• Title/Summary/Keyword: Tolerance level

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Anti-obesity and Anti-diabetes Effects of the Fermented White Jelly Fungus (Tremella fuciformis Berk) Using Lactobacillus rhamnosus BHN-LAB 76 (유산균을 이용한 흰목이 버섯의 발효를 통한 항비만과 항당뇨 효과)

  • Lee, Jun-Hyeong;Kim, Byung-Hyuk;Yoon, Yeo-Cho;Kim, Jung-Gyu;Park, Ye-Eun;Park, Hye-Suk;Hwang, Hak-Soo;Kwun, In-Sook;Kwon, Gi-Seok;Lee, Jung-Bok
    • Journal of Life Science
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    • v.29 no.4
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    • pp.470-477
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    • 2019
  • White jelly fungus (Tremella fuciformis Berk) is effective for hypertension, diabetes, obesity, lung disease, beauty, and has been known as an elixir of life in ancient Chinese dynasty. In this study, we investigated the anti-obesity and diabetic effects of the fermented white jelly fungus extract by the bioconversion process. We fed an obesity-inducing mouse with 5% non-fermented Tremella fuciformis (TF), 2.5% fermented Tremella fuciformis (FTF), and 5% FTF containing High Fats Diet (HFD) and HFD for 8 weeks, respectively. The oral glucose tolerance test (OGTT) was performed analysis after 7 weeks of feeding and the dietary intake, food efficiency ratio, body weight, liver, epididymal fat weight, and serum insulin level were measured after 8 weeks of feeding. Also, HOMA-IR was analyzed. The concentrations of serum total cholesterol, triglycerides test was analyzed. The FTF compare with 5% TF and HFD confirmed that 5% FTF reduced body weight, tissue weight, triglycerides concentration, HOMA-IR, respectively. As a result, we confirmed that the fermented white jelly fungus has the anti-obesity effect. Finally, this study can be used a basic data for obesity treatment using fermented white jelly fungus.

Analysis of Elementary School Students' Visual Representation Competence for Shadow Phenomenon (그림자 현상에 대한 초등학생의 시각적 표상 능력)

  • Yoon, Hye-Gyoung
    • Journal of The Korean Association For Science Education
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    • v.39 no.2
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    • pp.295-305
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    • 2019
  • In previous study, visual representation competence taxonomy (VRC-T), which is composed of two dimensions, was developed for the purpose of promoting effective visual representation use and research in science education. In this study, elementary school students' visual representation competence for shadow phenomenon was investigated using VRC-T. In terms of visual representation competence, 'interpretation' was the highest score, followed by 'construction' and 'integration'. It also showed that students' visual representation competence was not high even after learning shadow-related units in the regular curriculum. On the other hand, text-based scientific knowledge was not correlated with all categories of visual representation competence. This indicates that there is a need to emphasize visual representation more in science class. Finally, hierarchical relationship among cognitive processes of VRC-T was explored according to ordering theory. If the tolerance level is somewhat loosened, a linear hierarchical relationship was found between the six cognitive processes. This suggests that VRC-T is an analytical framework that can be useful when designing assessment tools, tasks, and science class activities to enhance visual representation competence.

Quantitative Risk Assessment of Listeria monocytogenes Foodborne Illness Caused by Consumption of Cheese (위해평가를 통한 치즈에서의 Listeria monocytogenes 식중독 발생 가능성 분석)

  • Ha, Jimyeong;Lee, Jeeyeon
    • Journal of Food Hygiene and Safety
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    • v.35 no.6
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    • pp.552-560
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    • 2020
  • Listeria monocytogenes is a highly pathogenic gram-positive bacterium that is easily isolated from cheese, meat, processed meat products, and smoked salmon. A zero-tolerance (n=5, c=0, m=0/25 g) criteria has been applied for L. monocytogenes in cheese meaning that L. monocytogenes must not be detected in any 25 g of samples. However, there was a lack of scientific information behind this criteria. Therefore, in this study, we conducted a risk assessment based on literature reviews to provide scientific information supporting the baseline and to raise public awareness of L. monocytogenes foodborne illness. Quantitative risk assessment of L. monocytogenes for cheese was conducted using the following steps: exposure assessment, hazard characterization, and risk characterization. As a result, the initial contamination level of L. monocytogenes was -4.0 Log CFU/g in cheese. The consumption frequency of cheese was 11.8%, and the appropriate probability distribution for amount of cheese consumed was a Lognormal distribution with an average of 32.5 g. In conclusion, the mean of probabilities of foodborne illness caused by the consumption of cheese was 5.09×10-7 in the healthy population and 4.32×10-6 in the susceptible population. Consumption frequency has the biggest effect on the probability of foodborne illness, but storage and transportation times have also been found to affect the probability of foodborne illness; thus, management of the distribution environment should be considered important. Through this risk assessment, scientific data to support the criteria for L. monocytogenes in cheese could be obtained. In addition, we recommend that further risk assessment studies of L. monocytogenes in various foods be conducted in the future.

