• Journal of the Korean Society of Safety
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• v.28 no.1
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• pp.125-131
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• 2013

When fire occurs in complex or building, toxic gas is important factor for evacuation because it cause death of evacuees. The effect of toxic gas which effects human motion is calculated using Purser's Fractional Effective Dose(FED). The FDS_EVAC is used for evacuation. However, FED of FDS_EVAC has some problem of application because it dose not considers evacuees's gender and age groups but using single subject. In this study, numerical analysis using modified FED which considers gender and age group of evacuees was performed. We investigate the effect of improved FED on the evacuation. We applied evacuation analysis to exhibition centre where the evacuees was set one thousand five hundred people. The FED is increasing with children 2%, male 17%, female 4%, adult 13% and elderly people 22%. Fatality is increasing due to increased FED.

• Journal of Korean Society on Water Environment
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• v.26 no.4
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• pp.557-565
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• 2010

Recently, regulations on toxic compounds in aquatic environment have been strengthened in korea due to the increasing public awareness of the water quality. Typically, these regulations include introduction of emerging toxic compounds and stricter effluent limitations for the already regulated compounds. However, too strict regulations may cause excessive burden on the industry. Therefore it is also important to assess the economic impacts when the new effluent limitation guidelines are introduced. The estimation of the additional cost for the wastewater dischargers to meet the new guidelines are based on the selected treatment technology to handle the hazardous substances and the regulatory levels for effluent limitations. To explore the procedures for cost estimation in enforcing new effluent limitations, a case study was performed specially for 1,4-dichlorobenzene. The pollutants of concern are surveyed for different industrial categories and various treatment technologies. For a given pollutant, the general performances of the treatment technologies are surveyed and a representative technology is selected. For a given technology, the capital cost and annual Operation and Maintenance (O&M) cost was calculated. The calculation of baseline costs to operate ordinary treatment technologies is also important. The ratio between the cost for introducing new treatment process and the baseline cost required for conventional technology was used to evaluate the economic impact on the industry. For 1,4-dichlorobenzene, steam stripping and activated carbon processes were selected as the specific treatment technologies. The cost effects to the regulation of the compound were found to be 6.4% and 14.5% increase in capital cost and O&M cost, respectively, at the flow rate over $2,000m^3/d$ for the categories of synthetic resin and other plastics manufacturing industry. For the case of petrochemical basic compounds manufacturing industry, the cost increases were 5.8% and 12.4%, respectively. It was suggested that cost effect analysis to evaluate the economic impacts of new effluent limitations on the industry is crucial to establish more balanced and reasonable effluent limitations to manage the industrial wastewater containing emerging toxic compounds in the wastewater.

• Fire Science and Engineering
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• v.20 no.2 s.62
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• pp.1-7
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• 2006

The aim of the research is to estimate the effect of smoke and combustion gases on humane body indirectly through measuring the toxicity of those. For this purpose, the toxic index of smoke and combustion gases was investigated by smoke hazard test and analysis of smoke which were conducted by KS F 2271 and NES 713 method respectively. It i s proved by KS F 2271 method that PASCON trough is suitable to the testing standard of interior material and construction of building. In addition, it is identified by NES 713 method that combustion gases occurring in PASCON product were only carbon dioxide and carbon monoxide, and the smoke index of those was 0.944. This value means that the hazard effect of smoke gases on humane ! body can possibly happens when exposed to the smoke gases for more than 30 min. In aspect of the domestic situation that have not regulated the hazard estimation and the emissions of smoke when the flame retarding ability of the products have been requested, the toxic indexes of PASCON products are comparatively low.

• Environmental Analysis Health and Toxicology
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• v.7 no.3_4
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• pp.17-35
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• 1992

In this study, it was examined the toxic effects of combination of buprofezin and carbaryl on hematological, biological and enzymetic parameters in rats. The administration of buprofezin or carbaryl both induced the tissue content of cytochrome P-450 and furthermore, the combination of the both increased significantly the liver content of cytochrome P-450 in rat. But cytochrome P-450 and NADPH -cytochrome c reductase activities in kidney were slightly increased. Administration of carbaryl and combination of the both also significantly increased hepatic aniline hydroxylase activity. In addition, in the combination group, glucose-6-phosphatase and lipid peroxidase activities were changed in the rat liver. Furthermore, cholinesterase was inhibited in rats treated with carbaryl or the combination of buprofezin and carbaryl. The above results suggested that the combined administration of buprofezin and carbaryl can induce more toxic effects than the single administration of buprofezin or carbaryl.

• Journal of Soil and Groundwater Environment
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• v.23 no.5
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• pp.37-44
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• 2018

Soil trace elements and their bioaccumulation in agricultural products have attracted widespread concerns, yet the crop uptake characteristics of trace elements in different soil-plants systems have been rarely investigated. Experiments were carried out to investigate the effect of soil properties on trace element concentrations in cabbage and radish. Soil pH and total organic matter were major factors influencing trace elements transfer from soil to vegetables. Inclusion of other soil properties in the stepwise regression analysis improved the regression models for predicting trace element concentrations. Consideration of other soil properties should be taken into account for more precise prediction of trace element concentrations in the two vegetables, which could help quantitatively evaluate the ecologic risk of toxic trace elements accumulation in crops.

