• Title/Summary/Keyword: Tool-chain

Search Result 386, Processing Time 0.029 seconds

Development of Supply Chain Management Simulator (SCM 시뮬레이터 개발)

  • Lim, Seok Jin;Mo, Chang-U
    • Proceedings of the Safety Management and Science Conference
    • /
    • 2013.04a
    • /
    • pp.355-365
    • /
    • 2013
  • Many manufacturing industries need more efficient organization since the customer expects a greater response to orders Due to this increased expectation, a supply chain management (SCM) has become one of the most important methods of competitive advantage in business today. This study has developed a simulator for the supply chain management problem. The simulator designed to help determine considering to the capacities and the costs of production and distribution facilities. The simulator developed using commercial simulation tool ARENA and the results of computational experiments for a simple example were given and discussed to validate the developed simulator. The simulator can be used to decide an realistic production-distribution planning in the area.

  • PDF

Miniaturization of Polymerase Chain Reaction

  • Lee, Ji-Youn;Kim, Jae-Jeong;Park, Tai-Hyun
    • Biotechnology and Bioprocess Engineering:BBE
    • /
    • v.8 no.4
    • /
    • pp.213-220
    • /
    • 2003
  • Polymerase chain reaction (PCR) is one of the most widely used analytical tool and is an important module that would benefit from being miniaturized and integrated onto diagnostic or analytical chips. There are potentially two different approaches for the miniaturization of the PCR module: chamber-type and flow-type micro-PCR. These miniaturized PCRs have distinct characteristics and advantages. In this article, we review the necessity of micro-PCR, the materials for the chip fabrication, the surface modification, and characteristics of the two types of micro-PCR. The motivation underlying the development of micro-PCR, the advantages and disadvantages of the various materials used in fabrication and the surface modification methods will be discussed. And finally, the precise features of the two different types of micro-PCR will be compared.

Genotyping of HLA-DRB1 by Polymerase Chain Reaction-Sequence Specific Primer (Polymerase Chain Reaction-Sequence Specific Primer를 이용한 HLA-DRB1 유전자의 DNA 다형성)

  • Jang, Soon-Mo
    • Korean Journal of Clinical Laboratory Science
    • /
    • v.37 no.3
    • /
    • pp.139-142
    • /
    • 2005
  • Most expressed HLA(human leukocyte antigen) loci exhibit a remarkable degree of allelic polymorphism, which is derived from sequenceing differences predominantly localized to discrete hypervariable regions of the amino-terminal domain of the molecule. In this study, the HLA-DRB1 genotypes were determined in twenty students using the PCR-SSP (polymerase chain reaction-sequence specific primer) technique. Two specific primer pairs in assigning the DRB1 gene were used. The results of PCR-SSP, the $HLA-DRB1^{\ast}0101$ primer detected nine and $HLA-DRB1^{\ast}1501$ primer detected three people. This study shows that the PCR-SSP technique is relatively simple, fast and a practical tool for the determination of the HLA-DRB1 genotypes. Moreover, these genotype frequency results of the HLA DRB1 gene could be useful for database study before being applied to individual identification and transplantation immunity.

  • PDF

A Study on the Expansion of the Global Supply Chain in Southeast Asia Using the FTA Outward Processing (FTA 역외가공방식을 활용한 동남아시아 지역의 글로벌 공급망 확대에 관한 연구)

  • Jin-Kyu Kim
    • Korea Trade Review
    • /
    • v.45 no.5
    • /
    • pp.223-238
    • /
    • 2020
  • In the environment of protectionism and bilateral trade agreements, Korea has promoted the conclusion of FTAs for its export-oriented trading policy, and 16 FTAs have entered into force at present. The main goal of this paper is to introduce the ISI system and its benefits and to extend the preferential rule of origin regime by using the Integrated Sourcing Initiative in the U.S. Code of Federal Regulations. The ISI illustrates with impressive clarity the fact that it considered as a tool of expanding the geographic limit of states and maximizing the global sourcing strategy of multinational corporations, allowing the developing countries to gain access to the market of developed ones that avoid the complexity and costs of many rules of origin regimes. This paper utilizes the literature research and analyzes a case study of FTAs which have adopted the ISI system. In conclusion, it presents several implications of additional measures to satisfy rules of origin in Korea's existing FTAs relating to the global supply chain strategy.

Accuracy Improvement of a 5-axis Hybrid Machine Tool (5축 혼합형 공작기계의 정밀도 향상 연구)

  • Kim, Han Sung
    • Journal of the Korean Society of Industry Convergence
    • /
    • v.17 no.3
    • /
    • pp.84-92
    • /
    • 2014
  • In this paper, a novel 5-axis hybrid-kinematic machine tool is introduced and the research results on accuracy improvement of the prototype machine tool are presented. The 5-axis hybrid machine tool is made up of a 3-DOF parallel manipulator and a 2-DOF serial one connected in series. The machine tool maintains high ratio of stiffness to mass due to the parallel structure and high orientation capability due to the serial-type wrist. In order to acquire high accuracy, the methodology of measuring the output shafts by additional sensors instead of using encoder outputs at the motor shafts is proposed. In the kinematic view point, the hybrid manipulator reduces to a serial one, if the passive joints in the U-P serial chain at the center of the parallel manipulator are directly measured by additional sensors. Using the method of successive screw displacements, the kinematic error model is derived. Since a ball-bar is less expensive than a full position measurement device and sufficiently accurate for calibration, the kinematic calibration method of using a ball-bar is presented. The effectiveness of the calibration method has been verified through the simulations. Finally, the calibration experiment shows that the position accuracy of the prototype machine tool has been improved from 153 to $86{\mu}m$.