Risk Factors for Depression, Anxiety, and Stress in Patients with Polycystic Ovary Syndrome (다낭난소증후군 환자에서의 우울, 불안, 스트레스를 유발하는 위험 인자)

  • Park, Joon Cheol
    • Journal of the Korea Convergence Society
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    • v.13 no.3
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    • pp.337-343
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    • 2022
  • The aim of this study was to evaluate anxiety, depression and stress in women with polycystic ovary syndrome(PCOS) and to investigate the risk factors related to psychological difficulties. Sixty women with PCOS were evaluated for level of psychological stress using Beck depression inventory(BDI) and Depression anxiety stress scale(DASS) questionnaire. Serum antimullerian hormone, total testosterone, lutenizing hormone, follicle stimulating hormone, estradiol, lipid profile and 75g oral glucose tolerance test were measured. Thirty healthy women served as the control. Fifty two women with PCOS and 29 healthy women completed a questionnaire. Women with depression who scored >13 by BDI and >10 by DASS were 38.5 %, women with anxiety who scored >8 by DASS were 23.1 %, and women with stress who scored >15 by DASS were 30.8 %, which were significantly higher than control. In PCOS women, total testosterone, LH and AMH were significantly correlated with depression and stress. Weight, body mass index and waist-hip ratio were also significantly correlated with depression. In women diagnosed as diabetes and hyperlipidemia, depression and stress were significantly prevalent. Women with PCOS seemed to be more vulnerable to depression, anxiety and stress. Early diagnosis and management should be considered.

Enhancement of Photosynthetic Characteristics and Antioxidant Enzyme Activities on Chili Pepper Plants by Salicylic Acid Foliar Application under High Temperature and Drought Stress Conditions (고온 및 건조 스트레스 조건 하에서 살리실산 경엽처리에 의한 고추의 광합성 특성 및 항산화효소 활성 증대)

  • Lee, Jinhyoung;Lee, Heeju;Wi, Seunghwan;Lee, Hyejin;Choi, Haksoon;Nam, Chunwoo;Jang, Seonghoe
    • Journal of Bio-Environment Control
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    • v.31 no.4
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    • pp.311-318
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    • 2022
  • Salicylic acid (SA), a phenolic compound, plays a pivotal role in regulating a wide range of physiological and metabolic processes in plants such as antioxidant cellular defense, photosynthesis, and biotic and abiotic stress responses during the growth and development. We examined the effect of exogenous SA application (100 mg·L-1) on the growth, yield, photosynthetic characteristics, lipid peroxidation, and antioxidant enzyme activity of chili pepper plants under high temperature and drought stress conditions. SA treatment induced increases of net photosynthetic rate (Pn), stomatal conductance (Gs) and transpiration rate (Tr) under the stress condition with the highest level after the third treatment. The contents of malondialdehyde and H2O2 were significantly lower in the third treatment of SA compared to the control. The activity of ascorbate peroxidase, catalase, peroxidase and superoxide dismutase, increased in treated plants by up to 247, 318, 55 and 54%, respectively compared to the nontreated control. There was no significant difference in the growth characteristics between SA-treated and nontreated plants, while the SA treatment increased marketable yield (kg/10a) by about 15% compared to the nontreated control. Taken together, these results suggest that foliar application of SA alleviates physiological damages caused by the combination of drought and heat stress, and enhances the photosynthetic capacity and antioxidant enzyme activities, thereby improving tolerance to a combination of water deficit and heat stress in chili pepper plants.

