Browse > Article
http://dx.doi.org/10.6116/kjh.2014.29.3.59.

Hypoglycemic Effects of Boiled rice made from Unpolished rice, Job' tear, and Extract From Medicinal Herbs Mixture on Diabetic Rat  

Lee, Hyeon-Sun (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University)
Kong, Hyun-Joo (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University)
Lee, Eon-Hee (Department of Food and Nutrition, Graduate School, Yeungnam University)
Hwang, Su-Jung (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University)
Jung, Hyeon-A (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University)
Kim, Mi-Lim (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University)
Choi, Eun-Mi (Department of Food Science and Nutrition, Graduate School, Kyungpook National University)
Jang, Joung-Hyeon (Division of Cosmetology, Dong-Eui Institute of Technology)
Yang, Kyung-Mi (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University)
Publication Information
The Korea Journal of Herbology / v.29, no.3, 2014 , pp. 59-70 More about this Journal
Abstract
Objectives : The purpose of this study was to evaluate boiled rice made from unpolished rice, Job's Tears, and extract from medicinal herbs mixture (HGMCJE) for hypoglycemic effect on STZ-induced diabetic rats. Methods : In the response of glucose tolerance, control and diabetic rats groups was intubated with glucose and HGMCJE. Furthermore, boiled 100% polished rice (P rice), boiled unpolished rice mixed with white rice and Job's tears (polished rice:unpolished rice:Job's tears=60:25:15, UPJ-rice), and UPJ rice made from HGMCJE (HUPJ-rice) were intubated to control and diabetic rats groups, respectively. Then, blood glucose concentration, incremental blood glucose, and area under the curve (${\Delta}AUC$) were analyzed in every experimental groups, and these data were used to evaluate glycemic response. Results : When glucose and p rice were intubated in control and diabetic rats, blood glucose concentration, incremental blood glucose, and incremental response ${\Delta}AUC$ of diabetic groups were significantly increase than control groups. But administraion of a single dose of extract from medicinal herbs mixture and HUPJ-rice in control and diabetic rats inhibited the remarkable increase the level of postprandial blood and ${\Delta}AUC$ at 60, 90, and 120 min Conclusions : These results indicate that when intubation of glucose and P rice were out of control on postprandial glycemic response in diabetic rats. But postprandial glycemic response was well-modulated by administrating a single oral dose of HGMCJE and HUPJ-rice. Therefore, HGMCJE can be developed as an effective hypoglycemic agent.
Keywords
Korean traditional herbal extracts; anti-diabetic; postprandial glycemic response;
Citations & Related Records
Times Cited By KSCI : 20  (Citation Analysis)
연도 인용수 순위
1 Lee YT. Preparation and hypoglycemic effect of reconstituted grain added with selected medicinal herb extract. Korean J Food Sci Technol. 2003 ; 35(3) : 527-31.   과학기술학회마을
2 O'Dea K, Nestel PJ, Antonoff L. Physical factors influencing postprandial glucose and insulin responses to starch. Am J clin Nutr. 1980 ; 33(4) : 760-5.   DOI
3 Song SJ, Choi HN, Lee SY, Park JM, Kim BR, Paik HY, Song YJ. Establishing a table of glycemic index values for common Korean Foods and an Evaluation of the dietary glycemic index among the Korean adult population. Korean J Nutr. 2012 ; 45(1) : 80-93.   과학기술학회마을   DOI   ScienceOn
4 Sies H, Stahl W, Sevanian A. Nutritional, dietary and postprandial oxidative stress. J Nutr. 2005 ; 135(55) : 969-72.   DOI
5 Hennige AM, Burk DJ, Ozcan U, Kulkarni RN, Ye J, Park SM, Schubert M, Fisher TL, Dow MA, Leshan R, Zakaria M, Basha MM, White MF. Upregulation of insulin receptor substrate-2 in pancreatic $\beta$ cells prevents diabetes. J Clin Invest. 2003 ; 112(10) : 1521-32.   DOI   ScienceOn
6 Lee JS, Lee JS, Yang CB, Shin HK. Blood glucose Response to some cereals and determination of their glycemic index to rice as the standard food. Korean J Nutr. 1997 ; 30(10) : 1170-9.   과학기술학회마을
7 Nam MS, Kim KR, Cho JH, Lee KM, Park HY, Lee EJ, Lim SK, Lee HC, Huh KB. A Study on the Folk remedies by the questionaries in Korean Diabetic Patients. Diabetic. 1994 ; 18(30) : 242-8.