• Journal of the Korean Institute of Gas
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• v.23 no.1
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• pp.54-61
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• 2019

As the market for portable electronic devices expands, the demand for Lithium Ion Battery (LIB) is also increasing. LIB has higher efficiency than other secondary batteries, but there is a risk of explosion / fire due to thermal runaway reaction. Especially, Electric Vehicles (EV) equipped with a large capacity LIB cell also has a danger due to a large amount of toxic gas generated by a fire. Therefore, it is necessary to analyze the risk of toxic gas generated by EV fire to minimize accident damage. In this study, the flow of toxic gas generated by EV fire was numerically analyzed using Computational Fluid Dynamic. Scenarios were established based on literature data and EV data to confirm the effect distance according to time and exposure standard. The purpose of this study is to analyze the risk of toxic gas caused by EV fire and to help minimize the loss of life and property caused by accidents.

• Environmental Analysis Health and Toxicology
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• v.8 no.1_2
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• pp.1-10
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• 1993

This study was done to determine the toxic effect of fthalide in rats which have oral administration at levels of 100 mg/kg/day for twelve days. It was examined the hematogram and serological parameters, and also the content of cytochrome P-450, the activity of NADPH-cytochrome c reductase, glucose-6-phosphatase, cholinesterase and carboxylesterase in liver. Any significant alteration of hematogram was not found but the value of AST, LDH and content of glucose in serum were statistically increased. The content of cytochrome P-450, the activty of NADPH-cytochrome c reductase were increased but glucose-6-phosphatase were slightly decreased compare with that of control group. The activity of cholinesterase was decreased slightly and on the contrary the activity of carboxylesterase was found to be the tendeny of increase in both of liver and serum.

• Environmental Analysis Health and Toxicology
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• v.30
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• pp.1.1-1.8
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• 2015

Objectives In this study, the effect of tube length and outer diameter (OD) size of hydroxylated-multi walled carbon nanotubes (OH-MWCNTs) on their uptake and toxicity was investigated in the nematode Caenorhabditis elegans using a functional mutant analysis. Methods The physicochemical properties of three different OH-MWCNTs were characterized. Uptake and toxicity were subsequently investigated on C. elegans exposed to MWCNTs with different ODs and tube lengths. Results The results of mutant analysis suggest that ingestion is the main route of MWCNTs uptake. We found that OH-MWCNTs with smaller ODs were more toxic than those with larger ODs, and OH-MWCNTs with shorter tube lengths were more toxic than longer counterparts to C. elegans. Conclusions Overall the results suggest the aspect ratio affects the toxicity of MWCNTs in C. elegans. Further thorough study on the relationship between physicochemical properties and toxicity needs to be conducted for more comprehensive understanding of the uptake and toxicity of MWCNTs.

• Journal of applied mathematics & informatics
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• v.27 no.1_2
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• pp.385-400
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• 2009

The adverse effect of harmful plankton on the marine ecosystem is a topic of deep concern. To investigate the role of such phytoplankton, a mathematical model containing distinct dynamical equations for toxic and non-toxic phytoplankton is analyzed. Stability analysis of the resulting three equation model is carried out. A continuous time variation in toxin liberation process is incorporated into the model and a stability analysis of the resulting delay model is performed. The distributed delay model is then extended to include the spatial distribution of plankton and the delay-diffusion model is analyzed with spatial and spatiotemporal kernels. Conditions for diffusion-driven instability in both the cases are derived and compared to explore the significance of these kernels. Numerical studies are performed to justify analytical findings.

• Journal of Environmental Science International
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• v.20 no.10
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• pp.1221-1232
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• 2011

We investigated the toxic effects of difenoconazole on the development in the African clawed frog, Xenopus laevis. To test the toxic effects, frog embryo teratogenesis assays using Xenopus were performed. Embryos were exposed to various concentrations of difenoconazole (0-30 ${\mu}M$). $LC_{100}$ for difenoconazole was 30 ${\mu}M$, and the $LC_{50}$ determined by probit analysis was 27.19 ${\mu}M$. Exposure to difenoconazole concentrations ${\geq}$5 ${\mu}M$ resulted in 10 different types of severe external malformation. Histological examinations revealed dysplasia of the eye, heart, liver, somatic muscle, and swelling of the pronephric ducts. The tissue-specific toxic effects were investigated with an animal cap assay. Blood cells were normally induced at a high frequency by mSCF and activin A. However, the induction of blood cells was strongly inhibited by the addition of difenoconazole. Electron micrographs of tested embryos showed the degeneration of somatic muscle and the shrinkage of microvilli on pronephric duct. The gene expression of cultivated animal cap explants was investigated by reverse transcriptase-polymerase chain reaction (RT-PCR). It revealed that the expression of the blood-specific marker(${\beta}$-globin II) and muscle-specific marker (XMA) were more strongly inhibited than the neural-specific marker(XEn2) by the addition of difenoconazole.