Beneficial effect of Combination with Korean Red Ginseng and Morus alba in metabolic syndrome (고과당식이 랫드모델에서 홍삼과 상엽 혼합투여에 의한 대사증후군 개선효과)

  • Lee, Yun Jung;Kim, Hye Yoom;Yoon, Jung Joo;Lee, So Min;Ahn, You Mee;Kho, Joung Hyun;Kho, Min Chul;Lee, Ho Sub;Choi, Kyung Min;Kang, Dae Gill
    • The Korea Journal of Herbology
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    • v.27 no.6
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    • pp.99-105
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    • 2012
  • Objectives : Korean red ginseng and Morus alba L. are used as a traditional treatment for diabetes. This study was designed to elucidate whether combination with Korean red ginseng and Morus alba L. (MPM) ameliorates metabolic syndrome in fructose-fed rats. Methods : Animals were divided into four groups; Control receiving tap water, fructose-fed, rosiglitazone-treated fructose-fed rats, and MPM-treated fructose-fed rats both receiving supplemented with 60% fructose (n=10). The MPM or rosiglitazone groups initially received a high-fructose (HF) diet alone for 8 weeks, with supplementation with MPM or rosiglitazone occurring during the final 6 weeks. Results : MPM and rosiglitazone, synthetic $PPAR{\gamma}$ agonist, treatment significantly prevented the increase in fasting serum glucose, leptin, triglyceride, and low density lipoprotein in the HF group when comparing with the control group. MPM and rosiglitazone also led to an increase in high density lipoprotein level in the HF group. The administration of MPM and rosiglitazone prevented the development of the metabolic disturbances such as impaired glucose tolerance, and blood pressure. MPM suppressed increased expressions of endothelin-1 (ET-1) in HF rat aorta. In addition, MPM significantly increased IR-${\beta}$ and PPAR-${\gamma}$ expression in muscle. Conclusions : Based on these results, we suggest that the administration of MPM improves metabolic syndrome through the alteration in lipid profiles and suppression of insulin resistant and blood pressure.

Hypoglycemic Effects of Boiled rice made from Unpolished rice, Job' tear, and Extract From Medicinal Herbs Mixture on Diabetic Rat (당뇨 쥐에 대한 한약재복합추출물로 만든 현미율무밥의 혈당강하 효과)

  • Lee, Hyeon-Sun;Kong, Hyun-Joo;Lee, Eon-Hee;Hwang, Su-Jung;Jung, Hyeon-A;Kim, Mi-Lim;Choi, Eun-Mi;Jang, Joung-Hyeon;Yang, Kyung-Mi
    • The Korea Journal of Herbology
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    • v.29 no.3
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    • pp.59-70
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    • 2014
  • Objectives : The purpose of this study was to evaluate boiled rice made from unpolished rice, Job's Tears, and extract from medicinal herbs mixture (HGMCJE) for hypoglycemic effect on STZ-induced diabetic rats. Methods : In the response of glucose tolerance, control and diabetic rats groups was intubated with glucose and HGMCJE. Furthermore, boiled 100% polished rice (P rice), boiled unpolished rice mixed with white rice and Job's tears (polished rice:unpolished rice:Job's tears=60:25:15, UPJ-rice), and UPJ rice made from HGMCJE (HUPJ-rice) were intubated to control and diabetic rats groups, respectively. Then, blood glucose concentration, incremental blood glucose, and area under the curve (${\Delta}AUC$) were analyzed in every experimental groups, and these data were used to evaluate glycemic response. Results : When glucose and p rice were intubated in control and diabetic rats, blood glucose concentration, incremental blood glucose, and incremental response ${\Delta}AUC$ of diabetic groups were significantly increase than control groups. But administraion of a single dose of extract from medicinal herbs mixture and HUPJ-rice in control and diabetic rats inhibited the remarkable increase the level of postprandial blood and ${\Delta}AUC$ at 60, 90, and 120 min Conclusions : These results indicate that when intubation of glucose and P rice were out of control on postprandial glycemic response in diabetic rats. But postprandial glycemic response was well-modulated by administrating a single oral dose of HGMCJE and HUPJ-rice. Therefore, HGMCJE can be developed as an effective hypoglycemic agent.