8 Park YJ, Lee YS, Hiramitsu S. Effect of coix on plasma cholesterol and lipid metabolism in rats. Korean J Nutr. 1988 ; 21(2) : 88-98.   과학기술학회마을
9 Park TS, Lee SY, Kim HJ, Kim KT, Kim YJ, Jeong IH, Do WN, Lee HJ. Extracts of Adlay, Barley and rice bran have antioxidant activity and modulate fatty acid metabolism in adipocytes. Korean J Food Nutr. 2009 ; 22(3) : 456-62.   과학기술학회마을
10 Lee C, Shin JS. Effects of different fiber content of rice on blood glucose and triglyceride levels in normal subject. J Korean Soc Food Sci Nutr. 2002 ; 31(6) : 1048-51.   과학기술학회마을   DOI   ScienceOn
11 Livesey G, Tagami H. Interventions to lower the glycemic response to carbohydrate foods with a low-viscosity fiber (resistant maltodextrin): meta-analysis of randomized controlled trials. Am J Clin Nutr. 2009 ; 89(1) : 114-25.   DOI
12 Keogh JB, Lau CW, Noakes M, Bowen J, Clifton PM. Effects of meals with high soluble fibre, high amylose barley variant on glucose, insulin, satiety and thermic effect of food in healthy lean women. Eur J Clin Nutr. 2007 ; 61(5) : 597-604.   DOI
13 Roberts SB. High-glycemic index foods, hunger, and obesity: is there a connection?. Nutr Rev. 2000 ; 58(6) : 163-9.
14 Haber GB, Heaton KW, Murphy D, Burroughs LF. Depletion and disruption of dietary fibre. effects on satiety, plasma-glucose, and serum-insulin. Lancet. 1977 ; 2(8040) : 679-82.
15 Pruessner JC, Kirschbaum C, Meinlschmid G, Hellharmmer DH. Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology. 2003 ; 28(7) : 916-31.   DOI   ScienceOn
16 Nelson N. A photometric adoption of the somogyi method for determination of glucose. J Biol Chem. 1944 ; 153(2) : 375-81.
17 Park KJ, Jin HS, Park SH, Kim EH, Kim JK. Antihyperglycemia effect of medicinal plants mixture in streptozotocin-induced diabetic rats. J Korean soc Food Sci Nutr. 2008 ; 37(12) : 1554-9.   과학기술학회마을   DOI   ScienceOn
18 Yun EK, Heo YR, Lim HS. Effects of Sasa Borealis Leaf Extract on the Glucose Tolerance of Major Foods for Carbohydrate. Korean J Nutr. 2010 ; 43(3) : 215-23.   과학기술학회마을   DOI   ScienceOn
19 Lee SJ, Shin JH, Ju JC, Kang SK, Sung NJ. Hypoglycemic and Hypolipidemic Effects of Orostachys japonicus with Medicinal Herbs in Streptozotocin- Induced Diabetic Rats. J Korean Soc Food Sci Nutr. 2013 ; 42(4) : 587-94.   과학기술학회마을   DOI   ScienceOn
20 Kim MH, Chung HK. Review of food therapy and development of diet therapy program for diabetes mellitus in Sikrychanyo. Korean J Food Culture. 2013 ; 28(6) : 562-75.   과학기술학회마을   DOI   ScienceOn
21 Lim JM, Kwon HJ, Yong SE, Choi JH, Lee CH, Kim TJ, Park PS, Choi YH, Kim EM, Park SY. Antioxidant Activity and Quality Characteristics of rice wine cakes cookies with different ratio of astragalus memvranaceus. Korean J Food Cookery Sci. 2013 ; 29(1) : 11-8.   과학기술학회마을   DOI   ScienceOn
22 Lee YK, Lee MY, Kim SD. Quality characteristics and dietary effect of Baguette bread added with water extracts of Liriopis Tuber on the blood glucose and serum cholesterol in diabetes induced rats. J East Asian Soc Dietary Life. 2004 ; 14(3) : 275-82.   과학기술학회마을
23 Park SH, Kim GY. Blood glucose level, insulin content and biochemical variables of complexcity extract from oriental medicinal plants on diabetes rats. Korean J Food Nutr. 2010 ; 23(2) : 258-68.   과학기술학회마을
24 Ahn DK. Shinnongbonchokyung. 1st rev. Korea : Esdang. 2012 : 61-4.
25 Jung ED. The Effects of Citri Unshii Pericarpium and its constituents on the stomach antrum and the hyperlipidemia. Graduate School of KyungHee University. 2007.
26 Hwang EY, hong JH, Choi JH, Lee EJ, Lee IS. Study on anti-obesity and hypoglycemic effects of Lycium chinense Mill extracts. J Korean Soc Food Sci Nutr. 2009 ; 38(11) : 1528-34.   과학기술학회마을   DOI   ScienceOn
27 Im JG, Kang MS, Park IK, Kim SD. Dietary effect of Liriopis tuber water extracts on the level of blood glucose and serum cholesterol in streptozotocin-induced diabetic rat. J East Asian Soc Dietary Life. 2005 ; 15(1) : 20-8.   과학기술학회마을
28 Hyon JS, Kang SM, Senevirathne M, Koh WJ, Yang TS, Oh MC, Oh CK, Jeon YJ, Kim SH. Antioxidative Activities of Dried and Fresh Citrus Peels in Jeju. Korean J Food Cookery Sci. 2010 ; 26(1) : 88-94.   과학기술학회마을
29 Kim JD. Literature on the quality and effect of Job's Tears (Coix lachryma -jobi L. var. mayuen S.). Korea Agric Hist Assoc. 2012 ; 11(1) : 89-122.
