전달되는 과정에서 자오면상의 유동이 생기게 되고, 이 때 유체의 특성에 따라 유동장의 운동량 획득 특성이 다르게 나타나게 된다. 본 연구에서는 뉴턴 유체와 비-뉴턴 유체의 유동장 획득에 대한 정보를 가시화 영상에서 검출하고 이를 기반으로 유체의 특성을 분석하는 방법을 제안한다. 영상으로부터 운동량이 가장 크게 변화하는 전단면(shear front)의 위치를 알아내기 위해서, 유체의 운동량이 영상에서의 밝기정보로 나타나도록 실험환경을 구성한다. 입력 영상으로부터 유체의 운동량과 흐름을 가시화 할 수 있도록 가시화 매개 물질을 사용하여 영상을 획득하고, 영상에서 에크만 경계층의 전단면을 찾아내어 이동거리를 계산함으로써 유체의 특성을 분석하는 방안을 제시한다. 또한 유동장에 대해, LDV(Laser Doppler Velocimetry)로 측정한 값과 영상으로부터 얻은 값을 비교함으로써 제안된 방법에 대한 정확성을 검증하고, 검증된 데이터를 기반으로 비-뉴턴 유체와 뉴턴 유체에 대한 특성을 분석한다.

• Journal of Oral Medicine and Pain
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• 제38권4호
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• pp.325-331
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• 2013

보툴리눔 톡신은 신경독소로, 운동신경 말단부위에서 분비되는 아세틸콜린의 분비를 차단하여 근육의 위축을 유발하게 된다. 의학계 및 치의학계에서는 이를 이용하여 다양한 질환을 치료하는 것을 시도하고 있다. 치과영역에서는 저작근 수축, 심한 이갈이, 안면 틱, 구강안면 운동장애, 교근비대의 치료 등 과활성 근육성 질환을 치료하는 데 사용하고 있다. 악안면 영역에 보툴리눔 톡신을 주입하고 난 뒤 발생되고 있는 합병증으로는, 자연스럽지 못한 안면표정, 통증의 증가, 두통 등이 유발될 수 있다고 보고되고 있다. 본 증례에서는 교근부에 보툴리눔 톡신 주입 후 발생된 전방 개교합 증상에 대하여 보고하고자 한다.

• Corrosion Science and Technology
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• 제14권6호
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• pp.261-266
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• 2015

The capacity of passive metal to repassivate after film damage determines the development of local corrosion and the resistance to corrosion failures. In this work, the repassivation kinetics of 316L stainless steel (316L SS) was investigated in borate buffer solution (pH 9.1) using a novel abrading electrode technique. The repassivation kinetics was analyzed in terms of the current density flowing from freshly bare 316L SS surface as measured by a potentiostatic method. During the early phase of decay (t < 2 s), according to the Avrami kinetics-based film growth model, the transient current was separated into anodic dissolution ($i_{diss}$) and film formation ($i_{film}$) components and analyzed individually. The film reformation rate and thickness were compared according to applied potential. Anodic dissolution initially dominated the repassivation for a short time, and the amount of dissolution increased with increasing applied potential in the passive region. Film growth at higher potentials occurred more rapidly compared to at lower potentials. Increasing the applied potential from 0 $V_{SCE}$ to 0.8 $V_{SCE}$ resulted in a thicker passive film (0.12 to 0.52 nm). If the oxide monolayer covered the entire bare surface (${\theta}=1$), the electric field strength through the thin passive film reached $1.6{\times}10^7V/cm$.

• Journal of Radiation Protection and Research
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• 제11권1호
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• pp.77-82
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• 1986

Kerma와 흡수선량 사이의 관계를 결정하는 것은 선량측정의 기본적인 문제이다. 본 연구에서는 고에너지 치료용 선형가속기의 6MV X-선과 감마치료기의 $^{60}Co$에 대한 kerma와 흡수선량을 측정하였다. 본 실험결과는 $^{60}Co$감마선에 의한 물과 알루미늄의 과도 평형 영역에서의 흡수선량이 실제적으로 kerma와 일치하였으며, 최대선량 깊이는 6MV와 $^{60}Co$에서 각각 $1.45g/cm^2$과 $0.48g/cm^2$이었다. 최대 build-up에서의 흡수선량과 표면에서의 충돌 kerma의 비($K^{att}$)는 표준 조사면에서 물과 알루미늄에 대해, 6MV인 경우는 0.949, $^{60}Co$인 경우는 0.992이었다. 이 결과는 $K^{att}$의 물질에 대한 의존성이 매우 작음을 보여준다.

• 대기
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• 제18권1호
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• pp.55-70
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• 2008

The global time slice approach is a transient experiment using high resolution atmosphere-only model with boundary condition from the low resolution globally coupled ocean-atmosphere model. The present study employs this "time slice concept" using ECHAM4 atmosphere-only model at a horizontal resolution of T106 with the lower boundary forcing obtained from a lower-resolution (T42) greenhouse gas + aerosol forcing experiment performed using the ECHO-G/S (ECHAM4/HOPE-G) coupled model. In order to assess the impact of horizontal resolution on simulated East Asian summer monsoon climate, the differences in climate response between the time slice experiments of the present and that of IPCC SRES AR4 participating 21 models including coarser (T30) coupled model are compared. The higher resolution model from time slice experiment in the present climate show successful performance in simulating the northward migration and the location of the maximum rainfall during the rainy season over East Asia, although its rainfall amount was somewhat weak compared to the observation. Based on the present climate simulation, the possible change of East Asian summer monsoon rainfall in the future climate by the IPCC SRES A1B scenario, tends to be increased especially over the eastern part of Japan during July and September. The increase of the precipitation over this region seems to be related with the weakening of northwestern part of North Pacific High and the formation of anticyclonic flow over the south of Yangtze River in the future climate.