Desalinization Effect of Pennisetum Alopecuroides and Characteristics of Leachate Depending on Calcium Chloride (CaCl2) Concentration

  • Yang, Ji;Yoon, Yong-Han;Ju, Jin-Hee
    • Journal of People, Plants, and Environment
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    • v.23 no.4
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    • pp.445-453
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    • 2020
  • Background and objective: Calcium chloride (CaCl2) and sodium chloride (NaCl) are commonly used as a deicing agent in South Korea and penetrate the soil on the roadside, causing damage to plants. This study was conducted to investigate the salinity reduction effect of Pennisetum alopecuroides and the chemical characteristics of soil leachate. Methods: The plants were treated with five different concentrations of CaCl2 (0, 1, 2, 5, and 10g·L-1) and were grouped into the Cont., C1, C2, C5, and C10 groups. CaCl2 of 200 m·L-1 was sprayed to each plant once every two weeks. The growth of P. alopecuroides (plant height, leaf length, leaf width and the number of leaves) was measured. The level of EC and pH, and exchangeable cations (K+, Ca2+, Na+, and Mg2+) in the leachate of soil was monitored. Results: The pH of soil leachate decreased as the CaCl2 concentration increased, and the EC increased significantly. The content of K+ did not change significantly until the concentration of CaCl2 reached 5 g·L-1, but the content of Ca2+, Na+, and Mg2+ significantly increased. The plant height, leaf length, and leaf width of P. alopecuroides showed the highest value in CaCl2 1 g·L-1 followed by CaCl2 2 g·L-1 and the control group. Root fresh weight was the highest in CaCl2 2 g·L-1. On the other hand, there was no change in the shoot fresh weight, dry weight and root dry weight, and P. alopecuroides growth inhibition at the concentration of 5 g·L-1 or higher in the plant height and leaf length. Conclusion: P. alopecuroides is relatively highly salt-tolerant and can improve the salt damaged soil by lowering the content of the salt-based exchangeable K+ ions.

The Effects of Self-Defense Categories, Rate of Self-Defense recognition in News Article, and the Individual Characteristics of Mock Jurors on the Self-Defense Judgment (정당방위 유형, 신문기사의 정당방위 인정비율, 판단자 개인 특성이 정당방위 판단에 미치는 영향)

  • Kim, Yong ae;Kim, Min Chi
    • Korean Journal of Forensic Psychology
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    • v.12 no.2
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    • pp.171-197
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    • 2021
  • The purpose of this study is to examine empirically how the lay people judge self-defense and what factors could affect it. A total of 651 participants aged 20 years and over were asked to answer, attitude toward interpersonal violence, and legal attitude questionnaire, all divided by the type of self-defense. Participants were assigned one of the three types of situations that were claimed to be self-defense, and were given articles and scenarios related to each type of self-defense before making self-defense judgments. In addition, the impact of personal factors on self-defense judgment was analyzed after the legal attitude, and the attitude toward interpersonal violence, which are personal factors, was also measured. The results showed that the rate of recognition of self-defense was the highest in the type of self-defense for oneself, but the rate of denial of self-defense against state agencies was much higher, indicating the opposite. Furthemore, negative articles on self-defense were found to affect the judgment of self-defense. In addition, it was found that the level of the attitude toward interpersonal violence and legal attitude of individual participants could affect the judgment of self-defense. The general public's judgment process and the factors that affect self-defense judgment may be considered to prevent biased judgment in actual jury trials. Finally, influence, and limitations of this study and suggestions of subsequent study were also discussed.

The Effects of TMT's Cognitive Traits and CEO Factors on R&D Investment (최고경영진의 인지적 특성과 최고경영자 특성이 R&D투자에 미치는 영향)

  • Hyejin Cho;Gahye Hong
    • Knowledge Management Research
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    • v.24 no.2
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    • pp.65-85
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    • 2023
  • This paper investigates how TMT's cognitive traits affect R&D investment. Drawing on the attention-based view, we propose that TMT's future orientation and risk preference increase the level of R&D investment. As R&D activities have long-term goal of generating proprietary knowledge, it is important to understand how TMT's attention toward future and risk affect R&D investment. Also, we test the moderating effect of CEO duality on R&D investment. As the CEO plays a leadership role in the TMT, if the CEO's decision-making authority is highly concentrated, the impact of TMT on R&D may decrease. We measure CEO duality and CEO ownership stake as CEO characteristics. Based on a sample of 837 U.S. manufacturing firms, the results show that when TMT has a higher tolerance for risk and higher future orientation, R&D intensity increases. However, when CEO also serves as chairman of board and CEO has higher ownership, TMT's influence on R&D investment weakens. This implies that TMT and CEO has power dynamic that can change based on CEO power supporting status. Overall, it suggests that TMT's attention and CEO power are important factors to improve longer-term knowledge accumulation of firm.