30 Kim DJ, Oh SK, Lee JH, Yoon MR, Choi IS, Lee DH, Kim YG. Changes in quality properties of brown rice after germination. Korean J Food Sci Technol. 2012 ; 44(3) : 300-5.   과학기술학회마을   DOI   ScienceOn
31 Cho EK, Jung KI, Choi YJ. anti-inflammatory and antidiabetic effects of brown rice (Oryza saliva L.) extracts. J Life Sci. 2012 ; 22(1) : 126-31.   과학기술학회마을   DOI   ScienceOn
32 Riccardi G, Rivellese AA, Giacco R. Role of glycemic index and glycemic load in the healthy state, in prediabeties, and in diabetes. Am J Clin Nutr. 2008 ; 87(1) : 269S-74S.   DOI
33 Rao Q, Labuza TP. Effect of moisture content on selected physiochemical properties of two commercial hen egg white powders. Food Chemistry. 2012 ; 132(1) : 373-4.   DOI   ScienceOn
34 AOAC. Official methods of analysis. 15th rev. Washington DC : Association of Analytical Chemists. 1984 : 210-9.
35 Lowry OH, Rosebrough NJ, Farr AL, Randal RJ. Protein measurement with folinphenol reagent. J Biol Chem. 1951 ; 193(1) : 265-75.
36 Foster-Powell K, Holt SH, Brand-Miller JC. International table of glycemic index and glycemic load values:2002. Am J Clin Nutr. 2012 ; 76(1) : 5-56.
37 Lee JS. Studies on in vitro starch hydrolysis and glycemic index of Korean cereals and legumes. Graduate School of Hanyang University. 1996.
38 Du H, van der A DL, van Bakel MM, van der Kallen CJ, Blaak EE, van Greevenbroek MM, Jansen EH, Nijpels G, Stehouwer CD, Dekker JM, Feskens EJ. Glycemic index and glycemic load in relation to food and nutrient intake and metabolic risk factors in a Dutch population. Am J Clin Nutr. 2008 ; 87(3) : 655-61.   DOI
39 Park ST, Jeong JC. Effects of Cheonghyul-san on blood glucose, hyperlipidemia, polyol pathway and reactive oxygen species in ob/ob mice. Korean J Orient physiol Pathol. 2008 ; 22(2) : 350-6.   과학기술학회마을
40 Xu YP. China Medical treatment of Endocrine metabolic diseases. Zhejiang : Zhejiang Science and Technology Publishing. 1992 : 239-43.
41 Kim IJ. Glycemic index. Korean Diabetes J. 2009 ; 33(4) : 261-6.   과학기술학회마을   DOI   ScienceOn
42 Choi JS, chang SK, Cho CS, Kim CJ, Han DU. Effect of Sopyung-tang extract on blood glucose & antioxidant enzyme activites of streptozotocin -induced diabetic rats. Korean J Orient Int Med. 2008 ; 29(1) : 90-103.
43 Ahn DK. Illustrated Book of Korean Medicinal Herbs. 7th rev. Korea : Kyo-Hak Publishing Co. 1998 : 702-945.
44 Jung HS, Lee EJ, Lee JH, Kim JS, Kang SS. Phytochemical studies on Astragalus root (3)-Triterpenoids and sterols. Korean J Pharmacogn. 2008 ; 39(3) : 186-93.   과학기술학회마을
45 Wolever TMS, Jenkins DJA, Collier GR, Lee R, Wong, GS, Josse RG. Metabolic response to test meals containing different carbohydrate foods: 1. relationship between rate of digestion and plasma insulin response. Nutr Res. 1988 ; 8(6) : 573-81.   DOI   ScienceOn
46 Jenkins DJ, Wolever TM, Jenkins AL. Starchy foods and glycemic index. Diabetes Care. 1988 ; 11(2) : 149-59.   DOI   ScienceOn
47 Pi-Sunyer FX. Glycemic index and disease. Am J Clin Nutr. 2002 ; 76(suppl) : 290S-8S.   DOI
48 Bornet FR, Fontvieille AM, Rizkalla S, Colonna P, Blayo A, Mercier C, Slama G. Insulin and glycemic responses in healthy humans to native starches processed in different ways: Correlation with in vitro $\alpha$-amylose hydrolysis. Am J Clin Nutr. 1989 ; 50(2) : 315-23.   DOI
49 Brand JC, Colagiuri S, crossman FS, Allen CA, Robert DCK, truswell AS. Low-glycemic index foods improve long-term glycemic control in NIDDM. Diabetes Care. 1991 ; 14(2) : 95-101.   DOI   ScienceOn
50 Fang YJ. Practical China Medical Internal Medicine, Shanghai : Shanghai Science and Technology Publishing. 1986 : 477.