Development of a Materials Management System Considering Construction Supply Chain Management (건설공급사슬을 고려한 건설공사 자재관리시스템 개발)

  • Jang, Myung-Hoon
    • Journal of the Korea Institute of Building Construction
    • /
    • v.9 no.5
    • /
    • pp.87-93
    • /
    • 2009
  • A construction supply chain needs an integrated information system, as the general contractor and subcontractors must communicate regularly with one another and share a substantial amount of information in their cooperative work. In the construction industry, supply chain management is necessary in the management of a system, including business process improvement, participant-oriented management, and the supply chain. This research proposed a supporting system and developed the prototype focusing on materials that play an important role in the supply chain. Construction projects are managed mainly through schedule management. As such, supply chain management should be linked with schedule management. The research implemented a prototype of the supporting system for construction supply chain management. The prototype was implemented in Microsoft Project using VBA, including a simulation tool based on @Risk for Project.

A DEVELOPMENT OF RFID/USN-BASED INTELLIGENT EQUIPMENT FOR CONSTRUCTION SUPPLY CHAIN MANAGEMENT

  • Tae-Hong Shin;Su-Won Yoon;Sangyoon Chin;Soon-Wook Kwon;Yea-Sang Kim;Cheolho Choi
    • International conference on construction engineering and project management
    • /
    • 2009.05a
    • /
    • pp.472-478
    • /
    • 2009
  • The scopes of the supply chain management in construction projects has expanded from the field management focusing on field storage, transportation, and lifting to the whole supply chain from the materials to field. The expansion of the supply chain management can raise the possibilities of leaner production, which enables shortened lead time of the difficult-to-operate materials, and prevents the work interference or delay. However, the expanded management range requires more information and management than an existing management style currently used for factory production of iron frame, curtain wall, PC, etc. In addition, there are limitations that expand the existing management style into the new supply chain management in construction projects and therefore it is required to automate the existing management style in order to extend the management range. The objective of this study is to propose the process and equipment that can manage the supply chain of the materials which range from the factory production to the field storage based on RFID/USN techniques, introducing small-sized transportation equipment(intelligent pallet), the vehicle tool kit(intelligent trailer), and in-and-out management equipment(Gate Sensor) as a prototype to effectively develop the appliances for operating the proposed process, and present the application possibility of the appliances. The full paper will present then the test results that the proposed appliances for the supply chain management automatically transmit and receive the generated information between the appliances or the appliance and sever under various wireless network circumstances such as zigbee, wibro, Wi-Fi, and CDMA.

  • PDF

A study on the Design of Drum Type Automatic Tool Changer (드럼형 자동공구교환장치의 설계에 관한 연구)

  • Choi, Hyun-Jin;Lee, Han-Gyu
    • Journal of the Korean Society of Manufacturing Process Engineers
    • /
    • v.19 no.7
    • /
    • pp.52-59
    • /
    • 2020
  • Automatic tool changers (ATCs) can be divided into drum and chain types. Drum-type ATCs contain a magazine, where the tools are mounted, and a cam gearbox, which swaps the tools via roller gear and grooved plate cams. Drum-type ATCs are advantageous in that the operating time for the tool magazine is more rapid than that of chain-type ATCs and the length of the unit is shorter. Thus, drum-type ATCs can be fabricated into various shapes and forms depending on the number of tools and the magazine size in accordance with machining center requirements and consumer demand. In particular, the price competitiveness of a machining center with a drum-type ATC is higher, while drum-type ATCs are more rigid with fewer parts, possibly reducing the need for regular servicing. This study aims to verify the structural stability and design validity of the magazine base, which is the main structure of a drum-type ATC, using finite element analysis. This study kinematically verifies the specifications of the selected drive motor and reducer and assessed the design of the cam gearbox. It also conducts a structural analysis of the roller camp, which is the core component of the cam gearbox, based on the results of the kinetodynamic analysis, thus validating the structural design.

Mobility Analysis of Closed-Chain Mechanisms with Lack of Geometric Generality

  • Yi, Byung-Ju;Yi, Dong;Kim, Whee-Kuk
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 2002.10a
    • /
    • pp.117.5-117
    • /
    • 2002
  • . Mobility analysis for overconstrained mechanisms is not clearly explained. . Aims at mobility analysis of overconstrained mechanisms . Representative screws is employed as a tool . A method to identifying the representative screw is introduced . Mobility analysis for several overconstrained parallel mechanisms and mobile robots

  • PDF

Bovine Embryo Sexing by Loop-Mediated Isothermal Amplification (LAMP

  • Kojiya, S.;Watanabe, K.
    • Proceedings of the KSAR Conference
    • /
    • 2004.06a
    • /
    • pp.183-183
    • /
    • 2004
  • In the bovine embryo transfer industry, sexing preimplantation embryos is an important management tool. Several methods for bovine embryo sexing utilizing polymerase chain reaction (PCR) have been developed. However, they were not popularized because the methods requiretechnical skills and expensive instruments, and are time consuming. PCR also has the risk of false positives due to DNA contamination during the electrophoresis. (omitted)

  • PDF